{"id":8430,"date":"2023-03-15T15:16:10","date_gmt":"2023-03-15T15:16:10","guid":{"rendered":"https:\/\/www.embl.org\/groups\/galej\/?p=8430"},"modified":"2023-03-15T15:16:11","modified_gmt":"2023-03-15T15:16:11","slug":"ints15-paper-is-out","status":"publish","type":"post","link":"https:\/\/www.embl.org\/groups\/galej\/blog\/2023\/03\/ints15-paper-is-out\/","title":{"rendered":"INTS15 paper is out"},"content":{"rendered":"\n<p>Our latest collaboration with  Sarah Offley and Alessandro <a href=\"https:\/\/wistar.org\/our-scientists\/alessandro-gardini\">Gardini group<\/a> from the Wistar Institute provides new insights into the structure and function of the previously uncharacterized protein associated with the Integrator complex. We used functional genomics to show that INTS15 is a core component of the Integrator complex and AlphaFold2 to model its association with other Integrator proteins.  <\/p>\n\n\n\n<p> <\/p>\n\n\n\n<figure class=\"vf-figure wp-block-image size-large\"><a href=\"https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(23)00255-3\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"904\" class=\"vf-figure__image\" src=\"https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-1024x904.png\" alt=\"\" class=\"wp-image-8432\" srcset=\"https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-1024x904.png 1024w, https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-300x265.png 300w, https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-768x678.png 768w, https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-1536x1356.png 1536w, https:\/\/www.embl.org\/groups\/galej\/wp-content\/uploads\/2023\/03\/Cell-Reports-2048x1808.png 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Our latest collaboration with Sarah Offley and Alessandro Gardini group from the Wistar Institute provides new insights into the structure and function of the previously uncharacterized protein associated with the Integrator complex. We used functional genomics to show that INTS15 is a core&hellip;<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2029],"tags":[],"embl_taxonomy":[],"class_list":["post-8430","post","type-post","status-publish","format-standard","hentry","category-science"],"acf":[],"embl_taxonomy_terms":[],"featured_image_src":"https:\/\/www.embl.org\/groups\/galej\/wp-includes\/images\/media\/default.svg","_links":{"self":[{"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/posts\/8430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/comments?post=8430"}],"version-history":[{"count":1,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/posts\/8430\/revisions"}],"predecessor-version":[{"id":8434,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/posts\/8430\/revisions\/8434"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/media?parent=8430"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/categories?post=8430"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/tags?post=8430"},{"taxonomy":"embl_taxonomy","embeddable":true,"href":"https:\/\/www.embl.org\/groups\/galej\/wp-json\/wp\/v2\/embl_taxonomy?post=8430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}