{"id":33794,"date":"2020-11-24T09:00:18","date_gmt":"2020-11-24T08:00:18","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=33794"},"modified":"2024-03-22T11:14:37","modified_gmt":"2024-03-22T10:14:37","slug":"potw2047","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/","title":{"rendered":"A loopy baseline"},"content":{"rendered":"\n<p>Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.<\/p>\n\n\n\n<p>This beautiful image comes from a confocal microscope, which captured the CD90 protein (shown in red) that marks the surface of these cells. Researchers from EMBL\u2019s Zaugg group study leukaemia onset and were looking to see whether CD90 would be an effective marker to identify MSCs in bone marrow.<\/p>\n\n\n\n<p>Targeting the microenvironment of leukaemic cells, in this case MSCs, can result in novel leukaemia therapies. Images like this can serve as a baseline for further research to study them in the context of leukaemia.<\/p>\n\n\n\n<p>Leukaemia is a cancer of the blood and bone marrow, and these scientists are studying the most prevalent types of leukaemia that tend to strike between the ages of 65 and 74.&nbsp;<\/p>\n\n\n\n<p>Credit: Anna Mathioudaki\/EMBL<\/p>\n\n\n\n<p>If you have a stunning picture of your science, your lab or your site, you can submit it <a href=\"mailto:mathias.jaeger@embl.de\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.<\/p>\n","protected":false},"author":100,"featured_media":33796,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,17591],"tags":[38,883,1306,11022],"embl_taxonomy":[9796,18991,19413],"class_list":["post-33794","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-picture-of-the-week","category-science-technology","tag-cancer","tag-cell","tag-leukaemia","tag-spotlight","embl_taxonomy-embl-heidelberg","embl_taxonomy-judith-zaugg","embl_taxonomy-zaugg-group"],"acf":{"embl_taxonomy_term_who":1619,"embl_taxonomy_term_what":1094,"embl_taxonomy_term_where":3138,"featured":false,"show_featured_image":false,"color":"#007B53","link_color":"#fff","article_intro":"","related_links":false,"article_sources":false,"in_this_article":false,"youtube_url":"","mp4_url":"","video_caption":"","press_contact":"None","translations":false,"vf_locked":false},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"b14d3f13-5670-44fb-8970-e54dfd9c921a\";i:1;s:36:\"89e00fee-87f4-482e-a801-4c3548bb6a58\";i:2;s:36:\"ab46b6d4-71d8-49f8-b2f4-b326d4c8ea4e\";}","parents":[],"name":["EMBL Heidelberg"],"slug":"embl-heidelberg","description":"Where &gt; All EMBL sites &gt; EMBL Heidelberg"},{"uuid":"a:2:{i:0;s:36:\"4428d1fd-441a-4d6d-a1c5-5dcf5665f213\";i:1;s:36:\"339c21ad-c21e-478f-aeed-c8e2903c172b\";}","parents":[],"name":["Judith Zaugg"],"slug":"judith-zaugg","description":"Who &gt; Judith Zaugg"},{"uuid":"a:3:{i:0;s:36:\"302cfdf7-365b-462a-be65-82c7b783ebf7\";i:1;s:36:\"bd910dd7-0cda-4618-8bfa-d37fbda8438e\";i:2;s:36:\"1da41039-0c1d-4543-9cc5-7da2b51266f6\";}","parents":[],"name":["Zaugg Group"],"slug":"zaugg-group","description":"What &gt; Molecular Systems Biology &gt; Zaugg Group"}],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>A loopy baseline | EMBL<\/title>\n<meta name=\"description\" content=\"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A loopy baseline | EMBL\" \/>\n<meta property=\"og:description\" content=\"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-11-24T08:00:18+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T10:14:37+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Ivy Kupec\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Ivy Kupec\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\"},\"author\":{\"name\":\"Ivy Kupec\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/427f2c9b624bc32ffa67d80414712274\"},\"headline\":\"A loopy baseline\",\"datePublished\":\"2020-11-24T08:00:18+00:00\",\"dateModified\":\"2024-03-22T10:14:37+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\"},\"wordCount\":167,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg\",\"keywords\":[\"cancer\",\"cell\",\"leukaemia\",\"spotlight\"],\"articleSection\":[\"Picture of the week\",\"Science &amp; Technology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\",\"url\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\",\"name\":\"A loopy baseline | EMBL\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg\",\"datePublished\":\"2020-11-24T08:00:18+00:00\",\"dateModified\":\"2024-03-22T10:14:37+00:00\",\"description\":\"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg\",\"width\":1000,\"height\":600,\"caption\":\"Mesenchymal stromal cells from healthy bone marrow are central to better understanding leukemia onset. This image, illustrating the cells\u2019 loopy morphology, was captured by EMBL\u2019s Zaugg group. Credit: Anna Mathioudaki\/EMBL\"},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.embl.org\/news\/#website\",\"url\":\"https:\/\/www.embl.org\/news\/\",\"name\":\"European Molecular Biology Laboratory News\",\"description\":\"News from the European Molecular Biology Laboratory\",\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"alternateName\":\"EMBL News\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.embl.org\/news\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.embl.org\/news\/#organization\",\"name\":\"European Molecular Biology Laboratory\",\"alternateName\":\"EMBL\",\"url\":\"https:\/\/www.embl.org\/news\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png\",\"width\":300,\"height\":144,\"caption\":\"European Molecular Biology Laboratory\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/embl.org\/\",\"https:\/\/x.com\/embl\",\"https:\/\/www.instagram.com\/embl_org\/\",\"https:\/\/www.linkedin.com\/company\/15813\/\",\"https:\/\/www.youtube.com\/user\/emblmedia\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/427f2c9b624bc32ffa67d80414712274\",\"name\":\"Ivy Kupec\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/1abc86f00519d61bc0f2793ed624175c2d7ad829fb5b60e1c3b99a973ac351a6?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/1abc86f00519d61bc0f2793ed624175c2d7ad829fb5b60e1c3b99a973ac351a6?s=96&d=mm&r=g\",\"caption\":\"Ivy Kupec\"},\"url\":\"https:\/\/www.embl.org\/news\/author\/ivy-kupecembl-de\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"A loopy baseline | EMBL","description":"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/","og_locale":"en_US","og_type":"article","og_title":"A loopy baseline | EMBL","og_description":"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.","og_url":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/","og_site_name":"EMBL","article_publisher":"https:\/\/www.facebook.com\/embl.org\/","article_published_time":"2020-11-24T08:00:18+00:00","article_modified_time":"2024-03-22T10:14:37+00:00","og_image":[{"width":1000,"height":600,"url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","type":"image\/jpeg"}],"author":"Ivy Kupec","twitter_card":"summary_large_image","twitter_creator":"@embl","twitter_site":"@embl","twitter_misc":{"Written by":"Ivy Kupec","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"NewsArticle","@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#article","isPartOf":{"@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/"},"author":{"name":"Ivy Kupec","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/427f2c9b624bc32ffa67d80414712274"},"headline":"A loopy baseline","datePublished":"2020-11-24T08:00:18+00:00","dateModified":"2024-03-22T10:14:37+00:00","mainEntityOfPage":{"@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/"},"wordCount":167,"publisher":{"@id":"https:\/\/www.embl.org\/news\/#organization"},"image":{"@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage"},"thumbnailUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","keywords":["cancer","cell","leukaemia","spotlight"],"articleSection":["Picture of the week","Science &amp; Technology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/","url":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/","name":"A loopy baseline | EMBL","isPartOf":{"@id":"https:\/\/www.embl.org\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage"},"image":{"@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage"},"thumbnailUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","datePublished":"2020-11-24T08:00:18+00:00","dateModified":"2024-03-22T10:14:37+00:00","description":"Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit \u2018loopy\u2019.","inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2047\/#primaryimage","url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","contentUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","width":1000,"height":600,"caption":"Mesenchymal stromal cells from healthy bone marrow are central to better understanding leukemia onset. This image, illustrating the cells\u2019 loopy morphology, was captured by EMBL\u2019s Zaugg group. Credit: Anna Mathioudaki\/EMBL"},{"@type":"WebSite","@id":"https:\/\/www.embl.org\/news\/#website","url":"https:\/\/www.embl.org\/news\/","name":"European Molecular Biology Laboratory News","description":"News from the European Molecular Biology Laboratory","publisher":{"@id":"https:\/\/www.embl.org\/news\/#organization"},"alternateName":"EMBL News","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.embl.org\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.embl.org\/news\/#organization","name":"European Molecular Biology Laboratory","alternateName":"EMBL","url":"https:\/\/www.embl.org\/news\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/","url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png","contentUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png","width":300,"height":144,"caption":"European Molecular Biology Laboratory"},"image":{"@id":"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/embl.org\/","https:\/\/x.com\/embl","https:\/\/www.instagram.com\/embl_org\/","https:\/\/www.linkedin.com\/company\/15813\/","https:\/\/www.youtube.com\/user\/emblmedia\/"]},{"@type":"Person","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/427f2c9b624bc32ffa67d80414712274","name":"Ivy Kupec","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/1abc86f00519d61bc0f2793ed624175c2d7ad829fb5b60e1c3b99a973ac351a6?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/1abc86f00519d61bc0f2793ed624175c2d7ad829fb5b60e1c3b99a973ac351a6?s=96&d=mm&r=g","caption":"Ivy Kupec"},"url":"https:\/\/www.embl.org\/news\/author\/ivy-kupecembl-de\/"}]}},"field_target_display":"embl","field_article_language":{"value":"english","label":"English"},"fimg_url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","featured_image_src":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/11\/PotW_MSCs.jpg","_links":{"self":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/33794","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/users\/100"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/comments?post=33794"}],"version-history":[{"count":7,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/33794\/revisions"}],"predecessor-version":[{"id":33810,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/33794\/revisions\/33810"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/media\/33796"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/media?parent=33794"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/categories?post=33794"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/tags?post=33794"},{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/embl_taxonomy?post=33794"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}