ERC Investigators

Cellular innovation driving nervous system evolution

A neuron type atlas of the annelid brain: development and evolution of chemosensory-motor circuits

Exploring the human gut microbiome at strain resolution

Characterisation of the cancer-associated microbiome

Two facets of viral RNA: mechanistic studies of transcription and replication by influenza-like viral polymerases and detection by the innate immune system

Cell division and the origin of embryonic aneuploidy in preimplantation mouse development

Deciphering Cis-Regulatory Principles of Transcriptional regulation: Combining large-scale genetics and genomics to dissect functional principles of genome regulation during embryonic development

Cis-regulatory variation: Using natural genetic variation to dissect cis-regulatory control of embryonic development

Functional wiring of the core neural network of innate fear

Exploring mechanisms of gene repression and escape during X-chromosome inactivation

Exploring the interface between cell metabolism and gene regulation: from mRNA interactomes to ‘REM Networks’

Self-organisation across the scales in early mammalian development

Dynamic architecture of the RNA polymerase I transcription initiation machinery

Dissecting quantitative traits and their underlying genetic interactions via systematic genome editing

High-throughput dissection of the genetics underlying complex traits

Metabolism of a cell pictured by single-cell approach

The birth of protein complexes

Structure and mechanism of viral and cellular membrane fusion machineries

Structural basis for the coordination of chromosome architecture by condensin complexes

Relationship of Somatic Structural Variation Mosaicism to Aging and Disease Phenotypes

Next generation single molecule protein fluorescence

Development of advanced optical tools for studying cellular mechanics at high spatial and temporal resolution

Structural cell biology in situ using superresolution microscopy

Re(defining) CD4+ T cell identities one cell at a time

uCARE 2019 – 2024

Understanding & circumventing antibiotic resistance

Oscillatory signaling dynamics – a quantitative approach to reveal their origin and function in development

Atlas of cell-type specific nuclear pore complex structures

Dissecting the functional importance of eukaryotic protein phosphorylation

Understanding Cerebral Malaria using 3D Blood-Brain Barrier models

The establishment and function of dorsiventral boundaries in plant organs

Development of chemical biology tools for the elucidation of protein phosphatase-1 substrates and druggability

Dissecting the molecular mechanism of catastrophic DNA rearrangement in cancer

In situ structural analysis of molecular crowding and phase separation

Non-coding RNA pathways and the mammalian male germline

Towards a dynamic quantitative understanding of neuronal microglial interactions

Small RNA-guided complex machinery for epigenetic silencing

NMD complexes: eukaryotic mRNA quality control

Defining the impact of chromosome instability in tumour initiation, maintenance and relapse

Genetics of Individuality

Decoding Context-Dependent Genetic Networks in vivo

Decoding Context-Dependent Genetic Networks in vivo