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Furlong Archives | EMBL

The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.

By Iris Kruijen

Science

Information (arrows) emanating out of chromatin to give rise to different cell types. IMAGE: Campbell Medical Illustration

Chromatin usage reveals developmental trajectories

EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories

By Iris Kruijen

Science

Enhancer activity (green) and promoter activity (purple) in the same regulatory element. IMAGE: EMBL / Eileen Furlong

Multipurpose enhancers and promoters in embryonic development

EMBL scientists show that some promoters can act as enhancers and vice versa

By Iris Kruijen

Science

Futures: Genome regulation

ERC grantee Eileen Furlong shares her vision for the next ten years

By Edward Dadswell

Science

Genetic switches can change shape

EMBL scientists discovered that common mutations can change the shape of gene promoters

By Sonia Furtado Neves

Science

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