{"id":14,"date":"2020-06-08T10:50:51","date_gmt":"2020-06-08T10:50:51","guid":{"rendered":"https:\/\/www.embl.org\/groups\/metabolomics\/home\/"},"modified":"2026-02-25T07:16:28","modified_gmt":"2026-02-25T07:16:28","slug":"home","status":"publish","type":"page","link":"https:\/\/www.embl.org\/groups\/metabolomics\/","title":{"rendered":"Home"},"content":{"rendered":"<div class=\"vf-grid vf-grid__col-3 | vf-u-margin__bottom--800\">\n      <div class=\"vf-grid__col--span-2\">\n      <div class=\"vf-content-hub-html\">\n  <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=profiles&amp;filter-uuid=938a87ed-6b09-4519-8edc-cd475b01431a&amp;pattern=node-teaser -->\n      <div data-embl-js-conditional-edit=\"28182\">\n              <h1 class=\"vf-lede\">The facility is equipped with a high-resolution mass spectrometry system (HRMS) coupled with liquid chromatography (UHPLC) and direct infusion (NanoMate) for separation and detection of various classes of small molecules, metabolites and lipids.<\/p>\r\n\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/28182\" target=\"_blank\">Edit<\/a>\n    <\/div>\n  <\/div>\n    <\/div>\n      <div >\n\n<!-- <style>\n  .vf-content-hub-html {\n    --vf-stack-margin--custom: unset !important;\n  }\n<\/style> -->\n\n    <div class=\"vf-content-hub-html vf-stack vf-stack--600\" data-cache=\"d5c2244f\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-value%5Bfield_person_positions.entity.field_position_membership%5D=leader&amp;filter-field-value%5Bfield_person_positions.entity.field_position_team.entity.field_foreignid%5D=459&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2Cmobile%2Cphones%5D=1&amp;limit=1&amp;pattern=vf-profile-inline&amp;sort-field-value%5Bchanged%5D=DESC -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"88612\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60031476.jpg?itok=XXhmnt8h\" alt=\"image of Michael Zimmermann\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/michael-zimmermann\" class=\"vf-profile__link\">Michael Zimmermann<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Group Leader\n        <\/p>\n      \n      \n      \n      \n      \n      \n              <p class=\"vf-profile__uuid\">\n          <span>ORCID:<\/span>\n          <a class=\"vf-profile__link vf-profile__link--secondary\" href=\"https:\/\/europepmc.org\/authors\/0000-0002-5797-3589\">\n            0000-0002-5797-3589\n          <\/a>\n        <\/p>\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/88612\/88612\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n  <\/div>\n<\/div>\n\n\n\n<div class=\"embl-grid embl-grid--has-centered-content\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-section-header | vf-u-margin__bottom--400\">\n  <h2 class=\"vf-section-header__heading\" \n    >\n  Major projects and accomplishments  <\/h2>\n  <\/div>\n\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<ul class=\"wp-block-list\">\n<li>Identification and detection of various classes of small molecules, metabolites, and lipids in various biological matrices<\/li>\n\n\n\n<li><a href=\"http:\/\/curatr.mcf.embl.de\/\">EMBL-MCF mass spectral library<\/a> from over 700 metabolites &amp; <a href=\"https:\/\/www.embl.org\/groups\/metabolomics\/instrumentation-and-software\/#MCF-library\" data-type=\"URL\" data-id=\"https:\/\/www.embl.org\/groups\/metabolomics\/instrumentation-and-software\/#MCF-library\" target=\"_blank\" rel=\"noreferrer noopener\">EMBL-MCF 2.0<\/a> (LC-MS\/MS library using low-adsorption chromatopgraphy)<\/li>\n\n\n\n<li>Lipidomics profiling platform for comprehensive analysis of lipid species from multiple lipid classes (e.g. glycerols (TGs, DGs), phospholipids, ceramides, sphingomyelins, free fatty acids, cholesterylesters, etc.)<\/li>\n\n\n\n<li>Absolute quantitation of metabolites and lipids using internal standards<\/li>\n\n\n\n<li>Analysis of drugs and related metabolites<\/li>\n<\/ul>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"vf-divider\">\n\n\n\n<div class=\"embl-grid embl-grid--has-centered-content\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-section-header | vf-u-margin__bottom--400\">\n  <h2 class=\"vf-section-header__heading\" \n    >\n        <a class=\"vf-section-header__heading vf-section-header__heading--is-link\"\n            href=\"https:\/\/www.embl.org\/groups\/metabolomics\/services\/\">Services provided<svg aria-hidden=\"true\" class=\"vf-section-header__icon | vf-icon vf-icon-arrow--inline-end\" width=\"24\" height=\"24\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 12c0 6.627 5.373 12 12 12s12-5.373 12-12S18.627 0 12 0C5.376.008.008 5.376 0 12zm13.707-5.209l4.5 4.5a1 1 0 010 1.414l-4.5 4.5a1 1 0 01-1.414-1.414l2.366-2.367a.25.25 0 00-.177-.424H6a1 1 0 010-2h8.482a.25.25 0 00.177-.427l-2.366-2.368a1 1 0 011.414-1.414z\" fill=\"\" fill-rule=\"nonzero\"><\/path><\/svg><\/a>\n      <\/h2>\n  <\/div>\n\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p>We provide services for mass spectrometry-based analysis of small molecules, metabolites and lipids.<\/p>\n\n\n\n<p>We perform targeted and untargeted measurements of various classes of molecules ranging from small, polar metabolites (amino acids, nucleotides, sugars, phosphates) to lipids in a variety of biological matrices.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\">Further services<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Global untargeted metabolomics and lipidomics profiling<\/li>\n\n\n\n<li>Targeted metabolomics profiling<\/li>\n\n\n\n<li>Free fatty acid analysis<\/li>\n\n\n\n<li>Targeted PFAS analysis<\/li>\n\n\n\n<li>Metabolite and lipid identification using MS and MS\/MS analysis<\/li>\n\n\n\n<li>Drug and drug metabolite analysis<\/li>\n\n\n\n<li>Consultation of experimental study design<\/li>\n\n\n\n<li>Data processing incl. metabolite &amp; lipid identification (<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11306-007-0082-2\">level 1 confidence<\/a>), visualization, and statistical analysis<\/li>\n\n\n\n<li>Data archiving and sharing\/publishing<\/li>\n<\/ul>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"vf-divider\">\n\n\n\n<div class=\"embl-grid embl-grid--has-centered-content\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-section-header | vf-u-margin__bottom--400\">\n  <h2 class=\"vf-section-header__heading\" \n    >\n  Acknowledgment and Authorship  <\/h2>\n  <\/div>\n\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p>As per EMBL Internal Publication Policy (No. 63); if the facility services were used in&nbsp;work described in a publication, the facility must be acknowledged. For acknowledgment, the following statement must be added:<\/p>\n\n\n\n<blockquote class=\"vf-blockquote | vf-stack vf-stack--400\">\n    <p class=\"vf-blockquote__text\">We acknowledge the support of the EMBL Metabolomics Core Facility (MCF) in the acquisition and analysis of liquid chromatography-mass spectrometry data.<\/p>\n\n\n<\/blockquote>\n\n\n\n<p>In addition, if a staff member of the Metabolomics Core Facility contributes substantially to a published work, the staff member should be included as an author in the published work.<\/p>\n\n\n\n<p>More information on this topic can be found here: <a rel=\"noreferrer noopener\" href=\"https:\/\/www.abrf.org\/authorship-guidelines\" target=\"_blank\">Recommended guidelines<\/a> &amp; <a href=\"https:\/\/www.embopress.org\/doi\/full\/10.15252\/embr.202255734\" target=\"_blank\" rel=\"noreferrer noopener\">Acknowledging and citing core facilities<\/a><\/p>\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"vf-divider\">\n\n\n\n<div class=\"embl-grid embl-grid--has-centered-content\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-section-header | vf-u-margin__bottom--400\">\n  <h2 class=\"vf-section-header__heading\" \n  id=\"contact\"  >\n  Contact  <\/h2>\n  <\/div>\n\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<div class=\"vf-grid | vf-grid__col-1\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-content-hub-html\" data-cache=\"8b53cb96\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_full_name%5D=michael%20zimmermann&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5B0%5D=1&amp;limit=1&amp;pattern=vf-profile-inline -->\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"88612\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60031476.jpg?itok=XXhmnt8h\" alt=\"image of Michael Zimmermann\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/michael-zimmermann\" class=\"vf-profile__link\">Michael Zimmermann<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Group Leader\n        <\/p>\n      \n              <p class=\"vf-profile__text\">\n          Zimmermann Group\n        <\/p>\n      \n      \n      \n      \n      \n              <p class=\"vf-profile__uuid\">\n          <span>ORCID:<\/span>\n          <a class=\"vf-profile__link vf-profile__link--secondary\" href=\"https:\/\/europepmc.org\/authors\/0000-0002-5797-3589\">\n            0000-0002-5797-3589\n          <\/a>\n        <\/p>\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/88612\/88612\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<div class=\"vf-grid | vf-grid__col-1\"><div><!--[vf\/content]-->\n<div class=\"vf-content\">\n<div class=\"vf-content-hub-html vf-grid vf-grid__col-2 | vf-u-margin__bottom--800\" data-cache=\"0a929a0a\">\n      <!-- Generated by: http:\/\/content.embl.org\/api\/v1\/pattern.html?filter-content-type=person&amp;filter-field-contains%5Bfield_person_positions.entity.field_position_team.entity.title%5D=Metabolomics%20Core%20Facility&amp;filter-field-value-not%5Bfield_person_positions.entity.field_position_membership%5D=leader&amp;filter-fields-empty=field_person_visible_internally&amp;filter-ref-entity%5Bfield_person_positions%5D%5Btitle%5D=&amp;filter-ref-entity%5Bfield_person_positions%5D%5Bfield_position_primary%5D=1&amp;hide%5Bteam%2C%5D=1&amp;limit=50&amp;pattern=vf-profile-inline&amp;sort-field-value%5Bfield_person_full_name%5D=ASC -->\n                \n                      <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"184971\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/assets.emblstatic.net\/vf\/v2.4.14\/assets\/vf-summary\/assets\/vf-icon--avatar.svg\" alt=\"image of Alexander Spiegelhalter\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/alexander-spiegelhalter\" class=\"vf-profile__link\">Alexander Spiegelhalter<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Research Technician\n        <\/p>\n      \n      \n      \n      \n      \n      \n              <p class=\"vf-profile__uuid\">\n          <span>ORCID:<\/span>\n          <a class=\"vf-profile__link vf-profile__link--secondary\" href=\"https:\/\/europepmc.org\/authors\/0000-0001-9526-1067\">\n            0000-0001-9526-1067\n          <\/a>\n        <\/p>\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/184971\/184971\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"147870\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60037416.jpg?itok=CuVJskAm\" alt=\"image of Bernhard Drotleff\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/bernhard-drotleff\" class=\"vf-profile__link\">Bernhard Drotleff<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Operational Manager\n        <\/p>\n      \n      \n      \n      \n      \n      \n              <p class=\"vf-profile__uuid\">\n          <span>ORCID:<\/span>\n          <a class=\"vf-profile__link vf-profile__link--secondary\" href=\"https:\/\/europepmc.org\/authors\/0000-0003-0914-6578\">\n            0000-0003-0914-6578\n          <\/a>\n        <\/p>\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/147870\/147870\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"802989\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60040429.jpg?itok=g1pFqBtL\" alt=\"image of Elisabete Morais\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/elisabete-morais\" class=\"vf-profile__link\">Elisabete Morais<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Postdoctoral Fellow\n        <\/p>\n      \n      \n      \n      \n      \n      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/802989\/802989\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n                \n                      <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"1590961\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/assets.emblstatic.net\/vf\/v2.4.14\/assets\/vf-summary\/assets\/vf-icon--avatar.svg\" alt=\"image of Fran\u00e7ois-Xavier Lehr\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/francois-xavier-lehr\" class=\"vf-profile__link\">Fran\u00e7ois-Xavier Lehr<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Postdoctoral Fellow (ARISE2)\n        <\/p>\n      \n      \n      \n      \n      \n      \n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/1590961\/1590961\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n                \n                            <article class=\"vf-profile vf-profile--very-easy vf-profile--medium vf-profile--inline\" data-embl-js-conditional-edit=\"1444539\">\n              <img decoding=\"async\" class=\"vf-profile__image\" src=\"https:\/\/content.embl.org\/\/sites\/default\/files\/styles\/medium\/public\/persons\/CP-60100938.jpg?itok=SjTMvjVR\" alt=\"image of T\u00edmea K\u00f6rm\u00f6czi\" \/>\n      \n              <h3 class=\"vf-profile__title\">\n                      <a href=\"https:\/\/www.embl.org\/people\/person\/timea-koermoeczi\" class=\"vf-profile__link\">T\u00edmea K\u00f6rm\u00f6czi<\/a>\n                  <\/h3>\n      \n              <p class=\"vf-profile__job-title\">\n          Scientific Officer &#8211; Metabolomics Core Facility\n        <\/p>\n      \n      \n      \n      \n      \n      \n              <p class=\"vf-profile__uuid\">\n          <span>ORCID:<\/span>\n          <a class=\"vf-profile__link vf-profile__link--secondary\" href=\"https:\/\/europepmc.org\/authors\/0000-0002-0973-2473\">\n            0000-0002-0973-2473\n          <\/a>\n        <\/p>\n            <a class=\"vf-text vf-text--body-r vf-link embl-conditional-edit\" rel=\"noopener noreferrer nofollow\" href=\"\/node\/1444539\/1444539\" target=\"_blank\">\n        Edit\n      <\/a>\n    <\/article>\n  <\/div>\n\n\n\n<p><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<p><\/p>\n\n\n\n<hr class=\"vf-divider\">\n\n\n\n<a href=\"https:\/\/www.embl.org\/groups\/metabolomics\/publications\/\" target=\"_blank\">\n<button class=\"vf-button vf-button--primary vf-button--sm\">Publications<\/button>\n<\/a>\n<!--\/vf-button-->\n\n\n<\/div>\n<\/div>\n\n\n<div><!--[vf\/content]-->\n<div class=\"vf-content\">\n\n<p><strong>Metabolomics Core Facility<br><\/strong>EMBL Heidelberg, <br>Meyerhofstra\u00dfe 1, <br>69117 Heidelberg, Germany<br><br>Tel: +49 6221 387-8705<\/p>\n\n\n\n<p>E-mail:&nbsp;<a href=\"mailto:mcf@embl.de\">mcf@embl.de<\/a><\/p>\n\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"vf_template_overview.php","meta":{"_acf_changed":false,"footnotes":""},"embl_taxonomy":[],"class_list":["post-14","page","type-page","status-publish","hentry"],"acf":[],"embl_taxonomy_terms":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/pages\/14","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/comments?post=14"}],"version-history":[{"count":190,"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/pages\/14\/revisions"}],"predecessor-version":[{"id":26433,"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/pages\/14\/revisions\/26433"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/media?parent=14"}],"wp:term":[{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/metabolomics\/wp-json\/wp\/v2\/embl_taxonomy?post=14"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}