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Developmental biology

Synchronised waves control embryonic patterning

Synchronised waves control embryonic patterning

EMBL scientists show that the rhythm between Wnt and Notch waves enables patterning in embryos.

By Iris Kruijen

Science

Sync to grow

In a nutshell: The size of pre-vertebrae in a mammalian embryo is controlled by a wave-like gene expression pattern along its back The size of each pre-vertebra is proportional to the speed of the wave: the faster the wave, the bigger the vertebra Embryonic cells coordinate gene activities with…

By Guest author(s)

Science

Diagram of chromatin enhancers

Tracking genes’ remote controls

As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…

By Guest author(s)

Science

The informant: a jumping gene

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to…

By Guest author(s)

Science

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