Publications – Ephrussi Group

Bassett AR, Akhtar A, Barlow DP, Bird AP, Brockdorff N, Duboule D, Ephrussi A, Ferguson-Smith AC, Gingeras TR, Haerty W, Higgs DR, Miska EA, Ponting CP

eLife, 2014

doi:10.7554/elife.03058.

Klar ensures thermal robustness of oskar localization by restraining RNP motility.

Gaspar I, Yu YV, Cotton SL, Kim DH, Ephrussi A, Welte MA

The Journal of cell biology, 2014

doi:10.1083/jcb.201310010.

The EJC binding and dissociating activity of PYM is regulated in Drosophila.

Ghosh S, Obrdlik A, Marchand V, Ephrussi A

PLoS genetics, 2014

doi:10.1371/journal.pgen.1004455.

RNA clamping by vasa assembles a piRNA amplifier complex on transposon transcripts.

Xiol J, Spinelli P, Laussmann MA, Homolka D, Yang Z, Cora E, Couté Y, Conn S, Kadlec J, Sachidanandam R, Kaksonen M, Cusack S, Ephrussi A, Pillai RS

Cell, 2014

doi:10.1016/j.cell.2014.05.018.

A stem-loop structure directs oskar mRNA to microtubule minus ends.

Jambor H, Mueller S, Bullock SL, Ephrussi A

RNA (New York, N.Y.), 2014

doi:10.1261/rna.041566.113.

Imp promotes axonal remodeling by regulating profilin mRNA during brain development.

Medioni C, Ramialison M, Ephrussi A, Besse F

Current biology : CB, 2014

doi:10.1016/j.cub.2014.02.038.

Brightness enhanced DNA FIT-probes for wash-free RNA imaging in tissue.

Hövelmann F, Gaspar I, Ephrussi A, Seitz O

Journal of the American Chemical Society, 2013

doi:10.1021/ja410674h.

A single Drosophila embryo extract for the study of mitosis ex vivo.

Telley IA, Gáspár I, Ephrussi A, Surrey T

Nature protocols, 2013

doi:10.1038/nprot.2013.003.

A Cdc42-regulated actin cytoskeleton mediates Drosophila oocyte polarization.

Leibfried A, Müller S, Ephrussi A

Development (Cambridge, England), 2013

doi:10.1242/dev.089250.

Aster migration determines the length scale of nuclear separation in the Drosophila syncytial embryo.

Telley IA, Gáspár I, Ephrussi A, Surrey T

The Journal of cell biology, 2012

doi:10.1083/jcb.201204019.

Control of RNP motility and localization by a splicing-dependent structure in oskar mRNA.

Ghosh S, Marchand V, Gáspár I, Ephrussi A

Nature structural & molecular biology, 2012

doi:10.1038/nsmb.2257.

An intracellular transmission control protocol: assembly and transport of ribonucleoprotein complexes.

Marchand V, Gaspar I, Ephrussi A

Current opinion in cell biology, 2012

doi:10.1016/j.ceb.2011.12.014.

Dimerization of oskar 3' UTRs promotes hitchhiking for RNA localization in the Drosophila oocyte.

Jambor H, Brunel C, Ephrussi A

RNA (New York, N.Y.), 2011

doi:10.1261/rna.2686411.

Drosophila Ge-1 promotes P body formation and oskar mRNA localization.

Fan SJ, Marchand V, Ephrussi A

PloS one, 2011

doi:10.1371/journal.pone.0020612.

Retraction notice to: assembly of endogenous oskar mRNA particles for motor-dependent transport in the Drosophila oocyte.

Trucco A, Gaspar I, Ephrussi A

Cell, 2010

doi:10.1016/j.cell.2010.10.011.

Myosin-V regulates oskar mRNA localization in the Drosophila oocyte.

Krauss J, López de Quinto S, Nüsslein-Volhard C, Ephrussi A

Current biology : CB, 2009

doi:10.1016/j.cub.2009.04.062.

mRNA localization: gene expression in the spatial dimension.

Martin KC, Ephrussi A

Cell, 2009

doi:10.1016/j.cell.2009.01.044.

Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation.

Besse F, López de Quinto S, Marchand V, Trucco A, Ephrussi A

Genes and Development , 2009

doi:10.1101/gad.505709.

The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.

Suyama R, Jenny A, Curado S, Pellis-van Berkel W, Ephrussi A

Development (Cambridge, England), 2009

doi:10.1242/dev.027698.

Translational control of localized mRNAs: restricting protein synthesis in space and time.

Besse F, Ephrussi A

Nature reviews. Molecular cell biology, 2008

doi:10.1038/nrm2548.

Drosophila ensconsin promotes productive recruitment of Kinesin-1 to microtubules.

Sung HH, Telley IA, Papadaki P, Ephrussi A, Surrey T, Rørth P

Developmental cell, 2008

doi:10.1016/j.devcel.2008.10.006.

Germ plasm formation and germ cell determination in Drosophila.

Lehmann R, Ephrussi A

Ciba Foundation symposium, 2007

doi:10.1002/9780470514573.ch16.

The Ig cell adhesion molecule Basigin controls compartmentalization and vesicle release at Drosophila melanogaster synapses.

Besse F, Mertel S, Kittel RJ, Wichmann C, Rasse TM, Sigrist SJ, Ephrussi A

The Journal of cell biology, 2007

doi:10.1083/jcb.200701111.

Rab6 mediates membrane organization and determinant localization during Drosophila oogenesis.

Coutelis JB, Ephrussi A

Development (Cambridge, England), 2007

doi:10.1242/dev.02821.

Stimulation of endocytosis and actin dynamics by Oskar polarizes the Drosophila oocyte.

Vanzo N, Oprins A, Xanthakis D, Ephrussi A, Rabouille C

Developmental cell, 2007

doi:10.1016/j.devcel.2007.03.002.

Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila.

Anne J, Ollo R, Ephrussi A, Mechler BM

Development (Cambridge, England), 2007

doi:10.1242/dev.02687.

A translation-independent role of oskar RNA in early Drosophila oogenesis.

Jenny A, Hachet O, Závorszky P, Cyrklaff A, Weston MD, Johnston DS, Erdélyi M, Ephrussi A

Development (Cambridge, England), 2006

doi:10.1242/dev.02456.

Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles.

Chekulaeva M, Hentze MW, Ephrussi A

Cell, 2006

doi:10.1016/j.cell.2006.01.031.

Gain-of-function screen for genes that affect Drosophila muscle pattern formation.

Staudt N, Molitor A, Somogyi K, Mata J, Curado S, Eulenberg K, Meise M, Siegmund T, Häder T, Hilfiker A, Brönner G, Ephrussi A, Rørth P, Cohen SM, Fellert S, Chung HR, Piepenburg O, Schäfer U, Jäckle H, Vorbrüggen G

PLoS genetics, 2005

doi:10.1371/journal.pgen.0010055.

The Drosophila PAR-1 spacer domain is required for lateral membrane association and for polarization of follicular epithelial cells.

Vaccari T, Rabouille C, Ephrussi A

Current biology : CB, 2005

doi:10.1016/j.cub.2005.01.033.

Par-1 regulates bicoid mRNA localisation by phosphorylating Exuperantia.

Riechmann V, Ephrussi A

Development (Cambridge, England), 2004

doi:10.1242/dev.01515.

Drosophila development: RNA interference ab ovo.

Chekulaeva M, Ephrussi A

Current biology : CB, 2004

doi:10.1016/j.cub.2004.05.036.

Hrp48, a Drosophila hnRNPA/B homolog, binds and regulates translation of oskar mRNA.

Yano T, López de Quinto S, Matsui Y, Shevchenko A, Shevchenko A, Ephrussi A

Developmental cell, 2004

doi:10.1016/s1534-5807(04)00132-7.

Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization.

Hachet O, Ephrussi A

Nature, 2004

doi:10.1038/nature02521.

PKA-R1 spatially restricts Oskar expression for Drosophila embryonic patterning.

Yoshida S, Müller HA, Wodarz A, Ephrussi A

Development (Cambridge, England), 2004

doi:10.1242/dev.01034.

Seeing is believing: the bicoid morphogen gradient matures.

Ephrussi A, St Johnston D

Cell, 2004

doi:10.1016/s0092-8674(04)00037-6.

Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism.

Teixeira L, Rabouille C, Rørth P, Ephrussi A, Vanzo NF

Mechanisms of development, 2003

doi:10.1016/s0925-4773(03)00158-8.

Pattern formation and developmental mechanisms - From cell patterning to organogenesis - Editorial overview.

Ephrussi A, Pourquie O

Current opinion in genetics and development, 2003

doi:10.1016/S0959-437X(03)00092-3.

Orb and a long poly(A) tail are required for efficient oskar translation at the posterior pole of the Drosophila oocyte.

Castagnetti S, Ephrussi A

Development , 2003

doi:10.1242/dev.00309.

Bruno regulates gurken during Drosophila oogenesis.

Filardo P, Ephrussi A

Mechanisms of development, 2003

doi:10.1016/s0925-4773(02)00454-9.

The fusome and microtubules enrich Par-1 in the oocyte, where it effects polarization in conjunction with Par-3, BicD, Egl, and dynein.

Vaccari T, Ephrussi A

Current biology : CB, 2002

doi:10.1016/s0960-9822(02)01079-5.

Oskar anchoring restricts pole plasm formation to the posterior of the Drosophila oocyte.

Vanzo NF, Ephrussi A

Development , 2002

doi:10.1242/dev.129.15.3705.

Par-1 regulates stability of the posterior determinant Oskar by phosphorylation.

Riechmann V, Gutierrez GJ, Filardo P, Nebreda AR, Ephrussi A

Nature cell biology, 2002

doi:10.1038/ncb782.

A germline-specific gap junction protein required for survival of differentiating early germ cells.

Tazuke SI, Schulz C, Gilboa L, Fogarty M, Mahowald AP, Guichet A, Ephrussi A, Wood CG, Lehmann R, Fuller MT

Development (Cambridge, England), 2002

doi:10.1242/dev.129.10.2529.

Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport.

Hachet O, Ephrussi A

Current biology : CB, 2001

doi:10.1016/s0960-9822(01)00508-5.

Axis formation during Drosophila oogenesis.

Riechmann V, Ephrussi A

Current opinion in genetics & development, 2001

doi:10.1016/s0959-437x(00)00207-0.

A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation.

Tomancak P, Piano F, Riechmann V, Gunsalus KC, Kemphues KJ, Ephrussi A

Nature cell biology, 2000

doi:10.1038/35017101.

Tribbles coordinates mitosis and morphogenesis in Drosophila by regulating string/CDC25 proteolysis.

Mata J, Curado S, Ephrussi A, Rørth P

Cell, 2000

doi:10.1016/s0092-8674(00)80861-2.

Control of oskar mRNA translation by Bruno in a novel cell-free system from Drosophila ovaries.

Castagnetti S, Hentze MW, Ephrussi A, Gebauer F

Development (Cambridge, England), 2000

doi:10.1242/dev.127.5.1063.

Relief of gene repression by torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning.

Jiménez G, Guichet A, Ephrussi A, Casanova J

Genes & development, 2000

doi:10.1101/gad.14.2.224.

Localization-dependent translation requires a functional interaction between the 5' and 3' ends of oskar mRNA.

Gunkel N, Yano T, Markussen FH, Olsen LC, Ephrussi A

Genes & development, 1998

doi:10.1101/gad.12.11.1652.

Oocyte polarity depends on regulation of gurken by Vasa.

Tomancak P, Guichet A, Zavorszky P, Ephrussi A

Development (Cambridge, England), 1998

doi:10.1242/dev.125.9.1723.

Analysis of RNA distribution during Drosophila oogenesis using fluorescent in situ hybridization.

Glotzer JB, Ephrussi A

1997

doi:.

Cytoplasmic flows localize injected oskar RNA in Drosophila oocytes.

Glotzer JB, Saffrich R, Glotzer M, Ephrussi A

Current biology : CB, 1997

doi:10.1016/s0960-9822(06)00156-4.

Ftz-F1 is a cofactor in Ftz activation of the Drosophila engrailed gene.

Florence B, Guichet A, Ephrussi A, Laughon A

Development (Cambridge, England), 1997

doi:10.1242/dev.124.4.839.

The nuclear receptor homologue Ftz-F1 and the homeodomain protein Ftz are mutually dependent cofactors.

Guichet A, Copeland JW, Erdélyi M, Hlousek D, Závorszky P, Ho J, Brown S, Percival-Smith A, Krause HM, Ephrussi A

Nature, 1997

doi:10.1038/385548a0.

Efficient translation and phosphorylation of Oskar require Oskar protein and the RNA helicase Vasa.

Markussen FH, Breitwieser W, Ephrussi A

Cold Spring Harbor symposia on quantitative biology, 1997

doi:.

Oskar protein interaction with Vasa represents an essential step in polar granule assembly.

Breitwieser W, Markussen FH, Horstmann H, Ephrussi A

Genes & development, 1996

doi:10.1101/gad.10.17.2179.

mRNA localization and the cytoskeleton.

Glotzer JB, Ephrussi A

Seminars in cell & developmental biology, 1996

doi:10.1006/scdb.1996.0045.

Translational control of oskar generates short OSK, the isoform that induces pole plasma assembly.

Markussen FH, Michon AM, Breitwieser W, Ephrussi A

Development (Cambridge, England), 1995

doi:10.1242/dev.121.11.3723.

Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization.

Erdélyi M, Michon AM, Guichet A, Glotzer JB, Ephrussi A

Nature, 1995

doi:10.1038/377524a0.

Induction of germ cell formation by oskar.

Ephrussi A, Lehmann R

Nature, 1992

doi:10.1038/358387a0.

Oskar organizes the germ plasm and directs localization of the posterior determinant nanos.

Ephrussi A, Dickinson LK, Lehmann R

Cell, 1991

doi:10.1016/0092-8674(91)90137-n.

Cell-type-specific contacts to immunoglobulin enhancers in nuclei.

Church GM, Ephrussi A, Gilbert W, Tonegawa S

Nature, 1985

doi:10.1038/313798a0.

B lineage--specific interactions of an immunoglobulin enhancer with cellular factors in vivo.

Ephrussi A, Church GM, Tonegawa S, Gilbert W

Science , 1985

doi:10.1126/science.3917574.