{"id":12996,"date":"2018-04-09T17:15:26","date_gmt":"2018-04-09T15:15:26","guid":{"rendered":"https:\/\/news.embl.de\/?p=12996"},"modified":"2024-03-22T23:06:06","modified_gmt":"2024-03-22T22:06:06","slug":"new-software-3d-imaging","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/","title":{"rendered":"New software makes 3D imaging accessible"},"content":{"rendered":"\n<p>Structures inside cells, such as the nucleus and its proteins, are three dimensional. Yet scientists have often had to study such structures in 2D, because appropriately equipping microscopes was technically challenging and expensive. <a href=\"https:\/\/www.embl.de\/research\/units\/cbb\/ries\/\" target=\"_blank\" rel=\"noopener noreferrer\">Jonas Ries<\/a>, alongside his team and collaborators, have now published <a href=\"http:\/\/dx.doi.org\/10.1038\/nmeth.4661\">a paper in <em>Nature Methods<\/em><\/a>, showcasing their <a href=\"https:\/\/github.com\/jries\/fit3Dcspline\">open-source 3D imaging software<\/a>. This technology is used alongside standard microscopes, to capture high-quality images of 3D structures and reconstruct them in real-time, allowing more scientists to access robust 3D imaging techniques.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Open-source software allows standard microscopes to accurately image 3D structures<\/p>\n","protected":false},"author":59,"featured_media":13004,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,17591],"tags":[64,43,69,79],"embl_taxonomy":[],"class_list":["post-12996","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-science-technology","tag-cell-biology","tag-heidelberg","tag-methods","tag-microscopy"],"acf":{"article_intro":"<p>Open-source software allows standard microscopes to accurately image 3D structures<\/p>\n","related_links":[{"link_description":"Ries group","link_url":"https:\/\/www.embl.de\/research\/units\/cbb\/ries\/"},{"link_description":"fit3Dcspline on GitHub","link_url":"https:\/\/github.com\/jries\/fit3Dcspline"}],"article_sources":[{"source_description":"<p>Li <em>et al.,<\/em> Optimal 3D single-molecule localization in real time using experimental point spread functions, <em>Nature Methods<\/em>, published online 9 April, 2018. DOI: 10.1038\/nmeth.4661<\/p>\n","source_link_url":"dx.doi.org\/10.1038\/nmeth.4661"}],"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>New software makes 3D imaging accessible | EMBL<\/title>\n<meta name=\"description\" content=\"Open-source software, developed by scientists at EMBL, allows standard microscopes to accurately image 3D structures.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New software makes 3D imaging accessible | EMBL\" \/>\n<meta property=\"og:description\" content=\"Open-source software, developed by scientists at EMBL, allows standard microscopes to accurately image 3D structures.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2018-04-09T15:15:26+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-22T22:06:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/04\/1803_ries_feature3_ib.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Emma Steer\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Emma Steer\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\"},\"author\":{\"name\":\"Emma Steer\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/4c1a1fd8d38ed9a5cf0d0020048f6443\"},\"headline\":\"New software makes 3D imaging accessible\",\"datePublished\":\"2018-04-09T15:15:26+00:00\",\"dateModified\":\"2024-03-22T22:06:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\"},\"wordCount\":88,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/04\/1803_ries_feature3_ib.jpg\",\"keywords\":[\"cell biology\",\"heidelberg\",\"methods\",\"microscopy\"],\"articleSection\":[\"Science\",\"Science &amp; Technology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\",\"url\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\",\"name\":\"New software makes 3D imaging accessible | EMBL\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/04\/1803_ries_feature3_ib.jpg\",\"datePublished\":\"2018-04-09T15:15:26+00:00\",\"dateModified\":\"2024-03-22T22:06:06+00:00\",\"description\":\"Open-source software, developed by scientists at EMBL, allows standard microscopes to accurately image 3D structures.\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/new-software-3d-imaging\/#primaryimage\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/04\/1803_ries_feature3_ib.jpg\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2018\/04\/1803_ries_feature3_ib.jpg\",\"width\":620,\"height\":425,\"caption\":\"New software allows 3D structures to be viewed using a 2D dataset. 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