{"id":23420,"date":"2020-06-02T09:00:00","date_gmt":"2020-06-02T07:00:00","guid":{"rendered":"https:\/\/www.embl.org\/news\/?p=23420"},"modified":"2024-03-22T13:31:01","modified_gmt":"2024-03-22T12:31:01","slug":"potw2022","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/","title":{"rendered":"Organelles in space"},"content":{"rendered":"\n<p>This image, resembling a modern abstract painting, is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the <a href=\"https:\/\/www.embl.de\/research\/units\/cbb\/schwab\/index.html\">Schwab team<\/a> at EMBL Heidelberg. The rendering shows mitochondria \u2013 the power generators of a cell \u2013 in red; the endoplasmic reticulum \u2013 which plays a major role in the production, processing and transport of proteins \u2013 in yellow; and the plasma membrane \u2013 which separates the interior of the cell from the outside environment \u2013 in green. The brown spots on the mitochondria indicate sites where the endoplasmic reticulum and the mitochondria come into contact with each other. The void around which the organelles organise themselves is the location of the nucleus of the cell.<\/p>\n\n\n\n<p>Julian is using images like this to study the morphological properties of the endoplasmic reticulum, as well as contact sites that the endoplasmic reticulum forms with other organelles. To be able to study a large dataset, he relies on segmentation being done automatically using a machine-learning-based approach.<\/p>\n\n\n\n<p>For the 3D-rendering, he used raw data from a focused ion beam scanning electron microscope volume image from the HeLa cell with a resolution of 5 \u00d7 5 \u00d7 8 nanometres.<\/p>\n\n\n\n<p>HeLa is the oldest and most commonly used human cell line in scientific research. Originally, it was derived from cervical cancer cells taken on 8 February 1951 from Henrietta Lacks, a patient who died of cancer on 4 October 1951. The cells were taken without the permission of Henrietta or her family. At the time, Henrietta and her story were forgotten, but her cells went on to revolutionise medicine. We thank Henrietta for her legacy.<\/p>\n\n\n\n<p>The genome of a HeLa cell line, sequenced by scientists at EMBL Heidelberg, was made available to scientists online in 2013, following an agreement between the National Institutes of Health (NIH), in the USA, and representatives of the Lacks family.<\/p>\n\n\n\n<p>Credit: Anna Steyer &amp; Julian Hennies\/EMBL<br \/>If you have a stunning picture of your science, your lab or your site, you can submit it <a href=\"mailto:mathias.jaeger@embl.org\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This image is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the Schwab team at EMBL Heidelberg.<\/p>\n","protected":false},"author":71,"featured_media":26052,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[6,17591],"tags":[957,1718,792],"embl_taxonomy":[],"class_list":["post-23420","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-picture-of-the-week","category-science-technology","tag-hela","tag-mitochondria","tag-organelle"],"acf":{"show_featured_image":false,"featured":false,"article_intro":"","article_sources":false,"related_links":false,"in_this_article":false,"color":"#007B53","youtube_url":"","mp4_url":"","video_caption":"","translations":false,"press_contact":"None"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Organelles in space | EMBL<\/title>\n<meta name=\"description\" content=\"This image is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the Schwab team at EMBL Heidelberg.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Organelles in space | EMBL\" \/>\n<meta property=\"og:description\" content=\"This image is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the Schwab team at EMBL Heidelberg.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2020-06-02T07:00:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T12:31:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/06\/potw2022.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Mathias J\u00e4ger\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Mathias J\u00e4ger\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/\"},\"author\":{\"name\":\"Mathias J\u00e4ger\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/63a0ca26daa6707834de41dfddfc6a42\"},\"headline\":\"Organelles in space\",\"datePublished\":\"2020-06-02T07:00:00+00:00\",\"dateModified\":\"2024-03-22T12:31:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/\"},\"wordCount\":325,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/picture-of-the-week\/potw2022\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2020\/06\/potw2022.jpg\",\"keywords\":[\"hela\",\"mitochondria\",\"organelle\"],\"articleSection\":[\"Picture of the week\",\"Science &amp; 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