{"id":52140,"date":"2022-09-07T12:00:00","date_gmt":"2022-09-07T10:00:00","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=52140"},"modified":"2025-11-19T12:53:26","modified_gmt":"2025-11-19T11:53:26","slug":"augmenting-science","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/lab-matters\/augmenting-science\/","title":{"rendered":"Augmenting science"},"content":{"rendered":"\n

In Spain, Brais Bea-Mascato had used a gene editing tool to reproduce two rare and complex genetic disorders \u2013 Alstr\u00f6m syndrome and Bardet-Biedl syndrome \u2013 in normal cultured cells. Using various omics technologies, he hopes to shed light on the alterations that ultimately lead to disease progression. But, this had generated a wealth of hard-to-understand data.<\/p>\n\n\n\n

In Greece, Virginia Fasoulaki was wrestling with challenges in her PhD research that explored the adaptability of intestinal stem cells in fruit flies (Drosophila melanogaster<\/em>). She was interested in unravelling the epigenetic variations that control the role these particular stem cells ultimately play. But she needed expertise in state-of-the-art genomics approaches that can use very low-input samples to do her experiments.<\/p>\n\n\n\n

In both of these cases, a short stint at EMBL, working with its world-class researchers and tools, proved to be just the thing to move past research obstacles. Even in a relatively short time, Bea-Mascato and Fasoulaki could obtain the necessary skills and knowledge.  And thanks to EMBL\u2019s Corporate Partnership Program<\/a>me (CPP) and the Friends of EMBL, they received support that made a visit to EMBL possible through EMBL\u2019s Scientific Visitor Programme<\/a>.<\/p>\n\n\n\n

\u201cWe\u2019ve seen again and again how the Scientific Visitor Programme can really boost young researchers\u2019 work with the access they gain to EMBL\u2019s state-of-the-art technology platforms and associated expertise at all of EMBL\u2019s sites,\u201d said Claudia Martin, EMBL Visitor Programme Manager. \u201cThey get first-rate training and support that usually exceeds the boundaries of their stay at EMBL.\u201d<\/p>\n\n\n\n

For Fasoulaki, it meant learning a technique known as transposase-based CUT & Tag in the Furlong group<\/a>. This technique, in addition to follow-on bioinformatics training, will enable her to measure changes in chromatin states in stem cells after different mutations, and it equips her to analyse the resulting data.<\/p>\n\n\n\n

\u201cThe Furlong lab has emerged as one of the top groups internationally in chromatin biology and has pioneered many approaches in Drosophila<\/em>,\u201d she said. \u201cTheir expertise in CUT & Tag profiling, in combination with EMBL\u2019s top-notch core facilities, is now enabling me to carry out my proposed experiments and get my PhD project one step further.\u201d<\/p>\n\n\n\n

\"Head
Brais Bea-Mascato is back in Spain after three months at EMBL-EBI where he acquired new bioinformatic skills needed for his PhD research. Credit: Brais Bea-Mascato<\/figcaption><\/figure>\n\n\n\n

Likewise, Bea-Mascato found his research world expanded too, through preliminary discussions with the Petsalaki group<\/a> at EMBL-EBI, which works on deciphering cell signalling. Upon visiting the Petsalaki lab, he was introduced to new techniques, such as semantic similarity and network propagation. The result was a fast-paced, hands-on, and practical bioinformatics training that he could apply to his own research.<\/p>\n\n\n\n

\u201cWith mostly wet-lab experience and a lack of researchers doing similar experiments at my own university, I knew data analysis would be challenging without expert help. From day one, Evangelia Petsalaki was tremendously open-minded and helpful,\u201d he said. \u201cI have come to understand that omics technologies provide increasing accuracy and decreasing costs for proper data analysis, an important challenge in modern biology. It\u2019s also something I would love to work on in the future. This requires developing a kind of logic and way of thinking that this stay allowed me to develop.\u201d<\/p>\n\n\n\n

And this is the kind of growth that EMBL had envisioned with its visitor programme. Though these most recent EMBL visiting scientists were working on their PhDs, the programme also includes postdoctoral fellows in EMBL\u2019s collaborative and multidisciplinary scientific atmosphere.<\/p>\n\n\n\n

“The support allows young scientists to join EMBL and work on short- to medium-term projects in a collaborative, multidisciplinary scientific atmosphere,\u201d said J\u00fcrgen Deka, Head of External Scientific Training.<\/p>\n\n\n\n

Additionally, thanks to support from EMBL\u2019s CPP and the Friends of EMBL, EMBL can defray some costs associated with travel and housing for participants who otherwise would not have been able to afford this experience. Friends of EMBL is a network for anyone interested in life sciences, and in supporting EMBL’s research and missions.<\/p>\n\n\n\n

The CPP fellowships programme accepts applications four times per year. Applicants start the process by reaching out to EMBL scientists who they believe will be best suited to consult with them on their research and take it to the next level. Acceptance is always dependent on mutual interest shared with the EMBL host.<\/p>\n\n\n\n

Founded in 2009, CPP primarily promotes and facilitates exchange and cooperation at the frontier of science between leaders from industry, EMBL\u2018s research community, and world-leading scientific facilities. Currently, 21 companies are part of the programme and contribute to EMBL\u2019s training mission. CPP fellowships for scientific visitors support the collaboration of young external researchers and EMBL groups by offering financial support of up to \u20ac2,000 per applicant and are designed to enable the mobility of PhD students and postdocs to access EMBL\u2019s sites. Preference is given to cases that support cross-border mobility to encourage greatest participation from EMBL member states.  However, recipients have also come from other countries.<\/p>\n\n\n\n

\u201cThe agility and speed with which the selection process for this fellowship was carried out were among its greatest virtues,\u201d Bea-Mascato said. \u201cBeing selected for a grant that allowed money to be available during the stay was a financial relief that undoubtedly allowed me to focus on the science I wanted to develop at EMBL-EBI.\u201d<\/p>\n\n\n\n

\u201cWhat prompted me to apply for this fellowship was that there are no restrictions on scientific background, country of origin, or personal states. Plus, they hold selection rounds every three months, and the application is really easy to submit,\u201d Fasoulaki offered. \u201cIn my case, EMBL funding not only supported my travel and a big part of the accommodation costs, it enabled me to prolong my visit.\u201d<\/p>\n\n\n\n

Applications are accepted at the end of each quarter, and interested scientists from other organisations, and who have an EMBL host, are encouraged to apply.  The next application deadline is 30 September. \u201cIt\u2019s been great to interact with innovative researchers from all over the world that make up EMBL\u2019s scientific community,\u201d Fasoulaki said.  \u201cI have broadened my research horizons and enhanced my scientific research long term. With EMBL\u2019s renowned expertise in genomics, I think this was the right place for me to be!\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

The Scientific Visitor Programme shares EMBL tools and talent with outside researchers in collaborative, multidisciplinary environments.<\/p>\n","protected":false},"author":100,"featured_media":52146,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3],"tags":[172,270,13680,12754,123,996,5100,13072,27],"embl_taxonomy":[19535,1802,4798,5172,5802],"class_list":["post-52140","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lab-matters","tag-corporate-partnership-programme","tag-friends-of-embl","tag-greece","tag-international-collaboration","tag-member-state","tag-scientific-visitor-programme","tag-spain","tag-support-embl","tag-training","embl_taxonomy-corporate-partnership-programme","embl_taxonomy-institutional-collaborations","embl_taxonomy-international-relations","embl_taxonomy-scientific-visitor-programme","embl_taxonomy-support-embl"],"acf":{"featured":true,"show_featured_image":false,"field_target_display":"embl","field_article_language":{"value":"english","label":"English"},"article_intro":"

EMBL\u2019s Visitor Programme offers top-of-the-line access to research expertise and tools, taking science projects to new levels<\/p>\n","related_links":[{"link_description":"EMBL Scientific Visitor Programme ","link_url":"https:\/\/www.embl.org\/about\/info\/scientific-visitor-programme\/"},{"link_description":"EMBL Corporate Partnership Programme ","link_url":"https:\/\/www.embl.org\/about\/info\/support\/embl-corporate-partnership-programme\/"},{"link_description":"Friends of EMBL Programme ","link_url":"https:\/\/www.embl.org\/about\/info\/support\/join-the-friends-of-embl\/"}],"source_article":false,"in_this_article":false,"press_contact":"None","article_translations":false,"languages":"","vf_locked":false,"vfwp-news_embl_taxonomy":[1802,4798,5172,5802,19535]},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"69e1d012-360d-4754-bf0f-9e1185643e9f\";i:2;s:36:\"0d3270ca-455c-428a-86f4-c61b1de8c3e0\";}","parents":[],"name":["Corporate 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