{"id":13770,"date":"2018-06-25T10:06:13","date_gmt":"2018-06-25T08:06:13","guid":{"rendered":"https:\/\/news.embl.de\/?p=13770"},"modified":"2024-03-22T23:21:00","modified_gmt":"2024-03-22T22:21:00","slug":"new-method-isolate-dna-rna-protein-complexes","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/","title":{"rendered":"New way to isolate DNA- and RNA-protein complexes"},"content":{"rendered":"\n<p>By interacting with nucleic acids (DNA and RNA), proteins create complexes that regulate cell behaviour. In order to understand how these complexes regulate cell function, they must be isolated from nucleic acids. Claudio Asencio, a researcher in the <a href=\"https:\/\/www.embl.de\/research\/units\/directors_research\/hentze\/index.html\" target=\"_blank\" rel=\"noopener noreferrer\">Hentze group<\/a>, has developed a new method, called Complex Capture (2C), that simplifies the extraction of complexes by using silica-based extraction columns commonly used in labs to purify nucleic acids.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein complexes<\/p>\n","protected":false},"author":55,"featured_media":13772,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,17591],"tags":[537,43,406,69,616,539,70],"embl_taxonomy":[],"class_list":["post-13770","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-science-technology","tag-dna","tag-heidelberg","tag-hentze","tag-methods","tag-protein","tag-research-highlight","tag-rna"],"acf":{"article_intro":"<p><em>EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein complexes<\/em><\/p>\n","related_links":[{"link_description":"Hentze group","link_url":"https:\/\/www.embl.de\/research\/units\/directors_research\/hentze\/index.html"}],"article_sources":[{"source_description":"<p>Asencio, C.,<em> et al<\/em>. Silica-based solid phase extraction of crosslinked nucleic acid-bound proteins. <em>Life Science Alliance<\/em>, published on 18 June, 2018. DOI: 10.26508\/lsa.201800088<\/p>\n","source_link_url":"http:\/\/www.life-science-alliance.org\/content\/1\/3\/e201800088"}],"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New way to isolate DNA- and RNA-protein complexes | EMBL<\/title>\n<meta name=\"description\" content=\"EMBL researchers develop method, called Complex Capture, that simplifies the isolation of DNA- and RNA- protein complexes\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New way to isolate DNA- and RNA-protein complexes | EMBL\" \/>\n<meta property=\"og:description\" content=\"EMBL researchers develop method, called Complex Capture, that simplifies the isolation of DNA- and RNA- protein complexes\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-06-25T08:06:13+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T22:21:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/06\/Asencio_620x425.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Berta Carre\u00f1o\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Berta Carre\u00f1o\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/\"},\"author\":{\"name\":\"Berta Carre\u00f1o\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/3188b4d1fc563c4c62a41ab642fda2b5\"},\"headline\":\"New way to isolate DNA- and RNA-protein complexes\",\"datePublished\":\"2018-06-25T08:06:13+00:00\",\"dateModified\":\"2024-03-22T22:21:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/\"},\"wordCount\":76,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-method-isolate-dna-rna-protein-complexes\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/06\/Asencio_620x425.jpg\",\"keywords\":[\"dna\",\"heidelberg\",\"hentze\",\"methods\",\"protein\",\"research highlight\",\"rna\"],\"articleSection\":[\"Science\",\"Science &amp; 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