{"id":13199,"date":"2023-04-17T11:53:00","date_gmt":"2023-04-17T11:53:00","guid":{"rendered":"https:\/\/www.embl.org\/groups\/zaugg\/?p=13199"},"modified":"2024-02-27T11:59:23","modified_gmt":"2024-02-27T11:59:23","slug":"paper-on-enhancer-mediated-gene-regulatory-network-inference-is-out","status":"publish","type":"post","link":"https:\/\/www.embl.org\/groups\/zaugg\/blog\/2023\/04\/paper-on-enhancer-mediated-gene-regulatory-network-inference-is-out\/","title":{"rendered":"Paper on enhancer-mediated gene regulatory network inference is out!"},"content":{"rendered":"\n<p>This work describes our methods for inferring enhancer-mediated gene regulatory networks and how we can use these networks to identify transcription factors that drive differential expression between two conditions.<\/p>\n\n\n\n<p>Congratulations to Aryan, Christian and all the co-authors (this has been a massive group effort with many people from the Zaugg group contributing essential analyses)! <\/p>\n\n\n\n<p>Check it out here: <a href=\"https:\/\/www.embopress.org\/doi\/full\/10.15252\/msb.202311627\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/www.embopress.org\/doi\/full\/10.15252\/msb.202311627<\/a><\/p>\n\n\n\n<h3 class=\"wp-block-heading\">GRaNIE and GRaNPA: inference and evaluation of enhancer-mediated gene regulatory networks.<\/h3>\n\n\n\n<p>Kamal A*, Arnold C*, Claringbould A, Moussa R, Servaas NH, Kholmatov M, Daga N, Nogina D, Mueller-Dott S, Reyes-Palomares A, Palla G, Sigalova O, Bunina D, Pabst C, Zaugg JB<\/p>\n\n\n\n<p>Molecular systems biology,&nbsp;2023<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This work describes our methods for inferring enhancer-mediated gene regulatory networks and how we can use these networks to identify transcription factors that drive differential expression between two conditions. Congratulations to Aryan, Christian and all the co-authors (this has been a massive&hellip;<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"embl_taxonomy":[],"class_list":["post-13199","post","type-post","status-publish","format-standard","hentry","category-general"],"acf":[],"embl_taxonomy_terms":[],"featured_image_src":"https:\/\/www.embl.org\/groups\/zaugg\/wp-includes\/images\/media\/default.svg","_links":{"self":[{"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/posts\/13199","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/comments?post=13199"}],"version-history":[{"count":1,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/posts\/13199\/revisions"}],"predecessor-version":[{"id":13203,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/posts\/13199\/revisions\/13203"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/media?parent=13199"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/categories?post=13199"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/tags?post=13199"},{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/zaugg\/wp-json\/wp\/v2\/embl_taxonomy?post=13199"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}