People & Perspectives Jan Bláha, postdoc at EMBL Hamburg, talks about the utility of in cellulo protein crystallisation in structural biology research, his sources of inspiration, and the values of collaboration, curiosity, and resilience.
2024
people-perspectives
Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…
2024
science-technology
Science & Technology An interdisciplinary collaboration between Hamburg scientists has yielded new insights into the structure and function of a heat-resistant enzyme from an exotic microbe. In this interview, EMBL Hamburg’s Matthias Wilmanns and TUHH’s Garo Antranikian discuss how their collaboration developed and…
2023
sciencescience-technology
Lab MattersPeople & Perspectives In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.
2023
lab-matterspeople-perspectives
Science & Technology EMBL Hamburg scientists have contributed to the development of the Spitrobot, a ground-breaking experimental setup that will simplify creating molecular movies. The Spitrobot automates the sample preparation for time-resolved crystallography, which is used to create 3D snapshots of protein…
2023
sciencescience-technology
Science & Technology EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.
2022
sciencescience-technology
Science & Technology EMBL Hamburg’s Wilmanns and Kosinski groups have determined the detailed structure of a bacterial protein complex critical for tuberculosis infection.
2021
sciencescience-technology
Science & Technology A new paper describes a unique mechanism of partner selectivity in transcription factors.
2019
sciencescience-technology
Science & Technology Suicide system in tuberculosis bacteria might hold key to treatment
2019
sciencescience-technology
Science & Technology EMBL scientists investigate the structure of a key protein involved in blood clotting
2018
sciencescience-technology
Science & Technology EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
sciencescience-technology
Science & Technology How cells eliminate protein deposits that can lead to neurodegenerative disorders
2016
sciencescience-technology
Science & Technology Unexpected results: structure of DAPK enzyme reveals dual-purpose loop
2016
sciencescience-technology
Science & Technology How an EMBL team is making and sharing tools to explore tuberculosis protein structures
2016
sciencescience-technology
Science & Technology Hamburg collaborators analyse protein crystals inside the cells that made them.
2016
sciencescience-technology
Science & Technology In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The new findings…
2011
sciencescience-technology
Science & Technology Cells rely on a range of signalling systems to communicate with each other and to control their own internal workings. Scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, have now found a way to hack into a vital communications system, raising the possibility of…
2010
sciencescience-technology
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