{"id":109,"date":"2021-04-09T10:54:34","date_gmt":"2021-04-09T10:54:34","guid":{"rendered":"https:\/\/www.embl.org\/groups\/sample-preparation-characterisation\/?page_id=109"},"modified":"2021-06-07T11:19:19","modified_gmt":"2021-06-07T11:19:19","slug":"publications","status":"publish","type":"page","link":"https:\/\/www.embl.org\/groups\/sample-preparation-characterisation\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n
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The following publications are (partly) based on experiments performed at the SPC:<\/p>\n\n\n\n

2021<\/h3>\n\n\n\n

Current Research in Structural Biology 3. 2021 Mar 5; 85-94. DOI:10.1016\/j.crstbi.2021.03.002 <\/span><\/a> Cyclohexyl-\u03b1 maltoside as a highly efficient tool for membrane protein studies<\/strong>. Missel J.W, Salutros N, Ramos Becares E, Steffen J H, Gerdt Laursen A, Struve Garcia A, Garcia-Alai <\/strong>M, Kolar C, Gourdon P, Gotfryd K.<\/p>\n\n\n\n

2020<\/h3>\n\n\n\n

Nat Commun. 2020 Mar 11;11(1):1314. DOI: 10.1038\/s41467-020-14862-4<\/a>.
Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection.<\/strong>
Anjanappa R, Garcia-Alai<\/strong> M, Kopicki JD, Lockhauserb\u00e4umer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers R.<\/p>\n\n\n\n

2019<\/h3>\n\n\n\n

Sci Immunol. 2019 Jul 19;4(37). pii: eaav0860. DOI: 10.1126\/sciimmunol.aav0860<\/a>.
High-throughput peptide-MHC complex generation and kinetic screenings of TCRs with peptide-receptive HLA-A*02:01 molecules.<\/strong>
Moritz A, Anjanappa R, Wagner C, Bunk S, Hofmann M, Pszolla G, Saikia A, Garcia-Alai<\/strong> M, Meijers R, Rammensee HG, Springer S, Maurer D.<\/p>\n\n\n\n

Sci Immunol. 2019 Jul 19;4(37). pii: eaau9039. DOI: 10.1126\/sciimmunol.aau9039<\/a>.
Empty peptide-receptive MHC class I molecules for efficient detection of antigen-specific T cells.<\/strong>
Saini SK, Tamhane T, Anjanappa R, Saikia A, Ramskov S, Donia M, Svane IM, Jakobsen SN, Garcia-Alai<\/strong> M, Zacharias M, Meijers R, Springer S, Hadrup SR.<\/p>\n\n\n\n

Sci Rep. 2019 Jul 17;9(1):10379. DOI: 10.1038\/s41598-019-46686-8<\/a>.
High-throughput stability screening for detergent-solubilized membrane proteins.<\/strong>
Kotov V, Bartels K, Veith K, Josts I, Subhramanyam UKT, G\u00fcnther C, Labahn J, Marlovits TC, Moraes I, Tidow H, L\u00f6w C, Garcia-Alai<\/strong> MM.<\/p>\n\n\n\n

Biochim Biophys Acta Mol Cell Res. 2019 Jul;1866(7):1162-1170. DOI: 10.1016\/j.bbamcr.2018.12.010<\/a>. 
Novel CaM-binding motif in its NudT9H domain contributes to temperature sensitivity of TRPM2.<\/strong>
Gattkowski E, Johnsen A, Bauche A, M\u00f6ckl F, Kulow F, Garcia Alai<\/strong> M, Rutherford TJ, Fliegert R, Tidow H.<\/p>\n\n\n\n

2018<\/h3>\n\n\n\n

Acta Crystallogr F Struct Biol Commun. 2018 Jan 1;74(Pt 1):23-30. DOI:10.1107\/S2053230X17017381<\/a>. Epub 2017 Dec 15.
Structure and stability of the Human respiratory syncytial virus M2-1<\/sub> RNA-binding core domain reveals a compact and cooperative folding unit.<\/strong>
Molina IG, Josts I, Almeida Hernandez Y, Esperante S, Salgueiro M, Garcia Alai MM, de Prat-Gay G, Tidow H.<\/p>\n\n\n\n

Nat Commun. 2018 Jan 23;9(1):328. DOI:10.1038\/s41467-017-02443-x<\/a>
Epsin and Sla2 form assemblies through phospholipid interfaces.<\/strong>
Garcia-Alai MM, Heidemann J, Skruzny M, Gieras A, Mertens HDT, Svergun DI, Kaksonen M, Uetrecht C, Meijers R.<\/p>\n\n\n\n

Structure. 2018 Feb 6;26(2):345-355.e5. doi:  10.1016\/j.str.2018.01.007<\/a>
Saposin Lipid Nanoparticles: A Highly Versatile and Modular Tool for Membrane Protein Research.<\/strong>
Flayhan A, Mertens HDT, Ural-Blimke Y, Martinez Molledo M, Svergun DI, L\u00f6w C.<\/p>\n\n\n\n

Structure. 2018 Mar 6;26(3):467-476.e4. doi: 10.1016\/j.str.2018.01.005. Epub 2018 Feb 8.
Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.<\/strong>
Martinez Molledo M, Quistgaard EM, Flayhan A, Pieprzyk J, L\u00f6w C.<\/p>\n\n\n\n

J Synchrotron Radiat. 2018 Mar 1;25(Pt 2):361-372. DOI:10.1107\/S1600577517017568<\/a>. Epub 2018 Feb 13.
Multi-channel in situ dynamic light scattering instrumentation enhancing biological small-angle X-ray scattering experiments at the PETRA III beamline P12.<\/strong>
Falke S, Dierks K, Blanchet C, Graewert M, Cipriani F, Meijers R, Svergun D, Betzel C.<\/p>\n\n\n\n

Neuron. 2018 Mar 21<\/strong>;97(6):1261-1267.e4. DOI:10.1016\/j.neuron.2018.02.010<\/a>. Epub 2018 Mar 1.
Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.<\/strong>
Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang JH, Meijers R.<\/p>\n\n\n\n

201<\/strong>7<\/h3>\n\n\n\n

Sci Rep. 2017 Mar 9<\/strong>;7:44297. DOI:10.1038\/srep44297<\/a>
High-efficient production and biophysical characterisation of nicastrin and its interaction with APPC100.<\/strong>
Yu K, Yang G, Labahn J.<\/p>\n\n\n\n

PLoS One. 2017 Mar 6;12(3):e0173126. DOI:10.1371\/journal.pone.0173126<\/a>. eCollection 2017.
Structure determination of a major facilitator peptide transporter: Inward facing PepTSt from Streptococcus thermophilus crystallized in space group P3121.<\/strong>
Quistgaard EM, Martinez Molledo M, L\u00f6w C.<\/p>\n\n\n\n

J Synchrotron Radiat. 2017 Jan 1<\/strong>;24(Pt 1):323-332. DOI:10.1107\/S1600577516016465<\/a>. Epub 2017 Jan 1.
P13, the EMBL macromolecular crystallography beamline at the low-emittance PETRA III ring for high- and low-energy phasing with variable beam focusing.<\/strong>
Cianci M, Bourenkov G, Pompidor G, Karpics I, Kallio J, Bento I, Roessle M, Cipriani F, Fiedler S, Schneider TR.<\/p>\n\n\n\n

THESIS FOR DOCTORAL DEGREE:<\/a>
Structural and functional basis of mitochondrial tRNA processing<\/strong>
Author: Sridhara, Sagar Date: 2017-12-20<\/p>\n\n\n\n

Chembiochem. 2017 Sep 5<\/strong>;18(17):1735-1742. DOI:10.1002\/cbic.201700235<\/a>. Epub 2017 Jul 17.
Lipid-like Peptides can Stabilize Integral Membrane Proteins for Biophysical and Structural Studies.<\/strong>
Veith K, Martinez Molledo M, Almeida Hernandez Y, Josts I, Nitsche J, L\u00f6w C, Tidow H.<\/p>\n\n<\/div>\n<\/div>\n\n\n

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