{"id":10026,"date":"2017-05-29T11:10:22","date_gmt":"2017-05-29T09:10:22","guid":{"rendered":"https:\/\/news.embl.de\/?p=10026"},"modified":"2024-03-22T16:39:15","modified_gmt":"2024-03-22T15:39:15","slug":"1705-james-sharpe-head-of-embl-barcelona","status":"publish","type":"post","link":"https:\/\/www.embl.org\/news\/lab-matters\/1705-james-sharpe-head-of-embl-barcelona\/","title":{"rendered":"James Sharpe appointed Head of EMBL Barcelona"},"content":{"rendered":"\n<p>James Sharpe, who invented a 3D imaging technique for looking at tissues and organs, will be the first Head of <a href=\"http:\/\/www.embl-barcelona.es\/aboutus\/general_information\/about-embl-barcelona\/index.html\">EMBL Barcelona<\/a>. The new EMBL site will focus on tissue biology and disease modelling, and make state-of-the-art imaging technologies like Sharpe\u2019s available to scientists worldwide. Sharpe, who currently leads the <a href=\"http:\/\/www.crg.eu\/en\/programmes-groups\/multicellular-systems-biology\">Systems Biology Programme at the Centre for Genomic Regulation (CRG)<\/a> in Barcelona, is expected to start his lab at EMBL this Autumn.<\/p>\n\n\n\n<div class=\"wp-block-image size-full wp-image-10033\"><figure class=\"vf-figure  | vf-figure--align vf-figure--align-centered \"><img loading=\"lazy\" decoding=\"async\" width=\"620\" height=\"425\" class=\"vf-figure__image\" src=\"https:\/\/news.embl.de\/wp-content\/uploads\/2017\/05\/170529-Sharpe_ib.jpg\" alt=\"James Sharpe, new Head of EMBL Barcelona. IMAGE: CRG\" class=\"wp-image-10033\" srcset=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170529-Sharpe_ib.jpg 620w, https:\/\/www.embl.org\/news\/wp-content\/uploads\/2017\/05\/170529-Sharpe_ib-300x206.jpg 300w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption class=\"vf-figure__caption\">James Sharpe, new Head of EMBL Barcelona. IMAGE: CRG<\/figcaption><\/figure><\/div>\n\n\n\n<p>Sharpe was originally interested in computer programing, but during his studies at Oxford University, he became captivated by the parallels between electronic circuits and how gene networks control the development of tissues and organs. To pursue this interest, he did a PhD in mouse developmental genetics, and then in 1998 he brought these two interests together: he started creating computer models of how limbs form \u2013 a paradigmatic example of organogenesis. But getting data to base those models on was difficult. Existing technologies were not suited to imaging whole body parts as they develop. So in 2001 Sharpe invented a new 3D imaging technique: Optical Projection Tomography. With this technique scientists could, for the first time, get detailed images of samples between 1mm and 1cm in size. In 2006, Sharpe moved to the CRG to continue exploring limb development by combining experiments, imaging and computer modelling. Sharpe\u2019s lab at EMBL Barcelona will continue to draw on these different approaches to explore how genes, molecules and cells come together to form a limb.<\/p>\n\n\n\n<p>In his role as Head of EMBL Barcelona, Sharpe will next be looking to recruit a Head of Core Facility to lead the site\u2019s state-of-the-art offerings in imaging technologies. Soon after, he will be recruiting the first new group leaders, who will start early 2018. The new unit aims to cover a broad scope of multicellular systems, including organoids, tissue engineering, regeneration and more.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Inventor of OPT will be the first Head of EMBL\u2019s new Barcelona site<\/p>\n","protected":false},"author":8,"featured_media":10150,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[17597,3],"tags":[497,501,500,431],"embl_taxonomy":[9762],"class_list":["post-10026","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-embl-announcements","category-lab-matters","tag-barcelona","tag-disease-modelling","tag-sharpe","tag-tissue-biology","embl_taxonomy-embl-barcelona"],"acf":{"article_intro":"<p>James Sharpe, who invented a 3D imaging technique for looking at tissues and organs, will be the first Head of EMBL\u2019s new Barcelona site<\/p>\n","related_links":[{"link_description":"Welcome: James Sharpe","link_url":"https:\/\/news.embl.de\/science\/welcome-james-sharpe\/"},{"link_description":"Sharpe interviewed in La Vanguardia (Spanish)","link_url":"http:\/\/www.lavanguardia.com\/ciencia\/20170529\/423030940350\/james-sharpe-primer-director-embl-barcelona.html"},{"link_description":"Sharpe's lab in Barcelona","link_url":"http:\/\/www.crg.eu\/en\/programmes-groups\/multicellular-systems-biology"},{"link_description":"More about EMBL Barcelona","link_url":"http:\/\/www.embl-barcelona.es\/aboutus\/general_information\/about-embl-barcelona\/index.html"}],"article_sources":false,"vf_locked":false,"featured":false,"color":"#007B53","link_color":"#fff","show_featured_image":false,"in_this_article":false,"youtube_url":"","mp4_url":"","video_caption":"","press_contact":"None","translations":false},"embl_taxonomy_terms":[{"uuid":"a:3:{i:0;s:36:\"b14d3f13-5670-44fb-8970-e54dfd9c921a\";i:1;s:36:\"89e00fee-87f4-482e-a801-4c3548bb6a58\";i:2;s:36:\"762176bb-d12e-4c94-8964-6dbb76e15c42\";}","parents":[],"name":["EMBL Barcelona"],"slug":"embl-barcelona","description":"Where &gt; All EMBL sites &gt; EMBL Barcelona"}],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>James Sharpe appointed Head of EMBL Barcelona | EMBL<\/title>\n<meta name=\"description\" content=\"James Sharpe, inventor of 3D imaging technique for looking at tissues and organs 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