EMBL Seminars

EMBL delivers world-class courses, conferences and workshops at the forefront of molecular life science and its applications.

Browse upcoming events below, or learn more about training at EMBL.

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17 March 2022, 16:00

Short-range quorum sensing controls horizontal gene transfer at micron scale in bacterial communities

17 March 20222022Symbnet seriesEMBL Heidelberg

Speaker: Jordi Van Gestel

University California, San Francisco (UCSF), US

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


17 March 2022, 16:30

The maintenance of avirulence in Toxoplasma gondii.

17 March 20222022Symbnet seriesEMBL Heidelberg

Speaker: Jonathan Howard

Host-Pathogen Co-evolution Lab, FCG-IGC, Portugal

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


18 March 2022, 13:00

To be announced

18 March 20222022Hamburg SpeakerEMBL Hamburg

Speaker: Maya Topf

CSSB, Hamburg

Host: Maria Garcia

Place: via Zoom VC

Hamburg Speaker

EMBL Hamburg


25 March 2022, 11:00

The role of the medium in modulating multicomponent phase behaviour of associating polymers

25 March 20222022Seminar given by an external postdoc EMBL Heidelberg

https://embl-org.zoom.us/j/96838401413?pwd=bGJSUlpKNUhSb0toZFFCRlhhWVdV… Meeting ID: 968 3840 1413 Passcode: BlueSCB https://embl-org.zoom.us/j/96838401413?pwd=bGJSUlpKNUhSb0toZFFCRlhhWVdV… Meeting ID: 968 3840 1413 Passcode: BlueSCB

Speaker: Jasper Michels

Max Planck Institute for Polymer Research Mainz

Host: Mahamid Lab / Mukthi Iyer

Place: Small Operon

Seminar given by an external postdoc

EMBL Heidelberg


25 March 2022, 15:00

Tissue flow during zebrafish development and its role in left-right asymmetry

25 March 20222022Seminar given by an external postdoc EMBL Heidelberg

The establishment of left-right (LR) asymmetry during embryonic development is vital to the proper formation of internal organs in vertebrates. In the zebrafish embryo, Kupffer’s vesicle (KV) is a transient organ that acts as the LR organizer. For this LR organization to occur, KV cells must change shape along the anterior-posterior (AP) axis as the KV travels through the tailbud tissue, resulting in an asymmetric distribution of cells. However, the mechanisms that drive these KV cell shape changes remain poorly understood. The establishment of left-right (LR) asymmetry during embryonic development is vital to the proper formation of internal organs in vertebrates. In the zebrafish embryo, Kupffer’s vesicle (KV) is a transient organ that acts as the LR organizer. For this LR organization to occur, KV cells must change shape along the anterior-posterior (AP) axis as the KV travels through the tailbud tissue, resulting in an asymmetric distribution of cells. However, the mechanisms that drive these KV cell shape changes remain poorly understood. 3D vertex-like modeling results and in vivo particle image velocimetry (PIV) analysis suggest that drag forces exerted by the tailbud tissue flow can change KV cell shapes. As a continuation of these findings, we recently ablated the embryo’s notochord to disturb the notochord’s convergent extension, which seems to affect KV movement. This work was supported by NIH...

Speaker: Paula Sanematsu

Syracuse University, New York

Place: via Zoom VC

Seminar given by an external postdoc

EMBL Heidelberg


1 April 2022, 10:00

How fly neurons compute the direction of visual motion

1 April 20222022EMBL Distinguished Visitor LectureEMBL Rome

Detecting the direction of image motion is important for visual navigation, predator avoidance and prey capture, and thus essential for the survival of all animals that have eyes. However, the direction of motion is not explicitly represented at the level of the photoreceptors: it rather needs to be computed by subsequent neural circuits, involving a comparison of the signals from neighboring photoreceptors over time. The exact nature of this process represents a classic example of neural computation and has been a longstanding question in the field. Detecting the direction of image motion is important for visual navigation, predator avoidance and prey capture, and thus essential for the survival of all animals that have eyes. However, the direction of motion is not explicitly represented at the level of the photoreceptors: it rather needs to be computed by subsequent neural circuits, involving a comparison of the signals from neighboring photoreceptors over time. The exact nature of this process represents a classic example of neural computation and has been a longstanding question in the field. Only recently, much progress has been made in the fruit fly Drosophila by genetically targeting individual neuron types to block, activate or record from them. Our results obtained this way demonstrate that the local direction of motion is computed in two parallel ON and OFF pathways. Within each pathway, a retinotopic array of four...

Speaker: Alexander Borst

Max-Planck-Institute of Neurobiology, Martinsried

Host: Hiroki Asari

Place: Conf Room/Building 14

EMBL Distinguished Visitor Lecture

EMBL Rome


5 April 2022, 09:30

Mobile Laboratories at Fraunhofer company (to be announced)

5 April 20222022Planetary Biology LecturesVirtual

Speaker: Marina Gebert

Head of Marine Biotechnology Department, FRAUNHOFER EMB

Host: Rainer Pepperkok

Place: Virtual

Planetary Biology Lectures

Virtual


8 April 2022, 11:00

Dissecting the regulatory landscape of the developing cerebral cortex using single-cell epigenomics

8 April 20222022External Faculty SpeakerEMBL Rome

Understanding how different epigenetic layers are coordinated to facilitate robust lineage decisions during development is one of the fundamental questions in regulatory genomics. Using single-cell epigenomics coupled with cell-type specific high-throughput mapping of enhancer activity, DNA methylation and the 3D genome landscape in vivo, we dissected how the epigenome is rewired during cortical development. Understanding how different epigenetic layers are coordinated to facilitate robust lineage decisions during development is one of the fundamental questions in regulatory genomics. Using single-cell epigenomics coupled with cell-type specific high-throughput mapping of enhancer activity, DNA methylation and the 3D genome landscape in vivo, we dissected how the epigenome is rewired during cortical development. We identified and functionally validated key transcription factors such as Neurog2 which underlie regulatory dynamics and coordinate rewiring across multiple epigenetic layers to ensure robust lineage specification. This work showcases the power of high-throughput integrative genomics to unravel the molecular rules of cell fate decisions in the brain and more broadly, how to apply them to evolution and disease.

Speaker: Boyan Bonev

Helmholtz Zentrum München Munich

Host: Marzia Munafo` & Rahul Sureka

Place: Conf Room/Building 14

External Faculty Speaker

EMBL Rome



13 April 2022, 16:00

“RNA genomics technologies: Accelerating RNA research”

13 April 20222022Company RepresentativeEMBL Heidelberg

Novel RNA genomics technologies go beyond traditional RNA-Seq and have the potential to illuminate structural and regulatory aspects of RNA as well as the RNA interactome. This seminar will detail NGS-based strategies to investigate RNA interactions with RNA binding proteins, RNA modifications such as m6A, alternative transcription start site (TSS) and polyadenylation site (PAS) usage as well as the microRNA-mRNA interactome. Novel RNA genomics technologies go beyond traditional RNA-Seq and have the potential to illuminate structural and regulatory aspects of RNA as well as the RNA interactome. This seminar will detail NGS-based strategies to investigate RNA interactions with RNA binding proteins, RNA modifications such as m6A, alternative transcription start site (TSS) and polyadenylation site (PAS) usage as well as the microRNA-mRNA interactome.

Speaker: Karen B. Chapman

Eclipse Bioinnovations, Inc.

Host: Matthias Hentze

Place: Virtual seminar

Company Representative

EMBL Heidelberg


20 April 2022, 16:00

How personalised is your immune repertoire

20 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Aleksandra Walczak

Ecole Normale Supérieure

Host: Alexander Aulehla for Theory@EMBL

Place: Large Operon

Theory@EMBL seminar

EMBL Heidelberg


21 April 2022, 16:00

Resource competition regulates the cnidarian-algal symbiosis

21 April 20222022Symbnet seriesEMBL Heidelberg

Speaker: Nils Raedecker

Laboratory for Biological Geochemistry, EPFL-UNIL, Switzerland

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


21 April 2022, 16:00

Protein Pattern Formation

21 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Erwin Frey

LMU Munich

Host: Alexander Aulehla for Theory@EMBL

Place: Large Operon

Theory@EMBL seminar

EMBL Heidelberg


21 April 2022, 16:30

Optical Cell Biology Lab, FCG-IGC, Portugal

21 April 20222022Symbnet seriesEMBL Heidelberg

Speaker: Ricardo Henriques

Optical Cell Biology Lab, FCG-IGC, Portugal

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


22 April 2022, 11:00

Human ecosystems: Harnessing epigenetic (and genetic) variation to understand and predict disease

22 April 20222022External Faculty SpeakerEMBL Rome

The epigenome is malleable and responsive to environmental influences, providing a potential mechanism through which our physical, social and biological experiences can alter gene function and ultimately disease risk and disease course. The epigenome is malleable and responsive to environmental influences, providing a potential mechanism through which our physical, social and biological experiences can alter gene function and ultimately disease risk and disease course. This talk will present findings from molecular epidemiological investigations looking into the influence of the environment on the epigenome (DNA methylation) in human populations. Such methods are potentially complementary to model-based systems and experimental approaches that have been used to interrogate the role of the epigenome in cellular processes and have relevance to the Human Ecosystems theme of the new EMBL Molecules to Ecosystems Programme (2022-2026).

Speaker: Caroline Relton

Bristol Medical School University of Bristol, Bristol

Host: Cornelius Gross & Helen Parkinson

Place: Conf Room/Building 14

External Faculty Speaker

EMBL Rome



22 April 2022, 16:00

Reality and probability: from atoms to bacteria and the Earth climate

22 April 20222022External Faculty SpeakerEMBL Heidelberg

*** Meeting ID: 910 5345 7980 / Passcode: 449594*** *** Meeting ID: 910 5345 7980 / Passcode: 449594*** Abstract: Probability is arguably the most effective mathematical tool that all sciences use. However, probability is not reality, and one should be aware of the relations between them, in order to avoid errors, and actually develop useful predictive theories. In this lecture, I will invite the audience and myself to ponder the matter, illustrating various notions probability and giving examples of how statistical physics understands thermodynamic phenomena. I will then discuss success and failures in the use of probabilities in Physics, and will conclude mentioning some applications of biological and geophysical interest.

Speaker: Lamberto Rondoni

Polytechnic University of Turin

Host: Anna Erzberger

Place: Large Operon

External Faculty Speaker

EMBL Heidelberg


23 April 2022, 16:00

Fluid flows shaping morphology

23 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Karen Alim

Technical University Munich

Host: Alexander Aulehla for Theory@EMBL

Place: Large Operon

Theory@EMBL seminar

EMBL Heidelberg


25 April 2022, 16:00

Robust DNA replication initiation from coupled homeostatic mechanisms

25 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Pieter Rein ten Wolde

AMOLF

Host: Alexander Aulehla for Theory@EMBL

Place: Large Operon

Theory@EMBL seminar

EMBL Heidelberg


26 April 2022, 16:00

Human Impacts by the Numbers

26 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Rachel Banks

Caltech

Host: Alexander Aulehla

Place: Large Operon

Theory@EMBL seminar

EMBL Heidelberg


27 April 2022, 16:00

Speed limits to the evolution of regulatory sequence

27 April 20222022Theory@EMBL seminarEMBL Heidelberg

Speaker: Gasper Tkacik

IST

Host: Alexander Aulehla for Theory@EMBL

Place: all EMBL HD

Theory@EMBL seminar

EMBL Heidelberg


28 April 2022, 10:00

Understanding the global biogeography and ecology of soil microbial communities in a warmer and more arid planet.

28 April 20222022Planetary Biology LecturesVirtual

Join Zoom Meeting https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNr… Meeting ID: 936 0817 9765 Passcode: PBLS Join Zoom Meeting https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNr… Meeting ID: 936 0817 9765 Passcode: PBLS

Speaker: Fernando Maestre

University of Alicante

Host: James Sharpe

Place: Virtual

Planetary Biology Lectures

Virtual


29 April 2022, 11:00

To be announced

29 April 20222022EMBL - Sapienza LectureEMBL Rome

Speaker: Claire Wyart

Institut du Cerveau et de la Moelle Epiniere CHU, Paris

Host: Cornelius Gross/Andrea Mele

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL - Sapienza Lecture

EMBL Rome



6 May 2022, 13:00

Structural proteomics in bacterial cells

6 May 20222022Hamburg SpeakerEMBL Hamburg

Speaker: Francis O'Reilly

Berlin Institute of Technology

Host: Nikolay Dobrev, ( Wilmanns group)

Place: via Zoom VC

Hamburg Speaker

EMBL Hamburg


13 May 2022, 11:00

Randomness, geometry and stemness

13 May 20222022External Faculty SpeakerEMBL Heidelberg

Several molecular markers have been described to predict adult stem cell potential with great success, e.g., in tissues like the blood, where a clear hierarchy of functional cell types can be identified. In other tissues, neutral competitive dynamics has been reported to remove a large fraction of biochemically identifiable stem cells, thereby creating a severe mismatch between cell-specific biochemical identity and the actual role of them as functional stem cells within the collective forming the tissue. Several molecular markers have been described to predict adult stem cell potential with great success, e.g., in tissues like the blood, where a clear hierarchy of functional cell types can be identified. In other tissues, neutral competitive dynamics has been reported to remove a large fraction of biochemically identifiable stem cells, thereby creating a severe mismatch between cell-specific biochemical identity and the actual role of them as functional stem cells within the collective forming the tissue. In the case of the intestinal epithelium, this mismatch goes even further: In spite the number of biochemically identifiable (LGR5+) stem cells is the same in the crypts of both large and small intestines, lineage tracing techniques show that the number of them that actually play the role of stem cell displays remarkable differences. In that context, a natural question arises: How to...

Speaker: Bernat Corominas-Murtra

University of Graz

Host: Nicoletta Petridou

Place: Large Operon

External Faculty Speaker

EMBL Heidelberg


13 May 2022, 14:30

Deep Behavior Profiling and Associative Learning

13 May 20222022Seminar given by an external postdoc EMBL Rome

Behavior assessment is a cornerstone of neuroscience. Current molecular approaches have achieved high temporal precision of physiological measurements. Recent advances in machine vision, enable a similar level of precision in monitoring animal behavior. It is now possible to extract high-dimensional representation of animal sequences of movements and postures and break animal behavior down into subcategories and even into small behavioral motifs. Behavior assessment is a cornerstone of neuroscience. Current molecular approaches have achieved high temporal precision of physiological measurements. Recent advances in machine vision, enable a similar level of precision in monitoring animal behavior. It is now possible to extract high-dimensional representation of animal sequences of movements and postures and break animal behavior down into subcategories and even into small behavioral motifs. We have established an automated pipeline for deep behavior phenotyping and show its ability to capture specific deviations in adaptation and movement as well as differences in the detailed structure of behavioral dynamics. I will demonstrate these capacities in wild-type mice undergoing free exploration, as well as several models of Autism Spectrum Disorder. To examine contextual learning, we established a platform for the context-dependence of...

Speaker: Mikhail Kislin

Princeton Neuroscience Institute, Princeton, NJ

Host: Hiroki Asari

Place: Virtual seminar

Seminar given by an external postdoc

EMBL Rome


19 May 2022, 15:00

Molecular Genetic Studies of CNS Vascular Development and Disease

19 May 20222022EMBL Distinguished Visitor LectureEMBL Rome

Speaker: Jeremy Nathans

Department of Molecular Biology and Genetics Johns Hopkins University School of Medicine Baltimore, MD

Host: Cornelius Gross

Place: Virtual seminar

EMBL Distinguished Visitor Lecture

EMBL Rome


19 May 2022, 16:00

Culturing and managing complex soil microbiomes

19 May 20222022Symbnet seriesEMBL Heidelberg

Speaker: Jan van der Meer

Environmental and Evolutionary Microbiology Lab, University of Lausanne (UNIL), Switzerland

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


19 May 2022, 16:30

The Microbiome of Octocorals: Community structure, Function, and possible Metabolic Interactions

19 May 20222022Symbnet seriesEMBL Heidelberg

Speaker: Tina Keller Costa

Institute for Bioengineering and Biosciences, Instituto Superior Técnico (IST), Portugal

Place: via Zoom VC

Symbnet series

EMBL Heidelberg




24 May 2022, 14:00

Latest information from the world of Quantitative Phase Imaging

24 May 20222022Company RepresentativeEMBL Heidelberg

This presentation is important for everyone who would like to understand what QPI can do for her/his research. We would love to hear what problems you are facing when analyzing cells and how could we address them. Are you struggling with phototoxicity? Have you ever wondered if there is a quantitative label-free imaging method? Are your cells too sensitive to disturbances or staining? Have you ever wondered how many picograms your cells weigh? Are you not satisfied with the segmentation results and cell tracker performance? This presentation is important for everyone who would like to understand what QPI can do for her/his research. We would love to hear what problems you are facing when analyzing cells and how could we address them. Are you struggling with phototoxicity? Have you ever wondered if there is a quantitative label-free imaging method? Are your cells too sensitive to disturbances or staining? Have you ever wondered how many picograms your cells weigh? Are you not satisfied with the segmentation results and cell tracker performance?

Speaker: Tomáš Slabý, Zuzana Nováková

Telight

Host: Stefan Terjung, ALMF

Place: Virtual seminar

Company Representative

EMBL Heidelberg


27 May 2022, 11:00

Do animals use the same mechanisms to generate and regenerate complex organs?

27 May 20222022External Faculty SpeakerEMBL Heidelberg

Speaker: Michalis Averof

IGFL

Host: Hanh Vu

Place: Large Operon

External Faculty Speaker

EMBL Heidelberg


6 June 2022, 13:00

Probing the interface of drugs and the human gut microbiome

6 June 20222022Symbnet seriesEMBL Heidelberg

Speaker: Nassos Typas

Systems Microbiology Lab, EMBL, Germany

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


7 June 2022, 15:00

Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments

7 June 20222022Company RepresentativeEMBL Heidelberg

Discover Biology at Any Scale! Join us at this Seminar Series to learn the latest innovations in Spatial Biology from discovery to clinical research, multicellular to single cell & subcellular profiling and imaging, and how to analyze spatial data. For in-person attendees: Pre-bookable Project Consultations with the NanoString team follows the seminar. Meet the experts to discuss how to apply spatial profiling to your research projects. Discover Biology at Any Scale! Join us at this Seminar Series to learn the latest innovations in Spatial Biology from discovery to clinical research, multicellular to single cell & subcellular profiling and imaging, and how to analyze spatial data. For in-person attendees: Pre-bookable Project Consultations with the NanoString team follows the seminar. Meet the experts to discuss how to apply spatial profiling to your research projects. AGENDA: 14:45 - 15:00 - Registration for in-person attendees 15:00 - 15:05 - Introduction by Hosts 15:05 - 16:00 - Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments Dorothee Preimel, Technical Sales Specialist, NanoString Technologies 16:00 - 16:30 - CosMx™ Spatial Molecular Imager -True Single-Cell In Situ Solution Mathias Holpert, Sr. Product Application Scientist, NanoString Technologies 16:30 - 16:45 - Closing remarks &...

Speaker: Dorothee Preimel

Technical Sales Specialist, NanoString Technologies

Host: Vladimir Benes

Place: Small Operon

Company Representative

EMBL Heidelberg


7 June 2022, 16:00

CosMx™ Spatial Molecular Imager -True Single-Cell In Situ Solution

7 June 20222022Company RepresentativeEMBL Heidelberg

Discover Biology at Any Scale! Join us at this Seminar Series to learn the latest innovations in Spatial Biology from discovery to clinical research, multicellular to single cell & subcellular profiling and imaging, and how to analyze spatial data. For in-person attendees: Pre-bookable Project Consultations with the NanoString team follows the seminar. Meet the experts to discuss how to apply spatial profiling to your research projects. Discover Biology at Any Scale! Join us at this Seminar Series to learn the latest innovations in Spatial Biology from discovery to clinical research, multicellular to single cell & subcellular profiling and imaging, and how to analyze spatial data. For in-person attendees: Pre-bookable Project Consultations with the NanoString team follows the seminar. Meet the experts to discuss how to apply spatial profiling to your research projects. AGENDA: 14:45 - 15:00 - Registration for in-person attendees 15:00 - 15:05 - Introduction by Hosts 15:05 - 16:00 - Morphology Driven High-Plex Spatial Analysis of Tissue Microenvironments Dorothee Preimel, Technical Sales Specialist, NanoString Technologies 16:00 - 16:30 - CosMx™ Spatial Molecular Imager -True Single-Cell In Situ Solution Mathias Holpert, Sr. Product Application Scientist, NanoString Technologies 16:30 - 16:45 - Closing remarks &...

Speaker: Mathias Holpert

Senior Product Application Scientist, NanoString Technologies

Host: Vladimir Benes

Place: Small Operon

Company Representative

EMBL Heidelberg


10 June 2022, 11:00

MBD5 and MBD6 couple DNA methylation to gene silencing through the J-domain protein SILENZIO

10 June 20222022Seminar given by an external postdoc EMBL Rome

Speaker: Lucia Ichino

UCLA, Dept of Biological Chemistry, Los Angeles, USA

Host: Matthieu Boulard

Place: Conf Room/Building 14

Seminar given by an external postdoc

EMBL Rome



10 June 2022, 13:00

Intrinsically disordered RNA-binding proteins in cellular phase transitions

10 June 20222022External Faculty SpeakerEMBL Heidelberg

Join Zoom Meeting https://embl-org.zoom.us/j/96838401413?pwd=bGJSUlpKNUhSb0toZFFCRlhhWVdV… Meeting ID: 968 3840 1413 Passcode: BlueSCB Join Zoom Meeting https://embl-org.zoom.us/j/96838401413?pwd=bGJSUlpKNUhSb0toZFFCRlhhWVdV… Meeting ID: 968 3840 1413 Passcode: BlueSCB *********** Despite an extensive membrane network, eukaryotic cells contain numerous types of membrane-less organelles and condensates formed by liquid-liquid phase separation. Numerous studies have shown that condensate formation is often driven and regulated by RNA-binding proteins. From work on human RNA-binding proteins, SRP19, to new research on SMAUG1, several themes of protein disorder, short-linear motifs and regulation will be presented. With SMAUG1, we have found that multivalent phospho-dependent interactions play a strong negative regulatory role in biological condensation. Our data also indicate that this regulatory step is heavily intertwined with additional regulation mechanisms that need to be uncovered, highlighting the importance of...

Speaker: Kellie Dean

University College Cork

Host: Balint Meszaros

Place: Small Operon

External Faculty Speaker

EMBL Heidelberg



13 June 2022, 14:00

Understanding the global biogeography and ecology of soil microbial communities in a warmer and more arid planet

13 June 20222022Planetary Biology LecturesVirtual

Join Zoom Meeting https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNr… Meeting ID: 936 0817 9765 Passcode: PBLS Join Zoom Meeting https://embl-org.zoom.us/j/93608179765?pwd=dU1aTERLdm5YVEl5MlJ4VVJNMGNr… Meeting ID: 936 0817 9765 Passcode: PBLS

Speaker: Fernando Maestre

University of Alicante

Host: James Sharpe

Place: Virtual

Planetary Biology Lectures

Virtual


14 June 2022, 15:00

Coupling single-cell genomics and transcriptomics with ResolveOME™ amplification chemistry to illuminate oncogenic and drug resistance mechanisms

14 June 20222022Company RepresentativeEMBL Heidelberg

To elucidate drug resistance mechanisms in cancer and to deconvolve the molecular basis of variability in treatment responses, it is paramount to apply approaches that integrate multi-omics data. Existing methodologies aiming to couple genomic and transcriptomic information are limited in that the genomic information is based on a targeted approach, or non-targeted methods do not provide complete and uniform coverage, providing insight into only a small fraction of the genome. To elucidate drug resistance mechanisms in cancer and to deconvolve the molecular basis of variability in treatment responses, it is paramount to apply approaches that integrate multi-omics data. Existing methodologies aiming to couple genomic and transcriptomic information are limited in that the genomic information is based on a targeted approach, or non-targeted methods do not provide complete and uniform coverage, providing insight into only a small fraction of the genome. BioSkryb Genomics developed a novel method, ResolveOME, to ascertain genomic variation and transcriptomic state of the same individual cell. The workflow unifies template-switching full-transcript RNA-Seq chemistry and whole genome amplification (WGA), followed by affinity purification of first-strand cDNA and subsequent separation of the RNA/DNA fractions for sequencing library preparation. In the ResolveOME...

Speaker: Mark Lynch

BioSkryb Genomics, Durham, North Carolina

Host: Vladimir Benes

Place: Small Operon

Company Representative

EMBL Heidelberg


15 June 2022, 11:00

Investigating how the EphB6 pseudokinase mediates cell-cell communication using CLEM and Cryo-ET

15 June 20222022Seminar given by an external postdoc EMBL Heidelberg

Speaker: Liang Lung-Yu

Walter and Eliza Hall Institute of Medical Research, Parkville

Host: Svetlana Dodonova

Place: Room 202

Seminar given by an external postdoc

EMBL Heidelberg


16 June 2022, 15:00

Coupling single-cell genomics and transcriptomics with ResolveOME™ amplification chemistry to illuminate oncogenic and drug resistance mechanisms

16 June 20222022Company RepresentativeEMBL Heidelberg

To elucidate drug resistance mechanisms in cancer and to deconvolve the molecular basis of variability in treatment responses, it is paramount to apply approaches that integrate multi-omics data. Existing methodologies aiming to couple genomic and transcriptomic information are limited in that the genomic information is based on a targeted approach, or non-targeted methods do not provide complete and uniform coverage, providing insight into only a small fraction of the genome. To elucidate drug resistance mechanisms in cancer and to deconvolve the molecular basis of variability in treatment responses, it is paramount to apply approaches that integrate multi-omics data. Existing methodologies aiming to couple genomic and transcriptomic information are limited in that the genomic information is based on a targeted approach, or non-targeted methods do not provide complete and uniform coverage, providing insight into only a small fraction of the genome. BioSkryb Genomics developed a novel method, ResolveOME, to ascertain genomic variation and transcriptomic state of the same individual cell. The workflow unifies template-switching full-transcript RNA-Seq chemistry and whole genome amplification (WGA), followed by affinity purification of first-strand cDNA and subsequent separation of the RNA/DNA fractions for sequencing library preparation. In the ResolveOME...

Speaker: Mark Lynch

Vice President EMEA - BioSkryb Genomics

Host: Vladimir Benes

Place: Small Operon

Company Representative

EMBL Heidelberg


21 June 2022, 10:00

KingFisher Sample Purification Systems – automatized magnetic bead isolation for DNA, RNA, Cells and Proteins

21 June 20222022Company RepresentativeEMBL Heidelberg

Already using magnetic beads in your experimental workflow or looking for ways to save hands on time and get more consistent results? Then join our Webinar and learn about the KingFisher Sample Purification Systems and their versatile applications ranging from DNA, RNA and Protein isolation to the isolation and activation of entire cells. Already using magnetic beads in your experimental workflow or looking for ways to save hands on time and get more consistent results? Then join our Webinar and learn about the KingFisher Sample Purification Systems and their versatile applications ranging from DNA, RNA and Protein isolation to the isolation and activation of entire cells.

Speaker: Msc. Michael Kostka

Thermo Fisher Scientific

Host: Mandy Rettel - PCF

Place: Large Operon

Company Representative

EMBL Heidelberg


23 June 2022, 16:00

Deciphering cellular phenotypes using biophysical proteomics

23 June 20222022Symbnet seriesEMBL Heidelberg

Speaker: Mikhail Savitski

Stability Proteomics for assessing the state of the Proteome; Proteomics Core Facility | EMBL, Germany

Place: via Zoom VC

Symbnet series

EMBL Heidelberg


23 June 2022, 16:30

How the larva got its fly: the co-option of immune mechanisms in the evolution of metamorphosis

23 June 20222022Symbnet seriesEMBL Heidelberg

Speaker: Élio Sucena

Evolution and Development Lab | FCG-IGC, Portugal

Place: via Zoom VC

Symbnet series

EMBL Heidelberg