Research highlights
Enabling functional genomics studies in individual cells
Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
New insights into gene regulation
EMBL researchers investigate the role of a histone protein in regulating gene expression…
Finding your way around Platynereis dumerilii
EMBL researchers combine multiple datasets to develop expandable atlas of an entire animal…
How transcription factors work together
EMBL researchers have developed a method to observe interactions between transcription factors…
A classification tool for transcription factors
The software diffTF quantifies activity of transcription factors and predicts their mode of action…
Understanding a key player in melanoma
A new paper describes a unique mechanism of partner selectivity in transcription factors.…
Photo-micropatterning advances structural cell biology
A new technique in cryo-EM…
New perspectives on nuclear pores
EMBL researchers have published two new studies involving the nuclear pore complex…
Transcriptional hubs confer phenotypic robustness
Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions…
A tRNA modifier at work
Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.…
