Development

How single cells give rise to complex organisms

All the essential information on how a whole multicellular organism develops from a single cell is stored in that organism's genome and epigenome. Thousands of genes are switched on and off in a precisely coordinated manner.

A four-day-old mouse embryo
A four-day-old mouse embryo before it embeds itself in the womb. The cells that will make the connection to the womb are marked in blue. The cells that will give rise to the embryo are marked in orange, and the cells’ membranes are labeled in purple.

This enables individual cells to specialise in particular tasks and to arrange themselves into tissues and organs in the right locations. The developmental process is also influenced by environmental factors, such as the availability of nutrients.

Scientists at EMBL investigate the processes associated with embryo and organism development. They try to understand how embryos transition from a ball of identical cells to structured organisms with highly specialised tissues. The influence of mechanical stimuli and environmental factors on development are also investigated. EMBL scientists try to understand how biological rhythms create waves of activity of genes or signalling molecules, which helps to establish regular structures and tells organs where to form. Alongside traditional lab methods, bioinformatics approaches are also used to explore the processes of development.


EMBL units researching development

Developmental biology

Scientists in the Developmental biology unit seek to understand the fundamental principles that govern multicellular development.

Genome biology

The Genome biology unit uses and develops cutting-edge methods to study how the information in our genome is regulated, processed, and utilised, and how its alteration leads to disease.

Tissue biology and disease modelling

Scientists at EMBL Barcelona use advanced technologies to observe, manipulate, and model how changes in genes percolate through cells, tissues, and organs, in health and disease.

View all EMBL research units


Scientific Officer - Advanced Light Microscopy

Technology in EMBL Heidelberg

The Advanced Light Microscopy Facility at EMBL Heidelberg (ALMF) offers a collection of state of the art equipment and image processing tools to support in-house scientists and visitors in using light microscopy methods for their research. Incollaboration with other Core Facilities the ALMF also off...

Closes on 12th May. Posted 13th April 2026

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Data Architect / Knowledge Engineer – Euro-BioImaging (AI4Access)

Technology in EMBL Heidelberg

Euro-BioImaging ERIC is a European research infrastructure providing life scientists open access to advanced imaging technologies, expertise, training and data services through almost 300 imaging facilities distributed among 40 Nodes across Europe. The Euro-BioImaging Hub is distributed across three...

Closes on 16th May. Posted 13th April 2026

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Postdoctoral Researcher in Computational Genetics

Science, research and training in EMBL Heidelberg

The research group of Oliver Stegle looks for a postdoctoral researcher to join a collaborative project with GSK with the goal to apply computational methods to investigate the effects of rare variants on human traits and single-cell readouts.  Our research group is pioneering computational methods...

Closes on 1st May. Posted 30th March 2026

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Postdoctoral Fellow in AI Agents for Science

Science, research and training in Rome, Italy

Your groupFabio Petroni’s lab - EMBL Rome.Our mission is to build AI systems that act as cognitive members of a scientific laboratory. We design and evaluate agentic AI systems that collaborate with researchers across the full discovery cycle: literature analysis, hypothesis generation, experimental...

Closes on 1st May. Posted 25th March 2026

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From microscopy to mycology, from development to disease modelling, EMBL researchers cover a wide range of topics in the biological sciences.