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Jürg Müller

These microscopy images show the region of the embryo larva that will develop into the adult fruit fly’s wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) - a situation which is corrected when PR-DUB’s activity is restored (right). Image credits: J.Mueller/EMBL.

Tags on, tags off

During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing…

By Guest author(s)

Science

Sugarcoating fruit fly development

Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical…

By Guest author(s)

Science

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