{"id":13823,"date":"2018-06-29T10:29:57","date_gmt":"2018-06-29T08:29:57","guid":{"rendered":"https:\/\/news.embl.de\/?p=13823"},"modified":"2024-03-22T23:21:07","modified_gmt":"2024-03-22T22:21:07","slug":"algal-nuclear-pore-complex-revealed","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/","title":{"rendered":"Algal nuclear pore complex revealed"},"content":{"rendered":"\n<p>In all eukaryotic cells genetic information is safely stored in a nucleus protected by the nuclear envelope. Openings in the nuclear envelope, called <a href=\"https:\/\/news.embl.de\/science\/cells-grow-pores-shrinking-holes\/\">nuclear pore complexes<\/a> (NPCs), have an intricate architecture. These NPCs regulate the transport of molecules to and from the cell\u2019s nucleus. Vertebrate NPCs are fairly well studied, but the question remains whether NPCs from eukaryotes belonging to different kingdoms are similar to our own.<\/p>\n\n\n\n<p>Researchers from the <a href=\"https:\/\/www.embl.de\/research\/units\/scb\/beck\/\" target=\"_blank\" rel=\"noopener noreferrer\">Beck group<\/a> at EMBL, in collaboration with Engel and Baumeister groups at the Max Planck Institute of Biochemistry, have revealed the structure of the NPC of the alga <em>Chlamydomonas reinhardtii<\/em>, in a paper published in <em>Nature Communications<\/em>. Their research reveals that there are striking differences between the human and the algal NPC. The size, diameter, and asymmetric architecture of the algal NPC are significantly different from the human NPC.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>EMBL scientists reveal NPC architecture of algae<\/p>\n","protected":false},"author":55,"featured_media":13824,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,17591],"tags":[350,43,57,539,35],"embl_taxonomy":[],"class_list":["post-13823","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-science-technology","tag-beck","tag-heidelberg","tag-postdoc","tag-research-highlight","tag-structural-biology"],"acf":{"article_intro":"<p><em>EMBL scientists reveal NPC architecture of algae <\/em><\/p>\n","related_links":[{"link_description":"Beck group","link_url":"https:\/\/www.embl.de\/research\/units\/scb\/beck\/"},{"link_description":"Cells grow pores from shrinking holes ","link_url":"https:\/\/news.embl.de\/science\/cells-grow-pores-shrinking-holes\/"},{"link_description":"Welcome: Jan Kosinski ","link_url":"https:\/\/news.embl.de\/science\/welcome-jan-kosinski\/"}],"article_sources":[{"source_description":"<p>Mosalaganti, S., Kosinski, J., Albert s., Schaffer M., <em>et al<\/em>. In situ architecture of the algal nuclear pore complex. <em>Nature Communications<\/em>, published online 18 June 2018. DOI: 10.1038\/s41467-018-04739-y<\/p>\n","source_link_url":"https:\/\/www.nature.com\/articles\/s41467-018-04739-y"}],"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Algal nuclear pore complex revealed | EMBL<\/title>\n<meta name=\"description\" content=\"EMBL scientists reveal the structure of the algal nuclear pore complex, in a paper published in Nature Communications.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Algal nuclear pore complex revealed | EMBL\" \/>\n<meta property=\"og:description\" content=\"EMBL scientists reveal the structure of the algal nuclear pore complex, in a paper published in Nature Communications.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-06-29T08:29:57+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T22:21:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/06\/1806_RH_Algal_NP-ib.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Berta Carre\u00f1o\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Berta Carre\u00f1o\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/\"},\"author\":{\"name\":\"Berta Carre\u00f1o\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/3188b4d1fc563c4c62a41ab642fda2b5\"},\"headline\":\"Algal nuclear pore complex revealed\",\"datePublished\":\"2018-06-29T08:29:57+00:00\",\"dateModified\":\"2024-03-22T22:21:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/\"},\"wordCount\":145,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/algal-nuclear-pore-complex-revealed\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/06\/1806_RH_Algal_NP-ib.jpg\",\"keywords\":[\"beck\",\"heidelberg\",\"postdoc\",\"research highlight\",\"structural biology\"],\"articleSection\":[\"Science\",\"Science &amp; 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