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Svergun Group

Small-angle X-ray scattering from macromolecular solutions

Publications

Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2.

Abdul Rehman SA, Armstrong LA, Lange SM, Kristariyanto YA, Gräwert TW, Knebel A, Svergun DI, Kulathu Y

Molecular cell 2021

doi:10.1016/j.molcel.2021.08.024.

Structure and dynamics of UBA5-UFM1 complex formation showing new insights in the UBA5 activation mechanism.

Fuchs S, Kikhney AG, Schubert R, Kaiser C, Liebau E, Svergun DI, Betzel C, Perbandt M

Journal of structural biology 2021

doi:10.1016/j.jsb.2021.107796.

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.

Benedyk TH, Muenzner J, Connor V, Han Y, Brown K, Wijesinghe KJ, Zhuang Y, Colaco S, Stoll GA, Tutt OS, Svobodova S, Svergun DI, Bryant NA, Deane JE, Firth AE, Jeffries CM, Crump CM, Graham SC

PLoS pathogens 2021

doi:10.1371/journal.ppat.1009824.

ASAXS measurements on ferritin and apoferritin at the bioSAXS beamline P12 (PETRA III, DESY).

Wieland DCF, Schroer MA, Gruzinov AY, Blanchet CE, Jeffries CM, Svergun DI

Journal of applied crystallography 2021

doi:10.1107/S1600576721003034.

Molecular model of a sensor of two-component signaling system.

Ryzhykau YL, Orekhov PS, Rulev MI, Vlasov AV, Melnikov IA, Volkov DA, Nikolaev MY, Zabelskii DV, Murugova TN, Chupin VV, Rogachev AV, Gruzinov AY, Svergun DI, Brennich ME, Gushchin IY, Soler-Lopez M, Bothe A, Büldt G, Leonard G, Engelhard M, Kuklin AI, Gordeliy VI

Scientific reports 2021

doi:10.1038/s41598-021-89613-6.

Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation.

Soni K, Kempf G, Manalastas-Cantos K, Hendricks A, Flemming D, Guizetti J, Simon B, Frischknecht F, Svergun DI, Wild K, Sinning I

Communications biology 2021

doi:10.1038/s42003-021-02132-y.

Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis.

Lizarrondo J, Klebl DP, Niebling S, Abella M, Schroer MA, Mertens HDT, Veith K, Thuenauer R, Svergun DI, Skruzny M, Sobott F, Muench SP, Garcia-Alai MM

Nature communications 2021

doi:10.1038/s41467-021-23151-7.

Autism associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses.

Bucher M, Niebling S, Han Y, Molodenskiy D, Nia FH, Kreienkamp HJ, Svergun D, Kim E, Kostyukova AS, Kreutz MR, Mikhaylova M

eLife 2021

doi:10.7554/eLife.66165.

Anomalous SAXS at P12 beamline EMBL Hamburg: instrumentation and applications.

Gruzinov AY, Schroer MA, Manalastas-Cantos K, Kikhney AG, Hajizadeh NR, Schulz F, Franke D, Svergun DI, Blanchet CE

Journal of synchrotron radiation 2021

doi:10.1107/S1600577521003404.

Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes.

Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C

Science advances 2021

doi:10.1126/sciadv.abf1004.

Molecular basis of F-actin regulation and sarcomere assembly via myotilin.

Kostan J, Pavšič M, Puž V, Schwarz TC, Drepper F, Molt S, Graewert MA, Schreiner C, Sajko S, van der Ven PFM, Onipe A, Svergun DI, Warscheid B, Konrat R, Fürst DO, Lenarčič B, Djinović-Carugo K

PLoS biology 2021

doi:10.1371/journal.pbio.3001148.

Author Correction: self-assembly and regulation of protein cages from pre-organised coiled-coil modules.

Lapenta F, Aupič J, Vezzoli M, Strmšek Ž, Da Vela S, Svergun DI, Carazo JM, Melero R, Jerala R

Nature communications 2021

doi:10.1038/s41467-021-21969-9.

Comment on the optimal parameters to derive intrinsically disordered protein conformational ensembles from small-angle X-ray scattering data using the ensemble optimization method.

Sagar A, Jeffries CM, Petoukhov MV, Svergun DI, Bernadó P

Journal of chemical theory and computation 2021

doi:10.1021/acs.jctc.1c00014.

Self-assembly and regulation of protein cages from pre-organised coiled-coil modules.

Lapenta F, Aupič J, Vezzoli M, Strmšek Ž, Da Vela S, Svergun DI, Carazo JM, Melero R, Jerala R

Nature communications 2021

doi:10.1038/s41467-021-21184-6.

Limitations of the iterative electron density reconstruction algorithm from solution scattering data.

Konarev PV, Svergun DI

Nature methods 2021

doi:10.1038/s41592-021-01082-x.

MPBuilder: a PyMOL plugin for building and refinement of solubilized membrane proteins against small angle X-ray scattering data.

Molodenskiy D, Svergun D, Mertens H

Journal of molecular biology 2021

doi:10.1016/j.jmb.2021.166888.

The allosteric modulation of Complement C5 by knob domain peptides.

Macpherson A, Laabei M, Ahdash Z, Graewert MA, Birtley JR, Schulze ME, Crennell S, Robinson SA, Holmes B, Oleinikovas V, Nilsson PH, Snowden J, Ellis V, Mollnes TE, Deane CM, Svergun D, Lawson AD, van den Elsen JM

eLife 2021

doi:10.7554/eLife.63586.

Restoring structural parameters of lipid mixtures from small-angle X-ray scattering data.

Konarev PV, Gruzinov AY, Mertens HDT, Svergun DI

Journal of applied crystallography 2021

doi:10.1107/S1600576720015368.

ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis.

Manalastas-Cantos K, Konarev PV, Hajizadeh NR, Kikhney AG, Petoukhov MV, Molodenskiy DS, Panjkovich A, Mertens HDT, Gruzinov A, Borges C, Jeffries CM, Svergun DI, Franke D

Journal of applied crystallography 2021

doi:10.1107/S1600576720013412.

Methods, development and applications of small-angle X-ray scattering to characterize biological macromolecules in solution.

Da Vela S, Svergun DI

Current research in structural biology 2020

doi:10.1016/j.crstbi.2020.08.004.

Structural analyses of intrinsically disordered proteins by small-angle X-ray scattering.

Sagar A, Svergun D, Bernadó P

Methods in molecular biology (Clifton, N.J.) 2020

doi:10.1007/978-1-0716-0524-0_12.

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.

Sajko S, Grishkovskaya I, Kostan J, Graewert M, Setiawan K, Trübestein L, Niedermüller K, Gehin C, Sponga A, Puchinger M, Gavin AC, Leonard TA, Svergun DI, Smith TK, Morriswood B, Djinovic-Carugo K

PloS one 2020

doi:10.1371/journal.pone.0242677.

PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins.

Lazar T, Martínez-Pérez E, Quaglia F, Hatos A, Chemes LB, Iserte JA, Méndez NA, Garrone NA, Saldaño TE, Marchetti J, Rueda AJV, Bernadó P, Blackledge M, Cordeiro TN, Fagerberg E, Forman-Kay JD, Fornasari MS, Gibson TJ, Gomes GW, Gradinaru CC, Head-Gordon T, Jensen MR, Lemke EA, Longhi S, Marino-Buslje C, Minervini G, Mittag T, Monzon AM, Pappu RV, Parisi G, Ricard-Blum S, Ruff KM, Salladini E, Skepö M, Svergun D, Vallet SD, Varadi M, Tompa P, Tosatto SCE, Piovesan D

Nucleic acids research 2020

doi:10.1093/nar/gkaa1021.

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.

Custódio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hällberg BM, Löw C

Nature communications 2020

doi:10.1038/s41467-020-19204-y.

Adding size exclusion chromatography (SEC) and light scattering (LS) devices to obtain high-quality small angle X-ray scattering (SAXS) data.

Graewert MA, Da Vela S, Gräwert TW, Molodenskiy DS, Blanchet CE, Svergun DI, Jeffries CM

2020

doi:10.3390/cryst10110975.

Investigation of pH-responsiveness inside lipid nanoparticles for parenteral mRNA application using small-angle X-ray scattering.

Uebbing L, Ziller A, Siewert C, Schroer MA, Blanchet CE, Svergun DI, Ramishetti S, Peer D, Sahin U, Haas H, Langguth P

Langmuir : the ACS journal of surfaces and colloids 2020

doi:10.1021/acs.langmuir.0c02446.

A giant extracellular matrix binding protein of staphylococcus epidermidis binds surface-immobilized fibronectin via a novel mechanism.

Büttner H, Perbandt M, Kohler T, Kikhney A, Wolters M, Christner M, Heise M, Wilde J, Weißelberg S, Both A, Betzel C, Hammerschmidt S, Svergun D, Aepfelbacher M, Rohde H

mBio 2020

doi:10.1128/mBio.01612-20.

Structural role of essential light chains in the apicomplexan glideosome.

Pazicky S, Dhamotharan K, Kaszuba K, Mertens HDT, Gilberger T, Svergun D, Kosinski J, Weininger U, Löw C

Communications biology 2020

doi:10.1038/s42003-020-01283-8.

Capturing the conformational ensemble of the mixed folded polyglutamine Protein Ataxin-3.

Sicorello A, Różycki B, Konarev PV, Svergun DI, Pastore A

Structure (London, England : 1993) 2020

doi:10.1016/j.str.2020.09.010.

The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering.

Kukkurainen S, Azizi L, Zhang P, Jacquier MC, Baikoghli M, von Essen M, Tuukkanen A, Laitaoja M, Liu X, Rahikainen R, Orłowski A, Jänis J, Määttä JAE, Varjosalo M, Vattulainen I, Róg T, Svergun D, Cheng RH, Wu J, Hytönen VP, Wehrle-Haller B

Journal of cell science 2020

doi:10.1242/jcs.239202.

Hybrid biopolymer and lipid nanoparticles with improved transfection efficacy for mRNA.

Siewert CD, Haas H, Cornet V, Nogueira SS, Nawroth T, Uebbing L, Ziller A, Al-Gousous J, Radulescu A, Schroer MA, Blanchet CE, Svergun DI, Radsak MP, Sahin U, Langguth P

Cells 2020

doi:10.3390/cells9092034.

Rapid screening of in cellulo grown protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach.

Lahey-Rudolph JM, Schönherr R, Jeffries CM, Blanchet CE, Boger J, Ferreira Ramos AS, Riekehr WM, Triandafillidis DP, Valmas A, Margiolaki I, Svergun D, Redecke L

Journal of applied crystallography 2020

doi:10.1107/S1600576720010687.

Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery.

Nogueira SS, Schlegel A, Maxeiner K, Weber B, Barz M, Schroer MA, Blanchet CE, Svergun DI, Ramishetti S, Peer D, Langguth P, Sahin U, Haas H

{ACS} Applied Nano Materials 2020

doi:10.1021/acsanm.0c01834.

Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.

Osz J, McEwen AG, Bourguet M, Przybilla F, Peluso-Iltis C, Poussin-Courmontagne P, Mély Y, Cianférani S, Jeffries CM, Svergun DI, Rochel N

Nucleic acids research 2020

doi:10.1093/nar/gkaa697.

RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.

Knittel V, Sadana P, Seekircher S, Stolle AS, Körner B, Volk M, Jeffries CM, Svergun DI, Heroven AK, Scrima A, Dersch P

PLoS pathogens 2020

doi:10.1371/journal.ppat.1008552.

A THz transparent 3D printed microfluidic cell for small angle x-ray scattering.

Schewa S, Schroer MA, Zickmantel T, Song YH, Blanchet CE, Gruzinov AY, Katona G, Svergun DI, Roessle M

REVIEW OF SCIENTIFIC INSTRUMENTS 2020

doi:10.1063/5.0004706.

Anomeric selectivity of trehalose transferase with rare L-sugars.

Mestrom L, Marsden SR, van der Eijk H, Laustsen JU, Jeffries CM, Svergun DI, Hagedoorn PL, Bento I, Hanefeld U

2020

doi:10.1021/acscatal.0c02117.

Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations.

Solomon-Degefa H, Gebauer JM, Jeffries CM, Freiburg CD, Meckelburg P, Bird LE, Baumann U, Svergun DI, Owens RJ, Werner JM, Behrmann E, Paulsson M, Wagener R

2020

doi:10.1074/jbc.RA120.014865.

The basics of small-angle neutron scattering (SANS for new users of structural biology).

Jeffries CM, Pietras Z, Svergun DI

EPJ Web of Conferences 2020

doi:10.1051/epjconf/202023603001.

Structure-based identification and functional characterization of a lipocalin in the malaria parasite Plasmodium falciparum.

Burda PC, Crosskey T, Lauk K, Zurborg A, Söhnchen C, Liffner B, Wilcke L, Pietsch E, Strauss J, Jeffries CM, Svergun DI, Wilson DW, Wilmanns M, Gilberger TW

Cell reports 2020

doi:10.1016/j.celrep.2020.107817.

An automated data processing and analysis pipeline for transmembrane proteins in detergent solutions.

Molodenskiy DS, Mertens HDT, Svergun DI

Scientific reports 2020

doi:10.1038/s41598-020-64933-1.

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.

Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC

eLife 2020

doi:10.7554/eLife.53789.

Btk SH2-kinase interface is critical for allosteric kinase activation and its targeting inhibits B-cell neoplasms.

Duarte DP, Lamontanara AJ, La Sala G, Jeong S, Sohn YK, Panjkovich A, Georgeon S, Kükenshöner T, Marcaida MJ, Pojer F, De Vivo M, Svergun D, Kim HS, Dal Peraro M, Hantschel O

Nature communications 2020

doi:10.1038/s41467-020-16128-5.

Tetrameric structures of inorganic CBS-pyrophosphatases from various bacterial species revealed by small-angle X-ray scattering in solution.

Dadinova LA, Soshinskaia EY, Jeffries CM, Svergun DI, Shtykova EV

Biomolecules 2020

doi:10.3390/biom10040564.

Simulation of small-angle X-ray scattering data of biological macromolecules in solution.

Franke D, Hajizadeh NR, Svergun DI

Journal of applied crystallography 2020

doi:10.1107/S1600576720000527.

Author correction: Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes.

Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z

Scientific reports 2020

doi:10.1038/s41598-020-61336-0.

Structural kinetics of MsbA investigated by stopped-flow time-resolved small-angle X-ray scattering.

Josts I, Gao Y, Monteiro DCF, Niebling S, Nitsche J, Veith K, Gräwert TW, Blanchet CE, Schroer MA, Huse N, Pearson AR, Svergun DI, Tidow H

Structure (London, England : 1993) 2019

doi:10.1016/j.str.2019.12.001.

Quasi-atomistic approach to modeling of liposomes.

Petukhov MV, Konarev PV, Dadinova LA, Fedorova NV, Volynsky PE, Svergun DI, Batishchev OV, Shtykova EV

CRYSTALLOGRAPHY REPORTS 2020

doi:10.1134/S1063774520020182.

Structural modeling using solution small-angle X-ray scattering (SAXS).

Gräwert TW, Svergun DI

Journal of molecular biology 2020

doi:10.1016/j.jmb.2020.01.030.

BILMIX: a new approach to restore the size polydispersity and electron density profiles of lipid bilayers from liposomes using small-angle X-ray scattering data.

Konarev PV, Petoukhov MV, Dadinova LA, Fedorova NV, Volynsky PE, Svergun DI, Batishchev OV, Shtykova EV

JOURNAL OF APPLIED CRYSTALLOGRAPHY 2020

doi:10.1107/S1600576719015656.

Molecular mechanisms of the interactions of N-(2-hydroxypropyl)methacrylamide copolymers designed for cancer therapy with blood plasma proteins.

Janisova L, Gruzinov A, Zaborova OV, Velychkivska N, Vaněk O, Chytil P, Etrych T, Janoušková O, Zhang X, Blanchet C, Papadakis CM, Svergun DI, Filippov SK

Pharmaceutics 2020

doi:10.3390/pharmaceutics12020106.

Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.

Trstenjak N, Milić D, Graewert MA, Rouha H, Svergun D, Djinović-Carugo K, Nagy E, Badarau A

Proceedings of the National Academy of Sciences of the United States of America 2019

doi:10.1073/pnas.1913690116.

SASBDB: towards automatically curated and validated repository for biological scattering data.

Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI

Protein science : a publication of the Protein Society 2019

doi:10.1002/pro.3731.

Structural properties of [2Fe-2S] ISCA2-IBA57: a complex of the mitochondrial iron-sulfur cluster assembly machinery.

Nasta V, Da Vela S, Gourdoupis S, Ciofi-Baffoni S, Svergun DI, Banci L

Scientific reports 2019

doi:10.1038/s41598-019-55313-5.

Effect of the concentration of protein and nanoparticles on the structure of biohybrid nanocomposites.

Majorošová J, Schroer MA, Tomašovičová N, Batková M, Hu PS, Kubovčíková M, Svergun DI, Kopčanský P

Biopolymers 2019

doi:10.1002/bip.23342.

Federating structural models and data: outcomes from a workshop on archiving integrative structures.

Berman HM, Adams PD, Bonvin AA, Burley SK, Carragher B, Chiu W, DiMaio F, Ferrin TE, Gabanyi MJ, Goddard TD, Griffin PR, Haas J, Hanke CA, Hoch JC, Hummer G, Lawson CL, Kurisu G, Markley JL, Leitner A, Montelione GT, Meiler J, Prisner T, Phillips GN, Schriemer DC, Rappsilber J, Seidel CAM, Schwede T, Svergun DI, Strutzenberg TS, Trewhella J, Tajkhorshid E, Vuister GW, Webb B, Vallat B, Velankar S, Sali A, Westbrook JD, White KL

Structure (London, England : 1993) 2019

doi:10.1016/j.str.2019.11.002.

The dimeric ectodomain of the alkali-sensing insulin receptor-related receptor (ectoIRR) has a drop-like shape.

Shtykova EV, Petoukhov MV, Mozhaev AA, Deyev IE, Dadinova LA, Loshkarev NA, Goryashchenko AS, Bocharov EV, Jeffries CM, Svergun DI, Batishchev OV, Petrenko AG

The Journal of biological chemistry 2019

doi:10.1074/jbc.RA119.010390.

Conformational characterization of full-length X-chromosome-linked inhibitor of apoptosis protein (XIAP) through an integrated approach.

Polykretis P, Luchinat E, Bonucci A, Giachetti A, Graewert MA, Svergun DI, Banci L

IUCrJ 2019

doi:10.1107/S205225251901073X.

Solution structure and flexibility of the condensin HEAT-repeat subunit Ycg1.

Manalastas-Cantos K, M, Haering CH, Svergun DI

The Journal of biological chemistry 2019

doi:10.1074/jbc.RA119.008661.

The quaternary structure of insulin glargine and glulisine under formulation conditions.

Nagel N, Graewert MA, Gao M, Heyse W, Jeffries CM, Svergun D, Berchtold, H.

2019

doi:10.1016/j.bpc.2019.106226.

Molecular organization of soluble type III secretion system sorting platform complexes.

Bernal I, Börnicke J, Heidemann J, Svergun D, Horstmann JA, Erhardt M, Tuukkanen A, Uetrecht C, Kolbe M

Journal of molecular biology 2019

doi:10.1016/j.jmb.2019.07.004.

Studying conformational changes of the Yersinia type-III-secretion effector YopO in solution by integrative structural biology.

Peter MF, Tuukkanen AT, Heubach CA, Selsam A, Duthie FG, Svergun DI, Schiemann O, Hagelueken G

Structure (London, England : 1993) 2019

doi:10.1016/j.str.2019.06.007.

Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.

Verschueren KHG, Blanchet C, Felix J, Dansercoer A, De Vos D, Bloch Y, Van Beeumen J, Svergun D, Gutsche I, Savvides SN, Verstraete K

Nature 2019

doi:10.1038/s41586-019-1095-5.

The free energy landscape of the oncogene protein E7 of human papillomavirus type 16 reveals a complex interplay between ordered and disordered regions.

Kukic P, Lo Piccolo GM, Nogueira MO, Svergun DI, Vendruscolo M, Felli IC, Pierattelli R

Scientific reports 2019

doi:10.1038/s41598-019-41925-4.

Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes.

Czech A, Konarev PV, Goebel I, Svergun DI, Wills PR, Ignatova Z

Scientific reports 2019

doi:10.1038/s41598-019-39213-2.

An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death.

Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Schnappinger D, Svergun DI, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O

Molecular cell 2019

doi:10.1016/j.molcel.2019.01.028.

Shedding light on the interaction of human anti-apoptotic Bcl-2 protein with ligands through biophysical and in silico studies.

Ramos J, Muthukumaran J, Freire F, Paquete-Ferreira J, Otrelo-Cardoso AR, Svergun D, Panjkovich A, Santos-Silva T

International journal of molecular sciences 2019

doi:10.3390/ijms20040860.

Molecular dissection of the intrinsically disordered estrogen receptor Alpha-NTD.

Manalastas KG, Svergun DI

Structure (London, England : 1993) 2019

doi:10.1016/j.str.2019.01.006.

Investigation of charge ratio variation in mRNA - DEAE-dextran polyplex delivery systems.

Siewert C, Haas H, Nawroth T, Ziller A, Nogueira SS, Schroer MA, Blanchet CE, Svergun DI, Radulescu A, Bates F, Huesemann Y, Radsak MP, Sahin U, Langguth P

Biomaterials 2018

doi:10.1016/j.biomaterials.2018.10.020.

Utilization of staphylococcal immune evasion protein Sbi as a novel vaccine adjuvant.

Yang Y, Back CR, Gräwert MA, Wahid AA, Denton H, Kildani R, Paulin J, Wörner K, Kaiser W, Svergun DI, Sartbaeva A, Watts AG, Marchbank KJ, van den Elsen JMH

Frontiers in immunology 2018

doi:10.3389/fimmu.2018.03139.

Human MICAL1: activation by the small GTPase Rab8 and small-angle X-ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8.

Esposito A, Ventura V, Petoukhov MV, Rai A, Svergun DI, Vanoni MA

Protein science : a publication of the Protein Society 2018

doi:10.1002/pro.3512.

Structural basis for activation of plasma-membrane Ca2+-ATPase by calmodulin.

Nitsche J, Josts I, Heidemann J, Mertens HD, Maric S, Moulin M, Haertlein M, Busch S, Forsyth VT, Svergun DI, Uetrecht C, Tidow H

Communications biology 2018

doi:10.1038/s42003-018-0203-7.

Probing the architecture of a multi-PDZ domain protein: structure of PDZK1 in solution.

Hajizadeh N, Pieprzyk J, Skopintsev P, Flayhan A, Svergun DI, Loew C

2018

doi:10.1016/j.str.2018.07.016.

Recombinant production of A1S_0222 from acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity.

Blaschke U, Suwono B, Zafari S, Ebersberger I, Skiebe E, Jeffries CM, Svergun DI, Wilharm G

Protein expression and purification 2018

doi:10.1016/j.pep.2018.06.009.

Formation of a Secretion-Competent Protein Complex by a Dynamic Wrap-around Binding Mechanism.

Gupta AA, Reinartz I, Karunanithy G, Spilotros A, Jonna VR, Hofer A, Svergun DI, Baldwin AJ, Schug A, Wolf-Watz M

Journal of molecular biology 2018

doi:10.1016/j.jmb.2018.07.014.

Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water".

Fuertes G, Banterle N, Ruff KM, Chowdhury A, Pappu RV, Svergun DI, Lemke EA

Science (New York, N.Y.) 2018

doi:10.1126/science.aau8230.

Conformational states of ABC transporter MsbA in a lipid environment investigated by small-angle scattering using stealth carrier nanodiscs.

Josts I, Nitsche J, Maric S, Mertens HD, Moulin M, Haertlein M, Prevost S, Svergun DI, Busch S, Forsyth VT, Tidow H

Structure (London, England : 1993) 2018

doi:10.1016/j.str.2018.05.007.

Structural complexity of the co-chaperone SGTA: a conserved C-terminal region is implicated in dimerization and substrate quality control.

Martínez-Lumbreras S, Krysztofinska EM, Thapaliya A, Spilotros A, Matak-Vinkovic D, Salvadori E, Roboti P, Nyathi Y, Muench JH, Roessler MM, Svergun DI, High S, Isaacson RL

BMC biology 2018

doi:10.1186/s12915-018-0542-3.

Small-Angle X-ray Scattering Study of Macrophage Migration Inhibitory Factor Complexed with Albumin

Petoukhov MV, Sokolov AV, Dadinova LA, Gorbunov NP, Svergun DI, Samygina VR

CRYSTALLOGRAPHY REPORTS 2018

doi:10.1134/S106377451804020X.

Smaller capillaries improve the small-angle X-ray scattering signal and sample consumption for biomacromolecular solutions.

Schroer MA, Blanchet CE, Gruzinov AY, Gräwert MA, Brennich ME, Hajizadeh NR, Jeffries CM, Svergun DI

2018

doi:10.1107/S1600577518007907.

iNEXT: a European facility network to stimulate translational structural biology.

iNEXT Consortium

FEBS letters 2018

doi:10.1002/1873-3468.13062.

Machine Learning Methods for X-Ray Scattering Data Analysis from Biomacromolecular Solutions.

Franke D, Jeffries CM, Svergun DI

Biophysical journal 2018

doi:10.1016/j.bpj.2018.04.018.

CHROMIXS: automatic and interactive analysis of chromatography-coupled small angle X-ray scattering data.

Panjkovich A, Svergun DI

Bioinformatics (Oxford, England) 2017

doi:10.1093/bioinformatics/btx846.

Direct shape determination of intermediates in evolving macromolecular solutions from small-angle scattering data.

Konarev PV, Svergun DI

IUCrJ 2018

doi:10.1107/S2052252518005900.

Optical and Structural Characterization of a Chronic Myeloid Leukemia DNA Biosensor.

Cordeiro M, Otrelo-Cardoso AR, Svergun DI, Konarev PV, Lima JC, Santos-Silva T, Baptista PV

ACS chemical biology 2018

doi:10.1021/acschembio.8b00029.

Structure specific recognition protein-1 (SSRP1) is an elongated homodimer that binds histones.

Marcianò G, Da Vela S, Tria G, Svergun DI, Byron O, Huang DT

The Journal of biological chemistry 2018

doi:10.1074/jbc.RA117.000994.

Consensus bayesian assessment of protein molecular mass from solution X-ray scattering data.

Hajizadeh NR, Franke D, Jeffries CM, Svergun DI.

2018

doi:10.1038/s41598-018-25355-2.

Integrated beamline control and data acquisition for small-angle X-ray scattering at the P12 BioSAXS beamline at PETRAIII storage ring DESY.

Hajizadeh NR, Franke D, Svergun DI

Journal of synchrotron radiation 2018

doi:10.1107/S1600577518005398.

Functional interaction of low-homology FRPs from different cyanobacteria with Synechocystis OCP

Slonimskiy YB, Maksimov EG, Lukashev EP, Moldenhauer M, Jeffries CM, Svergun DI, Friedrich T, Sluchanko NN.

2018

doi:10.1016/j.bbabio.2018.03.001.

A general small-angle X-ray scattering-based screening protocol validated for protein-RNA interactions.

Chen PC, Masiewicz P, Rybin V, Svergun D, Hennig J

ACS combinatorial science 2018

doi:10.1021/acscombsci.8b00007.

Quantitative 3D determination of self-assembled structures on nanoparticles using small angle neutron scattering.

Luo Z, Marson D, Ong QK, Loiudice A, Kohlbrecher J, Radulescu A, Krause-Heuer A, Darwish T, Balog S, Buonsanti R, Svergun DI, Posocco P, Stellacci F

Nature communications 2018

doi:10.1038/s41467-018-03699-7.

Recent developments in small-angle X-ray scattering and hybrid method approaches for biomacromolecular solutions

Schroer MA, Svergun DI

2018

doi:10.1042/ETLS20170138.

Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.

Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R

Neuron 2018

doi:10.1016/j.neuron.2018.02.010.

Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.

de Moura TR, Mozaffari-Jovin S, Szabó CZK, Schmitzová J, Dybkov O, Cretu C, Kachala M, Svergun D, Urlaub H, Lührmann R, Pena V

Molecular cell 2018

doi:10.1016/j.molcel.2018.02.022.

Structural model of human dUTPase in complex with a novel proteinaceous inhibitor.

Nyíri K, Mertens HDT, Tihanyi B, Nagy GN, Kőhegyi B, Matejka J, Harris MJ, Szabó JE, Papp-Kádár V, Németh-Pongrácz V, Ozohanics O, Vékey K, Svergun DI, Borysik AJ, Vértessy BG

Scientific reports 2018

doi:10.1038/s41598-018-22145-8.

Disease Variants of FGFR3 Reveal Molecular Basis for the Recognition and Additional Roles for Cdc37 in Hsp90 Chaperone System.

Bunney TD, Inglis AJ, Sanfelice D, Farrell B, Kerr CJ, Thompson GS, Masson GR, Thiyagarajan N, Svergun DI, Williams RL, Breeze AL, Katan M

Structure (London, England : 1993) 2018

doi:10.1016/j.str.2018.01.016.

Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.

Falke S, Dierks K, Blanchet C, Graewert M, Cipriani F, Meijers R, Svergun D, Betzel C

Journal of synchrotron radiation 2018

doi:10.1107/S1600577517017568.

Matrix proteins of enveloped viruses: a case study of Influenza A virus M1 protein.

Kordyukova LV, Shtykova EV, Baratova LA, Svergun DI, Batishchev OV

Journal of biomolecular structure & dynamics 2018

doi:10.1080/07391102.2018.1436089.

Macromolecular pHPMA-Based Nanoparticles with Cholesterol for Solid Tumor Targeting: Behavior in HSA Protein Environment.

Zhang X, Niebuur BJ, Chytil P, Etrych T, Filippov SK, Kikhney A, Wieland DCF, Svergun DI, Papadakis CM

Biomacromolecules 2018

doi:10.1021/acs.biomac.7b01579.

Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research.

Flayhan A, Mertens HDT, Ural-Blimke Y, Martinez Molledo M, Svergun DI, Löw C

Structure (London, England : 1993) 2018

doi:10.1016/j.str.2018.01.007.

The Molecular Bases of the Dual Regulation of Bacterial Iron Sulfur Cluster Biogenesis by CyaY and IscX.

Adinolfi S, Puglisi R, Crack JC, Iannuzzi C, Dal Piaz F, Konarev PV, Svergun DI, Martin S, Le Brun NE, Pastore A

Frontiers in molecular biosciences 2017

doi:10.3389/fmolb.2017.00097.

Structural insights of RmXyn10A - A prebiotic-producing GH10 xylanase with a non-conserved aglycone binding region.

Aronsson A, Güler F, Petoukhov MV, Crennell SJ, Svergun DI, Linares-Pastén JA, Karlsson EN

Biochimica et biophysica acta 2017

doi:10.1016/j.bbapap.2017.11.006.

Epsin and Sla2 form assemblies through phospholipid interfaces.

Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R

Nature communications 2018

doi:10.1038/s41467-017-02443-x.

Signaling ammonium across membranes through an ammonium sensor histidine kinase.

Pflüger T, Hernández CF, Lewe P, Frank F, Mertens H, Svergun D, Baumstark MW, Lunin VY, Jetten MSM, Andrade SLA

Nature communications 2018

doi:10.1038/s41467-017-02637-3.

Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.

Reckel S, Gehin C, Tardivon D, Georgeon S, Kükenshöner T, Löhr F, Koide A, Buchner L, Panjkovich A, Reynaud A, Pinho S, Gerig B, Svergun D, Pojer F, Güntert P, Dötsch V, Koide S, Gavin AC, Hantschel O

Nature communications 2017

doi:10.1038/s41467-017-02313-6.

Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics.

Shtykova EV, Dadinova LA, Fedorova NV, Golanikov AE, Bogacheva EN, Ksenofontov AL, Baratova LA, Shilova LA, Tashkin VY, Galimzyanov TR, Jeffries CM, Svergun DI, Batishchev OV

Scientific reports 2017

doi:10.1038/s41598-017-16986-y.

Structuralization of magnetic nanoparticles in 5CB liquid crystals.

Gdovinová V, Schroer MA, Tomašovičová N, Appel I, Behrens S, Majorošová J, Kováč J, Svergun DI, Kopčanský P

Soft matter 2017

doi:10.1039/c7sm01234a.

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.

Trewhella J, Duff AP, Durand D, Gabel F, Guss JM, Hendrickson WA, Hura GL, Jacques DA, Kirby NM, Kwan AH, Pérez J, Pollack L, Ryan TM, Sali A, Schneidman-Duhovny D, Schwede T, Svergun DI, Sugiyama M, Tainer JA, Vachette P, Westbrook J, Whitten AE

Acta crystallographica. Section D, Structural biology 2017

doi:10.1107/S2059798317011597.

Block and Gradient Copoly(2-oxazoline) Micelles: Strikingly Different on the Inside.

Filippov SK, Verbraeken B, Konarev PV, Svergun DI, Angelov B, Vishnevetskaya NS, Papadakis CM, Rogers S, Radulescu A, Courtin T, Martins JC, Starovoytova L, Hruby M, Stepanek P, Kravchenko VS, Potemkin II, Hoogenboom R

The journal of physical chemistry letters 2017

doi:10.1021/acs.jpclett.7b01588.

Combining NMR and small angle X-ray scattering for the study of biomolecular structure and dynamics.

Mertens HDT, Svergun DI

Archives of biochemistry and biophysics 2017

doi:10.1016/j.abb.2017.05.005.

Progress in small-angle scattering from biological solutions at high-brilliance synchrotrons.

Tuukkanen AT, Spilotros A, Svergun DI

IUCrJ 2017

doi:10.1107/S2052252517008740.

Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements.

Fuertes G, Banterle N, Ruff KM, Chowdhury A, Mercadante D, Koehler C, Kachala M, Estrada Girona G, Milles S, Mishra A, Onck PR, Gräter F, Esteban-Martín S, Pappu RV, Svergun DI, Lemke EA

Proceedings of the National Academy of Sciences of the United States of America 2017

doi:10.1073/pnas.1704692114.

Highly selective tungstate transporter protein TupA from Desulfovibrio alaskensis G20.

Otrelo-Cardoso AR, Nair RR, Correia MAS, Cordeiro RSC, Panjkovich A, Svergun DI, Santos-Silva T, Rivas MG

Scientific reports 2017

doi:10.1038/s41598-017-06133-y.

A Spring-Loaded Mechanism Governs the Clamp-like Dynamics of the Skp Chaperone.

Holdbrook DA, Burmann BM, Huber RG, Petoukhov MV, Svergun DI, Hiller S, Bond PJ

Structure (London, England : 1993) 2017

doi:10.1016/j.str.2017.05.018.

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

Franke D, Petoukhov MV, Konarev PV, Panjkovich A, Tuukkanen A, Mertens HDT, Kikhney AG, Hajizadeh NR, Franklin JM, Jeffries CM, Svergun DI

2017

doi:10.1107/S1600576717007786.

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Beckham KS, Ciccarelli L, Bunduc CM, Mertens HD, Ummels R, Lugmayr W, Mayr J, Rettel M, Savitski MM, Svergun DI, Bitter W, Wilmanns M, Marlovits TC, Parret AH, Houben EN

Nature microbiology 2017

doi:10.1038/nmicrobiol.2017.47.

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes.

Sundaramoorthy R, Hughes AL, Singh V, Wiechens N, Ryan DP, El-Mkami H, Petoukhov M, Svergun DI, Treutlein B, Quack S, Fischer M, Michaelis J, Böttcher B, Norman DG, Owen-Hughes T

eLife 2017

doi:10.7554/elife.22510.

Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.

Sviridova E, Rezacova P, Bondar A, Veverka V, Novak P, Schenk G, Svergun DI, Kuta Smatanova I, Bumba L

Scientific reports 2017

doi:10.1038/srep40408.

The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain.

Mauricio RP, Jeffries CM, Svergun DI, Deane JE

The Journal of biological chemistry 2016

doi:10.1074/jbc.m116.758003.

Validation of biological small-angle scattering data and models in SASBDB.

Kikhney A, Jeffries CM, Borges CR, Hajizadeh N, Manalastas KK, Svergun DI

2017

doi:https://doi.org/10.1107/s2053273317081360.

Analysis of self-assembly of S-layer protein slp-B53 from Lysinibacillus sphaericus.

Liu J, Falke S, Drobot B, Oberthuer D, Kikhney A, Guenther T, Fahmy K, Svergun D, Betzel C, Raff J

European biophysics journal : EBJ 2016

doi:10.1007/s00249-016-1139-9.

Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners.

Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov MV, Spilotros A, Svergun DI, Di Gaetano S, Vitagliano L, Pedone EM

Biochimie 2016

doi:10.1016/j.biochi.2016.09.013.

Potent and selective bivalent inhibitors of BET bromodomains

Waring M., Chen H., Rabow A., Walker G., Bobby R., Boiko S., Bradbury R., Callis R., Clark E., Dale I., Daniels D., Dulak A., Flavell L., Holdgate G., Jowitt T., Kikhney A., McAlister M., Méndez J., Ogg D., Patel J., Petteruti P., Robb G., Robers M., Saif S., Stratton N., Svergun D., Wang W., Whittaker D., Wilson D., Yao Y.

Nature Chemical Biology 2016

doi:10.1038/nchembio.2210.

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.

Jeffries CM, Graewert MA, Blanchet CE, Langley DB, Whitten AE, Svergun DI

Nature protocols 2016

doi:10.1038/nprot.2016.113.

Resolution of ab initio shapes determined from small-angle scattering

Tuukkanen A., Kleywegt G., Svergun D.

IUCrJ 2016

doi:10.1107/S2052252516016018.

Virus Matryoshka: A Bacteriophage Particle-Guided Molecular Assembly Approach to a Monodisperse Model of the Immature Human Immunodeficiency Virus.

Saxena P, He L, Malyutin A, Datta SA, Rein A, Bond KM, Jarrold MF, Spilotros A, Svergun D, Douglas T, Dragnea B

Small (Weinheim an der Bergstrasse, Germany) 2016

doi:10.1002/smll.201601712.

Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation.

Buetow L, Tria G, Ahmed SF, Hock A, Dou H, Sibbet GJ, Svergun DI, Huang DT

BMC biology 2016

doi:10.1186/s12915-016-0298-6.

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.

Schulte T, Mikaelsson C, Beaussart A, Kikhney A, Deshmukh M, Wolniak S, Pathak A, Ebel C, Löfling J, Fogolari F, Henriques-Normark B, Dufrêne YF, Svergun D, Nygren PÅ, Achour A

Scientific reports 2016

doi:10.1038/srep32371.

The flexibility of a homeodomain transcription factor heterodimer and its allosteric regulation by DNA binding.

Mathiasen L, Valentini E, Boivin S, Cattaneo A, Blasi F, Svergun DI, Bruckmann C

The FEBS journal 2016

doi:10.1111/febs.13801.

Structure and target interaction of a G-quadruplex RNA-aptamer.

Szameit K, Berg K, Kruspe S, Valentini E, Magbanua E, Kwiatkowski M, Chauvot de Beauchêne I, Krichel B, Schamoni K, Uetrecht C, Svergun DI, Schlüter H, Zacharias M, Hahn U

RNA biology 2016

doi:10.1080/15476286.2016.1212151.

Anisotropic lanthanide-based nano-clusters for imaging applications.

Yang X, Wang S, King TL, Kerr CJ, Blanchet C, Svergun D, Pal R, Beeby A, Vadivelu J, Brown KA, Jones RA, Zhang L, Huang S

Faraday discussions 2016

doi:10.1039/c6fd00018e.

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases.

Valencia-Sánchez MI, Rodríguez-Hernández A, Ferreira R, Santamaría-Suárez HA, Arciniega M, Dock-Bregeon AC, Moras D, Beinsteiner B, Mertens H, Svergun D, Brieba LG, Grøtli M, Torres-Larios A

The Journal of biological chemistry 2016

doi:10.1074/jbc.m116.730382.

SASpy: a PyMOL plugin for manipulation and refinement of hybrid models against small angle X-ray scattering data.

Panjkovich A, Svergun DI

Bioinformatics (Oxford, England) 2016

doi:10.1093/bioinformatics/btw071.

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs.

Plath F, Ringler P, Graff-Meyer A, Stahlberg H, Lauer ME, Rufer AC, Graewert MA, Svergun D, Gellermann G, Finkler C, Stracke JO, Koulov A, Schnaible V

mAbs 2016

doi:10.1080/19420862.2016.1168960.

Immunosuppressive Yersinia Effector YopM Binds DEAD Box Helicase DDX3 to Control Ribosomal S6 Kinase in the Nucleus of Host Cells.

Berneking L, Schnapp M, Rumm A, Trasak C, Ruckdeschel K, Alawi M, Grundhoff A, Kikhney AG, Koch-Nolte F, Buck F, Perbandt M, Betzel C, Svergun DI, Hentschke M, Aepfelbacher M

PLoS pathogens 2016

doi:10.1371/journal.ppat.1005660.

Death-Associated Protein Kinase Activity Is Regulated by Coupled Calcium/Calmodulin Binding to Two Distinct Sites

Simon B, Huart A, Temmerman K, Vahokoski J, Mertens H, Komadina D, Hoffmann J, Yumerefendi H, Svergun D, Kursula P, Schultz C, McCarthy A, Hart D, Wilmanns M

Structure 2016

doi:10.1016/j.str.2016.03.020.

X-Ray Solution Scattering Study of Four Escherichia coli Enzymes Involved in Stationary-Phase Metabolism

Dadinova LA, Shtykova EV, Konarev PV, Rodina EV, Snalina NE, Vorobyeva NN, Kurilova SA, Nazarova TI, Jeffries CM, Svergun DI.

2016

doi:10.1371/journal.pone.0156105.

Rapid automated superposition of shapes and macromolecular models using spherical harmonics.

Konarev PV, Petoukhov MV, Svergun DI

Journal of applied crystallography 2016

doi:10.1107/S1600576716005793.

Calcium-Driven Folding of RTX Domain β-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.

Bumba L, Masin J, Macek P, Wald T, Motlova L, Bibova I, Klimova N, Bednarova L, Veverka V, Kachala M, Svergun DI, Barinka C, Sebo P

Molecular cell 2016

doi:10.1016/j.molcel.2016.03.018.

LabDisk for SAXS: a centrifugal microfluidic sample preparation platform for small-angle X-ray scattering.

Schwemmer F, Blanchet CE, Spilotros A, Kosse D, Zehnle S, Mertens HD, Graewert MA, Rössle M, Paust N, Svergun DI, von Stetten F, Zengerle R, Mark D

Lab on a chip 2016

doi:10.1039/c5lc01580d.

Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.

Drebes J, Künz M, Windshügel B, Kikhney AG, Müller IB, Eberle RJ, Oberthür D, Cang H, Svergun DI, Perbandt M, Betzel C, Wrenger C

Scientific reports 2016

doi:10.1038/srep22871.

Crystal structure of the CTP1L endolysin reveals how its activity is regulated by a secondary translation product.

Dunne M, Leicht S, Krichel B, Mertens HD, Thompson A, Krijgsveld J, Svergun DI, Gómez-Torres N, Garde S, Uetrecht C, Narbad A, Mayer MJ, Meijers R

The Journal of biological chemistry 2015

doi:10.1074/jbc.M115.671172.

Solution Behavior of the Intrinsically Disordered N-Terminal Domain of Retinoid X Receptor α in the Context of the Full-Length Protein.

Belorusova AY, Osz J, Petoukhov MV, Peluso-Iltis C, Kieffer B, Svergun DI, Rochel N

Biochemistry 2016

doi:10.1021/acs.biochem.5b01122.

Deciphering conformational transitions of proteins by small angle X-ray scattering and normal mode analysis.

Panjkovich A, Svergun DI

Physical chemistry chemical physics : PCCP 2015

doi:10.1039/c5cp04540a.

Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158.

Boer DR, Ruiz-Masó JA, Rueda M, Petoukhov MV, Machón C, Svergun DI, Orozco M, Del Solar G, Coll M

Scientific reports 2016

doi:10.1038/srep20915.

Extension of the sasCIF format and its applications for data processing and deposition.

Kachala M, Westbrook J, Svergun D

Journal of applied crystallography 2016

doi:10.1107/S1600576715024942.

DARA: a web server for rapid search of structural neighbours using solution small angle X-ray scattering data.

Kikhney AG, Panjkovich A, Sokolova AV, Svergun DI

Bioinformatics (Oxford, England) 2015

doi:10.1093/bioinformatics/btv611.

Dual Role of the Active Site Residues of Thermus thermophilus 3-Isopropylmalate Dehydrogenase: Chemical Catalysis and Domain Closure.

Gráczer É, Szimler T, Garamszegi A, Konarev PV, Lábas A, Oláh J, Palló A, Svergun DI, Merli A, Závodszky P, Weiss MS, Vas M

Biochemistry 2016

doi:10.1021/acs.biochem.5b00839.

The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.

Albesa-Jové D, Comino N, Tersa M, Mohorko E, Urresti S, Dainese E, Chiarelli LR, Pasca MR, Manganelli R, Makarov V, Riccardi G, Svergun DI, Glockshuber R, Guerin ME

The Journal of biological chemistry 2015

doi:10.1074/jbc.M115.677039.

KSHV but not MHV-68 LANA induces a strong bend upon binding to terminal repeat viral DNA.

Ponnusamy R, Petoukhov MV, Correia B, Custodio TF, Juillard F, Tan M, Pires de Miranda M, Carrondo MA, Simas JP, Kaye KM, Svergun DI, McVey CE.

Nucleic acids research 2015

doi:10.1093/nar/gkv987.

Application of SAXS for the Structural Characterization of IDPs.

Kachala M, Valentini E, Svergun DI

Advances in experimental medicine and biology 2015

doi:10.1007/978-3-319-20164-1_8.

Maturation of 6S regulatory RNA to a highly elongated structure.

Fadouloglou VE, Lin HV, Tria G, Hernández H, Robinson CV, Svergun DI, Luisi BF

The FEBS journal 2015

doi:10.1111/febs.13516.

A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins.

Kikhney AG, Svergun DI

FEBS letters 2015

doi:10.1016/j.febslet.2015.08.027.

RAID3 - An interleukin-6 receptor-binding aptamer with post-selective modification-resistant affinity.

Mittelberger F, Meyer C, Waetzig GH, Zacharias M, Valentini E, Svergun DI, Berg K, Lorenzen I, Grötzinger J, Rose-John S, Hahn U

RNA biology 2015

doi:10.1080/15476286.2015.1079681.

Molecular mechanism for the action of the anti-CD44 monoclonal antibody MEM-85.

Škerlová J, Král V, Kachala M, Fábry M, Bumba L, Svergun DI, Tošner Z, Veverka V, Řezáčová P

Journal of structural biology 2015

doi:10.1016/j.jsb.2015.06.005.

Structural basis for antigen recognition by transglutaminase 2-specific autoantibodies in celiac disease.

Chen X, Hnida K, Graewert MA, Andersen JT, Iversen R, Tuukkanen A, Svergun D, Sollid LM

The Journal of biological chemistry 2015

doi:10.1074/jbc.M115.669895.

Kirkwood-Buff Approach Rescues Overcollapse of a Disordered Protein in Canonical Protein Force Fields

Mercadante D, Milles S, Fuertes G, Svergun DI, Lemke EA, Gräter F

JOURNAL OF PHYSICAL CHEMISTRY B 2015

doi:10.1021/acs.jpcb.5b03440.

Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop.

Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD

Structure (London, England : 1993) 2015

doi:10.1016/j.str.2015.05.013.

Coat Protein-Dependent Behavior of Poly(ethylene glycol) Tails in Iron Oxide Core Virus-like Nanoparticles

Malyutin AG, Cheng H, Sanchez-Felix OR, Carlson K, Stein BD, Konarev PV, Svergun DI, Dragnea B, Bronstein LM

ACS Applied Materials and Interfaces 2015

doi:10.1021/acsami.5b02278.

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI

Scientific reports 2015

doi:10.1038/srep10734.

Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein.

Gruszka DT, Whelan F, Farrance OE, Fung HK, Paci E, Jeffries CM, Svergun DI, Baldock C, Baumann CG, Brockwell DJ, Potts JR, Clarke J

Nature communications 2015

doi:10.1038/ncomms8271.

Ambiguity assessment of small-angle scattering curves from monodisperse systems.

Petoukhov MV, Svergun DI

Acta crystallographica. Section D, Biological crystallography 2015

doi:10.1107/s1399004715002576.

pyDockSAXS: protein-protein complex structure by SAXS and computational docking.

Jiménez-García B, Pons C, Svergun DI, Bernadó P, Fernández-Recio J

Nucleic acids research 2015

doi:10.1093/nar/gkv368.

A posteriori determination of the useful data range for small-angle scattering experiments on dilute monodisperse systems.

Konarev PV, Svergun DI

IUCrJ 2015

doi:10.1107/s2052252515005163.

Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra.

Franke D, Jeffries CM, Svergun DI

2015

doi:10.1038/nmeth.3358.

The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

Langkilde AE, Morris KL, Serpell LC, Svergun DI, Vestergaard B

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 2015

doi:10.1107/S1399004715001674.

Structure and catalytic mechanism of the evolutionarily unique bacterial chalcone isomerase

Thomsen M, Tuukkanen A, Dickerhoff J, Palm GJ, Kratzat H, Svergun DI, Weisz K, Bornscheuer UT, Hinrichs W

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 2015

doi:10.1107/S1399004715001935.

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY).

Blanchet CE, Spilotros A, Schwemmer F, Graewert MA, Kikhney A, Jeffries CM, Franke D, Mark D, Zengerle R, Cipriani F, Fiedler S, Roessle M, Svergun DI

Journal of applied crystallography 2015

doi:10.1107/s160057671500254x.

Structural Insights into Ca(2+)-Calmodulin Regulation of Plectin 1a-Integrin β4 Interaction in Hemidesmosomes.

Song JG, Kostan J, Drepper F, Knapp B, de Almeida Ribeiro E Jr, Konarev PV, Grishkovskaya I, Wiche G, Gregor M, Svergun DI, Warscheid B, Djinović-Carugo K

Structure (London, England : 1993) 2015

doi:10.1016/j.str.2015.01.011.

A small and robust active beamstop for scattering experiments on high-brilliance undulator beamlines.

Blanchet CE, Hermes C, Svergun DI, Fiedler S

Journal of synchrotron radiation 2015

doi:10.1107/s160057751402829x.

Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering.

Tria G, Mertens HD, Kachala M, Svergun DI

IUCrJ 2015

doi:10.1107/s205225251500202x.

Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII

Jeffries CM, Graewert MA, Svergun DI, Blanchet CE

2015

doi:10.1107/S1600577515000375.

The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?

Covaceuszach S, Konarev PV, Cassetta A, Paoletti F, Svergun DI, Lamba D, Cattaneo A

Biophysical journal 2015

doi:10.1016/j.bpj.2014.11.3485.

SASBDB, a repository for biological small-angle scattering data

Valentini E, Kikhney AG, Previtali G, Jeffries CM, Svergun DI

Nucleic acids research 2014

doi:10.1093/nar/gku1047.

Glutamate 270 plays an essential role in K(+)-activation and domain closure of Thermus thermophilus isopropylmalate dehydrogenase.

Gráczer É, Palló A, Oláh J, Szimler T, Konarev PV, Svergun DI, Merli A, Závodszky P, Weiss MS, Vas M

FEBS letters 2015

doi:10.1016/j.febslet.2014.12.005.

Viruslike Nano Particles with Maghemite Cores Allow for Enhanced MRI Contrast Agents

Malyutin AG, Easterday R, Lozovyy Y, Spilotros A, Cheng H, Sanchez-Felix OR, Stein BD, Morgan DG, Svergun DI, Dragnea B, Bronstein LM

CHEMISTRY OF MATERIALS 2015

doi:10.1021/cm504029j.

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC.

Tallant C, Valentini E, Fedorov O, Overvoorde L, Ferguson FM, Filippakopoulos P, Svergun DI, Knapp S, Ciulli A

Structure (London, England : 1993) 2015

doi:10.1016/j.str.2014.10.017.

ISPyB for BioSAXS, the gateway to user autonomy in solution scattering experiments.

De Maria Antolinos A, Pernot P, Brennich ME, Kieffer J, Bowler MW, Delageniere S, Ohlsson S, Malbet Monaco S, Ashton A, Franke D, Svergun D, McSweeney S, Gordon E, Round A

Acta crystallographica. Section D, Biological crystallography 2015

doi:10.1107/s1399004714019609.

A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide.

Hagelueken G, Clarke BR, Huang H, Tuukkanen A, Danciu I, Svergun DI, Hussain R, Liu H, Whitfield C, Naismith JH

Nature structural & molecular biology 2014

doi:10.1038/nsmb.2935.

High-throughput studies of protein shapes and interactions by synchrotron small-angle x-ray scattering.

Jeffries CM, Svergun DI

Methods in molecular biology (Clifton, N.J.) 2015

doi:10.1007/978-1-4939-2230-7_15.

BioSAXS Sample Changer: a robotic sample changer for rapid and reliable high-throughput X-ray solution scattering experiments.

Round A, Felisaz F, Fodinger L, Gobbo A, Huet J, Villard C, Blanchet CE, Pernot P, McSweeney S, Roessle M, Svergun DI, Cipriani F

2015

doi:10.1107/S1399004714026959.

The Structure and Regulation of Human Muscle α-Actinin.

Ribeiro ED Jr, Pinotsis N, Ghisleni A, Salmazo A, Konarev PV, Kostan J, Sjöblom B, Schreiner C, Polyansky AA, Gkougkoulia EA, Holt MR, Aachmann FL, Zagrović B, Bordignon E, Pirker KF, Svergun DI, Gautel M, Djinović-Carugo K

Cell 2014

doi:10.1016/j.cell.2014.10.056.

The SH2 domain of Abl kinases regulates kinase autophosphorylation by controlling activation loop accessibility.

Lamontanara AJ, Georgeon S, Tria G, Svergun DI, Hantschel O

Nature communications 2014

doi:10.1038/ncomms6470.

Structural Basis of a Kv7.1 Potassium Channel Gating Module: Studies of the Intracellular C-Terminal Domain in Complex with Calmodulin.

Sachyani D, Dvir M, Strulovich R, Tria G, Tobelaim W, Peretz A, Pongs O, Svergun D, Attali B, Hirsch JA

Structure (London, England : 1993) 2014

doi:10.1016/j.str.2014.07.016.

Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, van den Elsen JM, Danson MJ

The Biochemical journal 2014

doi:10.1042/bj20140359.

Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients.

Nilsson OB, Neimert-Andersson T, Bronge M, Grundström J, Sarma R, Uchtenhagen H, Kikhney A, Sandalova T, Holmgren E, Svergun D, Achour A, van Hage M, Grönlund H

PloS one 2014

doi:10.1371/journal.pone.0111041.

Endophilin-A1 BAR domain interaction with arachidonyl CoA.

Petoukhov MV, Weissenhorn W, Svergun DI

2014

doi:10.3389/fmolb.2014.00020.

Correction to ‘The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold’.

Schulte T, Löfling J, Mikaelsson C, Kikhney A, Hentrich K, Diamante A, Ebel C, Normark S, Svergun D, Henriques-Normark B, Achour A

Open biology 2014

doi:10.1098/rsob.140172.

Hydrophobic Periphery Tails of Polyphenylenepyridyl Dendrons Control Nanoparticle Formation and Catalytic Properties

Kuchkina NV, Morgan DG, Kostopoulou A, Lappas A, Brintakis K, Boris BS, Yuzik-Klimova EY, Stein BD, Svergun DI, Spilotros A, Sulman MG, Nikoshvili LZ, Sulman EM, Shifrina ZB, Bronstein LM

CHEMISTRY OF MATERIALS 2014

doi:10.1021/cm502336n.

The Crystal Structure of Netrin-1 in Complex with DCC Reveals the Bifunctionality of Netrin-1 As a Guidance Cue

Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R

Neuron 2014

doi:10.1016/j.neuron.2014.07.010.

Structure of the C. elegans ZYG-1 Cryptic Polo Box Suggests a Conserved Mechanism for Centriolar Docking of Plk4 Kinases

Shimanovskaya E, Viscardi V, Lesigang J, Lettman MM, Qiao R, Svergun DI, Round A, Oegema K, Dong G

Structure (London, England : 1993) 2014

doi:10.1016/j.str.2014.05.009.

Novel thermosensitive telechelic PEGs with antioxidant activity: synthesis, molecular properties and conformational behaviour

Sergeeva O, Vlasov PS, Domnina NS, Bogomolova A, Konarev PV, Svergun DI, Walterova Z, Horsky J, Stepanek P, Filippov SK

RSC ADVANCES 2014

doi:10.1039/c4ra06978a.

A conformational switch in collybistin determines the differentiation of inhibitory postsynapses

Soykan T, Schneeberger D, Tria G, Buechner C, Bader N, Svergun D, Tessmer I, Poulopoulos A, Papadopoulos T, Varoqueaux F, Schindelin H, Brose N

The EMBO journal 2014

doi:10.15252/embj.201488143.

The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R

PLoS pathogens 2014

doi:10.1371/journal.ppat.1004228.

Multicore Iron Oxide Mesocrystals Stabilized by Polyphe-nylenepyridyl Dendron and Dendrimer: Role of the Den-dron/Dendrimer Self-assembly

Morgan DG, Boris BS, Kuchkina NV, Yuzik-Klimova EY, Sorokina S, Stein BD, Svergun DI, Spilotros A, Kostopoulou A, Lappas A, Shifrina ZB, Bronstein LM

Langmuir : the ACS journal of surfaces and colloids 2014

doi:10.1021/la502409r.

Interactions of ataxin-3 with its molecular partners in the protein machinery that sorts protein aggregates to the aggresome.

Bonanomi M, Mazzucchelli S, D'Urzo A, Nardini M, Konarev PV, Invernizzi G, Svergun DI, Vanoni M, Regonesi ME, Tortora P

The international journal of biochemistry & cell biology 2014

doi:10.1016/j.biocel.2014.03.015.

The C-terminal random coil region tunes the Ca²⁺-binding affinity of S100A4 through conformational activation

Duelli A, Kiss B, Lundholm I, Bodor A, Petoukhov MV, Svergun DI, Nyitray L, Katona G

PloS one 2014

doi:10.1371/journal.pone.0097654.

The histone chaperones Vps75 and Nap1 form ring-like, tetrameric structures in solution

Bowman A, Hammond CM, Stirling A, Ward R, Shang W, El-Mkami H, Robinson DA, Svergun DI, Norman DG, Owen-Hughes T

Nucleic acids research 2014

doi:10.1093/nar/gku232.

Structural Insight into How Streptomyces coelicolor Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme Intermediate

Syson K, Stevenson CE, Rashid AM, Saalbach G, Tang M, Tuukkanen A, Svergun DI, Withers SG, Lawson DM, Bornemann S

Biochemistry 2014

doi:10.1021/bi500183c.

Flexibility of the Linker between the Domains of DNA Methyltransferase SsoII Revealed by Small-Angle X-Ray Scattering: Implications for Transcription Regulation in SsoII Restriction-Modification System

Konarev PV, Kachalova GS, Ryazanova AY, Kubareva EA, Karyagina AS, Bartunik HD, Svergun DI

PloS one 2014

doi:10.1371/journal.pone.0093453.

Weak protein-ligand interactions studied by small-angle X-ray scattering.

Tuukkanen AT, Svergun DI

The FEBS journal 2014

doi:10.1111/febs.12772.

Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution

Malecki PH, Vorgias CE, Petoukhov MV, Svergun DI, Rypniewski W

Acta crystallographica. Section D, Biological crystallography 2014

doi:10.1107/s1399004713032264.

Scanning tunneling microscopy and small angle neutron scattering study of mixed monolayer protected gold nanoparticles in organic solvents

Moglianetti M, Ong QK, Reguera J, Harkness KM, Mameli M, Radulescu A, Kohlbrecher J, Jud C, Svergun DI, Stellacci F

CHEMICAL SCIENCE 2013

doi:10.1039/c3sc52595c.

Structural and Functional Insights into Peptidoglycan Access for the Lytic Amidase LytA of Streptococcus pneumoniae

Mellroth P, Sandalova T, Kikhney A, Vilaplana F, Hesek D, Lee M, Mobashery S, Normark S, Svergun D, Henriques-Normark B, Achour A

MBIO 2014

doi:10.1128/mBio.01120-13.

Inhibition of master transcription factors in pluripotent cells induces early stage differentiation

De D, Jeong MH, Leem YE, Svergun DI, Wemmer DE, Kang JS, Kim KK, Kim SH

Proceedings of the National Academy of Sciences of the United States of America 2014

doi:10.1073/pnas.1323386111.

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold

Schulte T, Lofling J, Mikaelsson C, Kikhney A, Hentrich K, Diamante A, Ebel C, Normark S, Svergun D, Henriques-Normark B, Achour A

OPEN BIOLOGY 2014

doi:10.1098/rsob.130090.

Exploring RNA oligomerization and ligand binding by fluorescence correlation spectroscopy and small angle X-ray scattering

Magbanua E, Konarev PV, Svergun DI, Hahn U

Methods in molecular biology (Clifton, N.J.) 2013

doi:10.1007/978-1-62703-667-2_19.

Structural data on the periplasmic aldehyde oxidoreductase PaoABC from Escherichia coli: SAXS and preliminary X-ray crystallography analysis

Otrelo-Cardoso AR, da Silva Correia MA, Schwuchow V, Svergun DI, Romão MJ, Leimkühler S, Santos-Silva T

International journal of molecular sciences 2014

doi:10.3390/ijms15022223.

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins

Varadi M, Kosol S, Lebrun P, Valentini E, Blackledge M, Dunker AK, Felli IC, Forman-Kay JD, Kriwacki RW, Pierattelli R, Sussman J, Svergun DI, Uversky VN, Vendruscolo M, Wishart D, Wright PE, Tompa P

Nucleic acids research 2013

doi:10.1093/nar/gkt960.

The 11th International Conference on Biology and Synchrotron Radiation

Wilmanns M, Svergun DI

Journal of synchrotron radiation 2014

doi:10.1107/s1600577513030609.

Solution study of novel diblock copolymers: Morphology and structural transition

Shtykova EV, Kabachii YA, Valetsky PM, Kochev SS, Malyutin AG, Stein BD, Bronstein LM, Svergun DI

POLYMER 2013

doi:10.1016/j.polymer.2013.10.047.

Staphylococcus aureus thiaminase II: oligomerization warrants proteolytic protection against serine proteases

Begum A, Drebes J, Kikhney A, Müller IB, Perbandt M, Svergun D, Wrenger C, Betzel C

Acta crystallographica. Section D, Biological crystallography 2013

doi:10.1107/s0907444913021550.

Hydrolytically degradable polymer micelles for drug delivery: a SAXS/SANS kinetic study

Filippov SK, Franklin JM, Konarev PV, Chytil P, Etrych T, Bogomolova A, Dyakonova M, Papadakis CM, Radulescu A, Ulbrich K, Stepanek P, Svergun DI

Biomacromolecules 2013

doi:10.1021/bm401186z.

Small Angle X-Ray and Neutron Scattering from Solutions of Biological Macromolecules

Svergun DI, Koch MHJ, Timmins PA, May RP

2013

doi:10.1093/acprof:oso/9780199639533.001.0001.

Examination of matrix metalloproteinase-1 in solution: a preference for the pre-collagenolysis state

Cerofolini L, Fields GB, Fragai M, Geraldes CF, Luchinat C, Parigi G, Ravera E, Svergun DI, Teixeira JM

The Journal of biological chemistry 2013

doi:10.1074/jbc.m113.477240.

Conformational plasticity of the essential membrane-associated mannosyltransferase PimA from mycobacteria

Giganti D, Alegre-Cebollada J, Urresti S, Albesa-Jové D, Rodrigo-Unzueta A, Comino N, Kachala M, López-Fernández S, Svergun DI, Fernández JM, Guerin ME

The Journal of biological chemistry 2013

doi:10.1074/jbc.m113.462705.

Impact and progress in small and wide angle X-ray scattering (SAXS and WAXS)

Graewert MA, Svergun DI

Current opinion in structural biology 2013

doi:10.1016/j.sbi.2013.06.007.

Reconstruction of quaternary structure from X-ray scattering by equilibrium mixtures of biological macromolecules

Petoukhov MV, Billas IM, Takacs M, Graewert MA, Moras D, Svergun DI

Biochemistry 2013

doi:10.1021/bi400731u.

Structural characterization of gephyrin by AFM and SAXS reveals a mixture of compact and extended states

Sander B, Tria G, Shkumatov AV, Kim EY, Grossmann JG, Tessmer I, Svergun DI, Schindelin H

Acta crystallographica. Section D, Biological crystallography 2013

doi:10.1107/s0907444913018714.

Flower-like iron oxide nanoparticles grown in polyphenylenepyridyl dendron/dendrimer solutions

Boris B, Prather F, Morgan DG, Kuchkina NV, Yuzik-Klimova EY, Sorokina SA, Svergun DI, Konarev PV, Spilotros A, Kostopoulou A, Lappas A, Shifrina ZB, Bronstein LM

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2013

doi:.

Gold coated iron oxide nanoparticles as cores for virus-like particles

Malyutin AG, Easterday R, Sanchez-Felix OR, Losovyj YB, Spilotros A, Svergun DI, Dragnea B, Bronstein LM

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2013

doi:.

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation

Groothuizen FS, Fish A, Petoukhov MV, Reumer A, Manelyte L, Winterwerp HH, Marinus MG, Lebbink JH, Svergun DI, Friedhoff P, Sixma TK

Nucleic acids research 2013

doi:10.1093/nar/gkt582.

A structural model of PpoA derived from SAXS-analysis-implications for substrate conversion

Koch C, Tria G, Fielding AJ, Brodhun F, Valerius O, Feussner K, Braus GH, Svergun DI, Bennati M, Feussner I

Biochimica et biophysica acta 2013

doi:10.1016/j.bbalip.2013.06.003.

Structural determinants and mechanism of mammalian CRM1 allostery

Dölker N, Blanchet CE, Voß B, Haselbach D, Kappel C, Monecke T, Svergun DI, Stark H, Ficner R, Zachariae U, Grubmüller H, Dickmanns A

Structure (London, England : 1993) 2013

doi:10.1016/j.str.2013.05.015.

Ferredoxin competes with bacterial frataxin in binding to the desulfurase IscS

Yan R, Konarev PV, Iannuzzi C, Adinolfi S, Roche B, Kelly G, Simon L, Martin SR, Py B, Barras F, Svergun DI, Pastore A

The Journal of biological chemistry 2013

doi:10.1074/jbc.m113.480327.

Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB

Trewhella J, Hendrickson WA, Kleywegt GJ, Sali A, Sato M, Schwede T, Svergun DI, Tainer JA, Westbrook J, Berman HM

Structure (London, England : 1993) 2013

doi:10.1016/j.str.2013.04.020.

Human IL-34 and CSF-1 establish structurally similar extracellular assemblies with their common hematopoietic receptor

Felix J, Elegheert J, Gutsche I, Shkumatov AV, Wen Y, Bracke N, Pannecoucke E, Vandenberghe I, Devreese B, Svergun DI, Pauwels E, Vergauwen B, Savvides SN

Structure (London, England : 1993) 2013

doi:10.1016/j.str.2013.01.018.

Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid

Nowak E, Potrzebowski W, Konarev PV, Rausch JW, Bona MK, Svergun DI, Bujnicki JM, Le Grice SF, Nowotny M

Nucleic acids research 2013

doi:10.1093/nar/gkt053.

Self-assembly and conformational heterogeneity of the AXH domain of ataxin-1: an unusual example of a chameleon fold

de Chiara C, Rees M, Menon RP, Pauwels K, Lawrence C, Konarev PV, Svergun DI, Martin SR, Chen YW, Pastore A

Biophysical journal 2013

doi:10.1016/j.bpj.2013.01.048.

The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization

Söderberg CA, Rajan S, Shkumatov AV, Gakh O, Schaefer S, Ahlgren EC, Svergun DI, Isaya G, Al-Karadaghi S

The Journal of biological chemistry 2013

doi:10.1074/jbc.m112.442285.

Quaternary structure of human, Drosophila melanogaster and Caenorhabditis elegans MFE-2 in solution from synchrotron small-angle X-ray scattering

Mehtälä ML, Haataja TJ, Blanchet CE, Hiltunen JK, Svergun DI, Glumoff T

FEBS letters 2013

doi:10.1016/j.febslet.2012.12.014.

Applications of small-angle X-ray scattering to biomacromolecular solutions

Petoukhov MV, Svergun DI

The international journal of biochemistry & cell biology 2013

doi:10.1016/j.biocel.2012.10.017.

Comparative Characterization of Apo-, Reconstituted- and In Vivo-Folded forms of a Durum Wheat Metallothionein

Sayers Z, Aydin M, Bal E, Yesilirmak F, Konarev PV, Petoukhov MV, Roessle M, Kikhney AG, Shang WF, Svergun DI

BIOPHYSICAL JOURNAL 2013

doi:10.1016/j.bpj.2012.11.2209.

Small-angle X-ray scattering on biological macromolecules and nanocomposites in solution

Blanchet CE, Svergun DI

Annual review of physical chemistry 2013

doi:10.1146/annurev-physchem-040412-110132.

Quaternary structure of the yeast Arc1p-aminoacyl-tRNA synthetase complex in solution and its compaction upon binding of tRNAs

Koehler C, Round A, Simader H, Suck D, Svergun D

Nucleic acids research 2013

doi:10.1093/nar/gks1072.

Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein

Lamber EP, Beuron F, Morris EP, Svergun DI, Mittnacht S

PloS one 2013

doi:10.1371/journal.pone.0058463.

Ceruloplasmin: macromolecular assemblies with iron-containing acute phase proteins

Samygina VR, Sokolov AV, Bourenkov G, Petoukhov MV, Pulina MO, Zakharova ET, Vasilyev VB, Bartunik H, Svergun DI

PloS one 2013

doi:10.1371/journal.pone.0067145.

Structural analysis of influenza A virus matrix protein M1 and its self-assemblies at low pH

Shtykova EV, Baratova LA, Fedorova NV, Radyukhin VA, Ksenofontov AL, Volkov VV, Shishkov AV, Dolgov AA, Shilova LA, Batishchev OV, Jeffries CM, Svergun DI

PloS one 2013

doi:10.1371/journal.pone.0082431.

The asymmetric binding of PGC-1α to the ERRα and ERRγ nuclear receptor homodimers involves a similar recognition mechanism

Takacs M, Petoukhov MV, Atkinson RA, Roblin P, Ogi FX, Demeler B, Potier N, Chebaro Y, Dejaegere A, Svergun DI, Moras D, Billas IM

PloS one 2013

doi:10.1371/journal.pone.0067810.

Structural and functional integration of the PLCγ interaction domains critical for regulatory mechanisms and signaling deregulation

Bunney TD, Esposito D, Mas-Droux C, Lamber E, Baxendale RW, Martins M, Cole A, Svergun D, Driscoll PC, Katan M

Structure (London, England : 1993) 2012

doi:10.1016/j.str.2012.09.005.

Solution structure of CCP modules 10-12 illuminates functional architecture of the complement regulator, factor H

Makou E, Mertens HD, Maciejewski M, Soares DC, Matis I, Schmidt CQ, Herbert AP, Svergun DI, Barlow PN

Journal of molecular biology 2012

doi:10.1016/j.jmb.2012.09.013.

WeNMR: Structural Biology on the Grid

Wassenaar TA, van Dijk M, Loureiro-Ferreira N, van der Schot G, de Vries JA, Schmitz C, van der Zwan J, Boelens R, Giachetti A, Ferella L, Rosato A, Bertini I, Herrmann T, Jonker HRA, Bagaria A, Jaravine V, Güntert P, Schwalbe H, Vranken WF, Doreleijers JF, Vriend G, Vuister GW, Franke D, Kikhney A, Svergun DI, Fogh RH, Ionides J, Laue ED, Spronk C, Jurkša S, Verlato M, Badoer S, Dal Pra S, Mazzucato M, Frizziero E, Bonvin AMJJ

Journal of Grid Computing 2012

doi:10.1007/s10723-012-9246-z.

A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR)

Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M

The Journal of biological chemistry 2012

doi:10.1074/jbc.m112.398404.

Structural insights into the regulatory mechanism of the response regulator RocR from Pseudomonas aeruginosa in cyclic Di-GMP signaling

Chen MW, Kotaka M, Vonrhein C, Bricogne G, Rao F, Chuah ML, Svergun D, Schneider G, Liang ZX, Lescar J

Journal of bacteriology 2012

doi:10.1128/jb.00560-12.

Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1

Elegheert J, Bracke N, Pouliot P, Gutsche I, Shkumatov AV, Tarbouriech N, Verstraete K, Bekaert A, Burmeister WP, Svergun DI, Lambrecht BN, Vergauwen B, Savvides SN

Nature structural & molecular biology 2012

doi:10.1038/nsmb.2367.

Structural flexibility of RNA as molecular basis for Hfq chaperone function

Ribeiro Ede A Jr, Beich-Frandsen M, Konarev PV, Shang W, Vecerek B, Kontaxis G, Hämmerle H, Peterlik H, Svergun DI, Bläsi U, Djinović-Carugo K

Nucleic acids research 2012

doi:10.1093/nar/gks510.

The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4

Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, Owen-Hughes T, Svergun DI, Gileadi O, Laue ED

Journal of molecular biology 2012

doi:10.1016/j.jmb.2012.04.031.

MaxOcc: a web portal for maximum occurrence analysis

Bertini I, Ferella L, Luchinat C, Parigi G, Petoukhov MV, Ravera E, Rosato A, Svergun DI

Journal of biomolecular NMR 2012

doi:10.1007/s10858-012-9638-1.

Macromolecular HPMA-based nanoparticles with cholesterol for solid-tumor targeting: detailed study of the inner structure of a highly efficient drug delivery system

Filippov SK, Chytil P, Konarev PV, Dyakonova M, Papadakis C, Zhigunov A, Plestil J, Stepanek P, Etrych T, Ulbrich K, Svergun DI

Biomacromolecules 2012

doi:10.1021/bm3008555.

High concentration formulation studies of an IgG2 antibody using small angle X-ray scattering

Mosbæk CR, Konarev PV, Svergun DI, Rischel C, Vestergaard B

Pharmaceutical research 2012

doi:10.1007/s11095-012-0751-3.

Identification of an N-terminal inhibitory extension as the primary mechanosensory regulator of twitchin kinase

von Castelmur E, Strümpfer J, Franke B, Bogomolovas J, Barbieri S, Qadota H, Konarev PV, Svergun DI, Labeit S, Benian GM, Schulten K, Mayans O

Proceedings of the National Academy of Sciences of the United States of America 2012

doi:10.1073/pnas.1200697109.

Ligand-binding properties and conformational dynamics of autolysin repeat domains in staphylococcal cell wall recognition

Zoll S, Schlag M, Shkumatov AV, Rautenberg M, Svergun DI, Götz F, Stehle T

Journal of bacteriology 2012

doi:10.1128/jb.00331-12.

Solution structure of the natively assembled yeast ribosomal stalk determined by small-angle X-ray scattering

Grela P, Gajda MJ, Armache JP, Beckmann R, Krokowski D, Svergun DI, Grankowski N, Tchórzewski M

The Biochemical journal 2012

doi:10.1042/bj20120115.

Publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution

Jacques DA, Guss JM, Svergun DI, Trewhella J

Acta crystallographica. Section D, Biological crystallography 2012

doi:10.1107/s0907444912012073.

Conformational analysis of a genetically encoded FRET biosensor by SAXS

Mertens HD, Piljić A, Schultz C, Svergun DI

Biophysical journal 2012

doi:10.1016/j.bpj.2012.05.009.

Direct intracellular selection and biochemical characterization of a recombinant anti-proNGF single chain antibody fragment

Paoletti F, Malerba F, Konarev PV, Visintin M, Scardigli R, Fasulo L, Lamba D, Svergun DI, Cattaneo A

Archives of biochemistry and biophysics 2012

doi:10.1016/j.abb.2012.04.003.

Unusual Structural Morphology of Dendrimer/CdS Nanocomposites Revealed by Synchrotron X-ray Scattering

Shtykoya EV, Kuchkina NV, Shifrina ZB, Bronstein LM, Svergun DI

JOURNAL OF PHYSICAL CHEMISTRY C 2012

doi:10.1021/jp210998h.

The role of hydration in protein stability: comparison of the cold and heat unfolded states of Yfh1

Adrover M, Martorell G, Martin SR, Urosev D, Konarev PV, Svergun DI, Daura X, Temussi P, Pastore A

Journal of molecular biology 2012

doi:10.1016/j.jmb.2012.02.002.

Structural investigation of prion protein conversion induced by oxidative stress

Redecke L, Sommer A, Elmallah M, Rehders D, Kikhney A, Binder S, Svergun D, Rubhausen M, Betzel C

PRION 2012

doi:.

Solution model of the intrinsically disordered polyglutamine tract-binding protein-1

Rees M, Gorba C, de Chiara C, Bui TT, Garcia-Maya M, Drake AF, Okazawa H, Pastore A, Svergun D, Chen YW

Biophysical journal 2012

doi:10.1016/j.bpj.2012.02.047.

Nonstructural proteins 7 and 8 of feline coronavirus form a 2:1 heterotrimer that exhibits primer-independent RNA polymerase activity

Xiao Y, Ma Q, Restle T, Shang W, Svergun DI, Ponnusamy R, Sczakiel G, Hilgenfeld R

Journal of virology 2012

doi:10.1128/jvi.06635-11.

Crystal structure of Pseudomonas aeruginosa Tsi2 reveals a stably folded superhelical antitoxin

Zou T, Yao X, Qin B, Zhang M, Cai L, Shang W, Svergun DI, Wang M, Cui S, Jin Q

Journal of molecular biology 2012

doi:10.1016/j.jmb.2012.01.040.

Ligand-induced formation of transient dimers of mammalian 12/15-lipoxygenase: a key to allosteric behavior of this class of enzymes?

Ivanov I, Shang W, Toledo L, Masgrau L, Svergun DI, Stehling S, Gómez H, Di Venere A, Mei G, Lluch JM, Skrzypczak-Jankun E, González-Lafont A, Kühn H

Proteins 2012

doi:10.1002/prot.23227.

The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly

Marrott NL, Marshall JJ, Svergun DI, Crennell SJ, Hough DW, Danson MJ, van den Elsen JM

The FEBS journal 2012

doi:10.1111/j.1742-4658.2011.08461.x.

A flexible brace maintains the assembly of a hexameric replicative helicase during DNA unwinding

Whelan F, Stead JA, Shkumatov AV, Svergun DI, Sanders CM, Antson AA

Nucleic acids research 2012

doi:10.1093/nar/gkr906.

Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties

Pinotsis N, Chatziefthimiou SD, Berkemeier F, Beuron F, Mavridis IM, Konarev PV, Svergun DI, Morris E, Rief M, Wilmanns M

PLoS biology 2012

doi:10.1371/journal.pbio.1001261.

Stretching of Twitchin Kinase

Strumpfer JA, von Castelmur E, Franke B, Barbieri S, Bogomolovas J, Qadota H, Konarv P, Svergun D, Labeit S, Schulten K, Benian GM, Mayans O

BIOPHYSICAL JOURNAL 2012

doi:10.1016/j.bpj.2011.11.1973.

Analysis of intrinsically disordered proteins by small-angle X-ray scattering

Bernadó P, Svergun DI

Methods in molecular biology (Clifton, N.J.) 2012

doi:10.1007/978-1-4614-3704-8_7.

Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering

Bernadó P, Svergun DI

Molecular bioSystems 2012

doi:10.1039/c1mb05275f.

Instrumental setup for high-throughput small- and wide-angle solution scattering at the X33 beamline of EMBL Hamburg

Blanchet CE, Zozulya AV, Kikhney AG, Franke D, Konarev PV, Shang WF, Klaering R, Robrahn B, Hermes C, Cipriani F, Svergun DI, Roessle M

Journal of applied crystallography 2012

doi:10.1107/S0021889812013490.

Automated acquisition and analysis of small angle X-ray scattering data

Franke D, Kikhney AG, Svergun DI

Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment 2012

doi:10.1016/j.nima.2012.06.008.

Structural analysis of the C-terminal region (modules 18-20) of complement regulator factor H (FH)

Morgan HP, Mertens HD, Guariento M, Schmidt CQ, Soares DC, Svergun DI, Herbert AP, Barlow PN, Hannan JP

PloS one 2012

doi:10.1371/journal.pone.0032187.

Solution Structures of PPARγ2/RXRα Complexes

Osz J, Pethoukhov MV, Sirigu S, Svergun DI, Moras D, Rochel N

PPAR research 2012

doi:10.1155/2012/701412.

New developments in the ATSAS program package for small-angle scattering data analysis

Petoukhov MV, Franke D, Shkumatov AV, Tria G, Kikhney AG, Gajda M, Gorba C, Mertens HDT, Konarev PV, Svergun DI

Journal of applied crystallography 2012

doi:10.1107/S0021889812007662.

Small Angle X-Ray Scattering/Small Angle Neutron Scattering as Methods Complementary to NMR.

Petoukhov MV, Svergun DI

2012

doi:.

The Vibrio cholerae colonization factor GbpA possesses a modular structure that governs binding to different host surfaces

Wong E, Vaaje-Kolstad G, Ghosh A, Hurtado-Guerrero R, Konarev PV, Ibrahim AF, Svergun DI, Eijsink VG, Chatterjee NS, van Aalten DM

PLoS pathogens 2012

doi:10.1371/journal.ppat.1002373.

Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles

Elegheert J, Desfosses A, Shkumatov AV, Wu X, Bracke N, Verstraete K, Van Craenenbroeck K, Brooks BR, Svergun DI, Vergauwen B, Gutsche I, Savvides SN

Structure (London, England : 1993) 2011

doi:10.1016/j.str.2011.10.012.

Structural and functional insights into a dodecameric molecular machine - the RuvBL1/RuvBL2 complex

Gorynia S, Bandeiras TM, Pinho FG, McVey CE, Vonrhein C, Round A, Svergun DI, Donner P, Matias PM, Carrondo MA

Journal of structural biology 2011

doi:10.1016/j.jsb.2011.09.001.

A macrocyclic HCV NS3/4A protease inhibitor interacts with protease and helicase residues in the complex with its full-length target

Schiering N, D'Arcy A, Villard F, Simic O, Kamke M, Monnet G, Hassiepen U, Svergun DI, Pulfer R, Eder J, Raman P, Bodendorf U

Proceedings of the National Academy of Sciences of the United States of America 2011

doi:10.1073/pnas.1110534108.

Oligomerization propensity and flexibility of yeast frataxin studied by X-ray crystallography and small-angle X-ray scattering

Söderberg CA, Shkumatov AV, Rajan S, Gakh O, Svergun DI, Isaya G, Al-Karadaghi S

Journal of molecular biology 2011

doi:10.1016/j.jmb.2011.10.034.

Structure of the Lassa virus nucleoprotein revealed by X-ray crystallography, small-angle X-ray scattering, and electron microscopy

Brunotte L, Kerber R, Shang W, Hauer F, Hass M, Gabriel M, Lelke M, Busch C, Stark H, Svergun DI, Betzel C, Perbandt M, Günther S

The Journal of biological chemistry 2011

doi:10.1074/jbc.m111.278838.

Insights into the molecular activation mechanism of the RhoA-specific guanine nucleotide exchange factor, PDZRhoGEF

Bielnicki JA, Shkumatov AV, Derewenda U, Somlyo AV, Svergun DI, Derewenda ZS

The Journal of biological chemistry 2011

doi:10.1074/jbc.m111.270918.

Essential role of the metal-ion in the IPM-assisted domain closure of 3-isopropylmalate dehydrogenase

Gráczer E, Konarev PV, Szimler T, Bacsó A, Bodonyi A, Svergun DI, Závodszky P, Vas M

FEBS letters 2011

doi:10.1016/j.febslet.2011.09.013.

Solution structure of the soluble receptor for advanced glycation end products (sRAGE)

Sárkány Z, Ikonen TP, Ferreira-da-Silva F, Saraiva MJ, Svergun D, Damas AM

The Journal of biological chemistry 2011

doi:10.1074/jbc.m111.223438.

Small-Angle X-Ray Scattering, Synchrotron Radiation, and the Structure of Bio- and Nanosystems

Svergun DI, Shtykova EV, Volkov VV, Feigin LA

CRYSTALLOGRAPHY REPORTS 2011

doi:10.1134/S1063774511050221.

Structure-function relationships in different MFE-2 proteins by various biophysical techniques

Mehtala M, Haataja T, Blanchet C, Lensink M, Hiltunen K, Svergun D, Glumoff T

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 2011

doi:.

Solution structure and self assembly properties of soluble RAGE

Sarkany Z, Ikonen T, Ferreira-da-Silva F, Saraiva MJ, Svergun D, Damas AM

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 2011

doi:.

"4D Biology for health and disease" workshop report

Abrahams JP, Apweiler R, Balling R, Bertero MG, Bujnicki JM, Chayen NE, Chène P, Corthals GL, Dyląg T, Förster F, Heck AJ, Henderson PJ, Herwig R, Jehenson P, Kokalj SJ, Laue E, Legrain P, Martens L, Migliorini C, Musacchio A, Podobnik M, Schertler GF, Schreiber G, Sixma TK, Smit AB, Stuart D, Svergun DI, Taussig MJ

New biotechnology 2011

doi:10.1016/j.nbt.2010.10.003.

Structural memory of natively unfolded tau protein detected by small-angle X-ray scattering

Shkumatov AV, Chinnathambi S, Mandelkow E, Svergun DI

Proteins 2011

doi:10.1002/prot.23033.

Structural insights into the extracellular assembly of the hematopoietic Flt3 signaling complex

Verstraete K, Vandriessche G, Januar M, Elegheert J, Shkumatov AV, Desfosses A, Van Craenenbroeck K, Svergun DI, Gutsche I, Vergauwen B, Savvides SN

Blood 2011

doi:10.1182/blood-2011-01-329532.

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq

Beich-Frandsen M, Vecerek B, Konarev PV, Sjöblom B, Kloiber K, Hämmerle H, Rajkowitsch L, Miles AJ, Kontaxis G, Wallace BA, Svergun DI, Konrat R, Bläsi U, Djinovic-Carugo K

Nucleic acids research 2011

doi:10.1093/nar/gkq1346.

Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering

Shang W, Ivanov I, Svergun DI, Borbulevych OY, Aleem AM, Stehling S, Jankun J, Kühn H, Skrzypczak-Jankun E

Journal of molecular biology 2011

doi:10.1016/j.jmb.2011.04.035.

Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings

Rochel N, Ciesielski F, Godet J, Moman E, Roessle M, Peluso-Iltis C, Moulin M, Haertlein M, Callow P, Mély Y, Svergun DI, Moras D

Nature structural & molecular biology 2011

doi:10.1038/nsmb.2054.

Small-angle X-ray scattering study of a Rex family repressor: conformational response to NADH and NAD+ binding in solution

Wang E, Ikonen TP, Knaapila M, Svergun D, Logan DT, von Wachenfeldt C

Journal of molecular biology 2011

doi:10.1016/j.jmb.2011.02.050.

Structural basis for engagement by complement factor H of C3b on a self surface

Morgan HP, Schmidt CQ, Guariento M, Blaum BS, Gillespie D, Herbert AP, Kavanagh D, Mertens HD, Svergun DI, Johansson CM, Uhrín D, Barlow PN, Hannan JP

Nature structural & molecular biology 2011

doi:10.1038/nsmb.2018.

The dimer interface of the membrane type 1 matrix metalloproteinase hemopexin domain: crystal structure and biological functions

Tochowicz A, Goettig P, Evans R, Visse R, Shitomi Y, Palmisano R, Ito N, Richter K, Maskos K, Franke D, Svergun D, Nagase H, Bode W, Itoh Y

The Journal of biological chemistry 2011

doi:10.1074/jbc.m110.178434.

Low-resolution structure of a vesicle disrupting α-synuclein oligomer that accumulates during fibrillation

Giehm L, Svergun DI, Otzen DE, Vestergaard B

Proceedings of the National Academy of Sciences of the United States of America 2011

doi:10.1073/pnas.1013225108.

A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d

Clark EA, Crennell S, Upadhyay A, Zozulya AV, Mackay JD, Svergun DI, Bagby S, van den Elsen JM

Molecular immunology 2011

doi:10.1016/j.molimm.2010.09.017.

Engineered synthetic virus-like particles and their use in vaccine delivery

Ghasparian A, Riedel T, Koomullil J, Moehle K, Gorba C, Svergun DI, Perriman AW, Mann S, Tamborrini M, Pluschke G, Robinson JA

Chembiochem : a European journal of chemical biology 2011

doi:10.1002/cbic.201000536.

Structural characterization of the multidomain regulatory protein Rv1364c from Mycobacterium tuberculosis

King-Scott J, Konarev PV, Panjikar S, Jordanova R, Svergun DI, Tucker PA

Structure (London, England : 1993) 2011

doi:10.1016/j.str.2010.11.010.

The structure of the unliganded extracellular domain of the interleukin-6 signal transducer gp130 in solution

Lorenzen I, Shang W, Perbandt M, Petoukhov MV, Svergun DI, Waetzig GH, Rose-John S, Hilgenfeld R, Grötzinger J

European journal of cell biology 2011

doi:10.1016/j.ejcb.2010.09.012.

Structural studies on the enzyme complex isopropylmalate isomerase (LeuCD) from Mycobacterium tuberculosis

Manikandan K, Geerlof A, Zozulya AV, Svergun DI, Weiss MS

Proteins 2011

doi:10.1002/prot.22856.

Hydrophilization of Magnetic Nanoparticles with Modified Alternating Copolymers. Part 1: The Influence of the Grafting

Bronstein LM, Shtykova EV, Malyutin A, Dyke JC, Gunn E, Gao X, Stein B, Konarev PV, Dragnea B, Svergun DI

The journal of physical chemistry. C, Nanomaterials and interfaces 2010

doi:10.1021/jp107283w.

Crystal structure of hexokinase KlHxk1 of Kluyveromyces lactis: a molecular basis for understanding the control of yeast hexokinase functions via covalent modification and oligomerization

Kuettner EB, Kettner K, Keim A, Svergun DI, Volke D, Singer D, Hoffmann R, Müller EC, Otto A, Kriegel TM, Sträter N

The Journal of biological chemistry 2010

doi:10.1074/jbc.m110.185850.

Hydrophilization of Magnetic Nanoparticles with Modified Alternating Copolymers. Part 2: Behavior in solution

Shtykova EV, Malyutin A, Dyke J, Stein B, Konarev PV, Dragnea B, Svergun DI, Bronstein LM

The journal of physical chemistry. C, Nanomaterials and interfaces 2010

doi:10.1021/jp1072846.

Recognition of nucleoplasmin by its nuclear transport receptor importin α/β: insights into a complete import complex

Falces J, Arregi I, Konarev PV, Urbaneja MA, Svergun DI, Taneva SG, Bañuelos S

Biochemistry 2010

doi:10.1021/bi101179g.

Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility

Mosbaek CR, Nolan D, Persson E, Svergun DI, Bukrinsky JT, Vestergaard B

Biochemistry 2010

doi:10.1021/bi1011207.

The switch that does not flip: the blue-light receptor YtvA from Bacillus subtilis adopts an elongated dimer conformation independent of the activation state as revealed by a combined AUC and SAXS study

Jurk M, Dorn M, Kikhney A, Svergun D, Gärtner W, Schmieder P

Journal of molecular biology 2010

doi:10.1016/j.jmb.2010.08.036.

Structural characterization of proteins and complexes using small-angle X-ray solution scattering

Mertens HD, Svergun DI

Journal of structural biology 2010

doi:10.1016/j.jsb.2010.06.012.

Structural characterization of protein-protein complexes by integrating computational docking with small-angle scattering data

Pons C, D'Abramo M, Svergun DI, Orozco M, Bernadó P, Fernández-Recio J

Journal of molecular biology 2010

doi:10.1016/j.jmb.2010.08.029.

Conformational space of flexible biological macromolecules from average data

Bertini I, Giachetti A, Luchinat C, Parigi G, Petoukhov MV, Pierattelli R, Ravera E, Svergun DI

Journal of the American Chemical Society 2010

doi:10.1021/ja1063923.

The structure of the FnIII Tandem A77-A78 points to a periodically conserved architecture in the myosin-binding region of titin

Bucher RM, Svergun DI, Muhle-Goll C, Mayans O

Journal of molecular biology 2010

doi:10.1016/j.jmb.2010.06.011.

Small-angle X-ray and neutron scattering as a tool for structural systems biology

Svergun DI

Biological chemistry 2010

doi:10.1515/bc.2010.093.

Structure and Dynamics of Ribosomal Protein L12: An Ensemble Model Based on SAXS and NMR Relaxation

Bernadó P, Modig K, Grela P, Svergun DI, Tchorzewski M, Pons M, Akke M

Biophysical journal 2010

doi:10.1016/j.bpj.2010.02.012.

Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS

Albesa-Jové D, Bertrand T, Carpenter EP, Swain GV, Lim J, Zhang J, Haire LF, Vasisht N, Braun V, Lange A, von Eichel-Streiber C, Svergun DI, Fairweather NF, Brown KA

Journal of molecular biology 2010

doi:10.1016/j.jmb.2010.01.012.

Low Resolution Structure of a Membrane-Permeabilizing Oligomer of alpha-Synuclein: the Basis for a High-Throughput Screening of Compounds against alpha-Synuclein Aggregation

Giehm L, Vestergaard B, Oliveira C, Pedersen JS, Svergun DI, Pitts K, Krishnamurthy G, Staal R, Reinhart P, Otzen DE

BIOPHYSICAL JOURNAL 2010

doi:10.1016/j.bpj.2009.12.2291.

Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly

Prischi F, Konarev PV, Iannuzzi C, Pastore C, Adinolfi S, Martin SR, Svergun DI, Pastore A

Nature communications 2010

doi:10.1038/ncomms1097.

The central portion of factor H (modules 10-15) is compact and contains a structurally deviant CCP module

Schmidt CQ, Herbert AP, Mertens HD, Guariento M, Soares DC, Uhrin D, Rowe AJ, Svergun DI, Barlow PN

Journal of molecular biology 2010

doi:10.1016/j.jmb.2009.10.010.

Metal-mediated self-assembly of a beta-sandwich protein

Crowley PB, Matias PM, Khan AR, Roessle M, Svergun DI

Chemistry (Weinheim an der Bergstrasse, Germany) 2009

doi:10.1002/chem.200901410.

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

De Marco V, Gillespie PJ, Li A, Karantzelis N, Christodoulou E, Klompmaker R, van Gerwen S, Fish A, Petoukhov MV, Iliou MS, Lygerou Z, Medema RH, Blow JJ, Svergun DI, Taraviras S, Perrakis A

Proceedings of the National Academy of Sciences of the United States of America 2009

doi:10.1073/pnas.0905281106.

The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA

Cierpicki T, Bielnicki J, Zheng M, Gruszczyk J, Kasterka M, Petoukhov M, Zhang A, Fernandez EJ, Svergun DI, Derewenda U, Bushweller JH, Derewenda ZS

Protein science : a publication of the Protein Society 2009

doi:10.1002/pro.219.

A mechanism for histone chaperoning activity of nucleoplasmin: thermodynamic and structural models

Taneva SG, Bañuelos S, Falces J, Arregi I, Muga A, Konarev PV, Svergun DI, Velázquez-Campoy A, Urbaneja MA

Journal of molecular biology 2009

doi:10.1016/j.jmb.2009.08.005.

Large-scale movement of functional domains facilitates aminoacylation by human mitochondrial phenylalanyl-tRNA synthetase

Yadavalli SS, Klipcan L, Zozulya A, Banerjee R, Svergun D, Safro M, Ibba M

FEBS letters 2009

doi:10.1016/j.febslet.2009.09.008.

The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties

Zeev-Ben-Mordehai T, Mylonas E, Paz A, Peleg Y, Toker L, Silman I, Svergun DI, Sussman JL

Biophysical journal 2009

doi:10.1016/j.bpj.2009.07.045.

A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase

Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, Grütter MG, Capitani G

Journal of molecular biology 2009

doi:10.1016/j.jmb.2009.06.080.

Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin

Heikkinen OK, Ruskamo S, Konarev PV, Svergun DI, Iivanainen T, Heikkinen SM, Permi P, Koskela H, Kilpeläinen I, Ylänne J

The Journal of biological chemistry 2009

doi:10.1074/jbc.m109.019661.

Solution structure of human Pex5.Pex14.PTS1 protein complexes obtained by small angle X-ray scattering

Shiozawa K, Konarev PV, Neufeld C, Wilmanns M, Svergun DI

The Journal of biological chemistry 2009

doi:10.1074/jbc.m109.002311.

The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation

Weyand S, Kefala G, Svergun DI, Weiss MS

Journal of structural and functional genomics 2009

doi:10.1007/s10969-009-9065-z.

Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex

Janssen BJ, Gomes L, Koning RI, Svergun DI, Koster AJ, Fritzinger DC, Vogel CW, Gros P

The EMBO journal 2009

doi:10.1038/emboj.2009.184.

Structural and biophysical characterization of the proteins interacting with the herpes simplex virus 1 origin of replication

Manolaridis I, Mumtsidu E, Konarev P, Makhov AM, Fullerton SW, Sinz A, Kalkhof S, McGeehan JE, Cary PD, Griffith JD, Svergun D, Kneale GG, Tucker PA

The Journal of biological chemistry 2009

doi:10.1074/jbc.m806134200.

Intrinsic structural disorder of mouse proNGF

Paoletti F, Covaceuszach S, Konarev PV, Gonfloni S, Malerba F, Schwarz E, Svergun DI, Cattaneo A, Lamba D

Proteins 2009

doi:10.1002/prot.22311.

A crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments

Pires R, Hartlieb B, Signor L, Schoehn G, Lata S, Roessle M, Moriscot C, Popov S, Hinz A, Jamin M, Boyer V, Sadoul R, Forest E, Svergun DI, Göttlinger HG, Weissenhorn W

Structure (London, England : 1993) 2009

doi:10.1016/j.str.2009.04.007.

Structural and functional characterization of soluble endoglin receptor

Van Le B, Franke D, Svergun DI, Han T, Hwang HY, Kim KK

Biochemical and biophysical research communications 2009

doi:10.1016/j.bbrc.2009.02.162.

Characterization of a fluorophore binding RNA aptamer by fluorescence correlation spectroscopy and small angle X-ray scattering

Werner A, Konarev PV, Svergun DI, Hahn U

Analytical biochemistry 2009

doi:10.1016/j.ab.2009.03.018.

Rigidity, conformation, and solvation of native and oxidized tannin macromolecules in water-ethanol solution

Zanchi D, Konarev PV, Tribet C, Baron A, Svergun DI, Guyot S

The Journal of chemical physics 2009

doi:10.1063/1.3156020.

Interdomain flexibility in full-length matrix metalloproteinase-1 (MMP-1)

Bertini I, Fragai M, Luchinat C, Melikian M, Mylonas E, Sarti N, Svergun DI

The Journal of biological chemistry 2009

doi:10.1074/jbc.m809627200.

Structural insights into eRF3 and stop codon recognition by eRF1

Cheng Z, Saito K, Pisarev AV, Wada M, Pisareva VP, Pestova TV, Gajda M, Round A, Kong C, Lim M, Nakamura Y, Svergun DI, Ito K, Song H

Genes & development 2009

doi:10.1101/gad.1770109.

Structural characterization of unphosphorylated STAT5a oligomerization equilibrium in solution by small-angle X-ray scattering

Bernadó P, Pérez Y, Blobel J, Fernández-Recio J, Svergun DI, Pons M

Protein science : a publication of the Protein Society 2009

doi:10.1002/pro.83.

Low-resolution structures of transient protein-protein complexes using small-angle X-ray scattering

Blobel J, Bernadó P, Svergun DI, Tauler R, Pons M

Journal of the American Chemical Society 2009

doi:10.1021/ja808490b.

Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra

Maveyraud L, Niwa H, Guillet V, Svergun DI, Konarev PV, Palmer RA, Peumans WJ, Rougé P, Van Damme EJ, Reynolds CD, Mourey L

Proteins 2009

doi:10.1002/prot.22222.

A study of the ultrastructure of fragile-X-related proteins

Sjekloća L, Konarev PV, Eccleston J, Taylor IA, Svergun DI, Pastore A

The Biochemical journal 2009

doi:10.1042/bj20082197.

Structural insights into the molecular organization of the S-layer from Clostridium difficile

Fagan RP, Albesa-Jové D, Qazi O, Svergun DI, Brown KA, Fairweather NF

Molecular microbiology 2009

doi:10.1111/j.1365-2958.2009.06603.x.

Kinetic and mechanistic characterization of Mycobacterium tuberculosis glutamyl-tRNA synthetase and determination of its oligomeric structure in solution

Paravisi S, Fumagalli G, Riva M, Morandi P, Morosi R, Konarev PV, Petoukhov MV, Bernier S, Chênevert R, Svergun DI, Curti B, Vanoni MA

The FEBS journal 2009

doi:10.1111/j.1742-4658.2009.06880.x.

Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers

Takács E, Barabás O, Petoukhov MV, Svergun DI, Vértessy BG

FEBS letters 2009

doi:10.1016/j.febslet.2009.02.011.

DAMMIF, a program for rapid ab-initio shape determination in small-angle scattering

Franke D, Svergun DI

Journal of applied crystallography 2009

doi:.

Colloidal stability of tannins: astringency, wine tasting and beyond

Zanchi D, Poulain C, Konarev P, Tribet C, Svergun DI

JOURNAL OF PHYSICS-CONDENSED MATTER 2008

doi:10.1088/0953-8984/20/49/494224.

A different conformation for EGC stator subcomplex in solution and in the assembled yeast V-ATPase: possible implications for regulatory disassembly

Diepholz M, Venzke D, Prinz S, Batisse C, Flörchinger B, Rössle M, Svergun DI, Böttcher B, Féthière J

Structure (London, England : 1993) 2008

doi:10.1016/j.str.2008.09.010.

Mixed Co/Fe oxide nanoparticles in block copolymer micelles

Bronstein LM, Kostylev M, Shtykova E, Vlahu T, Huang X, Stein BD, Bykov A, Remmes NB, Baxter DV, Svergun DI

Langmuir : the ACS journal of surfaces and colloids 2008

doi:10.1021/la8021276.

3- Instead of 4-helix formation in a de novo designed protein in solution revealed by small-angle X-ray scattering

Høiberg-Nielsen R, Tofteng Shelton AP, Sørensen KK, Roessle M, Svergun DI, Thulstrup PW, Jensen KJ, Arleth L

Chembiochem : a European journal of chemical biology 2008

doi:10.1002/cbic.200800263.

Automated sample-changing robot for solution scattering experiments at the EMBL Hamburg SAXS station X33

Round AR, Franke D, Moritz S, Huchler R, Fritsche M, Malthan D, Klaering R, Svergun DI, Roessle M

JOURNAL OF APPLIED CRYSTALLOGRAPHY 2008

doi:10.1107/S0021889808021018.

Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody

Covaceuszach S, Cassetta A, Konarev PV, Gonfloni S, Rudolph R, Svergun DI, Lamba D, Cattaneo A

Journal of molecular biology 2008

doi:10.1016/j.jmb.2008.06.008.

Domain conformation of tau protein studied by solution small-angle X-ray scattering

Mylonas E, Hascher A, Bernadó P, Blackledge M, Mandelkow E, Svergun DI

Biochemistry 2008

doi:10.1021/bi800900d.

Quaternary structure of flavorubredoxin as revealed by synchrotron radiation small-angle X-ray scattering

Petoukhov MV, Vicente JB, Crowley PB, Carrondo MA, Teixeira M, Svergun DI

Structure (London, England : 1993) 2008

doi:10.1016/j.str.2008.06.009.

A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints

Gabel F, Simon B, Nilges M, Petoukhov M, Svergun D, Sattler M

Journal of biomolecular NMR 2008

doi:10.1007/s10858-008-9258-y.

Structural relationships among the ribosomal stalk proteins from the three domains of life

Grela P, Bernadó P, Svergun D, Kwiatowski J, Abramczyk D, Grankowski N, Tchórzewski M

Journal of molecular evolution 2008

doi:10.1007/s00239-008-9132-2.

The structure and binding behavior of the bacterial cell surface layer protein SbsC

Pavkov T, Egelseer EM, Tesarz M, Svergun DI, Sleytr UB, Keller W

Structure (London, England : 1993) 2008

doi:10.1016/j.str.2008.05.012.

Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3

Paz A, Zeev-Ben-Mordehai T, Lundqvist M, Sherman E, Mylonas E, Weiner L, Haran G, Svergun DI, Mulder FA, Sussman JL, Silman I

Biophysical journal 2008

doi:10.1529/biophysj.107.126995.

Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis

Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R

Journal of bacteriology 2008

doi:10.1128/jb.01988-07.

Selective deuteration of tryptophan and methionine residues in maltose binding protein: a model system for neutron scattering

Laux V, Callow P, Svergun DI, Timmins PA, Forsyth VT, Haertlein M

European biophysics journal : EBJ 2008

doi:10.1007/s00249-008-0280-5.

Communication between the nucleotide site and the main molecular hinge of 3-phosphoglycerate kinase

Szabó J, Varga A, Flachner B, Konarev PV, Svergun DI, Závodszky P, Vas M

Biochemistry 2008

doi:10.1021/bi800411w.

Evidence of reciprocal reorientation of the catalytic and hemopexin-like domains of full-length MMP-12

Bertini I, Calderone V, Fragai M, Jaiswal R, Luchinat C, Melikian M, Mylonas E, Svergun DI

Journal of the American Chemical Society 2008

doi:10.1021/ja710491y.

Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel mechanism of complement evasion by Staphylococcus aureus

Burman JD, Leung E, Atkins KL, O'Seaghdha MN, Lango L, Bernadó P, Bagby S, Svergun DI, Foster TJ, Isenman DE, van den Elsen JM

The Journal of biological chemistry 2008

doi:10.1074/jbc.m800265200.

Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding

Riek U, Scholz R, Konarev P, Rufer A, Suter M, Nazabal A, Ringler P, Chami M, Müller SA, Neumann D, Forstner M, Hennig M, Zenobi R, Engel A, Svergun D, Schlattner U, Wallimann T

The Journal of biological chemistry 2008

doi:10.1074/jbc.m708379200.

Characterization of Der p 21, a new important allergen derived from the gut of house dust mites

Weghofer M, Dall'Antonia Y, Grote M, Stöcklinger A, Kneidinger M, Balic N, Krauth MT, Fernández-Caldas E, Thomas WR, van Hage M, Vieths S, Spitzauer S, Horak F, Svergun DI, Konarev PV, Valent P, Thalhamer J, Keller W, Valenta R, Vrtala S

Allergy 2008

doi:10.1111/j.1398-9995.2008.01647.x.

Small angle X-ray studies reveal that Aspergillus niger glucoamylase has a defined extended conformation and can form dimers in solution

Jørgensen AD, Nøhr J, Kastrup JS, Gajhede M, Sigurskjold BW, Sauer J, Svergun DI, Svensson B, Vestergaard B

The Journal of biological chemistry 2008

doi:10.1074/jbc.m801709200.

Structural basis for autoinhibition of ESCRT-III CHMP3

Lata S, Roessle M, Solomons J, Jamin M, Gottlinger HG, Svergun DI, Weissenhorn W

Journal of molecular biology 2008

doi:10.1016/j.jmb.2008.03.030.

Dynamics in a pure encounter complex of two proteins studied by solution scattering and paramagnetic NMR spectroscopy

Xu X, Reinle W, Hannemann F, Konarev PV, Svergun DI, Bernhardt R, Ubbink M

Journal of the American Chemical Society 2008

doi:10.1021/ja7101357.

Absence of equilibrium cluster phase in concentrated lysozyme solutions

Shukla A, Mylonas E, Di Cola E, Finet S, Timmins P, Narayanan T, Svergun DI

Proceedings of the National Academy of Sciences of the United States of America 2008

doi:10.1073/pnas.0711928105.

Role of side-chains in the operation of the main molecular hinge of 3-phosphoglycerate kinase

Szabó J, Varga A, Flachner B, Konarev PV, Svergun DI, Závodszky P, Vas M

FEBS letters 2008

doi:10.1016/j.febslet.2008.03.016.

The subnanometer resolution structure of the glutamate synthase 1.2-MDa hexamer by cryoelectron microscopy and its oligomerization behavior in solution: functional implications

Cottevieille M, Larquet E, Jonic S, Petoukhov MV, Caprini G, Paravisi S, Svergun DI, Vanoni MA, Boisset N

The Journal of biological chemistry 2008

doi:10.1074/jbc.m708529200.

Fab MOR03268 triggers absorption shift of a diagnostic dye via packaging in a solvent-shielded Fab dimer interface

Hillig RC, Urlinger S, Fanghänel J, Brocks B, Haenel C, Stark Y, Sülzle D, Svergun DI, Baesler S, Malawski G, Moosmayer D, Menrad A, Schirner M, Licha K

Journal of molecular biology 2008

doi:10.1016/j.jmb.2007.12.071.

X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB

Niemann HH, Petoukhov MV, Härtlein M, Moulin M, Gherardi E, Timmins P, Heinz DW, Svergun DI

Journal of molecular biology 2008

doi:10.1016/j.jmb.2008.01.027.

Engineering the NK1 fragment of hepatocyte growth factor/scatter factor as a MET receptor antagonist

Youles M, Holmes O, Petoukhov MV, Nessen MA, Stivala S, Svergun DI, Gherardi E

Journal of molecular biology 2008

doi:10.1016/j.jmb.2008.01.034.

Human platelet 12-lipoxygenase, new findings about its activity, membrane binding and low-resolution structure

Aleem AM, Jankun J, Dignam JD, Walther M, Kühn H, Svergun DI, Skrzypczak-Jankun E

Journal of molecular biology 2008

doi:10.1016/j.jmb.2007.11.086.

Structural characterization of the active and inactive states of Src kinase in solution by small-angle X-ray scattering

Bernadó P, Pérez Y, Svergun DI, Pons M

Journal of molecular biology 2008

doi:10.1016/j.jmb.2007.11.066.

Structural features of the single-stranded DNA-binding protein of Epstein-Barr virus

Mumtsidu E, Makhov AM, Konarev PV, Svergun DI, Griffith JD, Tucker PA

Journal of structural biology 2008

doi:10.1016/j.jsb.2007.10.014.

Structural basis of dcp2 recognition and activation by dcp1

She M, Decker CJ, Svergun DI, Round A, Chen N, Muhlrad D, Parker R, Song H

Molecular cell 2008

doi:10.1016/j.molcel.2008.01.002.

Isolation and oligomeric composition of cytochrome c nitrite reductase from the haloalkaliphilic bacterium Thioalkalivibrio nitratireducens

Tikhonova TV, Slutskaya ES, Filimonenkov AA, Boyko KM, Kleimenov SY, Konarev PV, Polyakov KM, Svergun DI, Trofimov AA, Khomenkov VG, Zvyagilskaya RA, Popov VO

Biochemistry. Biokhimiia 2008

doi:10.1134/s0006297908020077.

Interaction of human 3-phosphoglycerate kinase with L-ADP, the mirror image of D-ADP

Varga A, Szabó J, Flachner B, Roy B, Konarev P, Svergun D, Závodszky P, Périgaud C, Barman T, Lionne C, Vas M

Biochemical and biophysical research communications 2008

doi:10.1016/j.bbrc.2007.12.061.

Low resolution structural models of the basic helix-loop-helix leucine zipper domain of upstream stimulatory factor 1 and its complexes with DNA from small angle X-ray scattering data

Lamber EP, Wilmanns M, Svergun DI

Biophysical journal 2008

doi:10.1529/biophysj.107.112243.

Interaction between the C-terminal region of human myelin basic protein and calmodulin: analysis of complex formation and solution structure

Majava V, Petoukhov MV, Hayashi N, Pirilä P, Svergun DI, Kursula P

BMC structural biology 2008

doi:10.1186/1472-6807-8-10.

Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin

Pinotsis N, Lange S, Perriard JC, Svergun DI, Wilmanns M

The EMBO journal 2008

doi:10.1038/sj.emboj.7601944.

Hydrophilic Monodisperse Magnetic Nanoparticles Protected by an Amphiphilic Alternating Copolymer

Shtykova EV, Huang X, Gao X, Dyke JC, Schmucker AL, Dragnea B, Remmes N, Baxter DV, Stein B, Konarev PV, Svergun DI, Bronstein LM

The journal of physical chemistry. C, Nanomaterials and interfaces 2008

doi:10.1021/jp8053636.

Solution structure of poly(ethylene) glycol-conjugated hemoglobin revealed by small-angle X-ray scattering: implications for a new oxygen therapeutic

Svergun DI, Ekström F, Vandegriff KD, Malavalli A, Baker DA, Nilsson C, Winslow RM

Biophysical journal 2008

doi:10.1529/biophysj.107.114314.

A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain

von Castelmur E, Marino M, Svergun DI, Kreplak L, Ucurum-Fotiadis Z, Konarev PV, Urzhumtsev A, Labeit D, Labeit S, Mayans O

Proceedings of the National Academy of Sciences of the United States of America 2008

doi:10.1073/pnas.0707163105.

The structure of a full-length response regulator from Mycobacterium tuberculosis in a stabilized three-dimensional domain-swapped, activated state

King-Scott J, Nowak E, Mylonas E, Panjikar S, Roessle M, Svergun DI, Tucker PA

The Journal of biological chemistry 2007

doi:10.1074/jbc.m705081200.

Analysis of X-ray and neutron scattering from biomacromolecular solutions

Petoukhov MV, Svergun DI

Current opinion in structural biology 2007

doi:10.1016/j.sbi.2007.06.009.

Crystal structure and activity of Kunjin virus NS3 helicase; protease and helicase domain assembly in the full length NS3 protein

Mastrangelo E, Milani M, Bollati M, Selisko B, Peyrane F, Pandini V, Sorrentino G, Canard B, Konarev PV, Svergun DI, de Lamballerie X, Coutard B, Khromykh AA, Bolognesi M

Journal of molecular biology 2007

doi:10.1016/j.jmb.2007.06.055.

The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans

Raczynska J, Olchowy J, Konariev PV, Svergun DI, Milewski S, Rypniewski W

Journal of molecular biology 2007

doi:10.1016/j.jmb.2007.07.002.

Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex

Tidow H, Melero R, Mylonas E, Freund SM, Grossmann JG, Carazo JM, Svergun DI, Valle M, Fersht AR

Proceedings of the National Academy of Sciences of the United States of America 2007

doi:10.1073/pnas.0705069104.

Structural characterization of flexible proteins using small-angle X-ray scattering

Bernadó P, Mylonas E, Petoukhov MV, Blackledge M, Svergun DI

Journal of the American Chemical Society 2007

doi:10.1021/ja069124n.

Crystal structure of human filamin C domain 23 and small angle scattering model for filamin C 23-24 dimer

Sjekloća L, Pudas R, Sjöblom B, Konarev P, Carugo O, Rybin V, Kiema TR, Svergun D, Ylänne J, Djinović Carugo K

Journal of molecular biology 2007

doi:10.1016/j.jmb.2007.02.018.

A helical structural nucleus is the primary elongating unit of insulin amyloid fibrils

Vestergaard B, Groenning M, Roessle M, Kastrup JS, van de Weert M, Flink JM, Frokjaer S, Gajhede M, Svergun DI

PLoS biology 2007

doi:10.1371/journal.pbio.0050134.

Molecular analysis and solution structure from small-angle X-ray scattering of the human natural killer inhibitory receptor IRp60 (CD300a)

Dimasi N, Roessle M, Moran O, Candiano G, Svergun DI, Biassoni R

International journal of biological macromolecules 2007

doi:10.1016/j.ijbiomac.2006.07.005.

Plant transformation by Agrobacterium tumefaciens: modulation of single-stranded DNA-VirE2 complex assembly by VirE1

Frenkiel-Krispin D, Wolf SG, Albeck S, Unger T, Peleg Y, Jacobovitch J, Michael Y, Daube S, Sharon M, Robinson CV, Svergun DI, Fass D, Tzfira T, Elbaum M

The Journal of biological chemistry 2007

doi:10.1074/jbc.m605270200.

Structural characterization of the ribosomal P1A-P2B protein dimer by small-angle X-ray scattering and NMR spectroscopy

Grela P, Helgstrand M, Krokowski D, Boguszewska A, Svergun D, Liljas A, Bernadó P, Grankowski N, Akke M, Tchórzewski M

Biochemistry 2007

doi:10.1021/bi0616450.

Structural characterization of beta-sheeted oligomers formed on the pathway of oxidative prion protein aggregation in vitro

Redecke L, von Bergen M, Clos J, Konarev PV, Svergun DI, Fittschen UE, Broekaert JA, Bruns O, Georgieva D, Mandelkow E, Genov N, Betzel C

Journal of structural biology 2007

doi:10.1016/j.jsb.2006.06.013.

Upgrade of the small-angle X-ray scattering beamline X33 at the European Molecular Biology Laboratory, Hamburg

Roessle MW, Klaering R, Ristau U, Robrahn B, Jahn D, Gehrmann T, Konarev P, Round A, Fiedler S, Hermes C, Svergun D

2007

doi:10.1107/S0021889806055506.

Fine-tuning of intrinsic N-Oct-3 POU domain allostery by regulatory DNA targets

Alazard R, Mourey L, Ebel C, Konarev PV, Petoukhov MV, Svergun DI, Erard M

Nucleic acids research 2007

doi:10.1093/nar/gkm453.

Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins

Németh-Pongrácz V, Barabás O, Fuxreiter M, Simon I, Pichová I, Rumlová M, Zábranská H, Svergun D, Petoukhov M, Harmat V, Klement E, Hunyadi-Gulyás E, Medzihradszky KF, Kónya E, Vértessy BG

Nucleic acids research 2007

doi:10.1093/nar/gkl1074.

ATSAS 2.1 - towards automated and web-supported small-angle scattering data analysis

Petoukhov MV, Konarev PV, Kikhney AG, Svergun DI

Journal of applied crystallography 2007

doi:.

The HC fragment of tetanus toxin forms stable, concentration-dependent dimers via an intermolecular disulphide bond

Qazi O, Bolgiano B, Crane D, Svergun DI, Konarev PV, Yao ZP, Robinson CV, Brown KA, Fairweather N

Journal of molecular biology 2007

doi:10.1016/j.jmb.2006.09.050.

Release factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies

Zoldák G, Redecke L, Svergun DI, Konarev PV, Voertler CS, Dobbek H, Sedlák E, Sprinzl M

Nucleic acids research 2007

doi:10.1093/nar/gkl696.

Structure validation of the Josephin domain of ataxin-3: conclusive evidence for an open conformation

Nicastro G, Habeck M, Masino L, Svergun DI, Pastore A

Journal of biomolecular NMR 2006

doi:10.1007/s10858-006-9092-z.

The crystal and solution structures of glyceraldehyde-3-phosphate dehydrogenase reveal different quaternary structures

Ferreira-da-Silva F, Pereira PJ, Gales L, Roessle M, Svergun DI, Moradas-Ferreira P, Damas AM

The Journal of biological chemistry 2006

doi:10.1074/jbc.m605267200.

The impact of protein characterization in structural proteomics

Geerlof A, Brown J, Coutard B, Egloff MP, Enguita FJ, Fogg MJ, Gilbert RJ, Groves MR, Haouz A, Nettleship JE, Nordlund P, Owens RJ, Ruff M, Sainsbury S, Svergun DI, Wilmanns M

Acta crystallographica. Section D, Biological crystallography 2006

doi:10.1107/s0907444906030307.

Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates

Sokolova AV, Kreplak L, Wedig T, Mücke N, Svergun DI, Herrmann H, Aebi U, Strelkov SV

Proceedings of the National Academy of Sciences of the United States of America 2006

doi:10.1073/pnas.0603629103.

CELL 51-Interactions between a human glycosylated salivary proline-rich protein and a flavan-3-ol monomer studied by SAXS

Pascal C, Vernhet A, Svergun DI, Konarev P, Zanchi D, Cabane B

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2006

doi:.

The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin

Marino M, Zou P, Svergun D, Garcia P, Edlich C, Simon B, Wilmanns M, Muhle-Goll C, Mayans O

Structure (London, England : 1993) 2006

doi:10.1016/j.str.2006.07.009.

Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2

Marx A, Nugoor C, Müller J, Panneerselvam S, Timm T, Bilang M, Mylonas E, Svergun DI, Mandelkow EM, Mandelkow E

The Journal of biological chemistry 2006

doi:10.1074/jbc.m604865200.

Joint use of small-angle X-ray and neutron scattering to study biological macromolecules in solution

Petoukhov MV, Svergun DI

European biophysics journal : EBJ 2006

doi:10.1007/s00249-006-0063-9.

Multiple assembly states of lumazine synthase: a model relating catalytic function and molecular assembly

Zhang X, Konarev PV, Petoukhov MV, Svergun DI, Xing L, Cheng RH, Haase I, Fischer M, Bacher A, Ladenstein R, Meining W

Journal of molecular biology 2006

doi:10.1016/j.jmb.2006.07.037.

Structural and functional properties of mouse proNGF

Paoletti F, Konarev PV, Covaceuszach S, Schwarz E, Cattaneo A, Lamba D, Svergun DI

BIOCHEMICAL SOCIETY TRANSACTIONS 2006

doi:10.1042/bst0340605.

Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus

Pinotsis N, Petoukhov M, Lange S, Svergun D, Zou P, Gautel M, Wilmanns M

Journal of structural biology 2006

doi:10.1016/j.jsb.2006.03.028.

Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus

Marino M, Deuss M, Svergun DI, Konarev PV, Sterner R, Mayans O

The Journal of biological chemistry 2006

doi:10.1074/jbc.m601403200.

Molecular insights into the self-assembly mechanism of dystrophia myotonica kinase

Garcia P, Ucurum Z, Bucher R, Svergun DI, Huber T, Lustig A, Konarev PV, Marino M, Mayans O

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006

doi:10.1096/fj.05-5262com.

Conformation of polypyrimidine tract binding protein in solution

Petoukhov MV, Monie TP, Allain FH, Matthews S, Curry S, Svergun DI

Structure (London, England : 1993) 2006

doi:10.1016/j.str.2006.04.005.

The C-terminal domain of the transcriptional corepressor CtBP is intrinsically unstructured

Nardini M, Svergun D, Konarev PV, Spanò S, Fasano M, Bracco C, Pesce A, Donadini A, Cericola C, Secundo F, Luini A, Corda D, Bolognesi M

Protein science : a publication of the Protein Society 2006

doi:10.1110/ps.062115406.

Substrate-induced double sided H-bond network as a means of domain closure in 3-phosphoglycerate kinase

Varga A, Flachner B, Konarev P, Gráczer E, Szabó J, Svergun D, Závodszky P, Vas M

FEBS letters 2006

doi:10.1016/j.febslet.2006.04.024.

The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis

Nowak E, Panjikar S, Konarev P, Svergun DI, Tucker PA

The Journal of biological chemistry 2006

doi:10.1074/jbc.m512004200.

Structural basis of hepatocyte growth factor/scatter factor and MET signalling

Gherardi E, Sandin S, Petoukhov MV, Finch J, Youles ME, Ofverstedt LG, Miguel RN, Blundell TL, Vande Woude GF, Skoglund U, Svergun DI

Proceedings of the National Academy of Sciences of the United States of America 2006

doi:10.1073/pnas.0509040103.

Dimerisation and an increase in active site aromatic groups as adaptations to high temperatures: X-ray solution scattering and substrate-bound crystal structures of Rhodothermus marinus endoglucanase Cel12A

Crennell SJ, Cook D, Minns A, Svergun D, Andersen RL, Nordberg Karlsson E

Journal of molecular biology 2006

doi:10.1016/j.jmb.2005.11.004.

Structural and functional aspects of the sensor histidine kinase PrrB from Mycobacterium tuberculosis

Nowak E, Panjikar S, Morth JP, Jordanova R, Svergun DI, Tucker PA

Structure (London, England : 1993) 2006

doi:10.1016/j.str.2005.10.006.

Hybrid polymer particles with a protective shell: synthesis, structure, and templating

Bronstein LM, Dixit S, Tomaszewski J, Stein B, Svergun DI, Konarev PV, Shtykova E, Werner-Zwanziger U, Dragnea B

Chemistry of materials : a publication of the American Chemical Society 2006

doi:10.1021/cm060129t.

ATSAS 2.1, a program package for small-angle scattering data analysis

Konarev PV, Petoukhov MV, Volkov VV, Svergun DI

Journal of applied crystallography 2006

doi:10.1107/S0021889806004699.

The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure

Vestergaard B, Sanyal S, Roessle M, Mora L, Buckingham RH, Kastrup JS, Gajhede M, Svergun DI, Ehrenberg M

Molecular cell 2005

doi:10.1016/j.molcel.2005.11.022.

Metalated diblock and triblock poly(ethylene oxide)-block-poly(4-vinylpyridine) copolymers: understanding of micelle and bulk structure

Bronstein LM, Sidorov SN, Zhirov V, Zhirov D, Kabachii YA, Kochev SY, Valetsky PM, Stein B, Kiseleva OI, Polyakov SN, Shtykova EV, Nikulina EV, Svergun DI, Khokhlov AR

The journal of physical chemistry. B 2005

doi:10.1021/jp053333x.

X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum

Goettig P, Brandstetter H, Groll M, Göhring W, Konarev PV, Svergun DI, Huber R, Kim JS

The Journal of biological chemistry 2005

doi:10.1074/jbc.m505030200.

Platinum nanoparticles generated in self-assembled polyoctadecylsiloxane functionalized with long-chain modifiers

Bronstein LM, Shtykova EV, Spontak RJ, Svergun DI

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2005

doi:.

Global rigid body modeling of macromolecular complexes against small-angle scattering data

Petoukhov MV, Svergun DI

Biophysical journal 2005

doi:10.1529/biophysj.105.064154.

Solution X-ray scattering evidence for agonist- and antagonist-induced modulation of cleft closure in a glutamate receptor ligand-binding domain

Madden DR, Armstrong N, Svergun D, Pérez J, Vachette P

The Journal of biological chemistry 2005

doi:10.1074/jbc.m414523200.

Triticum durum metallothionein. Isolation of the gene and structural characterization of the protein using solution scattering and molecular modeling

Bilecen K, Ozturk UH, Duru AD, Sutlu T, Petoukhov MV, Svergun DI, Koch MH, Sezerman UO, Cakmak I, Sayers Z

The Journal of biological chemistry 2005

doi:10.1074/jbc.m412984200.

Poly-Ig tandems from I-band titin share extended domain arrangements irrespective of the distinct features of their modular constituents

Marino M, Svergun DI, Kreplak L, Konarev PV, Maco B, Labeit D, Mayans O

Journal of muscle research and cell motility 2005

doi:10.1007/s10974-005-9017-6.

The spatial structure of dendritic macromolecules

Ozerin AN, Svergun DI, Volkov VV, Kuklin AI, Gordelyi VI, Islamov AK, Ozerina LA, Zavorotnyuk DS

Journal of applied crystallography 2005

doi:10.1107/S0021889805032115.

Synergistic use of synchrotron radiation techniques for biological samples in solution: a case study on protein-ligand recognition by the peroxisomal import receptor Pex5p

Stanley WA, Sokolova A, Brown A, Clarke DT, Wilmanns M, Svergun DI

Journal of synchrotron radiation 2004

doi:10.1107/s090904950402504x.

The crystal and solution structure of a putative transcriptional antiterminator from Mycobacterium tuberculosis

Morth JP, Feng V, Perry LJ, Svergun DI, Tucker PA

Structure (London, England : 1993) 2004

doi:10.1016/j.str.2004.06.018.

Structure and RNA interactions of the N-terminal RRM domains of PTB

Simpson PJ, Monie TP, Szendröi A, Davydova N, Tyzack JK, Conte MR, Read CM, Cary PD, Svergun DI, Konarev PV, Curry S, Matthews S

Structure (London, England : 1993) 2004

doi:10.1016/j.str.2004.07.008.

Multifunctional polymer colloids with ordered interior: Synthesis and properties

Bronstein LM, Linton CN, Stein BD, Dixit S, Svergun DI

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2004

doi:.

Structural analysis of the stalk subunit Vma5p of the yeast V-ATPase in solution

Armbrüster A, Svergun DI, Coskun U, Juliano S, Bailer SM, Grüber G

FEBS letters 2004

doi:10.1016/j.febslet.2004.06.029.

Structural characterization of the nonameric assembly of an Archaeal alpha-L-fucosidase by synchrotron small angle X-ray scattering

Rosano C, Zuccotti S, Cobucci-Ponzano B, Mazzone M, Rossi M, Moracci M, Petoukhov MV, Svergun DI, Bolognesi M

Biochemical and biophysical research communications 2004

doi:10.1016/j.bbrc.2004.05.149.

Platinum nanoparticles generated in functionality-enhanced reaction media based on polyoctadecylsiloxane with long-chain functional modifiers

Shtykova EV, Svergun DI, Chernyshov DM, Khotina IA, Valetsky PM, Spontak RJ, Bronstein LM

The journal of physical chemistry. B 2004

doi:10.1021/jp049336b.

Functional polymer colloids with ordered interior

Bronstein LM, Linton C, Karlinsey R, Stein B, Timofeeva GI, Svergun DI, Konarev PI, Kozin M, Tomaszewski J, Werner-Zwanziger U, Zwanziger JW

Langmuir : the ACS journal of surfaces and colloids 2004

doi:10.1021/la035951f.

Structural and functional characterization of Vma5p (subunit C) of the yeast vacuolar ATPase.

Armbruster A, Juliano S, Coskun U, Svergun DI, Borsch M, Gruber G

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 2004

doi:.

Conformational variability of nucleo-cytoplasmic transport factors

Fukuhara N, Fernandez E, Ebert J, Conti E, Svergun D

The Journal of biological chemistry 2004

doi:10.1074/jbc.m309112200.

Database for rapid protein classification based on small-angle X-ray scattering data

Sokolova AV, Volkov VV, Svergun DI

CRYSTALLOGRAPHY REPORTS 2003

doi:10.1134/1.1627438.

Functionalized polymer colloids with ordered interior

Bronstein LM, Linton CN, Karlinsey R, Svergun DI, Zwanziger JW

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2003

doi:.

Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering

Márquez JA, Smith CI, Petoukhov MV, Lo Surdo P, Mattsson PT, Knekt M, Westlund A, Scheffzek K, Saraste M, Svergun DI

The EMBO journal 2003

doi:10.1093/emboj/cdg448.

Controlled synthesis of novel metalated poly(aminohexyl)-(aminopropyl)silsesquioxane colloids

Bronstein LM, Linton CN, Karlinsey R, Ashcraft E, Stein BD, Svergun DI, Kozin M, Khotina IA, Spontak RJ, Werner-Zwanziger U, Zwanziger JW

LANGMUIR 2003

doi:10.1021/la034291b.

Quaternary structure of Azospirillum brasilense NADPH-dependent glutamate synthase in solution as revealed by synchrotron radiation x-ray scattering

Petoukhov MV, Svergun DI, Konarev PV, Ravasio S, van den Heuvel RH, Curti B, Vanoni MA

The Journal of biological chemistry 2003

doi:10.1074/jbc.m304147200.

Twists and turns: a tale of two shikimate-pathway enzymes

Brown KA, Carpenter EP, Watson KA, Coggins JR, Hawkins AR, Koch MH, Svergun DI

Biochemical Society transactions 2003

doi:10.1042/bst0310543.

Small-angle X-ray scattering reveals hollow nanostructures in iota- and kappa-carrageenan/surfactant complexes

Shtykova EV, Shtykova EV, Volkov VV, Konarev PV, Dembo AT, Makhaeva EE, Ronova IA, Khokhlov AR, Reynaers H, Svergun DI

JOURNAL OF APPLIED CRYSTALLOGRAPHY 2003

doi:10.1107/S0021889803006198.

Prototype of a database for rapid protein classification based on solution scattering data

Sokolova AV, Volkov VV, Svergun DI

JOURNAL OF APPLIED CRYSTALLOGRAPHY 2003

doi:10.1107/S0021889803000220.

The active conformation of glutamate synthase and its binding to ferredoxin

van den Heuvel RH, Svergun DI, Petoukhov MV, Coda A, Curti B, Ravasio S, Vanoni MA, Mattevi A

Journal of molecular biology 2003

doi:10.1016/s0022-2836(03)00522-9.

Low-resolution structure of immunoglobulins IgG, IgM and rheumatoid factor IgM-RF from solution X-ray scattering data

Volkov VV, Lapuk VA, Kayushina RL, Shtykova EV, Varlamova EY, Malfois M, Svergun DI

JOURNAL OF APPLIED CRYSTALLOGRAPHY 2003

doi:10.1107/S0021889803005156.

Small-angle scattering: a view on the properties, structures and structural changes of biological macromolecules in solution

Koch MH, Vachette P, Svergun DI

Quarterly reviews of biophysics 2003

doi:10.1017/s0033583503003871.

Studies on structure-function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway

Schütz A, Golbik R, Tittmann K, Svergun DI, Koch MH, Hübner G, König S

European journal of biochemistry / FEBS 2003

doi:10.1046/j.1432-1033.2003.03602.x.

Hydrolytic condensation of octadecyldimethyl (3-trimethoxysilylpropyl)ammonium chloride: Self-assembling and metallation of poly(siloxysilsesouioxanes)

Bronstein LM, Linton CN, Karlinsey R, Stein BD, Kozin MB, Svergun DI, Wemer-Zwanziger U, Zwanziger JW

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2003

doi:.

Metal nanoparticle formation in poly(aminohexyl-aminopropyl) silsesouioxane colloids

Bronstein LM, Linton CN, Karlinsey R, Ashcraft E, Stein BD, Svergun DI, Kozin MB, Zwanziger JW

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2003

doi:.

Low resolution structure determination shows procollagen C-proteinase enhancer to be an elongated multidomain glycoprotein

Bernocco S, Steiglitz BM, Svergun DI, Petoukhov MV, Ruggiero F, Ricard-Blum S, Ebel C, Geourjon C, Deleage G, Font B, Eichenberger D, Greenspan DS, Hulmes DJ

The Journal of biological chemistry 2003

doi:10.1074/jbc.m210857200.

19 A solution structure of the filarial nematode immunomodulatory protein, ES-62

Ackerman CJ, Harnett MM, Harnett W, Kelly SM, Svergun DI, Byron O

Biophysical journal 2003

doi:10.1016/s0006-3495(03)74868-1.

PRIMUS: a Windows PC-based system for small-angle scattering data analysis

Konarev PV, Volkov VV, Sokolova AV, Koch MHJ, Svergun DI

Journal of applied crystallography 2003

doi:10.1107/s0021889803012779.

Structural characterization of T-protein of the Escherichia coli glycine cleavage system by X-ray small angle scattering

Orun O, Koch MH, Kan B, Svergun DI, Petoukhov MV, Sayers Z

Cellular and molecular biology (Noisy-le-Grand, France) 2003

doi:.

New methods for domain structure determination of proteins from solution scattering data

Petoukhov MV, Svergun DI

Journal of applied crystallography 2003

doi:10.1107/S0021889803000591.

Small-angle scattering studies of biological macromolecules in solution

Svergun DI, Koch MHJ

Reports on progress in physics. Physical Society (Great Britain) 2003

doi:10.1088/0034-4885/66/10/R05.

Looking behind the beamstop: X-ray solution scattering studies of structure and conformational changes of biological macromolecules

Vachette P, Koch MH, Svergun DI

Methods in enzymology 2003

doi:10.1016/s0076-6879(03)74024-5.

Solution structures of human immunoglobulins IgG and IgM and rheumatoid factor IgM-RF

Volkov VV, Kayushina RL, Lapuk VA, Shtykova EV, Varlamova EY, Malfois M, Svergun DI

Crystallography Reports 2003

doi:10.1134/1.1541750.

Low-resolution structure of immunoglobulins IgG1, IgM and rheumatoid factor IgM-RF from solution X-ray scattering data

Volkov VV, Lapuk VA, Kayushina RL, Shtykova EV, Varlamova EY, Malfois M, Svergun DI

Journal of applied crystallography 2003

doi:.

Uniqueness of ab initio shape determination in small-angle scattering

Volkov VV, Svergun DI

Journal of applied crystallography 2003

doi:10.1107/S0021889803000268.

Solution scattering suggests cross-linking function of telethonin in the complex with titin

Zou P, Gautel M, Geerlof A, Wilmanns M, Koch MH, Svergun DI

The Journal of biological chemistry 2003

doi:10.1074/jbc.m210217200.

Addition of missing loops and domains to protein models by x-ray solution scattering

Petoukhov MV, Eady NA, Brown KA, Svergun DI

Biophysical journal 2002

doi:10.1016/s0006-3495(02)75315-0.

Advances in structure analysis using small-angle scattering in solution

Svergun DI, Koch MH

Current opinion in structural biology 2002

doi:10.1016/s0959-440x(02)00363-9.

A key structural role for active site type 3 copper ions in human ceruloplasmin

Vachette P, Dainese E, Vasyliev VB, Di Muro P, Beltramini M, Svergun DI, De Filippis V, Salvato B

The Journal of biological chemistry 2002

doi:10.1074/jbc.m207188200.

Novel poly(aminohexyl)(aminopropyl)silsesquioxane colloids and their metallation

Bronstein LM, Linton CN, Karlinsey R, Stein BD, Svergun DI, Spontak RJ, Zwanziger JW

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2002

doi:.

Structure analysis of biological macromolecules with small and medium angle x-ray and neutron scattering

Svergun DI

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2002

doi:.

Insights into signal transduction revealed by the low resolution structure of the FixJ response regulator

Birck C, Malfois M, Svergun D, Samama J

Journal of molecular biology 2002

doi:10.1016/s0022-2836(02)00651-4.

Synthesis of metal-loaded poly(aminohexyl)(aminopropyl)silsesquioxane colloids and their self-organization into dendrites

Bronstein LM, Linton C, Karlinsey R, Stein B, Svergun DI, Zwanziger JW, Spontak RJ

NANO LETTERS 2002

doi:10.1021/nl025543g.

Solution structure of bacteriophage PRD1 vertex complex

Sokolova A, Malfois M, Caldentey J, Svergun DI, Koch MH, Bamford DH, Tuma R

The Journal of biological chemistry 2001

doi:10.1074/jbc.m106848200.

Recent developments in synchrotron radiation X-ray scattering on (bio)-polymers

Koch MHJ, Svergun DI, Gabriel A, Goderis B, Unruh T

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 2001

doi:.

Small-angle X-ray scattering study of the structure of self-organized polymer matrices and formation of imbedded metal nanoparticles

Svergun DI, Shtykova EV, Kozin MB, Volkov VV, Konarev PV, Dembo AT, Shtykova EV, Bronshtein LM, Chernyshov DM, Platonova OA, Yakunin AN, Valetsky PM, Khokhlov AR

CRYSTALLOGRAPHY REPORTS 2001

doi:10.1134/1.1387124.

Conformation of the Drosophila motor protein non-claret disjunctional in solution from X-ray and neutron scattering

Svergun DI, Zaccai G, Malfois M, Wade RH, Koch MH, Kozielski F

The Journal of biological chemistry 2001

doi:10.1074/jbc.m103618200.

Determination of domain structure of proteins from X-ray solution scattering

Svergun DI, Petoukhov MV, Koch MH

Biophysical journal 2001

doi:10.1016/s0006-3495(01)76260-1.

A novel quaternary structure of the dimeric alpha-crystallin domain with chaperone-like activity

Feil IK, Malfois M, Hendle J, van Der Zandt H, Svergun DI

The Journal of biological chemistry 2001

doi:10.1074/jbc.m010856200.

Structural Insights into the A1 ATPase from the archaeon, Methanosarcina mazei Go1

Grüber G, Svergun DI, Coskun U, Lemker T, Koch MH, Schägger H, Müller V

Biochemistry 2001

doi:10.1021/bi002195t.

Metal nanoparticle formation in polyelectrolyte gels with regular microstructures

Bronstein LM, Svergun DI, Khokhlov AR

2001

doi:.

MASSHA - a graphics system for rigid-body modelling of macromolecular complexes against solution scattering data

Konarev PV, Petoukhov MV, Svergun DI

Journal of applied crystallography 2001

doi:10.1107/S0021889801006100.

The overall conformation of conventional kinesins studied by small angle X-ray and neutron scattering

Kozielski F, Svergun D, Zaccai G, Wade RH, Koch MH

The Journal of biological chemistry 2001

doi:10.1074/jbc.m007169200.

Automated matching of high- and low-resolution structural models

Kozin MB, Svergun DI

Journal of applied crystallography 2001

doi:10.1107/S0021889800014126.

Structure of free Thermus flavus 5 S rRNA at 1.3 nm resolution from synchrotron X-ray solution scattering

Funari SS, Rapp G, Perbandt M, Dierks K, Vallazza M, Betzel C, Erdmann VA, Svergun DI

The Journal of biological chemistry 2000

doi:10.1074/jbc.m004974200.

Evidence for major structural changes in the Manduca sexta midgut V1 ATPase due to redox modulation. A small angle X-ray scattering study

Grüber G, Svergun DI, Godovac-Zimmermann J, Harvey WR, Wieczorek H, Koch MH

The Journal of biological chemistry 2000

doi:10.1074/jbc.m002976200.

Solution structure and conformational changes of the Streptomyces chitin-binding protein (CHB1)

Svergun DI, Bećirević A, Schrempf H, Koch MH, Grüber G

Biochemistry 2000

doi:10.1021/bi000865p.

A map of protein-rRNA distribution in the 70 S Escherichia coli ribosome

Svergun DI, Nierhaus KH

The Journal of biological chemistry 2000

doi:10.1074/jbc.275.19.14432.

Solution structure of the E. coli 70S ribosome at 11.5 A resolution

Gabashvili IS, Agrawal RK, Spahn CM, Grassucci RA, Svergun DI, Frank J, Penczek P

Cell 2000

doi:10.1016/s0092-8674(00)80690-x.

Low resolution structure of the sigma54 transcription factor revealed by X-ray solution scattering

Svergun DI, Malfois M, Koch MH, Wigneshweraraj SR, Buck M

The Journal of biological chemistry 2000

doi:10.1074/jbc.275.6.4210.

Low-resolution structure of the proteolytic fragments of the Rapana venosa hemocyanin in solution

Dainese E, Svergun D, Beltramini M, Di Muro P, Salvato B

Archives of biochemistry and biophysics 2000

doi:10.1006/abbi.1999.1514.

Structural studies of the 30S subunit of ribosomes Thermus thermophilus by small-angle neutron and X-ray scattering

Fan LX, Svergun DI, Volkov VV, Aksenov VL, Algalarov CC, Selivanova OM, Shcherbakova IV, Koch M, Gilles R, Wiedenmann A, May R, Serdyuk IN

Journal of applied crystallography 2000

doi:10.1107/S0021889800098009.

A software system for rigid-body modelling of solution scattering data

Kozin MB, Svergun DI

Journal of applied crystallography 2000

doi:10.1107/S0021889800001382.

sasCIF: an extension of core Crystallographic Information File for SAS

Malfois M, Svergun DI

Journal of applied crystallography 2000

doi:10.1107/S0021889800001357.

Advanced solution scattering data analysis methods and their applications

Svergun DI

Journal of applied crystallography 2000

doi:10.1107/S0021889800001370.

A small angle x-ray scattering study of the droplet-cylinder transition in oil-rich sodium bis(2-ethylhexyl) sulfosuccinate microemulsions

Svergun DI, Konarev PV, Volkov VV, Koch MHJ, Sager WFC, Smeets J, Blokhuis M

The Journal of chemical physics 2000

doi:10.1063/1.481954.

Formation of metal nanoparticles in multilayered poly(octadecylsiloxane) as revealed by anomalous small-angle X-ray scattering

Svergun DI, Kozin MB, Konarev PV, Shtykova EV, Volkov VV, Chernyshov DM, Valetsky PM, Bronstein LM

Chemistry of materials : a publication of the American Chemical Society 2000

doi:10.1021/cm001103j.

Crystal versus solution structures of thiamine diphosphate-dependent enzymes

Svergun DI, Petoukhov MV, Koch MH, König S

The Journal of biological chemistry 2000

doi:10.1074/jbc.275.1.297.

Small-angle X-ray scattering study of platinum-containing hydrogel/surfactant complexes

Svergun DI, Shtykova EV, Kozin MB, Volkov VV, Dembo AT, Shtykova EV, Bronstein LM, Platonova OA, Yakunin AN, Valetsky PM

The journal of physical chemistry. B 2000

doi:10.1021/jp994425n.

Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing (vol 76, pg 2879, 1999)

Svergun DI

BIOPHYSICAL JOURNAL 1999

doi:.

Structure of a beheaded 30 S ribosomal subunit from Thermus thermophilus

Serdyuk I, Ulitin A, Kolesnikov I, Vasiliev V, Aksenov V, Zaccai G, Svergun D, Kozin M, Willumeit R

Journal of molecular biology 1999

doi:10.1006/jmbi.1999.3109.

A molecular envelope of the ligand-binding domain of a glutamate receptor in the presence and absence of agonist

Abele R, Svergun D, Keinänen K, Koch MH, Madden DR

Biochemistry 1999

doi:10.1021/bi982928y.

Nonaggregating mutant of recombinant human hexokinase I exhibits wild-type kinetics and rod-like conformations in solution

Aleshin AE, Malfois M, Liu X, Kim CS, Fromm HJ, Honzatko RB, Koch MH, Svergun DI

Biochemistry 1999

doi:10.1021/bi990523n.

Biochemical and structural characterization of recombinant copper-metallothionein from Saccharomyces cerevisiae

Sayers Z, Brouillon P, Svergun DI, Zielenkiewicz P, Koch MH

European journal of biochemistry / FEBS 1999

doi:10.1046/j.1432-1327.1999.00451.x.

Restoring low resolution structure of biological macromolecules from solution scattering using simulated annealing

Svergun DI

Biophysical journal 1999

doi:10.1016/s0006-3495(99)77443-6.

A synchrotron radiation X-ray scattering study of aqueous solutions of native DNA

Barone G, Sayers Z, Svergun D, Koch MHJ

Journal of synchrotron radiation 1999

doi:10.1107/s0909049599007463.

Structural model of the 30S subunit of a ribosome Thermus Thermophilu by small-angle scattering

Fan LX, Serdyuk IN, Gilles R, May R, Svergun DI

PROCEEDINGS OF THE INTERNATIONAL SCHOOL AND SYMPOSIUM ON SMALL ANGLE SCATTERING 1999

doi:.

Quaternary structure of V1 and F1 ATPase: significance of structural homologies and diversities

Svergun DI, Konrad S, Huss M, Koch MH, Wieczorek H, Altendorf K, Volkov VV, Grüber G

Biochemistry 1998

doi:10.1021/bi982367a.

A model of the quaternary structure of the Escherichia coli F1 ATPase from X-ray solution scattering and evidence for structural changes in the delta subunit during ATP hydrolysis

Svergun DI, Aldag I, Sieck T, Altendorf K, Koch MH, Kane DJ, Kozin MB, Grüber G

Biophysical journal 1998

doi:10.1016/s0006-3495(98)77665-9.

Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding

Macheroux P, Schönbrunn E, Svergun DI, Volkov VV, Koch MH, Bornemann S, Thorneley RN

The Biochemical journal 1998

doi:10.1042/bj3350319.

Escherichia coli SecA shape and dimensions

Shilton B, Svergun DI, Volkov VV, Koch MH, Cusack S, Economou A

FEBS letters 1998

doi:10.1016/s0014-5793(98)01141-7.

Solution structure of the ternary complex between aminoacyl-tRNA, elongation factor Tu, and guanosine triphosphate

Bilgin N, Ehrenberg M, Ebel C, Zaccai G, Sayers Z, Koch MH, Svergun DI, Barberato C, Volkov V, Nissen P, Nyborg J

Biochemistry 1998

doi:10.1021/bi9802869.

Small-angle X-ray solution-scattering studies on ligand-induced subunit interactions of the thiamine diphosphate dependent enzyme pyruvate decarboxylase from different organisms

König S, Svergun DI, Volkov VV, Feigin LA, Koch MH

Biochemistry 1998

doi:10.1021/bi972125v.

Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA)

Schönbrunn E, Svergun DI, Amrhein N, Koch MH

European journal of biochemistry / FEBS 1998

doi:10.1046/j.1432-1327.1998.2530406.x.

Protein hydration in solution: experimental observation by x-ray and neutron scattering

Svergun DI, Richard S, Koch MH, Sayers Z, Kuprin S, Zaccai G

Proceedings of the National Academy of Sciences of the United States of America 1998

doi:10.1073/pnas.95.5.2267.

Size distributions of metal nanoparticles in polyelectrolyte gels

Svergun DI, Shtykova EV, Dembo AT, Bronstein LM, Platonova OA, Yakunin AN, Valetsky PM, Khokhlov AR

The Journal of chemical physics 1998

doi:10.1063/1.477749.

A weighted rotation function

Svergun DI

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 1997

doi:10.1107/S0907444997006197.

ASSA, a program for three-dimensional rendering in solution scattering from biopolymers

Kozin MB, Volkov VV, Svergun DI

JOURNAL OF APPLIED CRYSTALLOGRAPHY 1997

doi:10.1107/S0021889897001830.

Restoring three-dimensional structure of biopolymers from solution scattering

Svergun DI

JOURNAL OF APPLIED CRYSTALLOGRAPHY 1997

doi:10.1107/S0021889897001039.

Shape determination from solution scattering of biopolymers

Svergun DI, Volkov VV, Kozin MB, Stuhrmann HB, Barberato C, Koch MHJ

JOURNAL OF APPLIED CRYSTALLOGRAPHY 1997

doi:10.1107/S0021889897001714.

Solution scattering structural analysis of the 70 S Escherichia coli ribosome by contrast variation .1. Invariants and validation of electron microscopy models

Svergun DI, Burkhardt N, Pedersen JS, Koch MHJ, Volkov VV, Kozin MB, Meerwink W, Stuhrmann HB, Diedrich G, Nierhaus KH

JOURNAL OF MOLECULAR BIOLOGY 1997

doi:10.1006/jmbi.1997.1190.

Solution scattering structural analysis of the 70 S Escherichia coli ribosome by contrast variation .2. A model of the ribosome and its RNA at 3.5 nm resolution

Svergun DI, Burkhardt N, Pedersen JS, Koch MHJ, Volkov VV, Kozin MB, Meerwink W, Stuhrmann HB, Diedrich G, Nierhaus KH

JOURNAL OF MOLECULAR BIOLOGY 1997

doi:10.1006/jmbi.1997.1191.

Architecture of the E-coli 70S ribosome

Burkhardt N, Diedrich G, Nierhaus KH, Meerwinck W, Stuhrmann HB, Pedersen JS, Koch MHJ, Volkov VV, Kozin MB, Svergun DI

PHYSICA B 1997

doi:10.1016/S0921-4526(96)00910-6.

A compact algorithm for evaluating linear prolate functions

Kozin MB, Volkov VV, Svergun DI

IEEE TRANSACTIONS ON SIGNAL PROCESSING 1997

doi:10.1109/78.564197.

Large differences are observed between the crystal and solution quaternary structures of allosteric aspartate transcarbamylase in the R state

Svergun DI, Barberato C, Koch MH, Fetler L, Vachette P

Proteins 1997

doi:10.1002/(sici)1097-0134(199701)27:1<110::aid-prot11>3.3.co;2-x.

Small-angle scattering data processing using linear prolate spheroidal functions

Kozin MB, Svergun DI

KRISTALLOGRAFIYA 1996

doi:.

New developments in direct shape determination from small-angle scattering .2. Uniqueness

Svergun DI, Volkov VV, Kozin MB, Stuhrmann HB

ACTA CRYSTALLOGRAPHICA SECTION A 1996

doi:10.1107/S0108767396000177.

Structural model of the 50S subunit of E-coli ribosomes from solution scattering

Svergun DI, Koch MHJ, Pedersen JS, Serdyuk IN

NEUTRONS IN BIOLOGY 1996

doi:.

Determination of the regularization parameter in indirect-transform methods using perceptual criteria

Svergun DI

Journal of applied crystallography 1992

doi:.


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