{"id":39192,"date":"2021-06-15T10:00:00","date_gmt":"2021-06-15T08:00:00","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=39192"},"modified":"2024-03-22T11:16:17","modified_gmt":"2024-03-22T10:16:17","slug":"potw2122","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/","title":{"rendered":"Twinkle, twinkle, little nuclear pore complex"},"content":{"rendered":"\n<p>Rather than looking out into the great beyond on a starry, starry night, this image comes from deep within our human cellular universe.&nbsp;<\/p>\n\n\n\n<p>These numerous twinkling objects are actually part of a super-resolution image of nuclear pore complexes (NPCs) in the cell. NPCs are assemblies of proteins that create channels in the membrane surrounding the nucleus. They regulate the transport of molecules between the nucleus and the rest of the cell.<\/p>\n\n\n\n<p>To capture this sparkling image, scientists in the <a href=\"https:\/\/www.embl.org\/groups\/ries\/\">Ries group<\/a> designed and built a customised super-resolution microscope in their lab. They fluorescently labelled a nuclear pore protein called Nup96 (red) and the central channel of the nuclear pore complex (cyan) using a molecule called wheat germ agglutinin. Members of the Ries group use samples like these to optimise their microscopes for further use. Not a bad view.<\/p>\n\n\n\n<p>Credit: Jervis Thevathasan &amp; Maurice Kahnwald\/EMBL<\/p>\n\n\n\n<p>If you have a stunning picture of your science, your lab or your site, you can&nbsp;<a target=\"_blank\" href=\"mailto:media@embl.org\" rel=\"noreferrer noopener\">submit it by email<\/a>.&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>As perfect as a summer night sky, these nuclear pores help calibrate a customised super-resolution microscope in EMBL\u2019s Ries group.<\/p>\n","protected":false},"author":100,"featured_media":39448,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,17591],"tags":[1012,43,1790,704,9992,11022],"embl_taxonomy":[19363],"class_list":["post-39192","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-picture-of-the-week","category-science-technology","tag-fluorescence-microscopy","tag-heidelberg","tag-nuclear-pore","tag-proteins","tag-ries","tag-spotlight","embl_taxonomy-ries-group-visiting"],"acf":{"featured":false,"show_featured_image":false,"color":"#007B53","link_color":"#fff","article_intro":"","related_links":false,"article_sources":false,"in_this_article":false,"youtube_url":"","mp4_url":"","video_caption":"","press_contact":"None","source_article":false,"vf_locked":false,"field_target_display":"embl"},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"64999cc4-9a7c-4fea-8339-0e2acc990e08\";i:2;s:36:\"685f39f1-defb-4bd8-bad0-ef386025ee87\";}","parents":[],"name":["Ries Group (Visiting)"],"slug":"ries-group-visiting","description":"What &gt; Cell biology and biophysics &gt; Ries Group (Visiting)","deprecated":true}],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Twinkle, twinkle, little nuclear pore complex | EMBL<\/title>\n<meta name=\"description\" content=\"As perfect as a summer night sky, these nuclear pores help calibrate a customised super-resolution microscope in EMBL\u2019s Ries group.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Twinkle, twinkle, little nuclear pore complex | EMBL\" \/>\n<meta property=\"og:description\" content=\"As perfect as a summer night sky, these nuclear pores help calibrate a customised super-resolution microscope in EMBL\u2019s Ries group.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-15T08:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T10:16:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2021\/06\/PotW-NPC-wp.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ivy Kupec\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ivy Kupec\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/\"},\"author\":{\"name\":\"Ivy Kupec\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/427f2c9b624bc32ffa67d80414712274\"},\"headline\":\"Twinkle, twinkle, little nuclear pore complex\",\"datePublished\":\"2021-06-15T08:00:00+00:00\",\"dateModified\":\"2024-03-22T10:16:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/\"},\"wordCount\":174,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2122\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2021\/06\/PotW-NPC-wp.jpg\",\"keywords\":[\"fluorescence microscopy\",\"heidelberg\",\"nuclear pore complex\",\"proteins\",\"ries\",\"spotlight\"],\"articleSection\":[\"Picture of the week\",\"Science &amp; 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