Development

How single cells give rise to complex organisms

All the essential information on how a whole multicellular organism develops from a single cell is stored in that organism's genome and epigenome. Thousands of genes are switched on and off in a precisely coordinated manner.

A four-day-old mouse embryo
A four-day-old mouse embryo before it embeds itself in the womb. The cells that will make the connection to the womb are marked in blue. The cells that will give rise to the embryo are marked in orange, and the cells’ membranes are labeled in purple.

This enables individual cells to specialise in particular tasks and to arrange themselves into tissues and organs in the right locations. The developmental process is also influenced by environmental factors, such as the availability of nutrients.

Scientists at EMBL investigate the processes associated with embryo and organism development. They try to understand how embryos transition from a ball of identical cells to structured organisms with highly specialised tissues. The influence of mechanical stimuli and environmental factors on development are also investigated. EMBL scientists try to understand how biological rhythms create waves of activity of genes or signalling molecules, which helps to establish regular structures and tells organs where to form. Alongside traditional lab methods, bioinformatics approaches are also used to explore the processes of development.


EMBL units researching development

Developmental biology

Scientists in the Developmental biology unit seek to understand the fundamental principles that govern multicellular development.

Genome biology

The Genome biology unit uses and develops cutting-edge methods to study how the information in our genome is regulated, processed, and utilised, and how its alteration leads to disease.

Tissue biology and disease modelling

Scientists at EMBL Barcelona use advanced technologies to observe, manipulate, and model how changes in genes percolate through cells, tissues, and organs, in health and disease.

View all EMBL research units


Ensembl Microbes Bioinformatician

Technology in EMBL-EBI Hinxton

Role Summary / Context About the TeamWe are seeking a skilled bioinformatician who is enthusiastic about developing and maintaining high-quality genome resources for microbial research communities to join the Ensembl Microbes team.As part of the Ensembl project, Ensembl Microbes provides access to b...

Closes on 11th November. Posted 28th October 2026

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Scientific Developer (Chemical Biology Resources)

Technology in EMBL-EBI Hinxton

We are looking for a highly motivated Scientific Developer to join the Chemical Biology Resources team at the European Bioinformatics Institute (EMBL-EBI), located on the Wellcome Genome Campus near Cambridge, UK. This is a 13-month fixed-term position offered as maternity cover. The Chemical Biolog...

Closes on 13th November. Posted 28th October 2026

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Laboratory Animal Technician

Science, research and training in EMBL Heidelberg

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy). Responsi...

Closes on 18th November. Posted 20th October 2026

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Bioinformatician – Structural Proteomics & Integrative Modelling

Technology in EMBL-EBI Hinxton

About the team/job We are seeking a Bioinformatician with expertise in structural biology, proteomics and integrative/hybrid structure modelling to join the Velankar team at the European Bioinformatics Institute (EMBL-EBI).The Protein Data Bank in Europe (PDBe) team develops essential macromolecular...

Closes on 4th November. Posted 13th October 2026

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From microscopy to mycology, from development to disease modelling, EMBL researchers cover a wide range of topics in the biological sciences.