{"id":75401,"date":"2025-07-22T17:16:37","date_gmt":"2025-07-22T15:16:37","guid":{"rendered":"https:\/\/www.embl.org\/news\/?post_type=awards&#038;p=75401"},"modified":"2025-07-22T17:29:09","modified_gmt":"2025-07-22T15:29:09","slug":"french-german-partnership-in-cancer-research-celebrated","status":"publish","type":"awards","link":"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated","title":{"rendered":"French-German partnership in cancer research celebrated"},"content":{"rendered":"\n<p>Eva Kowalinski, EMBL Group Leader, in collaboration with Stefanie Kaiser from <a href=\"https:\/\/www.goethe-university-frankfurt.de\/en\">Goethe University<\/a>, recently received recognition from the <a href=\"https:\/\/de.ambafrance.org\/\">French Embassy in Germany<\/a> and the <a href=\"https:\/\/www.dfh-ufa.org\/en\/?noredirect=en_US\">Franco-German University<\/a>. Their research project \u2018<a href=\"https:\/\/doi.org\/10.1038\/s41594-024-01341-3\">Therapeutic Potential of tRNA Methyltransferases Targeting 3-methyl-cytosine<\/a>\u2019 seeks to identify novel active compounds against cancer by modifying RNA structures.<\/p>\n\n\n\n<p>Kowalinski has a long history with EMBL and with research on the interplay of protein complexes with RNA molecules. She first arrived in 2006 for her PhD, focusing on gaining a deeper understanding of how viral RNA activates the innate immune pattern-recognition receptor RIG-I. After a period at the <a href=\"https:\/\/www.biochem.mpg.de\/en\">Max Planck Institute of Biochemistry, Munich<\/a>, she returned to EMBL&#8217;s Grenoble site in 2017 as a Group Leader, continuing her exploration of the fundamental relationships between proteins and RNA.<\/p>\n\n\n\n<blockquote class=\"vf-blockquote | vf-u-margin__bottom--600 vf-u-margin__top--600\">\n  <div>\n    <div>\n      &#8220;I can speak for both of us when I say that the Prix Forcheurs Jean-Marie Lehn is a great honour for us,\u201d Kowalinski said. \u201cScience needs cross-cultural exchange, and I am glad that we live in a Europe where such exchange is encouraged and made so easily possible. Our two teams complement each other perfectly, and we are united by the goal of discovering novel active agents against very common types of cancer.&#8221;    <\/div>\n    \n      <\/div>\n<\/blockquote>\n\n\n\n<p>Stefanie and Eva recently deciphered how METTL6, an enzyme that plays an important role in many biological processes, including tumour cell growth, binds to RNA. This led to a joint publication on the enzyme\u2019s structure in complex with its cofactors. Their current goal is to harness the potential of METTL6 and a family of related proteins as drug targets, given that members of this enzyme family play significant roles in cancers, as well as metabolic and neurological diseases.<\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-full is-style-default\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"512\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/25-06_Prix-forcheurs_Copyright-Ambassade-de-France-en-Allemagne-1024x512-1.jpg\" alt=\"From left to right: Fran\u00e7ois Delattre (Ambassade de France), Christina Gommlich (BASF), laureates Stefanie Kaiser (Goethe-Universit\u00e4t Frankfurt) and Eva Kowalinski (EMBL Grenoble) -holding their respective awards, Jean-Marie Lehn (1987 chemistry nobel prize winner and eponymous patron of the prize), Antoine Triller (Acad\u00e9mie des Sciences), Christian Lerche (Sanofi), and Eva Martha Eckkrammer (UFA) standing on stage during rhe Forcheurs Prize ceremony in Berlin.\n\" class=\"wp-image-75403\" srcset=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/25-06_Prix-forcheurs_Copyright-Ambassade-de-France-en-Allemagne-1024x512-1.jpg 1024w, https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/25-06_Prix-forcheurs_Copyright-Ambassade-de-France-en-Allemagne-1024x512-1-300x150.jpg 300w, https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/25-06_Prix-forcheurs_Copyright-Ambassade-de-France-en-Allemagne-1024x512-1-768x384.jpg 768w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"vf-figure__caption\">\u00a0From left to right: Fran\u00e7ois Delattre (Ambassade de France), Christina Gommlich (BASF), laureates Stefanie Kaiser (Goethe-Universit\u00e4t Frankfurt) and Eva Kowalinski (EMBL Grenoble), Jean-Marie Lehn (1987 Chemistry Nobel Prize winner and the eponymous patron of the prize), Antoine Triller (Acad\u00e9mie des Sciences), Christian Lerche (Sanofi), and Eva Martha Eckkrammer (UFA) at the Forcheurs Prize ceremony in Berlin. Copyright: Ambassade de France en Allemagne\u00a0<\/figcaption><\/figure>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>A collaborative research project, co-authored by Eva Kowalinski, has been awarded the Forcheurs Jean-Marie Lehn Prize 2025.<\/p>\n","protected":false},"author":179,"featured_media":75485,"parent":0,"menu_order":0,"template":"","tags":[38,37,541,70,35],"award-type":[17599],"award-unit":[17651],"award-site":[17603],"class_list":["post-75401","awards","type-awards","status-publish","has-post-thumbnail","hentry","tag-cancer","tag-grenoble","tag-kowalinski","tag-rna","tag-structural-biology","award-type-award","award-unit-structural-biology-gr","award-site-grenoble"],"acf":{"vf-news-ah-unit":[17651],"vf-news-ah-type":[17599],"vf-news-ah-site":[17603]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.2 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>French-German partnership in cancer research celebrated | EMBL<\/title>\n<meta name=\"description\" content=\"An EMBL Grenoble Group Leader has been awarded the Frocheurs Jean-Mari Lehn Prize 2025\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"French-German partnership in cancer research celebrated | EMBL\" \/>\n<meta property=\"og:description\" content=\"An EMBL Grenoble Group Leader has been awarded the Frocheurs Jean-Mari Lehn Prize 2025\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/\" \/>\n<meta property=\"og:site_name\" content=\"EMBL\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/embl.org\/\" \/>\n<meta property=\"article:modified_time\" content=\"2025-07-22T15:29:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/Untitled-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"600\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@embl\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/\",\"url\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/\",\"name\":\"French-German partnership in cancer research celebrated | EMBL\",\"isPartOf\":{\"@id\":\"https:\/\/www.embl.org\/news\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/Untitled-1.jpg\",\"datePublished\":\"2025-07-22T15:16:37+00:00\",\"dateModified\":\"2025-07-22T15:29:09+00:00\",\"description\":\"An EMBL Grenoble Group Leader has been awarded the Frocheurs Jean-Mari Lehn Prize 2025\",\"breadcrumb\":{\"@id\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.embl.org\/news\/awards-honours\/french-german-partnership-in-cancer-research-celebrated\/#primaryimage\",\"url\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/Untitled-1.jpg\",\"contentUrl\":\"https:\/\/www.embl.org\/news\/wp-content\/uploads\/2025\/07\/Untitled-1.jpg\",\"width\":1000,\"height\":600,\"caption\":\"Portrait of Eva Kowalinski illustrating her 2025 Forcheurs Jean-Marie Lehn award. 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