{"id":4850,"date":"2015-08-24T15:59:57","date_gmt":"2015-08-24T13:59:57","guid":{"rendered":"http:\/\/news.embl.de\/?p=4850"},"modified":"2024-04-19T15:18:56","modified_gmt":"2024-04-19T13:18:56","slug":"1508_vaccari","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/","title":{"rendered":"Cellular synergy"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\">What are you working on?<\/h3>\n\n\n\n<p>Our lab is interested in understanding how vesicles going to and from the cell\u2019s \u2018digestive factories\u2019, lysosomes and endosomes, contribute to intracellular signalling, in both health and disease \u2013 for example in tissue and organ development or in cancer. In my talk, I discussed our recent findings on molecules that mediate these processes and how they could influence cell division and potentially cancer \u2013 an exciting observation that has inspired us to venture into a completely new field.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Which areas of research during the conference did you find particularly interesting?<\/h3>\n\n\n\n<p>There were some fantastic talks on a wide range of areas such as epigenetics, cell cycle control and cell plasticity. I really appreciated the work presented by <a href=\"http:\/\/www.embl.de\/research\/units\/cbb\/jechlinger\/members\/index.php?s_personId=CP-60011737\">Martin Jechlinger<\/a> and<a href=\"http:\/\/www.embl.it\/research\/unit\/sotillo\/members\/index.php?s_personId=CP-60011933\"> Rocio Sotillo<\/a>, which mirrored some of our interests in cancer studies. I also loved the talk by Cornelius Gross \u2013 his research has a distinctly different focus to ours, but he presented a wonderfully elegant approach to studying fear, which is such an intricate and elusive subject.<\/p>\n\n\n\n<blockquote class=\"vf-blockquote\"><p>Cornelius Gross&nbsp;presented a wonderfully elegant approach to studying fear, which is such an intricate and elusive subject.<\/p><\/blockquote>\n\n\n\n<h3 class=\"wp-block-heading\">How did you first become interested in cell biology?<\/h3>\n\n\n\n<p>My interests originated at EMBL Heidelberg, where I did my PhD in <a href=\"http:\/\/www.embl.de\/research\/units\/dev_biology\/members\/index.php?s_personId=CP-60003271\">Anne Ephrussi<\/a>\u2019s group, studying how certain molecules within developing <em>Drosophila<\/em> oocytes migrate to specific regions, thus controlling the development of the fly\u2019s body. Anne was a great mentor, and I have fond memories working in her team. Not only did I have a terrific formal training and access to a global web of contacts, but working at EMBL instilled in me a deep love and wonder for science and discovery that still drives me today.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What do you think the future holds for the field?<\/h3>\n\n\n\n<p>We are on the way to understanding how amazingly adaptable the cell\u2019s endosomes and lysosomes are to the environment and the specific needs of the cell. Cells in the gut, kidneys, immune cells and skin cells are hugely creative in how they use their machinery, and crucially we will begin to understand how such processes are hijacked in several types of cancer.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.<\/p>\n","protected":false},"author":28,"featured_media":4851,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4,17593],"tags":[80,64,357,92,74,514],"embl_taxonomy":[],"class_list":["post-4850","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-events","category-people-perspectives","tag-alumni","tag-cell-biology","tag-ephrussi","tag-event","tag-monterotondo","tag-rome"],"acf":{"article_intro":"<p>Combining synergies, science and shared visions, experts from <a href=\"http:\/\/www.embl.it\/\" target=\"_blank\">EMBL Monterotondo<\/a> and the Institute for Molecular Oncology (IFOM) came together for their first joint symposium, 29\u201330 June in Milan. Focussing on cell biology mechanisms in health and disease, the two-day conference included an extensive programme of presentations, networking and exchange. We caught up with alumnus Thomas Vaccari, now a principal investigator at IFOM, who was a speaker at the event.<\/p>\n","related_links":[{"link_description":"EMBL Montertondo seminars calendar","link_url":"http:\/\/www.embl.it\/research\/seminars\/index.php"},{"link_description":" Institute for Molecular Oncology (IFOM) ","link_url":"https:\/\/www.ifom.eu\/en\/"}],"article_sources":false,"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cellular synergy | EMBL<\/title>\n<meta name=\"description\" content=\"Alumnus Thomas Vaccari&#039;s input on the first EMBL-IFOM joint symposium, on cell biology mechanisms in health and disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cellular synergy | EMBL\" \/>\n<meta property=\"og:description\" content=\"Alumnus Thomas Vaccari&#039;s input on the first EMBL-IFOM joint symposium, on cell biology mechanisms in health and disease.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2015-08-24T13:59:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-19T13:18:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2015\/08\/cellularsynergy.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Jos\u00e9 Viosca\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@jviosca\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jos\u00e9 Viosca\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/\"},\"author\":{\"name\":\"Jos\u00e9 Viosca\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/09e8fef149161aed0f9562a51f714c36\"},\"headline\":\"Cellular synergy\",\"datePublished\":\"2015-08-24T13:59:57+00:00\",\"dateModified\":\"2024-04-19T13:18:56+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/\"},\"wordCount\":362,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/events\/1508_vaccari\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2015\/08\/cellularsynergy.jpg\",\"keywords\":[\"alumni\",\"cell biology\",\"ephrussi\",\"event\",\"monterotondo\",\"rome\"],\"articleSection\":[\"Events\",\"People &amp; 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