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furlong

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4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science, Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

sciencescience-technology

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science, Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

2 February 2012 Fruit fly embryo showing the cells that will become the gut and heart

Collective action

Science, Science & Technology If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…

2012

sciencescience-technology

8 January 2012 Diagram of chromatin enhancers

Tracking genes’ remote controls

Science, Science & Technology As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…

2012

sciencescience-technology

4 November 2009 fluorescence microscopy images of fruit fly embryos

Deciphering the regulatory code

Science Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…

2009

science

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