Chemical biology 2022 – Course and Conference Office

EMBO Workshop

Chemical biology 2022


This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19 terms and conditions.

Conference overview

The conference sets the stage for the dissemination and exchange of new developments in diverse, hot fields within chemical biology. It is the largest and longest standing conference in the field, being a platform for inspiration, collaboration and networking for researchers in academia and industry. We aim to provide the possibility for every chemical biologist to meet and discuss with peers on topics ranging from tool development to biological applications, from computational drug design to synthetic chemistry.

Session topics

  • Drug and target discovery
  • Genetically-encoded biosensors
  • Structure-function relations in chemical biology
  • Chemical tools for biological imaging
  • Metabolism and natural products
  • Synthetic biology and protein design

What past participants say about this conference

“The conference was very well organised with an amazing programme, great speakers and it has proved a valuable source of information! A very challenging and worthwhile experience!” Rosalba Sortino, Institute for Bioengineering of Catalonia

“The EMBO Chemical Biology Workshop 2020 was super! Inspiring talks and very well organised! I had the opportunity to give a short-presentation and got interesting feedback and discussion!” Dr. Ma. Florencia Sanchez, Institute for Biochemistry, University of Frankfurt


Keynote speakers


Tobias Dick

German Cancer Research Center (DKFZ)


Sebastian Essig

Bayer AG


Scientific organisers

Yimon Aye



Claire Deo

EMBL Heidelberg


Kai Johnsson

Max Planck Institute for Medical Research


Edward Lemke

JGU & IMB Mainz


Conference organiser

Lea Hohmann

EMBL Heidelberg



Got something to say? Tweet it! #EMBOChemBio

  • For registered participants, recorded talks will be accessible on demand for 2 weeks after the end of the event, unless indicated otherwise.
  • All times in the programme below are shown as the time in Europe/Berlin.
  • Please find the poster listing here.
Day 1 – Monday 5 September 2022
Time (Europe/ Berlin)Speaker
11:00 – 13:00Registration and Lunch
11:40 – 12:40Pre-conference workshop by Springer Nature (registration required)
13:00 – 13:10Opening remarks
13:10 – 16:45Session 1
Session chair: Arnaud Gautier
13:10 – 13:45Quantitative Chemical Imaging in Immune Cells
Yamuna Krishnan – University of Chicago, USA
13:45 – 14:20ChemoX: a chemogenetic platform of FRET pairs for the rapid
development of biosensors offering tunable wavelengths and
multi-modal readout
Julien Hiblot – Max Planck Institute for Medical Research, Germany
14:20 – 14:35Investigation of the intracellular transport of ether lipids
Kristin Böhlig – MPI-CBG, Germany
14:35 – 15:05Coffee Break
15:05 – 15:40Covalent ligand directed release chemistry
Nir London – Weizmann Institute of Science, Israel
Not available on demand
15:40 – 15:55Phosphotriesterase based chemical-genetic tools for controlled release of chemical reporters
Kesava Phaneendra Cherukuri – Weizmann Institute
of Science, Israel
15:55 – 16:10How small can we go? Miniaturized chemical tags for optical imaging
Fabio De Moliner – The University of Edinburgh, UK
16:10 – 16:4515 Flash talks (2 min/1 slide) selected from abstracts
– Sebastian Andrei – #60
– Sara Bottone – #48
– Francesca Canyelles – #52
– Xinlai Cheng – #56
– Elena De Vita – #62
– Matthew Deen – #64
– Niklas Freund – #70
– Kyohhei Fujita – #72
– Sean Thomas Hennigan – #92
– Kuan-Ting Huang – #94
– Cristina Jimenez Lopez – #98
– Julie Karpenko – #100
– Weifeng Lin – #112
– Ben Mortishire-Smith – #122
– Minh Nguyen Trung – #126

Not available on demand
16:45 – 18:30Poster session 1 (even numbers)
18:30 – 19:30Keynote Session
Dorothee Kern – Brandeis University, USA
19:30 – 21:00Dinner
Day 2 – Tuesday 6 September 2022
Time (Europe/ Berlin) Speaker
09:00 – 12:15Session 2
Session chair: Yamuna Krishnan
09:00 –09:35Fluorescent chemogenetic reporters to spy on cells
Arnaud Gautier – Sorbonne University, France
09:35 – 10:10Discovery of a druggable copper signaling pathway that drives
cell plasticity and inflammation
Raphael Rodriguez – Institut Curie, France
10:10 – 10:25RNA methylation and postsynthetic labelling catalyzed by ribozymes
Claudia Höbartner – Julius-Maximilians-University of Würzburg, Germany
Not available on demand
10:25 – 10:40The development and characterisation of a novel antimalarial
class targeting a putative mitochondrial carrier protein
Brodie Bailey – Walter and Eliza Hall Institute, Australia
10:40 – 11:10Coffee break
11:10 – 11:45Mechanisms of thiol based redox signaling
Tobias Dick – DKFZ, Germany
Not available on demand
11:45 – 12:00Chemoproteomic target deconvolution of metallo-enzyme drugs
Severin Lechner – Technical University of Munich, German
12:00 – 12:15Macrocyclic peptides that display potent allosteric inhibition of O-GlcNAc transferase and their use as chemical tools
Jil Busmann – Simon Fraser University, Canada
Not available on demand
12:15 – 12:30Function-guided proximity mapping in C. elegans directed by local electrophile responsivity
Jinmin Liu – EPFL, Switzerland
Not available on demand
12:30 – 14:00Lunch
Session 3
Session chair: Raphael Rodriguez
14:00 – 14:35Chemical biology to understand and harness the innate immune STING pathway
Lingyin Li – Stanford University, USA
14:35 – 15:10Towards a Chemical Biology platform for the systematic discovery and evaluation of novel covalent chemistry
Sebastian Essig – Bayer, Germany
Not available on demand
15:10 – 15:25Anticipatory design of SARSCoV2 protease inhibitors for antiviral resistance mutants
Michael Westberg – Stanford and Aarhus University, USA
Not available on demand
15:25 – 15:40Reconstitution of S. aureus agr quorum sensing reveals a direct role for the integral membrane protease MroQ in pheromone biosynthesis
Steven Bodine – Princeton University, USA
15:40 – 16:10Coffee break
16:10 – 16:45Structural basis of FANCD2 deubiquitination by USP1-UAF1
Helen Walden – University of Glasgow, UK
16:45 – 17:00Bacterial Biosensors that can compute
Ramez Daniel – Technion – Israel Institute of Technology, Israel
17:00 – 17:207 Flash talks (2 min/1 slide) selected from abstracts
– Nüket Bilgen – #47
– Mohammad Eid – #67
– Malte Gersch – #81
– Ori Green – #79
– Stephan Hacker – #171
– Wouter Kallemeijn – #99
– Michelle Hundevad Rasmussen – #137

Not available on demand
17:20 – 18:00Meet the speakers session and pre-dinner drinks
18:00 – 19:45Dinner in EMBL Canteen
19:45 – 21:30Poster session 2 (odd numbers)
Day 3 – Wednesday 7 September 2022
Time (Europe/ Berlin) Speaker
Session 4
09:00 – 09:35The roles of lipids in cell biology
Ulrike Eggert – King’s College, UK
Not available on demand
09:35 – 10:10Deciphering the human microbiome with chemistry
Emily Balskus – Harvard University, USA
10:10 – 10:45Computational design of enzyme repertoires
Sarel Fleishman – Weizmann Institute of Science, Israel
10:45 – 11:15Coffee Break and Meet the speakers
11:15 – 11:30CaProLa: a Ca2+ dependent protein labeling tool for neuronal activity integration in multi-color
Magnus Huppertz – Max-Planck-Institute for Medical Research, Germany
11:30 – 12:05Illuminating protein-protein interaction networks in disease through chemical biology
Gabriela Chiosis – Sloan Kettering Institute, USA
12:05 – 12:20Glow-in-the-dark diagnostics using bioluminescent sensor proteins
Eva van Aalen – Eindhoven University of Technology, Netherlands
12:20 – 12:35Biological hydropersulfides suppress lipid peroxidation and ferroptosis by scavenging free radicals
Uladzimir Barayeu – German Cancer Research Center (DKFZ), Germany
12:35 – 13:10Chemical medicine: New cancer medical technology based on live fluorescence imaging of each patient
Yasuteru Urano – University of Tokyo, Japan
13:10 – 14:40Lunch
14:30 – 15:00Meet the editors & further networking
– Kai Johnsson (JACS)
– Yimon Aye (ACS Chemical Biology)
– Katja Glatz (Chemistry – A European Journal, ChemBioChem and ChemistrySelect)
– Edward Lemke (Journal of Molecular Biology)
– Sarah Whitbread (RSC Chemical Biology)
– Laura Woodward-Heni (Angewandte Chemie)
Session 5
Session chair: Pablo Rivera Fuentes
15:00 – 16:00Keynote lecture: Playing with the molecules of life
Peter Schultz – The Scripps Research Institute, USA (remotely)
Not available on demand
16:00 – 16:15Photo-immobilisation for target profiling of natural products and cofactors
Polina Prokofeva- Technical University of Munich, Germany
16:15 – 16:30The choline metabolite-interacting proteome of mammalian cells: discovery and significance
Aditi Dixit – Indian Institute of Science Education and Research (IISER), Pune, India
16:30 – 16:508 Flash talks (2 min/1 slide) selected from abstracts

– Robert B. Quast – #134
– Efrat Resnick – #139
– Maria Florencia Sánchez – #144
– Cong Tang – #155
– Alexandra Teslenko – #156
– Oliver Thorn-Seshold – #172
– Janelle Tobias – #158
– Kaveri Vaidya – #162

Not available on demand
16:50 –17:20Meet the speakers & coffee break
17:20 – 18:50Poster session 3 (all)
18:50 – 21:15Dinner
21:15 – 22:30After dinner drinks and Live Jazz music
Day 4 – Thursday 8 September 2022
Time (Europe/ Berlin) Speaker
09:00 – 12:30Session 6
Session Chair: Edward Lemke
09:00 – 09:35Expanding the chemical biology toolbox for mammalian cells
Simon Elsässer – Karolinska Institutet, Sweden
09:35 – 10:10Chemical tools to study redox biology
Pablo Rivera-Fuentes – University of Zurich, Switzerland
Not available on demand
10:10 – 10:25Deciphering chromatin ubiquitylation involving RNF168 using chemical biology
Pauline Franz – Ecole Polytechnique Fédérale de Lausanne (EPFL), Switzerland
10:25 – 10:40Exploring the scope of JmjC-KDMs catalysed N-methyl arginine demethylase activity
Joanna Bonnici – Newcastle University, University of Oxford, UK
10:40 – 11:10Coffee Break and Meet the speakers
11:10 – 11:25Engineering of a pH-switchable generic antibody-blocking protein
Lieuwe Biewenga – Technische Universiteit Eindhoven, The Netherlands
11:25 – 11:40A method for conditional control of cellular protein stability using an excisable degron tag
Yuki Utsugi – University of Tsukuba, Japan
11:40 – 12:15Single-molecule chemistry in a protein nanoreactor
Hagan Bayley – University of Oxford, UK
Not available on demand
12:15 – 12:30Closing Remarks and Poster Prize
12:30 – 13:00Packed Lunch and departure
13:00Optional: Bus to Frankfurt Airport (Terminal 1) – Tickets can be purchased on-site for 25 EUR

Practical information

Registration fees and abstract submission

On-site registration fees include admission, conference materials, COVID-19 safety measures, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.

Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.

On-site Academia€ 450
On-site PhD Student€ 350
On-site Industry€ 700
Virtual Academia€ 175
Virtual PhD Student€ 125
Virtual Industry€ 225

NO visa support letters will be issued until payment of the registration fee is confirmed.

Accredited journalists may be eligible to register for complimentary press registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Lea Hohmann for more information. Please note that we do not offer complimentary registrations for editors of scientific journals.

Confirmation and payment

Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.

On-site participants: Types of payments accepted are international bank transfers and credit card payments.

Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact events@embl.de for details.

Abstract submission

Only registered participants attending the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.

After you have logged in and successfully registered, you will receive an email asking you to submit your abstract.  Click on the link provided and enter your abstract in the text box provided. Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering. The same login credentials are used for both processes.

Please note:

Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase.

Authors and affiliations: Please fill in the author’s details as requested in the online form. The compulsory details are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email. Mark only one author as the role of First author and please don’t forget to indicate who will be presenting. The order of the authors will be listed as follows: First Author, Co-First Author (alphabetically if multiple), co-author(s) (in the order added by the submitter).

Optional: if you would like to upload an image in conjunction with your abstract please note:

  • We only accept one image per abstract
  • We only accept png or jpeg formats
  • The image should have a printable resolution of minimum 300 dpi
  • The maximum size of the image is 10 cm (1180 px) wide by 8 cm (945 px) high
    (Any images exceeding these dimensions will be automatically excluded)
  • The image will be placed beneath your abstract text which needs to be limited to approximately 1200 characters; so that both image and text fit on one page of the abstract book.

Presentation types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.

Please check our FAQs pages for further information on how to submit an abstract.

Financial assistance

Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants. Availability is limited to participants attending on-site events in Heidelberg and will be indicated during the abstract or motivation letter submission process.

Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.

Registration fee waiver

The fee waiver will cover the registration sum that you have paid to attend the course or conference.

Travel grant

The travel grant will cover the cost of travel (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:

– up to €400 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from within Europe.
– up to €1000 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from outside Europe.
– up to €500 for any participant travelling to an EMBO Practical Course or EMBO Workshop.
– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop.

*Registration fees are only covered for EMBO Practical Courses or EMBO Workshops

The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.


You may apply for financial assistance when submitting your motivation letter for courses, and abstract for conferences. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.

For the Boehringer Ingelheim Fonds Travel Grant, there is a pre-application question during the motivation letter submission process, and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation.


The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process. Results will be announced approximately 6-8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on your current work or study location, the reasons for needing financial support and the impact this event will have on your career.


Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.

Further details

View our list of external funding opportunities and information on attending a conference as an event reporter.

For further information about financial assistance please refer to the FAQ page.

Accommodation and shuttles

Accommodation is not included in the conference registration fee.

As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.

The hotels below have rooms on hold for participants until 4 August 2022, in some cases at special rates. Please quote the booking code CHB22-01 and confirm the exact price of the room with the hotel directly.

Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg City
Hotel Bayrischer Hof ISG Hotel Staycity Aparthotel Heidelberg
B&B HotelLeonardo Hotel Heidelberg City CentreSteffi’s Hostel Heidelberg
Exzellenz Hotel & Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten Heidelberg
Hotel Holländer Hof Hotel Monpti

Conference shuttle buses

Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.

Download the bus schedule here.

The bus stops for this conference are:

  • Star Inn Staycity Aparthotel (close to B&B Hotel and Main Train Station)
  • Kurfürsten-Anlage (opposite Main Train Station)
  • Premier Inn Hotel, Kurfürsten-Anlage 23
  • Leonardo Hotel City Centre (Bergheimer Strasse)
  • Neckarmünzplatz
  • Peterskirche
  • ISG Hotel

View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.

Further details

Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.

Virtual participation

What’s included?

  • Access to all the livestreamed talks
  • Video library of the recorded talks during and after the event
  • Facility to submit questions

Please note that only on-site participants are able to submit abstracts and participate in the poster sessions.

Event platform

We are using an event platform for this conference. More information about the platform will be shared ahead of the conference.


  • Do not broadcast the conference to unregistered participants.
  • You are encouraged to tweet and post about the event. Tweet unless the speaker specifically says otherwise, but be mindful of unpublished data. 
  • Please do not capture, transmit or redistribute data presented at the meeting.

Additional information can be found in our Code of Conduct.

Health and well-being

It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.

How to ask questions

Please use the Q&A function in the event platform.

If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk. 

Time zone

The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. Please take your time zone into consideration when planning your attendance.

Additional information

Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.

COVID-19 related questions

COVID-19 information for on-site events at EMBL Heidelberg can be found in our COVID-19 FAQs.


Silver sponsor


Bronze sponsor


Event sponsor


Media partners

ACS Chemical Biology

Angewandte Chemie, a Wiley journal

ChemBioChem, a Wiley journal

EMBO reports, an EMBO Press journal

International Union of Biochemistry and Molecular Biology

Journal of the American Chemical Society, a journal of the American Chemical Society

Open Biology, a Royal Society journal

RSC Chemical Biology, Royal Society of Chemistry


Sponsorship opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.

Pre-conference workshop

Industry webinar will be hosted by our sponsor Springer Nature prior to the EMBO Workshop: Chemical biology 2022

on Monday, 5 September, 11:40 – 12:40

Participation in this workshop is free of charge for registered conference attendees. The number of available places is limited (first come, first served). All registered conference attendees will receive an email with a registration link.


Using Protocols and Methods to combat the reproducibility crisis-leveraging Springer Nature Experiments

Speaker: Anja Riedel, Associate Product Manager, Springer Nature

Reproducing, and thereby building on previous research poses a major challenge within the life sciences [1]. More than 40% of respondents named the lack of available information about methods as a major contributor to the irreproducibility of published experiments [2]. In this interactive workshop, we will explore the role of protocols and methods to combat the reproducibility crisis and showcase how the Springer Nature Experiments platform can help scientists to find protocols and methods content in order to achieve more reproducible results. Springer Nature Experiments supports researchers in navigating the leading Springer Protocols & Methods portfolio, which includes the publications Springer Protocols, Nature Protocols, Nature Methods, and Nature Reviews Methods Primers.

[1] Borges, R.M. Reproducibility and replicability in science: A Sisyphean task. J Biosci 47, 15 (2022). https://doi.org/10.1007/s12038-022-00259-6

[2] Baker, M. 1,500 scientists lift the lid on reproducibility. Nature 533, 452–454 (2016). https://doi.org/10.1038/533452a

Date: 5 - 8 Sep 2022

Location: EMBL Heidelberg and Virtual

Venue: EMBL Advanced Training Centre


Abstract submission: Closed

Registration (On-site): Closed

Registration (Virtual): Closed


  • Yimon Aye
    Ecole Polytechnique Federale de Lausanne, Switzerland
    • Claire Deo
      EMBL Heidelberg, Germany