Development

How single cells give rise to complex organisms

All the essential information on how a whole multicellular organism develops from a single cell is stored in that organism's genome and epigenome. Thousands of genes are switched on and off in a precisely coordinated manner.

A four-day-old mouse embryo
A four-day-old mouse embryo before it embeds itself in the womb. The cells that will make the connection to the womb are marked in blue. The cells that will give rise to the embryo are marked in orange, and the cells’ membranes are labeled in purple.

This enables individual cells to specialise in particular tasks and to arrange themselves into tissues and organs in the right locations. The developmental process is also influenced by environmental factors, such as the availability of nutrients.

Scientists at EMBL investigate the processes associated with embryo and organism development. They try to understand how embryos transition from a ball of identical cells to structured organisms with highly specialised tissues. The influence of mechanical stimuli and environmental factors on development are also investigated. EMBL scientists try to understand how biological rhythms create waves of activity of genes or signalling molecules, which helps to establish regular structures and tells organs where to form. Alongside traditional lab methods, bioinformatics approaches are also used to explore the processes of development.


EMBL units researching development

Developmental biology

Scientists in the Developmental biology unit seek to understand the fundamental principles that govern multicellular development.

Genome biology

The Genome biology unit uses and develops cutting-edge methods to study how the information in our genome is regulated, processed, and utilised, and how its alteration leads to disease.

Tissue biology and disease modelling

Scientists at EMBL Barcelona use advanced technologies to observe, manipulate, and model how changes in genes percolate through cells, tissues, and organs, in health and disease.

View all EMBL research units


Protein Function Development Team Leader

Technology in EMBL-EBI Hinxton

Overview We are seeking an exceptional candidate for the EMBL-EBI Faculty role of Protein Function Development Team Leader, to be responsible for leading the engineering and bioinformatics infrastructure that underpins one of the most important resources in the life sciences, Uniprot.UniProt is the...

Closes on 16th July. Posted 10th June 2026

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Data Engineer

Technology in EMBL-EBI Hinxton

About the TeamThe Velankar team maintains macromolecular structure databases that form essential resources for biologists and other life scientists worldwide. PDBe is a founding partner of the Worldwide Protein Data Bank organisation, which maintains the global archive of 3D structural data on macro...

Closes on 29th June. Posted 8th June 2026

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InterPro/Pfam Software Project Leader

Technology in EMBL-EBI Hinxton

About the teamIn your role, you will lead the software development team responsible for the Pfam and InterPro databases. These are two of the world’s most widely used protein family and domain annotation resources, serving thousands of users globally. Reporting to the Head of the Protein Families Gr...

Closes on 6th July. Posted 8th June 2026

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Photographer

Technology in EMBL Heidelberg

The photographer will join a team of eight, providing modern photographic, video and conference services in a large international scientific research environment.Your role As a member of the Photographic Section, the post holder will be expected to undertake digital imaging and processing, studio an...

Closes on 18th June. Posted 3rd June 2026

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From microscopy to mycology, from development to disease modelling, EMBL researchers cover a wide range of topics in the biological sciences.