{"id":45486,"date":"2021-12-17T10:32:22","date_gmt":"2021-12-17T09:32:22","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=45486"},"modified":"2024-03-22T15:19:09","modified_gmt":"2024-03-22T14:19:09","slug":"ai-protein-prediction-breakthrough","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/","title":{"rendered":"Artificial intelligence \u2014 a scientific game changer in 2021"},"content":{"rendered":"\n<p>From shortening the time for <a href=\"https:\/\/www.embl.org\/news\/science\/artificial-intelligence-makes-great-microscopes-better-than-ever\/\">image processing in light-field microscopy<\/a> from days to mere seconds to <a href=\"https:\/\/www.embl.org\/news\/science\/alphafold-protein-structure\/\">predicting the 3D structure<\/a> of a protein from its amino acid sequence \u2014 artificial intelligence (AI) has transformed the way life scientists conduct research.<\/p>\n\n\n\n<p>The prediction of the structures of the human proteome using DeepMind\u2019s AI-driven AlphaFold algorithm is one of the biggest scientific breakthroughs since the mapping of the human genome.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.embl.org\/news\/science\/alphafold-database-launch\/\">DeepMind and EMBL\u2019s European Bioinformatics Institute (EMBL-EBI)<\/a>&nbsp;are providing access to&nbsp;AlphaFold\u2019s&nbsp;predictions <a href=\"http:\/\/www.alphafold.ebi.ac.uk\/\">in a database<\/a>&nbsp;so&nbsp;scientists all over the world can use the system as a tool to enable and accelerate research and open up completely new avenues of scientific discovery.&nbsp;Making&nbsp;the&nbsp;data&nbsp;of protein predictions&nbsp;freely and openly available to the scientific community accelerates the&nbsp;impact&nbsp;of this technology.<\/p>\n\n\n\n<p>Accurately predicting the structure of proteins has the potential to accelerate discovery in relation to a range of scientific applications, e.g. in developing new drugs and treatments for diseases, in designing future crops that can withstand climate change or in developing enzymes that can degrade plastic.<\/p>\n\n\n\n<p>Compared with the time of its launch in July 2021, the <a href=\"http:\/\/www.alphafold.ebi.ac.uk\/\">AlphaFold database<\/a> already contains double the number of protein predictions, which have been accessed by more than 310K unique users. With millions of protein structure predictions available in the future, <a href=\"https:\/\/www.embl.org\/news\/science\/alphafold-potential-impacts\/\">the possibilities for discoveries seem endless.<\/a><\/p>\n\n\n\n<p>After having already been referred to as one of the <a href=\"https:\/\/www.nature.com\/articles\/d41586-021-03734-6\">most influential scientific developments in 2021<\/a> by <em>Nature<\/em> magazine, the impact that AI had on protein structure prediction was now also recognised as <a href=\"https:\/\/www.science.org\/content\/article\/breakthrough-2021?utm_campaign=SciMag&amp;utm_source=Social&amp;utm_medium=Twitter\">2021 \u2018Breakthrough of the Year\u2019<\/a> by <em>Science<\/em> magazine. It also topped the magazine\u2019s \u2018People\u2019s Choice\u2019 poll.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named &#8216;2021 Breakthrough of the Year&#8217; by Science magazine.<\/p>\n","protected":false},"author":114,"featured_media":45496,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,17591],"tags":[12758,4718,28,5088,5752,35],"embl_taxonomy":[2906],"class_list":["post-45486","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-science-technology","tag-alphafold","tag-artificial-intelligence","tag-bioinformatics","tag-deep-learning","tag-protein-structure","tag-structural-biology","embl_taxonomy-embl-ebi"],"acf":{"featured":true,"show_featured_image":false,"field_target_display":"","article_intro":"<p>The ability to predict protein structures from amino acid sequences using AI named as 2021 &#8216;Breakthrough of the Year&#8217; by <em>Science<\/em> magazine<\/p>\n","related_links":[{"link_description":"AlphaFold Protein Structure Database","link_url":"http:\/\/www.alphafold.ebi.ac.uk\/"},{"link_description":"DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins","link_url":"https:\/\/www.embl.org\/news\/science\/alphafold-database-launch\/"},{"link_description":"AlphaFold's potential impact ","link_url":"https:\/\/www.embl.org\/news\/science\/alphafold-potential-impacts\/"},{"link_description":"Image processing in light-field microscopy","link_url":"https:\/\/www.embl.org\/news\/science\/artificial-intelligence-makes-great-microscopes-better-than-ever\/"}],"source_article":false,"in_this_article":false,"press_contact":"None","field_article_language":{"value":"english","label":"English"},"article_translations":false,"languages":""},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"b14d3f13-5670-44fb-8970-e54dfd9c921a\";i:1;s:36:\"89e00fee-87f4-482e-a801-4c3548bb6a58\";i:2;s:36:\"a99d1a7c-ca83-4c00-ab61-d082d3e41ce3\";}","parents":[],"name":["EMBL-EBI"],"slug":"embl-ebi","description":"Where &gt; All EMBL sites &gt; EMBL-EBI"}],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Artificial intelligence \u2014 a scientific game changer in 2021 | EMBL<\/title>\n<meta name=\"description\" content=\"The ability to predict protein structures from amino acid sequences using AI named 2021 \u2018Breakthrough of the Year&#039; by Science magazine\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Artificial intelligence \u2014 a scientific game changer in 2021 | EMBL\" \/>\n<meta property=\"og:description\" content=\"The ability to predict protein structures from amino acid sequences using AI named 2021 \u2018Breakthrough of the Year&#039; by Science magazine\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-12-17T09:32:22+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T14:19:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2021\/12\/211216_AlphaFold_Science-announcement_wp.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Lisa Vollmar\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Lisa Vollmar\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/\"},\"author\":{\"name\":\"Lisa Vollmar\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/cdb35218b2c7e9143b216cb18c74d6c6\"},\"headline\":\"Artificial intelligence \u2014 a scientific game changer in 2021\",\"datePublished\":\"2021-12-17T09:32:22+00:00\",\"dateModified\":\"2024-03-22T14:19:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/\"},\"wordCount\":294,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/ai-protein-prediction-breakthrough\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2021\/12\/211216_AlphaFold_Science-announcement_wp.jpg\",\"keywords\":[\"alphafold\",\"artificial intelligence\",\"bioinformatics\",\"deep learning\",\"protein structure\",\"structural biology\"],\"articleSection\":[\"Science\",\"Science &amp; 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