{"id":4719,"date":"2015-08-06T12:24:14","date_gmt":"2015-08-06T10:24:14","guid":{"rendered":"http:\/\/news.embl.de\/?p=4719"},"modified":"2024-04-19T15:27:31","modified_gmt":"2024-04-19T13:27:31","slug":"1508-alexandrov","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/","title":{"rendered":"Welcome: Theodore Alexandrov"},"content":{"rendered":"\n<p>The <a href=\"http:\/\/www.embl.de\/research\/units\/scb\/alexandrov\/\" target=\"_blank\" rel=\"noopener noreferrer\">Alexandrov Team<\/a> aims to bridge computer science and biology, by providing tools that reveal where different chemical reactions take place within a cell, tissue or an organism. The team\u2019s two flagship projects are the molecular cartography of the human skin surface, and the molecular annotation of high-resolution imaging mass spectrometry data.<\/p>\n\n\n\n<blockquote class=\"vf-blockquote\"><p>I started transforming my maths so that it could accept these new types of data, and then I just got sucked in\u2026<\/p><\/blockquote>\n\n\n\n<h3 class=\"wp-block-heading\">How did you move from mathematician to biologist?<\/h3>\n\n\n\n<p>The move to the life sciences was a big change. I came to Germany for a postdoc to work on an econometrics project. In Bremen, I was doing a time-series analysis, predicting the number of bank transactions for MasterCard. I was approached by a manager of one of the largest mass spectrometry vendors, who said: \u201cI see you\u2019re dealing with something that looks sort of similar to our data \u2013 can you do some machine learning and statistics on this?\u201d So I started transforming my maths so that it could accept these new types of data, and then I just got sucked into mass spectrometry, then imaging mass spectrometry, then metabolomics \u2026<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Name one tool you can\u2019t do without<\/h3>\n\n\n\n<p>Oh, definitely a computer. I started programming pretty late, compared to my peers \u2013 at about 15 years old. Someone gave me a computer and I was amazed; I\u2019m still amazed. It\u2019s like magic: you can implement your thoughts into something almost material. You start coding, you type things, and then, for example, you have this beautiful software that can rotate something or plot something. Carrying a computer is like having a bit of magic on your lap, because it\u2019s instantaneous: people can see your thoughts in minutes.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Whose work at EMBL intrigues you? Do you already have potential collaborators in mind?<\/h3>\n\n\n\n<p>Yeah, many people! Before I joined I wrote a shortlist, partly to show that I could be integrated \u2013 something everyone should do when applying for a group leader position \u2013 but also because there are lots of scientists here doing fascinating science; I think I\u2019d be happy collaborating with everyone! That\u2019s why, when there are opportunities I jump on them, resources permitting. It\u2019s a very cool environment: you get empowered, and we empower each other in these collaborations.<\/p>\n\n\n\n<blockquote class=\"vf-blockquote\"><p>The group should be interdisciplinary, it should be small, and every person should be independent and excellent in some way.<\/p><\/blockquote>\n\n\n\n<h3 class=\"wp-block-heading\">What is your philosophy for running your lab?<\/h3>\n\n\n\n<p>I don\u2019t know whether it\u2019s a philosophy as such, but I\u2019m trying first of all to make everyone equal. There is no difference whether you\u2019re a master\u2019s student, a staff researcher, a postdoc \u2013 everyone contributes. I\u2019m also trying to create an environment that fosters group members, not directs them. As a boss, you provide the environment and the infrastructure, and then you see what comes out.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">What will you be looking for as you build your group?<\/h3>\n\n\n\n<p>I would like to have a small but interdisciplinary team \u2013 already, we have people from cell biology, theoretical computer science, analytical chemistry, and software development, including someone who helped to develop Google Chrome. They are benefiting a lot from talking to each other. So, the group should be interdisciplinary, it should be small, and every person should be independent and excellent in some way.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If there was a motto hanging at your lab\u2019s door, what would it be?<\/h3>\n\n\n\n<p>Hmm, I don\u2019t have a motto all thought out, but I can give you some keywords that would definitely be in it: I highly value \u2018openness\u2019; I like to act as a mediator across a wide range of expertise, so \u2018interdisciplinarity\u2019 \u2013 while much over-used \u2013 is key; \u2018motivation\u2019 would have to be in there, too, as I try to achieve things by getting people motivated. Finally, our overall aim is \u2018data translation\u2019: translating data \u2013 numbers, letters, documents, results \u2013 into something useful by crunching numbers, connecting dots, finding something never observed before, and representing it so that biologists and chemists will see things anew.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Where do you come from? What are the best things about science in your country?<\/h3>\n\n\n\n<p>Science has a strong tradition in Russia. It stems from imperial times, and was intensified in the Soviet era. There was a culture of science \u2013 to be a scientist was a well-regarded profession. Nowadays, theoretical science is still really good, especially technical sciences like mathematics. Sometimes when I say where I come from \u2013 \u201cI\u2019m from St. Petersburg, and I got a PhD there in mathematics&#8221; \u2013 everyone is like \u2018ooh!\u2019.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A mathematician who got \u2018sucked in\u2019 to biological problems, meet new team leader Theodore Alexandrov.<\/p>\n","protected":false},"author":8,"featured_media":4724,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17593,2],"tags":[28,59,43,219,35,295],"embl_taxonomy":[],"class_list":["post-4719","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-people-perspectives","category-science","tag-bioinformatics","tag-careers","tag-heidelberg","tag-metabolomics","tag-structural-biology","tag-welcome"],"acf":{"article_intro":"<p>A mathematician who got \u2018sucked in\u2019 to biological problems, new team leader Theodore Alexandrov will draw on everything from cryptography to software development to help biologists and chemists see data in a new light.<\/p>\n","related_links":false,"article_sources":false,"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Welcome: Theodore Alexandrov | EMBL<\/title>\n<meta name=\"description\" content=\"A mathematician who got \u2018sucked in\u2019 to biological problems, meet new team leader Theodore Alexandrov.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Welcome: Theodore Alexandrov | EMBL\" \/>\n<meta property=\"og:description\" content=\"A mathematician who got \u2018sucked in\u2019 to biological problems, meet new team leader Theodore Alexandrov.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2015-08-06T10:24:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-04-19T13:27:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2015\/08\/1508-Alexandrov-ib.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Sonia Furtado Neves\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@Aur_ora\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sonia Furtado Neves\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/\"},\"author\":{\"name\":\"Sonia Furtado Neves\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/d926199a955624b44dda296f396c5e68\"},\"headline\":\"Welcome: Theodore Alexandrov\",\"datePublished\":\"2015-08-06T10:24:14+00:00\",\"dateModified\":\"2024-04-19T13:27:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/\"},\"wordCount\":766,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1508-alexandrov\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2015\/08\/1508-Alexandrov-ib.jpg\",\"keywords\":[\"bioinformatics\",\"careers\",\"heidelberg\",\"metabolomics\",\"structural biology\",\"welcome\"],\"articleSection\":[\"People &amp; 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