Edit

EMBL Taxonomy:

EMBL Heidelberg

Year
4 December 2024

From snapshots to motion: watching biology in action

Science & Technology With a novel approach, EMBL scientists discovered important interactions between molecular machines, potentially offering new opportunities for drug development.

2024

science-technology

15 November 2024 Woman in red jacket outdoors with fall foliage behind her

The value of a scientific meet-up

Connections Yuvarani Masarapu, a junior bioinformatician and doctoral student at SciLifeLab in Stockholm, spent a week with EMBL collaborators, finding solutions to research challenges and expanding her scientific perspective.

2024

connections

13 November 2024 Illustration showing a human gut floating over a scale resting on a microchip labelled ‘AI’. The two sides of the scale show a varying number of bacteria, shown against a backdrop of 0s and 1s.

Microbial load can influence disease associations

Science & Technology Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.

2024

science-technology

31 October 2024 Woman with crossed arms stands in front of tree

Welcome: Isabella Graf

People & Perspectives Isabella Graf is EMBL’s newest group leader and the first theoretical biophysicist to join the Developmental Biology Unit.

2024

people-perspectives

28 October 2024 A mixed group of people standing on a set of stairs outside a building.

Empowering research infrastructure scientists

Connections The ARISE summer school brought together fellows from across EMBL sites who are working on technology projects as part of EMBL’s Career Accelerator for Research Infrastructure Scientists (ARISE) programme.

2024

connections

10 October 2024 A multi-coloured donut representing the structure of an NPC.

“Structurally” sound

Science & Technology The function of biological molecules is intimately linked to their structure. In the 50 years since EMBL was established, its researchers and engineers have constantly provided leadership in structural biology research and services, resulting in many scientific breakthroughs and novel insights.

2024

science-technology

8 October 2024

Machine learning discoveries honoured with 2024 Nobel Prize for Physics

Science & Technology The prize was awarded to John J. Hopfield, Princeton University, USA, and Geoffrey Hinton, University of Toronto, Canada, for their seminal contributions to the foundational methods that enabled the development of machine learning.

2024

science-technology

8 October 2024 Illustration showing a mitochondrion covered with many ribosomes on the left, and a zoom in to the molecular structure of a ribosome facing a membrane with its smaller subunit on the right.

What we can learn from hungry yeast cells

Science & Technology Scientists at EMBL Heidelberg and University of Virginia revealed a new cellular response to starvation: ribosomes attach to the mitochondrial outer membrane in a very unusual way, via their small subunit. The finding made in yeast might provide insights into how cancer cells survive the harsh…

2024

science-technology

10 September 2024 A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

Follow the cellular road

Science & Technology An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.

2024

science-technology

21 August 2024 Three images of the cell at different stages of mitosis. In the left: round navy shape and irregular thick magenta line within it. In the middle: the same round shape with two irregular magenta shapes. On the right: Two round navy shapes connected with each other. Each of them holds shiny magenta-yellow clusters.

The forces behind chromosome repulsion and attraction during cell division

Science & Technology EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.

2024

science-technology

14 August 2024

Merging passion, collaboration, and serendipity

People & Perspectives EMBL alumnus Thibaut Brunet, recipient of the 2024 John Kendrew Young Scientist Award, shares his scientific journey – from a childhood passion for nature to the discovery of a new species of choanoflagellate.

2024

people-perspectives

31 July 2024 Silhouette of gastrointestinal track alongside an illustrator's representation of the carcinogens and antibiotics that seem to be affected by the gut microbiome

Gut microbes implicated in bladder cancer

Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.

2024

science-technology

18 June 2024 A progression of three images against a blue/purple background. Each image shows a simulated mouse embryo inner cell mass with two types of cells marked in pink and green respectively. From the first to the third image, the pink cells slowly move from the outer edge to the inside of the mass.

Minecraft-ing our way into studying cell sorting

Science & Technology A theoretical model involving tiny Minecraft-like cubes can help us understand dynamic biological processes, such as cell sorting in embryos.

2024

science-technology

22 May 2024 A sphere with two separated halves; the left half is blue and depicts chromosomes separating along spindles inside multiple nuclei, while the right half is orange, depicting a single set of chromosomes and a spindle with no nuclear envelope visible.

Exploring diversity in cell division

Science & Technology New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.

2024

science-technology

14 May 2024

Toby Gibson: what I’ve learned

People & Perspectives Toby Gibson reflects on 38 years at EMBL, the scientific tools he built along the way, and the state of science today.

2024

people-perspectives

23 April 2024 This image showcases a processor with neon lights and abstract shapes that represent the flow and integration of spatial omics information. The background shows the analyzed and annotated breast cancer sample.

A universal framework for spatial biology

Science & Technology SpatialData is a tool developed by EMBL scientists in cooperation with multiple research institutions to unify and integrate data from different omics technologies in a spatial environment, providing holistic insights into health and disease. Researchers can now freely access and use SpatialData…

2024

science-technology

22 April 2024 A woman is looking through a book and checking a microscopy image on the screen of a laptop in front of her. On her left, there is the Curiosity microscope, which consists of grey, blue and yellow blocks connected with a red stripe.

Sparking curiosity: the Curiosity microscope

Lab Matters BIOcean5D is an EMBL-coordinated project co-funded by the European Union that unites 31 institutes to address pressing global challenges on marine biodiversity.

2024

lab-matters

20 March 2024 4 people are standing in front of a man, Vladimir Benes, who speaks to them

Connecting shores and exploring new avenues for collaboration with Malta

Connections During a visit from high-level representatives of EMBL’s member state Malta, the honourable delegation allowed a peek behind the scenes of their scientific and institutional collaborations, and shared their memories and future aspirations for the partnership.

2024

connectionsevents

11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

1 February 2024

We are EMBL: Renato Alves on Bio-IT and stargazing

Lab MattersPeople & Perspectives Renato Alves talks about his time at EMBL, the Bio-IT project, his wishes for EMBL in its anniversary year, and how a passion for night hikes and stargazing led to the creation of EMBL’s astronomy club.

2024

lab-matterspeople-perspectives

25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Science & Technology Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

2024

sciencescience-technology

23 November 2023 Photographs of two scientists on a decorative background

ERC Consolidator Grants awarded to two EMBL researchers

EMBL AnnouncementsLab Matters Alba Diz-Muñoz and Arnaud Krebs from EMBL Heidelberg have received grants to work on projects that aim, respectively, to understand the cellular mechanics that control cell division and investigate the regulatory networks that govern transcription factor function.

2023

embl-announcementslab-matters

22 November 2023 Oliver Stegle passionately drawing work-related content with a green pen on a whiteboard. On the whiteboard, there are coordinates and equations, such as “n=2”.

How AI shapes the life sciences: an interview with Oliver Stegle

Lab MattersPeople & Perspectives EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.

2023

lab-matterspeople-perspectives

31 October 2023

EMBL’s southern hemisphere connection

ConnectionsLab Matters Ian Smith, Chair of EMBL Australia´s Council, chats about the synergies between the organisations, opportunities for collaboration, and ideas for exciting new programmes arising out of a recent visit to EMBL Heidelberg.

2023

connectionslab-matters

27 October 2023 The image shows a uerine environment made of a jelly-like and transparent material, with a cylindrical 3D structure.

Spotlight: Creating an artificial uterus

Science & Technology EMBL researchers have created an engineered uterus that allows a closer look at a mouse embryo’s development and its interactions with the uterine environment.

2023

picture-of-the-weeksciencescience-technology

26 October 2023 Photographs of three scientists on a decorative blue background

EMBL scientists receive prestigious ERC Synergy Grants

EMBL Announcements Jan Kosinski, Julia Mahamid, and Georg Zeller have received grants to enable ambitious projects aimed at mapping the cellular protein synthesis machinery in context and understanding complex host-microbiome interactions, respectively.

2023

embl-announcementsscience

6 October 2023

We are EMBL: Zuzana Koskova on her experience as a PhD student at EMBL Heidelberg

Lab MattersPeople & Perspectives Zuzana Koskova is a PhD student from Slovakia who, at the age of 19, left her country to pursue her career in biological sciences in Germany. In this interview, she talks about her interests, career aspirations, and recent participation at the Info Day held in Bratislava, where she had the…

2023

lab-matterspeople-perspectives

28 September 2023 Visual of AlphaFold Protein prediction, embedded into a visual of scientific data

EMBL receives German AI prize

EMBL Announcements EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.

2023

embl-announcementsscience

5 September 2023 Faces of Jordi van Gestel and Maria Zimmermann-Kogadeeva.

ERC starting grants for two EMBL Heidelberg researchers

EMBL AnnouncementsLab Matters Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR funding for research projects on microbial predators and the gut microbiome respectively

2023

embl-announcementslab-matters

21 July 2023 Three-dimensional cartoon of the hexasome with a chromatin remodeler on DNA.

A glimpse into the hexasome: 40 years on

Science & Technology Research from the Eustermann group at EMBL Heidelberg reveals how the packaging of DNA into hexasomes impacts the function of enzymes involved in gene regulation.

2023

sciencescience-technology

4 July 2023 Photos of the three scientists elected as EMBO members on green background.

EMBL scientists elected to EMBO Membership

Lab MattersPeople & Perspectives Three EMBL group leaders and six EMBL alumni were recognised for their contributions to the life sciences.

2023

lab-matterspeople-perspectives

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

2023

sciencescience-technology

11 May 2023 An colourful image taken from the World of Molecular Biology exhibition.

The World of Molecular Biology is open 

EMBL AnnouncementsLab Matters EMBL´s new permanent exhibition ‘The World of Molecular Biology’ in Heidelberg is now open for registration. The exhibition takes the visitor on a journey of scales, from genomes to ecosystems, and introduces key imaging technologies.

2023

embl-announcementslab-matters

20 February 2023 The Estonian flag

EMBL welcomes Estonia as full member

EMBL AnnouncementsLab Matters The Baltic nation of Estonia has become a full member of EMBL, joining the organisation as its 28th member state.

2023

embl-announcementslab-matters

2 February 2023 Science illustration showing from left to right the progression from cryo-EM software to an annotated image of sub-cellular organelles, using a deep learning software.

AI helps scientists decipher cellular structures

New artificial intelligence tool adds speed and detailed cellular information to analysis of cryo-electron tomography to aid researchers’ understanding of inner cell workings.

2023

science

25 January 2023 A group photo from the BiOcean5D launch meeting

BIOcean5D targets marine biodiversity

ConnectionsLab Matters EMBL hosts inaugural meeting for major interdisciplinary project designed to boost understanding of ocean life

2023

connectionslab-matters

4 January 2023 Confocal microscopy of dynamic concentration of nucleoporins (top) and 3D model of postmitotic assembly pathway of the nuclear pore complex over a time scope of 60 minutes during cell division.

Step-by-step guide to nuclear pore complex assembly

Science & Technology EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.

2023

sciencescience-technology

17 November 2022 A graphic showing the logos of EMBL and the University of Malta

EMBL builds on links with Malta

Connections EMBL deepens scientific collaboration, opening the door for greater engagement and opportunities for Malta’s life science community

2022

connectionsevents

12 October 2022 A group photo taken at the EMBL Heidelberg site, showing members of EMBL and the Ruder Boskovic Institute

EMBL deepens ties with Croatia

Connections Visit of delegation from the Ruđer Bošković Institute to EMBL Heidelberg marks a new chapter in scientific and institutional cooperation

2022

connectionsevents

7 October 2022 A group of people at EMBL's partnership conference

The EMBL Connection

Connections EMBL's Partnership Conference highlights the value of its networks, bringing researchers together to build new scientific connections.

2022

connectionsevents

20 September 2022 8 representatives of both the Dieter Schwarz Foundation and EMBL are standing in the EMBL Imaging Centre foyer facing the camera

Life Science Alliance starts new chapter

ConnectionsLab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.

2022

connectionslab-matters

5 July 2022 A view of the EMBL Imaging Centre with fields in the background

The EMBL Imaging Centre: making it happen

Connections Creating a cutting-edge facility for the global life science community doesn't happen overnight. We spoke to some of those who worked to turn this dream into a reality.

2022

connectionsevents

8 June 2022 Two female scientists shown against a green background

2022 EMBL Alumni Awards Winners announced

EMBL Announcements Two former EMBL staff members have been recognised for their outstanding contributions to research in the fields of brain evolution and cancer.

2022

alumniembl-announcements

7 June 2022 Female scientist photographed in a garden

Welcome: Pascale Cossart

Lab MattersPeople & Perspectives Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.

2022

lab-matterspeople-perspectives

3 June 2022 he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

Shaping up the genome for cell division

Science & Technology Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.

2022

sciencescience-technology

10 May 2022

Royal Society honour for Eileen Furlong

EMBL AnnouncementsLab Matters EMBL’s Head of Genome Biology announced as Fellow of the Royal Society for her exceptional contributions to science.

2022

embl-announcementslab-matters

6 May 2022 Drawing of two chromosomes in which a highlighted area is switched around.

Flip-flop genome

Science & Technology Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.

2022

sciencescience-technology

5 May 2022 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

Enabling imaging across scales

EMBL Announcements EMBL’s first Imaging Centre Symposium will occur onsite at EMBL and include tours of the new Imaging Centre on 31 May, introducing participants to the facility and its staff and featuring talks on the rapid developments in imaging technologies that have led to notable biological and medical…

2022

embl-announcementsevents

6 April 2022 Portrait photo of Matthias Hentze surrounded by a colourful background

Matthias Hentze receives Centenary Award

EMBL AnnouncementsLab Matters EMBL Heidelberg’s Matthias Hentze receives the Biochemical Society’s Centenary Award for his discoveries in RNA biology.

2022

embl-announcementslab-matters

23 March 2022 Two Drosophila embryos stained with fluorescent dye on a purple background that indicates either solid or liquid state

From liquid to solid to drive development

Science & Technology Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.

2022

sciencescience-technology

20 March 2022 Portrait photo of EMBL Group Leader Judith Zaugg against a green background.

Judith Zaugg from EMBL Heidelberg receives ERC Consolidator Grant

EMBL AnnouncementsLab Matters Judith Zaugg, Group Leader at EMBL Heidelberg, has been awarded an ERC Consolidator Grant of €2 million funded under the European Union’s Horizon Europe research and innovation programme. Over the next five years, the grant will enable her group to study cellular interactions in the human bone…

2022

embl-announcementslab-matters

4 March 2022 Science art expressing the concept of transcriptional neighbourhoods regulating transcript isoform lengths and expression levels.

Understanding genomes, piece by piece

Science & Technology Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.

2022

sciencescience-technology

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science & Technology A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

sciencescience-technology

2 March 2022 Image composition showing a building with sun reflecting off the glass and microscopy images of microorganisms in multiple colours.

‘The World of Molecular Biology’ exhibition

EMBL AnnouncementsLab Matters The new permanent ‘The World of Molecular Biology’ exhibition will open in mid-2023 at EMBL’s headquarters in Heidelberg. It will encourage people to actively engage with science and its relevance for everyday life.

2022

embl-announcementslab-matters

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

23 February 2022 A male scientist in a white shirt stands at a walkway railing.

Welcome: Michael Dorrity

Lab MattersPeople & Perspectives Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.

2022

lab-matterspeople-perspectives

9 December 2021 Portrait photo of Eileen Furlong against blue-green background.

Eileen Furlong honoured with Leibniz Prize

EMBL AnnouncementsLab Matters EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).

2021

embl-announcementslab-matters

8 December 2021 An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

The impact of drugs on gut microbes is greater than we thought

Science & Technology Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…

2021

sciencescience-technology

12 November 2021 Pia Lavriha and Anna Steyer look at cryo-electron microscopic images on a computer screen.

EMBL Imaging Centre welcomes first external user

Lab MattersScience & Technology Correlative microscopy service enables PhD student from Switzerland to study structure and location of proteins cells use to communicate.

2021

lab-mattersscience-technology

5 November 2021 A headshot photo of Ken Holmes from July 2021

Ken Holmes

People & Perspectives Ken Holmes, outstanding pioneer of structural biology and founder of EMBL´s Hamburg site, died on 2 November 2021 at the age of 87.

2021

alumnipeople-perspectives

5 November 2021 Three-dimensional rendering of sponge neuroid cells (coloured orange) and sponge digestive cells (coloured green).

More than a gut reaction

Science & Technology What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.

2021

sciencescience-technology

13 October 2021 Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Tackling the collateral damage from antibiotics

Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…

2021

sciencescience-technology

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

sciencescience-technology

30 September 2021

New microscopy technique makes deep in vivo brain imaging possible

Science & Technology Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.

2021

sciencescience-technology

9 September 2021 Portrait of former EMBL Director General Iain Mattaj

German Cross of Merit for former EMBL Director General

EMBL Announcements Former EMBL Director General Professor Iain Mattaj was awarded the German Cross of Merit (‘Verdienstkreuz 1. Klasse des Verdienstordens der Bundesrepublik Deutschland’) at a ceremony held at EMBL Heidelberg on 9 September 2021.

2021

alumniembl-announcements

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

2021

sciencescience-technology

12 August 2021 Edith Heard's photo portrait in a circle in the middle of the image.

Edith Heard elected to the German National Academy of Sciences Leopoldina

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected a member of the German National Academy of Sciences Leopoldina. Her admission to the ‘Human Genetics and Molecular Medicine’ section recognises her outstanding professional contributions to science.

2021

embl-announcementslab-matters

20 July 2021 Dark grey bird sitting on a metal lamp post. Grass and rock in the background.

A black redstart visits

Lab Matters Mehdi Khadraoui, a former member of the EMBL Communications team, took this close-up of a black redstart.

2021

lab-matters

13 July 2021 From right to left, Ilaria Piazza and Ken Holmes’ portraits are side by side in circles on a greenish background

EMBL Alumni Awards 2021

People & Perspectives EMBL alumni Ilaria Piazza and Ken Holmes have been recognised for their outstanding contributions, and will receive their awards as part of the celebrations for EMBL World Alumni Day.

2021

alumnipeople-perspectives

17 June 2021 Three researchers surround microscopy equipment in a dark room with red lighting.

Illuminating protein complexes in cells

Lab MattersPeople & Perspectives EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.

2021

lab-matterspeople-perspectives

4 June 2021 Man in white shirt and blue jeans standing on a terrace in front of trees, facing the camera.

The power of community

Lab MattersPeople & Perspectives EMBL Director Matthias Hentze describes the Environmental Research Initiative: a community effort to solve global environmental challenges.

2021

lab-matterspeople-perspectives

1 June 2021 Two purple and white spheres against dark background.

Nuclear twins

Science & Technology Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.

2021

picture-of-the-weekscience-technology

27 April 2021 Three irregular shapes, made up of green, blue, red and pink speckles, are set against a black background.

SARS-CoV-2 curtails immune response in the gut

Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.

2021

sciencescience-technology

13 April 2021 EMBL Heidelberg's main building, the top of the façade lit up by sunlight.

Morning sun

Lab Matters Throwback to June 2014: While EMBL Heidelberg’s main entrance is still in the dark, the well-known EMBL logo is already lit by the morning sun.

2021

lab-matterspicture-of-the-week

9 March 2021 Wolfgang Huber faces the camera smiling

Wolfgang Huber becomes ISCB Fellow

EMBL AnnouncementsLab Matters The contribution of EMBL Group Leader and Senior Scientist Wolfgang Huber has been recognised by the International Society for Computational Biology

2021

embl-announcementslab-matters

26 February 2021 Woman with long brown hair stands in front of snow scene with arms crossed in front of her.

Welcome: Sinem Saka

Lab MattersPeople & Perspectives As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological puzzles.

2021

lab-matterspeople-perspectives

9 February 2021 An artistic representation of how bioinformatics allows study of the SARS-CoV-2 infection process. On the left, coronaviruses are approaching a human face contour. On the right, protein structures and a network of connections represent bioinformatic analysis.

Protein sequences provide clues to how SARS-CoV-2 infects cells

Science & Technology Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

2021

sciencescience-technology

27 January 2021 Nicoletta Petridou looks towards the camera smiling, whilst standing in a science laboratory

Welcome: Nicoletta Petridou

Lab MattersPeople & Perspectives New group leader Nicoletta Petridou explains her fascination with the complexity of early embryo development, and how the interdisciplinary nature of EMBL will aid her research.

2021

lab-matterspeople-perspectives

15 January 2021 young man with beard and mustache stands in front of window with blurry background

Welcome: Olivier Duss

Lab MattersPeople & Perspectives One of EMBL’s newest group leaders, Olivier Duss, will explore how RNA folds into functional structures and how it works with proteins to control a diverse range of activities in the cell.

2021

lab-matterspeople-perspectives

12 January 2021 Three images showing close-ups of different EMBL facilitites.

EMBL becomes newest Instruct Centre

ConnectionsLab Matters EMBL’s sites in Grenoble, Hamburg, and Heidelberg form the newest Instruct Centre. The new centre offers users access to a broad range of state-of-the-art facilities.

2021

connectionslab-matters

9 December 2020 Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Heating proteins to understand how genes work

Science & Technology A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.

2020

sciencescience-technology

2 December 2020 The image is a green coloured cell, with a wild and textured surface which is composed of many different shapes and shadows.

Scratching the surface on cell differentiation

Science & Technology Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…

2020

sciencescience-technology

24 November 2020 Red loops on a black background are dotted with bright red flecks and pale blue ovals as part of a confocal microscope image of bone marrow cells.

A loopy baseline

Science & Technology Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit ‘loopy’.

2020

picture-of-the-weekscience-technology

22 October 2020 An artistic image of colorful wires connected to a could database.

EOSC: shaping Europe’s digital future

ConnectionsLab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.

2020

connectionslab-matters

1 October 2020 A group of people in an office are holding a videoconference. Some of the participants are wearing masks and gloves

Boosting the life sciences through alumni networks

Connections EMBL’s network of alumni plays a vital role in advancing the life sciences globally. EMBL provides research, services, and infrastructure that help former staff to do this effectively. For several years EMBL has been discovering more avenues to help the life sciences across Europe. A key part of…

2020

connectionsevents

24 September 2020 The conference key visual shows a variety of species engulfed by fire, reflecting the conference title, ‘Our House Is Burning: Scientific and Societal Responses to Mass Extinction’.

Dinosaurs, dodos, and the future of life on Earth

Science & Technology EMBL’s 21st Science and Society Conference will address scientific and societal responses to mass extinctions. Ahead of his keynote speech, renowned palaeontologist Mike Benton explains how looking into the deep past can give us vital insights into the future of life on Earth.

2020

eventsscience-technology

8 September 2020 This image shows sections of the brain organoids that have been derived from pluripotent stem cells. The increasing use of organoids like this one be key to advancing personalised medicine.

Achieving personalised therapeutics

Lab MattersScience & Technology A decadal roadmap points the way to cell-based medicine for Europe

2020

lab-mattersscience-technology

3 September 2020 Left: Slice of a cell in grey. Right: Two 3D reconstructions of parts of the slice, showing the internal structure.

Nuclear pores in their natural context

Science & Technology Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.

2020

sciencescience-technology

24 August 2020 Simone Mattei, the new team leader in electron microscopy service and technology development

Welcome: Simone Mattei

Lab MattersPeople & Perspectives The new team leader offering services in electron microscopy discusses his hopes and plans for the forthcoming EMBL Imaging Centre

2020

lab-matterspeople-perspectives

19 August 2020 An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

Science & Technology Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.

2020

sciencescience-technology

31 July 2020 This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

Science & Technology A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.

2020

sciencescience-technology

28 July 2020 Atomic model of the entire condensin complex

Understanding chromosome organisation

Science & Technology EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.

2020

sciencescience-technology

21 July 2020 Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

A tool to improve cancer research

Science & Technology EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.

2020

sciencescience-technology

16 July 2020 A collage of portrait photos of Jessica Vamathevan, Jan Korbel, and Nassos Typas.

Changes in senior roles at EMBL

EMBL AnnouncementsLab Matters Three changes in senior staff positions have been confirmed at EMBL today. Jessica Vamathevan becomes Head of Strategy, Jan Korbel becomes Head of Data Science for EMBL Heidelberg, and Nassos Typas becomes Senior Scientist.

2020

embl-announcementslab-matters

8 July 2020 Alexander Aulehla on the left and Paul Flicek on the Right

Two EMBL scientists become EMBO Members

EMBL AnnouncementsLab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.

2020

embl-announcementslab-matters

3 July 2020 stem cells neurons differentiation

From stem cells to neurons

Science & Technology Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…

2020

sciencescience-technology

16 June 2020 Tissue culture plates in an incubator.

Understanding how SARS-CoV-2 behaves in the gut

Science & Technology Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…

2020

sciencescience-technology

22 May 2020

The hunt for neutralising antibodies against SARS-CoV-2

Science & Technology Scientists hope that a legacy of the novel coronavirus in recovered COVID-19 patients – antibodies in their blood – could lead to drugs to treat others. The Merten group at EMBL Heidelberg has pivoted its microfluidics platform to support the search for neutralising antibodies that could…

2020

sciencescience-technology

16 April 2020 Micropipette tips in a liquid-handling robot

Helping to scale up coronavirus testing

Science & Technology Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.

2020

sciencescience-technology

24 March 2020

Springtime in Heidelberg

Lab Matters The iconic ATC – celebrating its 10 year anniversary this year – reflects the blue sky, the clouds and the rays of the Sun.

2020

lab-matterspicture-of-the-week

17 March 2020

Wrapped in purple

Science & Technology The medaka shown in this Picture of the Week was captured by Eva Hasel, a postdoc in the Leptin group at EMBL Heidelberg.

2020

picture-of-the-weekscience-technology

11 July 2019 Structure of the Elongator complex

A tRNA modifier at work

Science & Technology Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.

2019

sciencescience-technology

11 February 2016 The 3D structure shows how two transcription factors influence one another’s binding to a specific stretch of DNA – an interaction that is crucial for a heart to develop healthily. IMAGE: EMBL/C.Müller

True Love

Science & Technology How transcription factors interact to create a heart

2016

sciencescience-technology

16 July 2015

Oskar’s structure revealed

Science & Technology 3D structure of Oskar protein gives first molecular insight into how it functions.

2015

sciencescience-technology

11 March 2011

Small code change, big effect

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method which enables researchers to label any protein of their choice with any of a wide variety of previously available compounds, in living cells, by introducing a single reactive…

2011

sciencescience-technology

6 March 2011 By silencing genes two at a time in cells like these, the scientists can analyse the genes’ combined effects. In this microscopy image of human cells, nuclei are shown in red, cell membranes in green, and the cellular scaffolding in blue.

Suggesting genes’ friends, facebook-style

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can…

2011

sciencescience-technology

4 March 2011 Máire Geoghegan-Quinn, European Commissioner for Research, Innovation and Science, and Iain Mattaj, Director-General of EMBL, signing the Memorandum of Understanding.

European Commission and EMBL renew cooperation

Lab Matters In a Memorandum of Understanding signed today, the European Commission (EC) and the European Molecular Biology Laboratory (EMBL) formalise their desire to maintain and further develop their cooperation. “I am delighted to sign the renewed and strengthened Memorandum of Understanding between the…

2011

lab-matters

23 January 2011 Micropilot detected cells at particular stages of cell division

Intelligent microscopy

Science & Technology The sight of a researcher sitting at a microscope for hours, painstakingly searching for the right cells, may soon be a thing of the past, thanks to new software created by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Presented today in Nature Methods, the…

2011

sciencescience-technology

4 July 2010 The Fly Digital Embryo at different developmental stages, with cell nuclei coloured according to how fast they were moving (from blue for the slowest to orange for the fastest). The fruit fly embryo is magnified around 250 times. IMAGE: Philipp Keller

Digital Embryo gains wings

Science & Technology The scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, who ‘fathered’ the Digital Embryo have now given it wings, creating the Fly Digital Embryo. In work published today in Nature Methods, they were able to capture fruit fly development on film, and were the…

2010

sciencescience-technology

24 June 2010 These microscopy images show that a protein from the NSL complex (green) and MOF (red) both bind to all chromosomes in male (right) and female (left) fruit flies - overlap is shown in purple. On the male X chromosome, MOF binds not only to promoter regions but also to the body of the genes, generating a brighter signal (pink). Image credits: Akhtar/EMBL.

A life-changing partnership

Science & Technology Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…

2010

sciencescience-technology

2 May 2010 These microscopy images show the region of the embryo larva that will develop into the adult fruit fly’s wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) - a situation which is corrected when PR-DUB’s activity is restored (right). Image credits: J.Mueller/EMBL.

Tags on, tags off

Science & Technology During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing specialised tissues and organs from forming in the wrong places. They also play an important role in processes like stem cell differentiation and…

2010

sciencescience-technology

1 April 2010 Each of these large images of dividing cells is composed of several microscopy images of human cells in which different individual genes were silenced. The smaller images are placed according to genes’ effects: images for genes that affect chromosomes make up the chromosomes (red/pink), while the mitotic spindle (green) is composed of images for genes that affect it. IMAGE: Thomas Walter & Mayumi Isokane / EMBL

Movies for the human genome

Science & Technology Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…

2010

sciencescience-technology

9 March 2010 The new EMBL Advanced Training Centre in Heidelberg, Germany. PHOTO: Hugo Nevers/EMBL

New training and conference centre for the life sciences at EMBL in Heidelberg

Lab Matters Today, the German Minister for Education and Research, Annette Schavan, officially opens the new training and conference centre for the life sciences on the campus of the European Molecular Biology Laboratory (EMBL) in Heidelberg. “This new centre in Heidelberg will form a central European…

2010

lab-matters

19 January 2010 Image credit: Rachel Melwig & Christine Panagiotidis / EMBL

Membrane-coat proteins: bacteria have them too

Science & Technology Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…

2010

sciencescience-technology

10 December 2009 These microscopy images show the cellular reprogramming uncovered by EMBL scientists. On the left is an ovary of a normal adult female mouse, with a close-up (top left) showing the typical female granulosa cells. When the Foxl2 gene was silenced in these cells (right, top right: close-up), they took on the characteristics of Sertoli cells, the cells normally found in testes of male mice. Image credit: Treier / EMBL

The Battle of the Sexes

Science & Technology Is it a boy or a girl? Expecting parents may be accustomed to this question, but contrary to what they may think, the answer doesn’t depend solely on their child’s sex chromosomes. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and the Medical Research…

2009

sciencescience-technology

30 September 2009 In the centre, a structural model determined by X-ray crystallography shows how the two tags (attached to a short section of the histone protein – all in cyan) fit neatly into the Brdt pocket (purple). In the background image, hypercompaction by Brdt causes relatively diffuse chromatin (stained blue inside the nuclei of two cells on the top left) to compact and clump together (two on the bottom right).

Putting the squeeze on sperm DNA

Science & Technology In the quest for speed, olympic swimmers shave themselves or squeeze into high-tech super-suits. In the body, sperm are the only cells that swim and, as speed is crucial to fertility, have developed their own ways to become exceptionally streamlined. Scientists at the European Molecular Biology…

2009

sciencescience-technology

13 August 2009

Raising the alarm when DNA goes bad

Science & Technology Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. Scientists have known for a long time that when DNA is damaged, a key enzyme sets off a cellular ‘alarm bell’ to alert the…

2009

sciencescience-technology

2 August 2009

Scientists open doors to diagnosis of emphysema

Science & Technology Chronic inflammatory lung diseases like chronic bronchitis and emphysema are a major global health problem, and the fourth leading cause of death and disability in developed countries, with smoking accounting for 90% of the risk for developing them. Work by scientists at the European Molecular…

2009

sciencescience-technology

7 July 2009

Scientists identify cholesterol-regulating genes

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published today in the journal Cell Metabolism, the researchers identified 20 genes that are involved…

2009

sciencescience-technology

25 June 2009 The microscope image of the dorsal closure of a fly embryo shows alternating stripes of epithelial cells with aligned microtubule bundles (green) and epithelial cells treated with a microtubule-destroying drug (blue). Labelled in red is the protein actin that lines the border of cells, particularly the amnioserosa cells occupying the eye-shaped opening.

Uncovering how cells cover gaps

Science & Technology Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study, published this week in the journal Cell, uncovers a fundamental…

2009

sciencescience-technology

23 June 2009 Lattice maps for immature HIV particles. The 3D computer reconstruction shows the immature Gag lattice of HIV that matures to form the protein shell of the infecious virus. Maps are shown in perspective such that hexamers on the rear surface of the particle appear smaller. The side of the particle toward the viewer lacks ordered Gag. IMAGE: John Briggs/EMBL

New electron microscopy images reveal the assembly of HIV

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is…

2009

sciencescience-technology

9 June 2009 Reflect applied to a pubmed webpage. Protein names found in the text are highlighted in blue, chemicals in orange. Pop-up windows provide extra information on the biomolecules.

New EMBL service makes web browsing efficient for biologists

Science & Technology The life sciences are scaling up and produce huge amounts of data and new literature at an amazing pace. The European Molecular Biology Laboratory (EMBL) now offers a new free service to help researchers, teachers and students keep up-to-date with scientific literature on the web, especially when…

2009

sciencescience-technology

28 May 2009

Sugarcoating fruit fly development

Science & Technology Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…

2009

sciencescience-technology

23 April 2009

New study reveals the protein that makes phosphate chains in yeast

Science & Technology It can be found in all life forms, and serves a multitude of purposes, from energy storage to stress response to bone calcification. This molecular jack-of-all trades is polyphosphate, a long chain of phosphate molecules. Researchers at the European Molecular Biology Laboratory (EMBL) in…

2009

sciencescience-technology

24 February 2009 A full body shot of Medaka juveniles, taken by Philipp Keller, from the lab of Ernst Stelzer at the European Molecular Biology Laboratory (EMBL), with a newly developed microscope called Digital Scanned Laser Light Sheet Fluorescence Microscope. Picture credits: Philipp Keller, Stelzer Group, EMBL

Picture Release

Science & Technology ‘Useless fish with big eyes’. This is what Medaka, the name of the Japanese killifish in the pictures, means in Japan where it originally comes from. While its eyes are undeniably big, the fish has proven remarkably useful for scientists. It is a simple model organism, amenable to…

2009

sciencescience-technology

25 January 2009

Re-write the textbooks: transcription is bidirectional

Science & Technology Genes that contain instructions for making proteins make up less than 2% of the human genome. Yet, for unknown reasons, most of our genome is transcribed into RNA. The same is true for many other organisms that are easier to study than humans. Researchers in the groups of Lars Steinmetz at the…

2009

sciencescience-technology

EMBLetc.

Looking for past print editions of EMBLetc.? Browse our archive, going back 20 years.

EMBLetc. archive

Newsletter archive

Read past editions of our e-newsletter

For press

Contact the Press Office
Edit