{"id":61919,"date":"2023-09-05T12:00:07","date_gmt":"2023-09-05T10:00:07","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=61919"},"modified":"2024-04-26T11:16:24","modified_gmt":"2024-04-26T09:16:24","slug":"erc-starting-grants-for-two-embl-heidelberg-researchers","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/lab-matters\/erc-starting-grants-for-two-embl-heidelberg-researchers\/","title":{"rendered":"ERC starting grants for two EMBL Heidelberg researchers"},"content":{"rendered":"\n<p>Two EMBL Heidelberg group leaders have received prestigious <a href=\"https:\/\/erc.europa.eu\/apply-grant\/starting-grant\">European Research Council (ERC) Starting Grants.<\/a> Jordi van Gestel and Maria Zimmermann-Kogadeeva will each receive 1.5 million EUR for a period of five years to carry out cutting-edge fundamental research.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Studying microbial predation in soil&nbsp;<\/strong><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.embl.org\/groups\/van-gestel\/\">Jordi van Gestel and his group<\/a> investigate how collective microbial development evolves in the context of predation. To do so, they combine different experimental approaches, including microfluidics, functional genomics, and high-content expression libraries.<\/p>\n\n\n\n<p>In his ERC-funded project, Jordi van Gestel will study the coevolution between microbial predators and prey in the soil. Soil forms a hotspot of microbial predation: it contains a remarkable diversity of eukaryotic amoebal predators that feed on bacterial prey. Predation is thought to massively impact soil communities and hence soil function. So far, however, the way in which species coevolve in the context of predation is not well understood.&nbsp;<\/p>\n\n\n\n<p>\u201cWe will use the ERC grant to study how amoebae and bacteria coevolve in soil,\u201d said van Gestel. \u201cTo do so, we will systematically build complexity into our experimental set-ups. We will start by examining a predator-prey model system under fully controlled conditions in the lab. From there, we will then move to studying soil communities in the field.\u201d<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>How microbes and metabolites interact in the gut<\/strong><\/h2>\n\n\n\n<p><a href=\"https:\/\/www.embl.org\/groups\/zimmermann-kogadeeva\/\">Maria Zimmermann-Kogadeeva\u2019s group<\/a> combines computational modelling and multi-omics approaches to study how microbes interact with and adapt to the environment.&nbsp;<\/p>\n\n\n\n<p>The ERC grant will allow Zimmermann-Kogadeeva to study the mechanisms by which microbes in the gut interact with the host through metabolites \u2013 small molecules that can be exchanged between organisms. She will focus on a set of metabolites that are relevant for human health and have been associated with differences in microbiota composition. Through the project, she plans to combine bacterial culturing and metabolomics with computational modelling to systematically assess the capacity of gut bacteria to produce, modify, and exchange these metabolites.<\/p>\n\n\n\n<p>\u201cMetabolic interactions in gut microbial communities are known to have a role in human health and disease,\u201d explained Zimmermann-Kogadeeva. \u201cI\u2019m excited to use the generous ERC grant to further our understanding of the mechanistic principles of these interactions and hope that this will help to design future dietary and therapeutic interventions that modulate these interactions in order to improve human health and to prevent or treat diseases.\u201d<\/p>\n\n\n\n<p>Read the ERC announcement, including all awardees, on the <a href=\"https:\/\/erc.europa.eu\/news-events\/news\/erc-2023-starting-grants-results\">ERC website<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR funding for research projects on microbial predators and the gut microbiome respectively<\/p>\n","protected":false},"author":106,"featured_media":62001,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17597,3],"tags":[149,543,43,5776,233,13954,11942],"embl_taxonomy":[9796,18985,19423,19421],"class_list":["post-61919","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-embl-announcements","category-lab-matters","tag-award","tag-erc-grant","tag-heidelberg","tag-microbial-ecosystems","tag-microbiome","tag-van-gestel","tag-zimmermann-kogadeeva","embl_taxonomy-embl-heidelberg","embl_taxonomy-jordi-van-gestel","embl_taxonomy-van-gestel-group","embl_taxonomy-zimmermann-kogadeeva-group"],"acf":{"featured":true,"show_featured_image":false,"field_target_display":"embl","field_article_language":{"value":"english","label":"English"},"article_intro":"<p>Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR funding for research projects on microbial predators and the gut microbiome respectively<\/p>\n","related_links":[{"link_description":"EMBL ERC Investigators","link_url":"https:\/\/www.embl.org\/research\/faculty\/erc-investigators\/"},{"link_description":"van Gestel Group","link_url":"https:\/\/www.embl.org\/groups\/van-gestel\/"},{"link_description":"Welcome Jordi van Gestel ","link_url":"https:\/\/www.embl.org\/news\/lab-matters\/welcome-jordi-van-gestel\/"},{"link_description":"Developmental Biology Unit","link_url":"https:\/\/www.embl.org\/research\/units\/developmental-biology\/"},{"link_description":"Zimmermann-Kogadeeva Group","link_url":"https:\/\/www.embl.org\/groups\/zimmermann-kogadeeva\/"},{"link_description":"Welcome Maria Zimmermann-Kogadeeva","link_url":"https:\/\/www.embl.org\/news\/lab-matters\/welcome-maria-zimmermann-kogadeeva\/"},{"link_description":"Genome Biology Unit","link_url":"https:\/\/www.embl.org\/research\/units\/genome-biology\/"}],"source_article":false,"in_this_article":false,"press_contact":"None","article_translations":false,"languages":"","vf_locked":false},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"b14d3f13-5670-44fb-8970-e54dfd9c921a\";i:1;s:36:\"89e00fee-87f4-482e-a801-4c3548bb6a58\";i:2;s:36:\"ab46b6d4-71d8-49f8-b2f4-b326d4c8ea4e\";}","parents":[],"name":["EMBL Heidelberg"],"slug":"embl-heidelberg","description":"Where &gt; All EMBL sites &gt; EMBL Heidelberg"},{"uuid":"a:2:{i:0;s:36:\"4428d1fd-441a-4d6d-a1c5-5dcf5665f213\";i:1;s:36:\"28a9efaa-f72f-4091-b281-0dac48c90650\";}","parents":[],"name":["Jordi van Gestel"],"slug":"jordi-van-gestel","description":"Who &gt; Jordi van Gestel"},{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"6a2f2be6-8bb7-4425-b318-5ed992f715cc\";i:2;s:36:\"89454ab5-f7fb-4dc8-85cd-f0032253a1b1\";}","parents":[],"name":["van Gestel Group"],"slug":"van-gestel-group","description":"What &gt; Developmental Biology &gt; van Gestel Group"},{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"fe59a59f-fd7d-49b3-b3e4-bdd33a6642c3\";i:2;s:36:\"4a175694-19c4-47cb-b00e-32266d403437\";}","parents":[],"name":["Zimmermann-Kogadeeva Group"],"slug":"zimmermann-kogadeeva-group","description":"What &gt; Genome Biology &gt; Zimmermann-Kogadeeva Group"}],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ERC starting grants for two EMBL Heidelberg researchers | EMBL<\/title>\n<meta name=\"description\" content=\"Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR for research on microbial predators and the gut microbiome respectively\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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