EMBL Seminars

At EMBL, experts from institutes throughout the world speak on a wide range of scientific and technical topics

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4 March 2026, 15:00

EMBL Skills & Careers webinar: Negotiating your first group leader position

4 March 20262026Career EventEMBL Heidelberg

Description Abstract Group leaders based in Germany Austria and the US will share their experience of negotiating their group leader role Following the speakers introductory presentations participants will have the opportunity to ask questions during a panel discussion Join to gain insights into the negotiation process and how to prepare to make the most of your first group leader position Please register for this zoom webinar https embl org zoom us webinar register WN NNV9KmXCRFSGCfRgqJSxEQ registration Please note that the talk will be recorded For the FAQ section as a zoom participant please use either the chat function the host will read out your question... Abstract Group leaders based in Germany, Austria, and the US, will share their experience of negotiating their group leader role. Following the speakers' introductory presentations, participants will have the opportunity to ask questions during a panel discussion. Join to gain insights into the negotiation process and how to prepare to make the most of your first group leader position! Please register for this zoom webinar: https://embl-org.zoom.us/webinar/register/WN_NNV9KmXCRFSGCfRgqJSxEQ#/registration Please note that the talk will be recorded. *For the FAQ section, as a zoom participant, please use either the chat function (the host will read out your question).

Speaker(s): Leslie Caromile, Assistant Professor at University of Connecticut Health Center, USA | Irma Querques, Assistant Professor at Max Perutz Labs, Austria | Margot Smit, Junior Group Leader at University of Tübingen, Germany
Host: EMBL Fellows' Skills and Career Development

Place: Virtual seminar

EMBL Heidelberg

Additional information

Abstract
Group leaders based in Germany, Austria, and the US, will share their experience of negotiating their group leader role. Following the speakers' introductory presentations, participants will have the opportunity to ask questions during a panel discussion. Join to gain insights into the negotiation process and how to prepare to make the most of your first group leader position!

Please register for this zoom webinar: https://embl-org.zoom.us/webinar/register/WN_NNV9KmXCRFSGCfRgqJSxEQ#/registration

Please note that the talk will be recorded.
*For the FAQ section, as a zoom participant, please use either the chat function (the host will read out your question).


20 March 2026, 13:00

An EPR view on contacts, crowding and conformations of intrinsically disordered biopolymers

20 March 20262026Hamburg SpeakerEMBL Hamburg

Description AbstractBridging the concentration gap between the dispersed state of intrinsically disordered biopolymers and their high concentration states relevant for cellular environment including membrane less organelles as well as for food biochemistry and food technology is a serious challenge In this talk I will present an approach based on the conventional and newly developed pulse EPR techniques and aimed to describe the spatial and conformational distributions in biomolecular condensates and weak aggregates This methodology can potentially also shed light on the biomolecules solvation Furthermore comparison of pulse EPR data with small angle scattering and THz calorimetry data might appear very interesting Importantly new EPR method to determine local biopolymer density will be presented which might appear an efficient support for SAXS SANS based determination of conformational ensembles of intrinsically disordered biomolecules About the speaker Biographical information about the speaker Meet the speakerTo meet with the speaker informally after the talks sign up here add link We especially encourage predocs and postdocs to take advantage of this opportunity Attachments Link to a file for example a pdf of the seminar s programme the file can be uploaded on the intranet Connection detailsZoom link Meeting ID XXXXXXXXX Password XXXXXXX Please note that the talk will yes not be recorded For the FAQ section as a zoom participant please use either the chat function the host will read out your question or the raise your hand function and turn on your microphone... AbstractBridging the concentration gap between the dispersed state of intrinsically disordered biopolymers and their high-concentration states relevant for cellular environment, including membrane-less organelles, as well as for food biochemistry and food technology, is a serious challenge. In this talk, I will present an approach based on the conventional and newly developed pulse EPR techniques and aimed to describe the spatial and conformational distributions in biomolecular condensates and weak aggregates. This methodology can potentially also shed light on the biomolecules’ solvation. Furthermore, comparison of pulse EPR data with small angle scattering and THz calorimetry data might appear very interesting. Importantly, new EPR method to determine local biopolymer density will be presented, which might appear an efficient support for SAXS/SANS based determination of conformational...

Speaker(s): Maxim Yulikov, ETH Zuerich, Switzerland
Host: Clement Blanchet, EMBL Hamburg Unit

Place: Seminar Room 48e

EMBL Hamburg

Additional information

Abstract
Bridging the concentration gap between the dispersed state of intrinsically disordered biopolymers and their high-concentration states relevant for cellular environment, including membrane-less organelles, as well as for food biochemistry and food technology, is a serious challenge. In this talk, I will present an approach based on the conventional and newly developed pulse EPR techniques and aimed to describe the spatial and conformational distributions in biomolecular condensates and weak aggregates. This methodology can potentially also shed light on the biomolecules’ solvation. Furthermore, comparison of pulse EPR data with small angle scattering and THz calorimetry data might appear very interesting. Importantly, new EPR method to determine local biopolymer density will be presented, which might appear an efficient support for SAXS/SANS based determination of conformational ensembles of intrinsically disordered biomolecules.

 

About the speaker
[Biographical information about the speaker].

Meet the speaker
To meet with the speaker informally after the talks,sign up here [add link]. We especially encourage predocs and postdocs to take advantage of this opportunity.

Attachments
[Link to a file (for example a pdf of the seminar’s programme) - the file can be uploaded on the intranet]

Connection details
Zoom*: [link] (Meeting ID: [XXXXXXXXX], Password: [XXXXXXX])

Please note that the talk will yes/not be recorded.
*For the FAQ section, as a zoom participant, please use either the chat function (the host will read out your question) or the “raise your hand” function and turn on your microphone.


27 March 2026, 15:00

EMBL Skills & Careers webinar: Careers in core facilities and scientific services

27 March 20262026Career EventVirtual

Description AbstractProfessionals working in core facilities and scientific services will share their career paths and experiences transitioning from academia into service oriented scientific roles Join this webinar to gain insights into daily work in core facilities the skills required to succeed key differences compared to PhD or postdoctoral research and practical advice for those considering a similar career move Please register for this zoom webinar https embl org zoom us webinar register WN f2QNItDPSoq0EUxi5qPfdwPlease note that the talk will be recorded For the FAQ section as a zoom participant please use either the chat function the host will read out your question... AbstractProfessionals working in core facilities and scientific services will share their career paths and experiences transitioning from academia into service-oriented scientific roles. Join this webinar to gain insights into daily work in core facilities, the skills required to succeed, key differences compared to PhD or postdoctoral research, and practical advice for those considering a similar career move.Please register for this zoom webinar: https://embl-org.zoom.us/webinar/register/WN_f2QNItDPSoq0EUxi5qPfdwPlease note that the talk will be recorded.*For the FAQ section, as a zoom participant, please use either the chat function (the host will read out your question).

Speaker(s): Marvin Albert, Staff of D-BSSE Single Cell Facility at ETH Zürich, Switzerland | João Sequeira, Head of the Scientific Computing Core Facility at HCEEM, Hungary | Andy Riddell, Head of Flow Cytometry Science and Technology Platform at The Francis Crick Institute, UK
Host: EMBL Fellows' Skills and Career Development

Place: Virtual

Virtual

Additional information

Abstract
Professionals working in core facilities and scientific services will share their career paths and experiences transitioning from academia into service-oriented scientific roles. Join this webinar to gain insights into daily work in core facilities, the skills required to succeed, key differences compared to PhD or postdoctoral research, and practical advice for those considering a similar career move.

Please register for this zoom webinar: https://embl-org.zoom.us/webinar/register/WN_f2QNItDPSoq0EUxi5qPfdw

Please note that the talk will be recorded.
*For the FAQ section, as a zoom participant, please use either the chat function (the host will read out your question).


10 April 2026, 11:00

Super-resolution imaging of chromatin in health and disease

10 April 20262026External Faculty SpeakerEMBL Rome

Description AbstractSuper resolution microscopy has opened new possibilities for visualizing chromatin architecture in situ at nanoscale resolution Leveraging quantitative super resolution imaging we revealed the heterogeneous nature of nucleosome folding and demonstrated that chromatin structure at both nano and meso scales is highly plastic dynamically remodeling in response to chemical and mechanical cues in health and disease By combining biologically interpretable feature extraction with machine learning we further showed that cells can be accurately classified into distinct states based solely on their multi scale chromatin organization while also identifying the specific chromatin features that drive classification thus offering mechanistic insight into cell state regulation... AbstractSuper-resolution microscopy has opened new possibilities for visualizing chromatin architecture in situ at nanoscale resolution. Leveraging quantitative super-resolution imaging, we revealed the heterogeneous nature of nucleosome folding and demonstrated that chromatin structure at both nano- and meso-scales is highly plastic, dynamically remodeling in response to chemical and mechanical cues in health and disease. By combining biologically interpretable feature extraction with machine learning, we further showed that cells can be accurately classified into distinct states based solely on their multi-scale chromatin organization, while also identifying the specific chromatin features that drive classification, thus offering mechanistic insight into cell-state regulation.

Speaker(s): Melike Lakadamyali, Perelman School of Medicine, University of Pennsylvania, USA
Host: Alvaro Crevenna

Place: Conf Room/Building 14

EMBL Rome

Additional information

Abstract
Super-resolution microscopy has opened new possibilities for visualizing chromatin architecture in situ at nanoscale resolution. Leveraging quantitative super-resolution imaging, we revealed the heterogeneous nature of nucleosome folding and demonstrated that chromatin structure at both nano- and meso-scales is highly plastic, dynamically remodeling in response to chemical and mechanical cues in health and disease. By combining biologically interpretable feature extraction with machine learning, we further showed that cells can be accurately classified into distinct states based solely on their multi-scale chromatin organization, while also identifying the specific chromatin features that drive classification, thus offering mechanistic insight into cell-state regulation.


17 April 2026, 11:00

To be announced

17 April 20262026External Faculty SpeakerEMBL Rome

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Speaker(s): Daniele Canzio, University of California San Francisco, USA
Host: Mathieu Boulard

Place: Conf Room/Building 14

EMBL Rome


24 April 2026, 11:00

To be announced

24 April 20262026EMBL - Sapienza LectureEMBL Rome

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Speaker(s): Greg Hannon, University of Cambridge, United Kingdom
Host: Cornelius Gross

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL Rome


29 May 2026, 11:00

To be announced

29 May 20262026EMBL Distinguished Visitor LectureEMBL Rome

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Speaker(s): Fred Rusty Gage, The Salk Institute, USA
Host: Mathieu Boulard

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL Rome


11 September 2026, 11:00

Polycomb proteins and 3D genome architecture in chromatin memory from flies to mouse

11 September 20262026External Faculty SpeakerEMBL Rome

Description AbstractEpigenetic components regulate many biological phenomena during development and normal physiology When dysregulated epigenetic components can also accompany or drive diseases One main class of epigenetic components are Polycomb group proteins Originally Polycomb proteins were shown to silence gene expression We found that this function involves the regulation of 3D chromosome folding and we found that Polycomb components can induce the formation of long distance interactions or chromatin loops that may play instructive roles in gene regulation as well as serve as scaffolding elements that contribute to enhancer promoter specificity Perturbation of Polycomb components is involved in human cancer and leads to tumorigenesis in flies Surprisingly even upon a transient depletion followed by restoration of the full Polycomb compendium epithelial cells lose their normal differentiated fate continue proliferating and establish aggressive tumors demonstrating that cancer can have a fully epigenetic origin Similarly transient perturbation of histone acetylation in mouse ES cells and gastruloids shows that they can record chromatin changes and that this results in cellular memory of the perturbation states The implication of these data will be discussed... AbstractEpigenetic components regulate many biological phenomena during development and normal physiology. When dysregulated, epigenetic components can also accompany or drive diseases. One main class of epigenetic components are Polycomb group proteins. Originally, Polycomb proteins were shown to silence gene expression. We found that this function involves the regulation of 3D chromosome folding and we found that Polycomb components can induce the formation of long-distance interactions or chromatin loops that may play instructive roles in gene regulation as well as serve as scaffolding elements that contribute to enhancer-promoter specificity. Perturbation of Polycomb components is involved in human cancer and leads to tumorigenesis in flies. Surprisingly, even upon a transient depletion followed by restoration of the full Polycomb compendium, epithelial cells lose their normal...

Speaker(s): Giacomo Cavalli, CNRS and University of Montpellier, France
Host: Jamie Hackett

Place: Conf Room/Building 14

EMBL Rome

Additional information

Abstract


Epigenetic components regulate many biological phenomena during development and normal physiology. When dysregulated, epigenetic components can also accompany or drive diseases. One main class of epigenetic components are Polycomb group proteins. Originally, Polycomb proteins were shown to silence gene expression. We found that this function involves the regulation of 3D chromosome folding and we found that Polycomb components can induce the formation of long-distance interactions or chromatin loops that may play instructive roles in gene regulation as well as serve as scaffolding elements that contribute to enhancer-promoter specificity. Perturbation of Polycomb components is involved in human cancer and leads to tumorigenesis in flies. Surprisingly, even upon a transient depletion followed by restoration of the full Polycomb compendium, epithelial cells lose their normal differentiated fate, continue proliferating and establish aggressive tumors, demonstrating that cancer can have a fully epigenetic origin. Similarly, transient perturbation of histone acetylation in mouse ES cells and gastruloids shows that they can record chromatin changes and that this results in cellular memory of the perturbation states. The implication of these data will be discussed.


16 October 2026, 11:00

To be announced

16 October 20262026External Faculty SpeakerEMBL Rome

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Speaker(s): Alex Schier, University of Basel, Switzerland
Host: Gemma Noviello

Place: Conf Room/Building 14

EMBL Rome


20 November 2026, 11:00

To be announced

20 November 20262026EMBL - Sapienza LectureEMBL Rome

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Speaker(s): Bob Datta, Harvard University, USA
Host: Arianna Rinaldi

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL Rome