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Research highlights

The E. coli peptide transporter DtpA in complex with nanobody N00 and the prodrug valganciclovir (highlighted) Credit: Yonca Ural Blimke/EMBL

Structure of prodrug-transporter complex revealed

Scientists develop structural model that could help in the development of drugs with increased absorption…

By Guest author(s)

Science

A network of interacting RNAs and proteins is active in each of our cells.

New ways to look at protein-RNA networks

Researchers develop new method to analyse the entire protein-RNA network of the…

By Guest author(s)

Science

Infographic on how X-RAY crystallography works. IMAGE: Tobias Wüstefeld

Time-resolved X-ray crystallography simplified

Speeding up time-resolved X-ray crystallography with EMBL beamline…

By Guest author(s)

Science

How cellular signalling controls chromatin modification. IMAGE: Aleksandra Krolik/EMBL

Transcription factors controlled by DNA sequence

EMBL scientists gain mechanistic insights into how cellular signalling controls gene…

By Patrick Mueller

Science

The retromer complex

Solving the structure of retromer

Retromer’s 3D structure improves understanding of cellular sorting and…

By Guest author(s)

Science

IMAGE: Manon Boschard

X-rays reveal surprising shape of scaffolding protein

X-ray experiments show that scaffolding protein PDZK1 has a L-shaped…

By Iris Kruijen

Science

During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

Cohesin: a glue for DNA

EMBL scientists discover how a component of the cohesin ring binds…

By Patrick Mueller

Science

The proteins behind hungry cells

EMBL researchers visualise the proteins needed to capture molecules and bring them into a…

By Emma Steer

Science

Architectural comparison of the Chlamydomonas reinhardtii NPC (left) and the human NPC (right). IMAGE: Shyamal Mosalaganti/EMBL

Algal nuclear pore complex revealed

EMBL scientists reveal NPC architecture of…

By Berta Carreño

Science

New method using silica-based columns simplifies the extraction of DNA – and RNA-protein complexes. IMAGE: Adobe stock

New way to isolate DNA- and RNA-protein complexes

EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein…

By Berta Carreño

Science

Intermediate detection in capsid formation of the lumazine synthase enzyme. CREDIT: Aleksandra Krolik / EMBL

Reconstructing 3D shapes from unmeasurable data

Scientists at EMBL Hamburg determine shapes of intermediate states in dynamic biological…

By Iris Kruijen

Science

Dividing cell colored in a heat gradient, highlighting the variation in proteins’ thermal stability within and between different cell cycle stages. IMAGE: Aleksandra Krolik / EMBL

Protein stability and solubility during cell cycle

EMBL scientists uncover large solubility and thermal stability changes of proteins during the cell…

By Iris Kruijen

Science

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