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Cusack Group

Structural biology of RNA-protein complexes in gene expression and host-pathogen interactions

Publications

NCBP3 positively impacts mRNA biogenesis.

Dou Y, Barbosa I, Jiang H, Iasillo C, Molloy KR, Schulze WM, Cusack S, Schmid M, Le Hir H, LaCava J, Jensen TH

Nucleic acids research 2020

32960271. doi:10.1093/nar/gkaa744.

Discovery of a novel class of boron-based antibacterials with activity against gram-negative bacteria

Hernandez V, Crépin T, Palencia A, Cusack S, Akama T, Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang YK, Zhou Y, Nieman JA, Anugula MR, Keramane el M, Savariraj K, Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley MR, Plattner JJ

Antimicrobial agents and chemotherapy 2013

23295920. doi:10.1128/aac.02058-12.

Structural insights into the Slit-Robo complex

Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA

Proceedings of the National Academy of Sciences of the United States of America 2007

17848514. doi:10.1073/pnas.0705310104.

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

Beteva A, Cipriani F, Cusack S, Delageniere S, Gabadinho J, Gordon EJ, Guijarro M, Hall DR, Larsen S, Launer L, Lavault CB, Leonard GA, Mairs T, McCarthy A, McCarthy J, Meyer J, Mitchell E, Monaco S, Nurizzo D, Pernot P, Pieritz R, Ravelli RG, Rey V, Shepard W, Spruce D, Stuart DI, Svensson O, Theveneau P, Thibault X, Turkenburg J, Walsh M, McSweeney SM

Acta crystallographica. Section D, Biological crystallography 2006

17001093. doi:10.1107/s0907444906032859.

Automation of sample mounting for macromolecular crystallography

Cipriani F, Felisaz F, Launer L, Aksoy JS, Caserotto H, Cusack S, Dallery M, di-Chiaro F, Guijarro M, Huet J, Larsen S, Lentini M, McCarthy J, McSweeney S, Ravelli R, Renier M, Taffut C, Thompson A, Leonard GA, Walsh MA

Acta crystallographica. Section D, Biological crystallography 2006

17001102. doi:10.1107/s0907444906030587.

Contributions of conformational flexibility to Brugia malayi asparaginyl-tRNA synthetase specificity for inhibitors identified by structure-based screening

Sukuru SCK, Crepin T, Morris JC, Grotli M, Danel F, Page MGP, Haertlein M, Cusack S, Kron MA, Kuhn LA

Abstracts of papers of the American Chemical Society 2006

doi:.

Prolyl-tRNA synthetase

Musier-Forsyth K, Burke B, Cusack, S

2005

doi:.

Seryl-tRNA Synthetases

Weygand-Durasevic I, Cusack S

2005

doi:.

Significance of the first transcribed nucleoside of capped RNA for ligand-induced folding of the cap-binding complex

Worch R, Niedzwiecka A, Stepinski J, Jankowska-Anyszka M, Mazza C, Darzynkiewicz E, Cusack S, Stolarski R

Journal of physics. Condensed matter : an Institute of Physics journal 2005

doi:.

Structure, folding and assembly of adenovirus fibers

Mitraki A, Raaij M, Ruigrok R, Cusack S, Hernandez J-F, Luckey M

2001

doi:10.1007/0-306-46890-5_16.

RNA-protein complexes

Cusack S

Current opinion in structural biology 1999

10400475. doi:10.1016/s0959-440x(99)80009-8.

tRNA recognition by aminoacyl-tRNA synthetases

Cusack S, Yaremchuk Y, Tukalo M

1998

doi:10.1016/B978-012233210-4/50005-0.

Neutron scattering.

Cusack S, Jacrot B, Leberman R, May R, Timmins P, Zaccai G

Nature 1989

2657433. doi:10.1038/339330a0.


Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase.

Kouba T, Koval' T, Sudzinová P, Pospíšil J, Brezovská B, Hnilicová J, Šanderová H, Janoušková M, Šiková M, Halada P, Sýkora M, Barvík I, Nováček J, Trundová M, Dušková J, Skálová T, Chon U, Murakami KS, Dohnálek J, Krásný L

Nature communications 2020

33339823. doi:10.1038/s41467-020-20158-4.

NCBP3 positively impacts mRNA biogenesis.

Dou Y, Barbosa I, Jiang H, Iasillo C, Molloy KR, Schulze WM, Cusack S, Schmid M, Le Hir H, LaCava J, Jensen TH

Nucleic acids research 2020

32960271. doi:10.1093/nar/gkaa744.

Discovery of a novel class of boron-based antibacterials with activity against gram-negative bacteria

Hernandez V, Crépin T, Palencia A, Cusack S, Akama T, Baker SJ, Bu W, Feng L, Freund YR, Liu L, Meewan M, Mohan M, Mao W, Rock FL, Sexton H, Sheoran A, Zhang Y, Zhang YK, Zhou Y, Nieman JA, Anugula MR, Keramane el M, Savariraj K, Reddy DS, Sharma R, Subedi R, Singh R, O'Leary A, Simon NL, De Marsh PL, Mushtaq S, Warner M, Livermore DM, Alley MR, Plattner JJ

Antimicrobial agents and chemotherapy 2013

23295920. doi:10.1128/aac.02058-12.

CC2D1A is a regulator of ESCRT-III CHMP4B

Martinelli N, Hartlieb B, Usami Y, Sabin C, Dordor A, Miguet N, Avilov SV, Ribeiro EA Jr, Göttlinger H, Weissenhorn W

Journal of molecular biology 2012

22406677. doi:10.1016/j.jmb.2012.02.044.

Structural insights into the Slit-Robo complex

Morlot C, Thielens NM, Ravelli RB, Hemrika W, Romijn RA, Gros P, Cusack S, McCarthy AA

Proceedings of the National Academy of Sciences of the United States of America 2007

17848514. doi:10.1073/pnas.0705310104.

High-throughput sample handling and data collection at synchrotrons: embedding the ESRF into the high-throughput gene-to-structure pipeline

Beteva A, Cipriani F, Cusack S, Delageniere S, Gabadinho J, Gordon EJ, Guijarro M, Hall DR, Larsen S, Launer L, Lavault CB, Leonard GA, Mairs T, McCarthy A, McCarthy J, Meyer J, Mitchell E, Monaco S, Nurizzo D, Pernot P, Pieritz R, Ravelli RG, Rey V, Shepard W, Spruce D, Stuart DI, Svensson O, Theveneau P, Thibault X, Turkenburg J, Walsh M, McSweeney SM

Acta crystallographica. Section D, Biological crystallography 2006

17001093. doi:10.1107/s0907444906032859.

Automation of sample mounting for macromolecular crystallography

Cipriani F, Felisaz F, Launer L, Aksoy JS, Caserotto H, Cusack S, Dallery M, di-Chiaro F, Guijarro M, Huet J, Larsen S, Lentini M, McCarthy J, McSweeney S, Ravelli R, Renier M, Taffut C, Thompson A, Leonard GA, Walsh MA

Acta crystallographica. Section D, Biological crystallography 2006

17001102. doi:10.1107/s0907444906030587.

Contributions of conformational flexibility to Brugia malayi asparaginyl-tRNA synthetase specificity for inhibitors identified by structure-based screening

Sukuru SCK, Crepin T, Morris JC, Grotli M, Danel F, Page MGP, Haertlein M, Cusack S, Kron MA, Kuhn LA

Abstracts of papers of the American Chemical Society 2006

doi:.

Prolyl-tRNA synthetase

Musier-Forsyth K, Burke B, Cusack, S

2005

doi:.

Seryl-tRNA Synthetases

Weygand-Durasevic I, Cusack S

2005

doi:.

Significance of the first transcribed nucleoside of capped RNA for ligand-induced folding of the cap-binding complex

Worch R, Niedzwiecka A, Stepinski J, Jankowska-Anyszka M, Mazza C, Darzynkiewicz E, Cusack S, Stolarski R

Journal of physics. Condensed matter : an Institute of Physics journal 2005

doi:.

Structure, folding and assembly of adenovirus fibers

Mitraki A, Raaij M, Ruigrok R, Cusack S, Hernandez J-F, Luckey M

2001

doi:10.1007/0-306-46890-5_16.

RNA-protein complexes

Cusack S

Current opinion in structural biology 1999

10400475. doi:10.1016/s0959-440x(99)80009-8.

tRNA recognition by aminoacyl-tRNA synthetases

Cusack S, Yaremchuk Y, Tukalo M

1998

doi:10.1016/B978-012233210-4/50005-0.

Neutron scattering.

Cusack S, Jacrot B, Leberman R, May R, Timmins P, Zaccai G

Nature 1989

2657433. doi:10.1038/339330a0.

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