{"id":10073,"date":"2017-06-06T15:05:17","date_gmt":"2017-06-06T13:05:17","guid":{"rendered":"https:\/\/news.embl.de\/?p=10073"},"modified":"2024-03-25T09:59:30","modified_gmt":"2024-03-25T08:59:30","slug":"1705-senses-silencing-noise","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/","title":{"rendered":"Senses: Silencing noise"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">BY EDWARD DADSWELL AND MARGAUX PHARES<\/h4>\n\n\n\n<p>Somehow, the multitudes of highly specialised cells in our bodies arise from just a single cell. It\u2019s a process that might seem far removed from the changes that occur in the body during a disease. But for John Marioni and Oliver Stegle, research group leaders at EMBL-EBI, one principle ties these processes together.<\/p>\n\n\n\n<p>\u201cIn effect, we\u2019re trying to understand how cells make decisions,\u201d says Marioni. \u201cDuring development, there\u2019s a process by which a cell decides to become a particular cell type. In a similar way, you can think of disease as a cell deciding to do something it shouldn\u2019t. If we can understand how cells make these decisions, we\u2019ll learn more about normal development and potentially gain deeper insight into what\u2019s going on in disease.\u201d<\/p>\n\n\n\n<blockquote class=\"vf-blockquote\"><p>We\u2019re trying to understand how cells make decisions<\/p><\/blockquote>\n\n\n\n<div class=\"wp-block-image wp-image-10110 size-full\"><figure class=\"vf-figure  | vf-figure--align vf-figure--align-centered \"><img loading=\"lazy\" decoding=\"async\" width=\"620\" height=\"380\" class=\"vf-figure__image\" src=\"https:\/\/news.embl.de\/wp-content\/uploads\/2017\/06\/170606-Marioni.jpg\" alt=\"\" class=\"wp-image-10110\" srcset=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/06\/170606-Marioni.jpg 620w, https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/06\/170606-Marioni-300x184.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption class=\"vf-figure__caption\">John Marioni. PHOTO: EMBL\/Oana Stroe<\/figcaption><\/figure><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Silencing the cell cycle<\/h2>\n\n\n\n<p>To understand how these decisions are made, Marioni and Stegle use single-cell RNA sequencing, a technique that provides highly detailed information about the genes that are active in a cell. By studying the pattern of gene activity in many cells, they can identify different cell types. They can then start figuring out which genes are responsible for pushing a cell towards a particular fate.<\/p>\n\n\n\n<p>Unfortunately there\u2019s a problem: noise. \u201cWhen you say \u2018cell types,\u2019 there\u2019s this notion that they\u2019re rather distinct, but in practice it\u2019s more of a continuum,\u201d Stegle explains. \u201cThere\u2019s variation between cells of different types, but also between cells of the same type. Sometimes that variation is biologically interesting, but often it\u2019s a source of noise in the data \u2013 obscuring the information you really care about.\u201d<\/p>\n\n\n\n<div class=\"wp-block-image size-full wp-image-10081\"><figure class=\"vf-figure  | vf-figure--align vf-figure--align-centered \"><img loading=\"lazy\" decoding=\"async\" width=\"620\" height=\"380\" class=\"vf-figure__image\" src=\"https:\/\/news.embl.de\/wp-content\/uploads\/2017\/05\/170531-stegle1.jpg\" alt=\"\" class=\"wp-image-10081\" srcset=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-stegle1.jpg 620w, https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-stegle1-300x184.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption class=\"vf-figure__caption\">Oliver Stegle. PHOTO: Jon Mold<\/figcaption><\/figure><\/div>\n\n\n\n<p>Marioni and Stegle recently joined forces to tackle one source of noise in the data: the cell cycle. This is the repeating process in which cells copy their DNA and then divide to produce two daughter cells. As you might expect, a cell\u2019s gene activity is heavily influenced by where it is in the cell cycle. This is undoubtedly a biologically interesting process, but it\u2019s not always the one that researchers like Marioni and Stegle are interested in. That\u2019s when it becomes noise.<\/p>\n\n\n\n<p>To cut through the noise of the cell cycle, Stegle, Marioni, and their collaborators developed a new computational approach: the single-cell latent variable model (scLVM). By analysing a small number of key genes in the cell division process, they could classify each cell according to its stage in the cell cycle. They could then cancel out the effect of the cell cycle using sophisticated statistical methods in the scLVM. This makes it possible to infer \u2018corrected\u2019 gene-expression levels for a wider range of genes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">New directions<\/h2>\n\n\n\n<p>With this corrected gene expression data, the team were able to more accurately compare gene activity in different cells. The result: the detection of cells at different stages of differentiation towards an immune cell type called a T helper cell. This provides insight into basic biology and a potential avenue for disease research.<\/p>\n\n\n\n<p>Developing methods to remove the effect of the cell cycle is just one important step towards obtaining high-quality data from single-cell sequencing.<\/p>\n\n\n\n<p>\u201cOne of the limitations of our model is that you have to know the source of noise you\u2019re trying to remove,\u201d says Marioni. \u201cThe cell cycle is an important one, but there are others. The way we handle cells in the lab, for example, could increase the expression of stress-related genes. We want to take out the step where you decide in advance which noisy factors you want to remove.\u201d<\/p>\n\n\n\n<p>\u201cThat will make a huge difference,\u201d Stegle adds, \u201callowing us to cut out noise and let the meaningful biological signals come through.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Two EMBL researchers are exploring new ways to filter out noise and get to the data they need<\/p>\n","protected":false},"author":16,"featured_media":10074,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2,17591],"tags":[64,36,183,408,513,470],"embl_taxonomy":[],"class_list":["post-10073","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","category-science-technology","tag-cell-biology","tag-embl-ebi","tag-gene-expression","tag-marioni","tag-sense","tag-stegle"],"acf":{"article_intro":"<p>Two EMBL researchers are exploring new ways to filter out noise and get to the data they need<\/p>\n","related_links":[{"link_description":"Senses: What you see is how you feel","link_url":"https:\/\/news.embl.de\/science\/1705-senses-see-feel\/"}],"article_sources":false,"vf_locked":false,"featured":false,"color":"#007B53"},"embl_taxonomy_terms":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Senses: Silencing noise | EMBL<\/title>\n<meta name=\"description\" content=\"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Senses: Silencing noise | EMBL\" \/>\n<meta property=\"og:description\" content=\"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:published_time\" content=\"2017-06-06T13:05:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-03-25T08:59:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"620\" \/>\n\t<meta property=\"og:image:height\" content=\"425\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Guest author(s)\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@embl\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Guest author(s)\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"NewsArticle\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\"},\"author\":{\"name\":\"Guest author(s)\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/b4d9366b2ebe691c4015c64c3619205b\"},\"headline\":\"Senses: Silencing noise\",\"datePublished\":\"2017-06-06T13:05:17+00:00\",\"dateModified\":\"2024-03-25T08:59:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\"},\"wordCount\":639,\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg\",\"keywords\":[\"cell biology\",\"embl-ebi\",\"gene expression\",\"marioni\",\"sense\",\"stegle\"],\"articleSection\":[\"Science\",\"Science &amp; Technology\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\",\"url\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\",\"name\":\"Senses: Silencing noise | EMBL\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg\",\"datePublished\":\"2017-06-06T13:05:17+00:00\",\"dateModified\":\"2024-03-25T08:59:30+00:00\",\"description\":\"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need\",\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg\",\"width\":620,\"height\":425,\"caption\":\"IMAGE: EMBL\/Spencer Phillips\"},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.embl.org\/news\/#website\",\"url\":\"https:\/\/www.embl.org\/news\/\",\"name\":\"European Molecular Biology Laboratory News\",\"description\":\"News from the European Molecular Biology Laboratory\",\"publisher\":{\"@id\":\"https:\/\/www.embl.org\/news\/#organization\"},\"alternateName\":\"EMBL News\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.embl.org\/news\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.embl.org\/news\/#organization\",\"name\":\"European Molecular Biology Laboratory\",\"alternateName\":\"EMBL\",\"url\":\"https:\/\/www.embl.org\/news\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png\",\"width\":300,\"height\":144,\"caption\":\"European Molecular Biology Laboratory\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/embl.org\/\",\"https:\/\/x.com\/embl\",\"https:\/\/www.instagram.com\/embl_org\/\",\"https:\/\/www.linkedin.com\/company\/15813\/\",\"https:\/\/www.youtube.com\/user\/emblmedia\/\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/b4d9366b2ebe691c4015c64c3619205b\",\"name\":\"Guest author(s)\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/300b9a1d66050ae03eaeb99869c6ebb30f5184b9468e92a2b3e7d28bc9cf742d?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/300b9a1d66050ae03eaeb99869c6ebb30f5184b9468e92a2b3e7d28bc9cf742d?s=96&d=mm&r=g\",\"caption\":\"Guest author(s)\"},\"description\":\"Guest author(s)\",\"url\":\"https:\/\/www.embl.org\/news\/author\/guest-author\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Senses: Silencing noise | EMBL","description":"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/","og_locale":"en_US","og_type":"article","og_title":"Senses: Silencing noise | EMBL","og_description":"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need","og_url":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/","og_site_name":"EMBL","article_publisher":"https:\/\/www.facebook.com\/embl.org\/","article_published_time":"2017-06-06T13:05:17+00:00","article_modified_time":"2024-03-25T08:59:30+00:00","og_image":[{"width":620,"height":425,"url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","type":"image\/jpeg"}],"author":"Guest author(s)","twitter_card":"summary_large_image","twitter_creator":"@embl","twitter_site":"@embl","twitter_misc":{"Written by":"Guest author(s)","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"NewsArticle","@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#article","isPartOf":{"@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/"},"author":{"name":"Guest author(s)","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/b4d9366b2ebe691c4015c64c3619205b"},"headline":"Senses: Silencing noise","datePublished":"2017-06-06T13:05:17+00:00","dateModified":"2024-03-25T08:59:30+00:00","mainEntityOfPage":{"@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/"},"wordCount":639,"publisher":{"@id":"https:\/\/www.embl.org\/news\/#organization"},"image":{"@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage"},"thumbnailUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","keywords":["cell biology","embl-ebi","gene expression","marioni","sense","stegle"],"articleSection":["Science","Science &amp; Technology"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/","url":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/","name":"Senses: Silencing noise | EMBL","isPartOf":{"@id":"https:\/\/www.embl.org\/news\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage"},"image":{"@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage"},"thumbnailUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","datePublished":"2017-06-06T13:05:17+00:00","dateModified":"2024-03-25T08:59:30+00:00","description":"Two EMBL researchers, John Marioni and Oliver Stegle are exploring new ways to filter out noise and get to the data they need","inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/science\/1705-senses-silencing-noise\/#primaryimage","url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","contentUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","width":620,"height":425,"caption":"IMAGE: EMBL\/Spencer Phillips"},{"@type":"WebSite","@id":"https:\/\/www.embl.org\/news\/#website","url":"https:\/\/www.embl.org\/news\/","name":"European Molecular Biology Laboratory News","description":"News from the European Molecular Biology Laboratory","publisher":{"@id":"https:\/\/www.embl.org\/news\/#organization"},"alternateName":"EMBL News","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.embl.org\/news\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.embl.org\/news\/#organization","name":"European Molecular Biology Laboratory","alternateName":"EMBL","url":"https:\/\/www.embl.org\/news\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/","url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png","contentUrl":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/09\/EMBL_logo_colour-1-300x144-1.png","width":300,"height":144,"caption":"European Molecular Biology Laboratory"},"image":{"@id":"https:\/\/www.embl.org\/news\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/embl.org\/","https:\/\/x.com\/embl","https:\/\/www.instagram.com\/embl_org\/","https:\/\/www.linkedin.com\/company\/15813\/","https:\/\/www.youtube.com\/user\/emblmedia\/"]},{"@type":"Person","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/b4d9366b2ebe691c4015c64c3619205b","name":"Guest author(s)","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.embl.org\/news\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/300b9a1d66050ae03eaeb99869c6ebb30f5184b9468e92a2b3e7d28bc9cf742d?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/300b9a1d66050ae03eaeb99869c6ebb30f5184b9468e92a2b3e7d28bc9cf742d?s=96&d=mm&r=g","caption":"Guest author(s)"},"description":"Guest author(s)","url":"https:\/\/www.embl.org\/news\/author\/guest-author\/"}]}},"field_target_display":"embl","field_article_language":{"value":"english","label":"English"},"fimg_url":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","featured_image_src":"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170531-Marioni-Stegle_ib.jpg","_links":{"self":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/10073","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/comments?post=10073"}],"version-history":[{"count":8,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/10073\/revisions"}],"predecessor-version":[{"id":20817,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/posts\/10073\/revisions\/20817"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/media\/10074"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/media?parent=10073"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/categories?post=10073"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/tags?post=10073"},{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/news\/wp-json\/wp\/v2\/embl_taxonomy?post=10073"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}