{"id":78545,"date":"2026-04-14T10:15:17","date_gmt":"2026-04-14T08:15:17","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=78545"},"modified":"2026-04-14T10:15:21","modified_gmt":"2026-04-14T08:15:21","slug":"we-are-embl-bertha-rueda-zarazua-on-reducing-health-inequalities","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/people-perspectives\/we-are-embl-bertha-rueda-zarazua-on-reducing-health-inequalities\/","title":{"rendered":"We are EMBL: Bertha Rueda-Zarazua on reducing health inequalities"},"content":{"rendered":"\n<p>Bertha Rueda-Zarazua, Postdoctoral Fellow in the <a href=\"https:\/\/www.ebi.ac.uk\/research\/cortes-ciriano\/\">Cortes Ciriano Group at EMBL-EBI<\/a>, is working to make science fairer through the SAMBAI project, supported by the Cancer Grand Challenges partnership funded by Cancer Research UK (award reference: CGCATF-2023 \/ 100026). Her research focuses on identifying factors that influence cancer outcomes in African-ancestry communities.\u00a0<\/p>\n\n\n\n<p>Beyond science, her world moves to the rhythm of salsa, painting, and short films.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Tell me about your background.<\/h3>\n\n\n\n<p>I hold a Bachelor\u2019s degree in pharmaceutical biology. I specialised in pharmaceutical care because it allowed me to work closely with patients. I then pursued a Master\u2019s degree in neurobiology, which introduced me to human genomics, especially mitochondrial genomics. During my PhD at the <a href=\"https:\/\/www.unam.mx\/\">National Autonomous University of Mexico<\/a>, I focused on cancer genomics and became especially interested in cancer inequities.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What brought you to EMBL-EBI?<\/h3>\n\n\n\n<p>Back in Mexico, I always wanted to study genetics, but my access to this field was limited. During my Master\u2019s degree, I realised I wanted to do bioinformatics, and I completely fell in love with computational genomics.&nbsp;<\/p>\n\n\n\n<p>When I finally had the chance to choose postgraduate studies, I decided to reconnect with genomics, and EMBL-EBI is the best place to grow in this field.&nbsp;&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Tell me about your work at EMBL-EBI.<\/h3>\n\n\n\n<p>I\u2019m part of the <a href=\"https:\/\/www.ebi.ac.uk\/about\/news\/announcements\/project-sambai-addressing-cancer-disparities\/\">SAMBAI Project<\/a>, which stands for Social, Ancestry, Molecular and Biological Analysis of Inequalities. This work is supported by the <a href=\"https:\/\/www.cancergrandchallenges.org\/\">Cancer Grand Challenges<\/a> partnership funded by Cancer Research UK. Our goal is to identify the factors that can cause or influence different cancer outcomes in underserved populations, particularly those of recent African ancestry.&nbsp;&nbsp;<\/p>\n\n\n\n<p>SAMBAI is a unique opportunity to contribute to more equitable science. My role in the project is to analyse large-scale patient data to understand the biological and social factors shaping cancer outcomes \u2013 a discovery process I find very exciting.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Why is it important to consider population-specific differences in cancer outcomes?<\/h3>\n\n\n\n<p>I like to use a simple example: just as children and adults cannot receive identical treatments, we cannot assume that medical findings apply equally to all populations.<\/p>\n\n\n\n<p>Previously, I studied adenocarcinoma in Mexican patients and compared our findings with European data. Historically, medicine has been built on European ancestry populations, and there hasn&#8217;t been enough research on what this means for other demographics.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What differences did you observe in Mexican patients?<\/h3>\n\n\n\n<p>We wanted to understand whether conclusions from European data could be generalised. We discovered that Mexican patients lacked a well-known tobacco-related mutational signature, which is commonly seen in European groups. None of our patients showed this signature, even those with long smoking histories.&nbsp;<\/p>\n\n\n\n<p>This is just one example showing how essential it is to study population-specific genomic features to design better therapies, identify relevant molecular targets, and produce evidence-based public health policies.&nbsp;&nbsp;<\/p>\n\n\n\n<p>We must explore underserved populations to create fairer medicine. I hope to contribute to reducing inequalities in access to health, knowledge, and science. I truly believe this will shape the future of medicine.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What personal experiences led you to develop this passion for biology and research?&nbsp;<\/h3>\n\n\n\n<p>During my PhD, teaching reignited my passion for biology, pushing me to fully understand the topics I was discussing. One question led to another, and soon I recognised in my students the same curiosity I remember from when I discovered science as a child.&nbsp;<\/p>\n\n\n\n<p>It expanded my knowledge and triggered my love for research. It enabled me to question and contribute, in my own way, to modern science.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Did you always know you wanted to become a scientist?&nbsp;<\/h3>\n\n\n\n<p>Not at all. As a child, I wanted to be a fashion designer. Later, as a teenager, I dreamed of studying communication. In the end, a New Year\u2019s Eve coin toss pushed me toward science.&nbsp;<\/p>\n\n\n\n<p>Still, I hope to explore communication someday. Many people believe science isn\u2019t for them, but science is part of everyday life. Sharing this idea is very important to me.&nbsp;<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Besides science, what are your passions?&nbsp;<\/h3>\n\n\n\n<p>Dancing, especially salsa. For me, it\u2019s pure joy and has always helped me connect with people. I like to call that my superpower.&nbsp;<br \/>I also love art in all forms. I enjoy painting and designing posters, presentations, and anything colourful. And I\u2019m a big fan of cinema. As a teenager, I used to make short films with my friends. <strong>&nbsp;&nbsp;<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bertha Rueda-Zarazua, a postdoctoral fellow working in cancer genomics, shares her insights on making science more accessible and supporting historically underserved groups.<\/p>\n","protected":false},"author":187,"featured_media":78679,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17593,11054],"tags":[28,17275,4732,36,75,14003],"embl_taxonomy":[11080,2906],"class_list":["post-78545","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-people-perspectives","category-perspectives","tag-bioinformatics","tag-cortes-ciriano","tag-embl-international-phd-programme","tag-embl-ebi","tag-phd","tag-we-are-embl","embl_taxonomy-cortes-ciriano-group","embl_taxonomy-embl-ebi"],"acf":{"vfwp-news_embl_taxonomy":[2906,11080],"featured":true,"show_featured_image":false,"field_target_display":"both","field_article_language":{"value":"english","label":"English"},"article_intro":"<p>Bertha Rueda-Zarazua, a postdoctoral fellow working in cancer genomics, shares her insights on making science more accessible and supporting historically underserved groups<\/p>\n","related_links":false,"source_article":false,"in_this_article":false,"press_contact":"None","article_translations":false,"languages":""},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"442a4893-2c31-4523-b9eb-fb1ee4bd2037\";i:2;s:36:\"c365de00-bbe7-41f8-978d-1b967a5221b1\";}","parents":[],"name":["Cortes Ciriano Group"],"slug":"cortes-ciriano-group","description":"What &gt; 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