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Research highlights

An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…

By Marius Bruer

Science

New insights into gene regulation

EMBL researchers investigate the role of a histone protein in regulating gene expression…

By Chloe Cross

Science

PlatyBrowser

Finding your way around Platynereis dumerilii

EMBL researchers combine multiple datasets to develop expandable atlas of an entire animal…

By Marius Bruer

Science

Forkhead-Ets cooperation

How transcription factors work together

EMBL researchers have developed a method to observe interactions between transcription factors…

By Fabian Oswald

Science

TF bound to DNA

A classification tool for transcription factors

The software diffTF quantifies activity of transcription factors and predicts their mode of action…

By Fabian Oswald

Science

mitf stammer

Understanding a key player in melanoma

A new paper describes a unique mechanism of partner selectivity in transcription factors.…

By Fabian Oswald

Science

Cryo-ET and micropatterning

Photo-micropatterning advances structural cell biology

A new technique in cryo-EM…

By Cella Carr

Science

New perspectives on nuclear pores

EMBL researchers have published two new studies involving the nuclear pore complex…

By Fabian Oswald

Science

Stripes of colour display gene expression patterns

Transcriptional hubs confer phenotypic robustness

Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions…

By Josh Tapley

Science

Structure of the Elongator complex

A tRNA modifier at work

Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.…

By Cella Carr

Science

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