Computer-based activity on genomics<\/p>\n\n\n\n
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This resource has been kindly translated by EMBL Teacher Ambassadors into Italian, Serbian and Greek that can be found under the “Resource package” tab.<\/p>\n <\/div>\n<\/div> \n\n <\/div>\n\n\n\n
Genome sequencing is one of the most transformative areas of the life sciences today. It informs personalised medicine and treatment options for genetic conditions such as cystic fibrosis. In response to the growing need to educate students about DNA sequencing, its potential, and its impact, this resource uses interactive, computer-based activities to encourage hands-on learning, critical thinking, and curiosity about the real-world applications of genomics. The resource aims to bridge the gap between scientific research and classroom teaching, helping students to understand the impact of genomics on healthcare and the future of medicine.<\/p>\n<\/section>\n\n\n\n This resource is designed for secondary school teachers working with students aged 16\u201319 and is suitable for both face-to-face and online learning. It consists of four main classroom activities and one optional out-of-class preparatory activity. The full set of activities can be completed in approximately two 45-minute lessons, depending on students\u2019 prior knowledge and teaching approach.<\/p>\n\n\n\n The resource focuses on genome sequencing and its application to personalised medicine, using cystic fibrosis (CF) as a case study. Activities guide students through interpreting gel electrophoresis results, using BLAST and ClinVar to identify CFTR gene mutations, classifying these mutations, and selecting appropriate therapies based on mutation type.<\/p>\n\n\n\n Students need computers with internet access to use the BLAST and ClinVar tools. Background knowledge of DNA, genes, mutations, and protein function is recommended.<\/p>\n\n\n\n The resource includes a teacher\u2019s guide, student worksheets, fact sheets, a glossary, an answer sheet, and video tutorials. <\/p>\n\n\n\n Curriculum links are provided for A-Level, IB Biology, and AP Biology. <\/p>\n\n\n\n Moreover, two SEPE videos offer additional context on genome complexity and variation analysis.<\/p>\n<\/section>\n\n\n\n Click on the button below to access the resource file in your chosen language. <\/p>\n\n\n\n <\/p>\n\n\n\n We welcome your and your students’ feedback on the resource, so feel free to share it with us via email at emblog-ells@embl.org.<\/p>\n\n\n\nFrom DNA to therapy_ENGLISH<\/a>\n\n Computer-based activity on genomics<\/p>\n","protected":false},"featured_media":39997,"parent":0,"menu_order":0,"template":"","class_list":["post-39993","teachingbase","type-teachingbase","status-publish","has-post-thumbnail","hentry","age-group-16-19","topic-area-genome-biology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/teachingbase\/39993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/teachingbase"}],"about":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/types\/teachingbase"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media\/39997"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media?parent=39993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Overview<\/h2>\n
Resource package<\/h2>\n
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\nFrom DNA to therapy_ITALIAN<\/a>\n\n
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\nFrom DNA to therapy_SERBIAN<\/a>\n
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\nFrom DNA to therapy_GREEK<\/a>\n<\/section>\n<\/div><\/div>\n\n\n","protected":false},"excerpt":{"rendered":"