{"id":72271,"date":"2024-12-16T11:01:54","date_gmt":"2024-12-16T10:01:54","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=72271"},"modified":"2025-02-17T09:55:35","modified_gmt":"2025-02-17T08:55:35","slug":"cute-molecules-and-the-scientists-who-adore-them-veijo-salo","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/people-perspectives\/cute-molecules-and-the-scientists-who-adore-them-veijo-salo\/","title":{"rendered":"Cute molecules and the scientists who adore them: Veijo Salo"},"content":{"rendered":"\n
\n
\n

\n \n The cute side of science \n <\/path>\n <\/svg>\n <\/a>\n <\/h3>\n

Behind every discovery lies a story. Often this story is of a scientist and their passion and awe for nature\u2019s design.\r\n\r\n
 \r\n
\r\n\r\n\r\nWe’ve asked some of our scientists, from across EMBL sites, to talk about the molecules that capture their imaginations and make them smile. These stories reveal the surprising beauty, humour, and charm in the molecular structures that power life itself. We invite you to explore them and fall in love with the molecules, like these scientists have.<\/p>\n <\/div>\n<\/article>\n\n\n\n\n

\u201cMy favourite protein, called seipin<\/a>, is the cell\u2019s molecular bubble blower: it controls the production of fat bubbles, called lipid droplets, inside the cell. Scientists used to think that these bubbles were just randomly accumulated fat, but nowadays, we know that the cell uses them to store excess fat until they are needed either to generate energy, enable cell growth, or produce hormones in specialised cells. This storage is highly controlled, and my beloved protein, seipin, is the key player. However, we still don\u2019t know how it works, which makes it very mysterious and fascinating.<\/p>\n\n\n\n

\u201cSeipin has a peculiar shape, similar to a spiky ring, which works like a soap bubble blower: it shapes fat into bubbles, controls their size and ensures they don\u2019t break off. It looks somewhat like when you are blowing a bubble but it doesn\u2019t get released from the loop. It\u2019s remarkable how sturdy the seipin\u2013fat bubble combo is. If you have ever tried to make bubbles bigger and bigger without releasing or popping them, you\u2019ll know how difficult seipin\u2019s task is!<\/p>\n\n\n\n

\u201cEach cell holds <\/strong>hundreds of seipin\u2013fat bubble combos, which communicate with each other and create a network, similar to a plumbing system. This results in a chain of bubbles being released at once, just a moment before they all fly away.\u201d<\/p>\n\n\n\n

<\/div>\n\n\n\n

Veijo Salo (Finland), Postdoctoral Fellow, Mahamid Group<\/a>, EMBL Heidelberg<\/p>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"

Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell\u2019s molecular \u2018bubble blower\u2019.<\/p>\n","protected":false},"author":165,"featured_media":72279,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17593],"tags":[64,18799,5786,43,542,17693,5752],"embl_taxonomy":[9796,19329,5152],"class_list":["post-72271","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-people-perspectives","tag-cell-biology","tag-cute-proteins","tag-finland","tag-heidelberg","tag-mahamid","tag-molecular-systems-biology","tag-protein-structure","embl_taxonomy-embl-heidelberg","embl_taxonomy-mahamid-group","embl_taxonomy-molecular-systems-biology"],"acf":{"vfwp-news_embl_taxonomy":[9796,19329,5152],"featured":true,"show_featured_image":false,"field_target_display":"embl","field_article_language":{"value":"english","label":"English"},"article_intro":"

Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell\u2019s molecular \u2018bubble blower\u2019<\/p>\n","related_links":[{"link_description":"Cute molecules and the scientists who adore them: Sofia Rucli ","link_url":"https:\/\/www.embl.org\/news\/people-perspectives\/cute-molecules-and-the-scientists-who-adore-them-sofia-rucli\/"},{"link_description":"Cute molecules and the scientists who adore them: Maria Costanzo ","link_url":"https:\/\/www.embl.org\/news\/people-perspectives\/cute-molecules-and-the-scientists-who-adore-them-maria-costanzo\/"}],"source_article":false,"in_this_article":false,"press_contact":"None","article_translations":false,"languages":""},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"b14d3f13-5670-44fb-8970-e54dfd9c921a\";i:1;s:36:\"89e00fee-87f4-482e-a801-4c3548bb6a58\";i:2;s:36:\"ab46b6d4-71d8-49f8-b2f4-b326d4c8ea4e\";}","parents":[],"name":["EMBL Heidelberg"],"slug":"embl-heidelberg","description":"Where > All EMBL sites > EMBL 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