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The epitranscriptome – Course and Conference Office

EMBO Workshop

The epitranscriptome

Overview

Conference Overview

The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. It is now emerging that the modification status of the transcriptome is dynamic and responsive to environmental/developmental cues. Together, this has elicited the realisation of an ‘epitranscriptome’ where post-transcriptional RNA modification coupled with recruitment of effector RNA binding proteins dynamically regulates genomic output. Importantly, mutations in setting or reading RNA modifications are causative of many human diseases or congenital disorders. This meeting aims to explore all aspects of this emerging topic, from methods development to molecular mechanism. Most importantly, the meeting will place an emphasis on the contribution of RNA modification to mammalian development, tissue homeostasis and disease.

Session Topics

  • RNA modification I
  • RNA modifications in stem cells and development
  • RNA modification II
  • RNA modification pathways in physiology and pathology
  • Emerging concepts

What past participants say about the conference:

“The Epitranscriptome EMBL conference rapidly became a must in the field.” – Mattia Pelizzola, Istituto Italiano di Tecnologia, Italy.

“The conference provided an excellent opportunity to get the latest insights in the field of epitranscriptomics, presented by the world-leading academic groups.” – Gerhard Müller, Gotham Therapeutics, New York, USA.

“This conference was really good for me. I have learnt about new RNA regulatory mechanisms, especially m6A and how it’s an important target for RNA processing.” – Opeyemi Olotu, University of Turku, Finland.

Speakers

Keynote Speaker

Chuan He

The University of Chicago

USA

Speakers

Janusz Bujnicki

International Institute of Molecular and Cell Biology

Poland

Stefanie Kellner-Kaiser

Goethe University Frankfurt

Germany

Kamil Kranc

Barts Cancer Institute, Queen Mary University of London

UK

Yunsun Nam

The University of Texas Southwestern Medical Center

USA

Scientific Organisers

Conference Organisers

Lea Hohmann

EMBL Heidelberg

Germany

Aline Schnieder

EMBL Heidelberg

Germany

Preliminary Programme

Got something to say? Tweet it! #EMBOEpitrans

  • The virtual conference includes live-streamed invited speakers and short talk presenters with Q&A sessions after each talk.
  • Information on the live stream and access to the discussion platform and digital posters will be provided shortly before the start of the event.
  • Access to the recorded talks will be available for 2 weeks after the end of the event.

The following time is used in the programme below:

  • Europe/Berlin

To find out the equivalent time zone in your location, enter Berlin, the programme time and your city into the Time Zone Converter.

Day 1 – Wednesday, 9 February 2022
Time (Europe/Berlin) Speaker
14:00-14:15Opening remarks by Scientific Organisers
Session 1: RNA modification I
Chair: tba
14:15-15:15Keynote lecture: RNA methylation in gene expression regulation
Chuan He – The University of Chicago, USA
15:15-15:30Selected short talk 1
15:30-16:00Deciphering the specificity and regulation of the m6A writer complex
Samie Jaffrey – Weill Cornell Medicine, USA
16:00-16:15Selected short talk 2
16:15-16:30Break
16:30-17:00Biochemical characterization of the mouse piRNA methyltransferase mHEN1
Ramesh Pillai – University of Geneva, Switzerland
17:00-17:15Selected short talk 3
17:15-17:30Selected short talk 4
17:30-18:00Meet the Speakers of Session 1
18:00-19:00Poster session 1
19:00-19:30Optional Social Programme: Speed networking
Day 2 – Thursday, 10 February 2022
Time
(Europe/Berlin)
Speaker
Session 2: RNA modifications in stem cells and development
Chair: tba
14:00-14:30Role of the ‘Epitranscriptome’ in gene regulation and cancer
Richard Gregory – Boston Children’s Hospital, USA
14:30-14:45Selected short talk 5
14:45-15:15Selective translation control by pseudouridine-modified tRNA fragments in stem and cancer cells
Cristian Bellodi – Lund University, Sweden
15:15-15:30Break
15:30-16:00Is m6A dynamic?
Schraga Schwartz – Weizmann Institute of Science, Israel
16:00-16:15Selected short talk 6
16:15-16:45Meet the speakers of Session 2
16:45-17:45Poster session 2
Session 3: RNA modification II
Chair: tba
17:45-18:15RNA modifications and RNA 3D structure
Janusz Bujnicki – International Institute of Molecular and Cell Biology, Poland
18:15-18:30Selected short talk 7
18:30-19:00Talk title to be announced
Yunsun Nam, The University of Texas Southwestern Medical Center, USA
19:00-19:15Break
19:15-19:45Talk title to be announced
Shalini Oberdoerffer – National Cancer Institute, USA
19:45-20:00Selected short talk 8
20:00-20:30What spatial interactions can tell us about the function of m6A and m6Am factors
Štěpánka Vaňáčová – CEITEC, Czech Republic
20:30-21:00Meet the speakers of Session 3
Day 3 – Friday, 11 February 2022
Time
(Europe/Berlin)
Speaker
Session 4: RNA modification pathways in physiology and pathology
Chair: tba
14:00-14:30The impact of uridylation and m6A modification of RNA on normal and malignant haematopoiesis
Kamil Kranc – Barts Cancer Institute, Queen Mary University of London, UK
14:30-14:45Short talk 9
14:45-15:15How does RNA cap regulation direct gene-specific expression?
Victoria Cowling – University of Dundee, UK
15:15-15:30Short talk 10
15:30-16:00Meet the speakers of Session 4
16:00-16:15Break
Session 5 – Emerging concepts
Chair: tba
16:15-16:45Talk title to be announced
Michaela Frye – German Cancer Research Centre (DKFZ), Germany
16:45-17:00Selected short talk 11
17:00-17:30Exploring canonical and non-canonical functions of cancer-linked dihydrouridine synthase enzymes
Wendy Gilbert – Yale University, USA
17:30-18:00Talk title to be announced
Stefanie Kellner-Kaiser, Goethe University Frankfurt, Germany
18:00-18:30Talk title to be announced
V. Narry Kim – Seoul National University, South Korea
18:30-18:45Break
18:45-19:45Panel discussion on emerging therapies
19:45-20:00Closing remarks
20:00-20:30Meet the speakers of Session 5

Practical Information

Registration Fees

Registration Fees (include access to all of the talks, digital poster sessions and online group discussions, and help us cover our costs to run the event. For further information please refer to the FAQ page):

PhD Student/Postdoc€140
Academia/PI€190
Industry€240
EMBL StaffIntranet access

Accredited journalists may be eligible to register for a complimentary registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Aline Schnieder for more information.

Confirmation and Payment

Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee.
Types of payments accepted are international bank transfers and credit card payments.

Abstract submission

Abstract submission deadline: 10 January 2022 (23:59 Europe/Berlin)

Only registered participants are eligible to submit an abstract. We only accept online abstract submissions.

After you have logged in and successfully registered, you will receive an email asking you to submit your abstract.  Click on the link provided and enter your abstract in the text box provided. Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering.

When submitting your abstract you can also apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

Financial Assistance

Financial Fee Waivers

All academic and student registrants are invited to apply for a registration fee waiver, provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO. The registration fee waiver covers the registration sum that you have paid to attend the meeting. Conference participants are not required to pre-pay the registration fee to be selected for a fee waiver for a virtual meeting. If you have already paid the registration fee and are awarded a fee waiver, it will be reimbursed after the meeting.

Childcare Grants

For participants and speakers with childcare responsibilities there is the possibility to apply for a grant, provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO, to offset childcare costs incurred when participating at a virtual event. Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver. Please note that priority will be given to early stage researchers. Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received. Attendance at the event is required in order to be eligible to receive the reimbursement. In order to apply for this grant, you must be registered by the abstract submission deadline.

Application

Applications for financial assistance can be submitted via the submission portal* (for the submission of abstracts for conferences) by completing the Financial Assistance Application Section (underneath the section for entering abstract/motivation letter information). The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference.

For conferences, if you are not submitting an abstract, you can still apply for financial assistance in the submission portal. Take a look at the instructions for applying for financial assistance. Note that priority will be given to those submitting an abstract to present at the conference. In your application you will be asked to answer questions regarding your motivation for applying, and, for registration fee waivers, the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

Selection

The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses. Results will be announced approximately 3 – 4 weeks before the event start date. Selection results do not impact your admission to the meeting. Registration fee waiver selection is based on your current work or study location, your motivation for applying, the reasons for needing financial support and the impact this event will have on your career. Childcare grants are allocated based on career stage, with priority given to early stage researchers.

Further details

Check our list of external funding opportunities and read our information on attending a conference as an event reporter.

For further information about financial assistance please refer to the FAQ page.

Virtual Participation Guidelines

Guidelines

Please do:

  • Use the event-specific hashtag as communicated during the event for any related tweets
  • Tweet unless the speaker specifically says otherwise
  • Be mindful of unpublished data
  • Be respectful in tone and content

Please don’t:

  • Share Slack, live stream or poster session links with others
  • Broadcast the conference to unregistered participants
  • Capture, transmit or redistribute data presented at the meeting unless presenter gives explicit consent
  • Use offensive language in your posts
  • Engage in rudeness or personal attacks

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos. You can find these under ‘resources’ on the conference platform.

How to ask questions

Please use the Q&A function. It is possible to send a direct message to participants, poster presenters, and speakers within the conference platform.

If you have any other questions, you can go to the Help Desk on the conference platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on Central European Time (CET) or Central European Summer Time (CEST) unless otherwise stated. As many virtual participants are attending from around the world, we do our best to accommodate as many time zones as possible when creating the programme. Please take your time zone into consideration when planning your attendance. Remember to set your time zone in your account. 

Virtual event platforms

We are using a virtual event platform for this conference. More information about the platform will be shared ahead of the conference.

Additional Information

Please find additional information including FAQs and terms and conditions on our Information for Participants page.

Sponsors

Sponsorship Opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Warning

EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials. One current scam campaign of which we are aware is conducted using the name ‘Judy Eastman’ (judy@gopcontact.a2hosted.com) and entails approaches to sponsors offering sponsorship opportunities on EMBL’s behalf. Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences, symposia and courses is handled by EMBL directly and is sent from an official EMBL account. EMBL does not work with any external providers on sponsorship acquisition.

Please also note that:

  • EMBL never provides attendee lists for purchase. Any offers of such are fraudulent.
  • EMBL will never call or email you to ask for your credit card details or to request a payment.
  • All payments are on invoice.

Suspicious communications purportedly from, for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring@embl.de.

Date: 9 - 11 Feb 2022

Location: Virtual


Deadline(s):

Abstract submission: 10 Jan 2022

Registration : 2 Feb 2022


Organisers:

  • Michaela Frye
    German Cancer Research Centre (DKFZ), Germany

EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme

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