Development

How single cells give rise to complex organisms

All the essential information on how a whole multicellular organism develops from a single cell is stored in that organism's genome and epigenome. Thousands of genes are switched on and off in a precisely coordinated manner.

A four-day-old mouse embryo
A four-day-old mouse embryo before it embeds itself in the womb. The cells that will make the connection to the womb are marked in blue. The cells that will give rise to the embryo are marked in orange, and the cells’ membranes are labeled in purple.

This enables individual cells to specialise in particular tasks and to arrange themselves into tissues and organs in the right locations. The developmental process is also influenced by environmental factors, such as the availability of nutrients.

Scientists at EMBL investigate the processes associated with embryo and organism development. They try to understand how embryos transition from a ball of identical cells to structured organisms with highly specialised tissues. The influence of mechanical stimuli and environmental factors on development are also investigated. EMBL scientists try to understand how biological rhythms create waves of activity of genes or signalling molecules, which helps to establish regular structures and tells organs where to form. Alongside traditional lab methods, bioinformatics approaches are also used to explore the processes of development.


EMBL units researching development

Developmental biology

Scientists in the Developmental biology unit seek to understand the fundamental principles that govern multicellular development.

Genome biology

The Genome biology unit uses and develops cutting-edge methods to study how the information in our genome is regulated, processed, and utilised, and how its alteration leads to disease.

Tissue biology and disease modelling

Scientists at EMBL Barcelona use advanced technologies to observe, manipulate, and model how changes in genes percolate through cells, tissues, and organs, in health and disease.

View all EMBL research units


Laboratory Officer

Technology in EMBL Heidelberg

 The Quail group at EMBL Heidelberg is looking for a highly motivated biochemist or biophysicist to join us as a Laboratory Officer. We combine single-molecule biophysics, in vitro biochemistry, quantitative imaging, and cell biology to study how proteins and enzymes collectively organize the genome...

Closes on 29th October. Posted 8th October 2026

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Scientific Officer - Metabolomics Core Facility

Technology in EMBL Heidelberg

The European Molecular Biology Laboratory (EMBL) is a top-ranked scientific research organization aimed to explore the secrets of life. With over 1800 employees across six European sites, EMBL integrates research groups and core facilities to foster world-class science.The Metabolomics Core Facility...

Closes on 13th October. Posted 29th September 2026

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Scientific Developer (Chemical Biology Resources)

Technology in EMBL-EBI Hinxton

About the team/jobSafety and toxicology concerns remain one of the most persistent challenges in drug discovery. This is an exciting opportunity to join a multi-disciplinary team on a project to develop a comprehensive open source side effect resource for the scientific and pharmaceutical community,...

Closes on 12th October. Posted 14th September 2026

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Plant Genomics and Variation Team Leader

Technology in EMBL-EBI Hinxton

Are you ready to shape the future of crop genomics, invertebrate genomics and genetic variation resources at one of the world's leading bioinformatics institutes? We are seeking an internationally minded, community-focused Team Leader with expertise in genomics, particularly crop plants and their as...

Closes on 12th October. Posted 2nd September 2026

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From microscopy to mycology, from development to disease modelling, EMBL researchers cover a wide range of topics in the biological sciences.