{"id":22767,"date":"2018-11-15T15:48:34","date_gmt":"2018-11-15T14:48:34","guid":{"rendered":"http:\/\/emblog.embl.de\/ells\/?post_type=insight&#038;p=22767"},"modified":"2021-06-25T08:57:32","modified_gmt":"2021-06-25T08:57:32","slug":"embl-insight-lecture-2018","status":"publish","type":"insight-lecture","link":"https:\/\/www.embl.org\/ells\/insight-lecture\/embl-insight-lecture-2018\/","title":{"rendered":"EMBL Insight Lecture 2018"},"content":{"rendered":"\n<div class=\"vf-tabs\"><ul class=\"vf-tabs__list\" data-vf-js-tabs=\"true\"><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\">Content<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\">Concepts covered<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\">Watch lecture<\/a><\/li><\/ul><div class=\"vf-tabs-content\" data-vf-js-tabs-content=\"true\">\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\"><h2>Content<\/h2>\n<p><strong>The EMBL Insight Lecture 2018&nbsp;\u201cRhythms of Life \u2013 how cellular clocks function in development and disease\u201d was be presented by Dr. Alexander Aulehla on 13 December 2018.<\/strong><\/p>\n\n\n\n<p>Cellular clocks, or oscillators, are very abundant in nature. A well-known example is the circadian day-night clock that runs with a period of about 24 hours. In this EMBL Insight Lecture, Dr. Alexander Aulehla introduces a different set of cellular clocks that operate with periods in the range of only 1-2 hours and which play important roles during embryonic development and in stem cells. These cellular clocks can, in addition, become highly coordinated between neighboring cells, which leads to very unexpected and fascinating collective cellular dynamics.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.embl.org\/people\/person\/f31f0c66103021d6f9ee0e27136103ef85d819f55e51ea060a1af73b5004899a\/\" data-type=\"URL\" data-id=\"https:\/\/www.embl.org\/people\/person\/f31f0c66103021d6f9ee0e27136103ef85d819f55e51ea060a1af73b5004899a\/\" target=\"_blank\" rel=\"noreferrer noopener\">Dr. Alexander Aulehla<\/a> explains how we use modern microscopes to make these clock rhythms visible and how we address the underlying basic rules and functions of cellular rhythms.<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\"><h2>Concepts covered<\/h2>\n<p>\u2022 Cells differentiation and gene expression<br>\u2022 The role of gene expression oscillations<br>\u2022 How do cells establish a collective rhythm?<br>\u2022 Somite segmentation clock<br>\u2022 Real time imaging of developing embryos<br>\u2022 Green Fluorescent Protein (GFP)- a revolutionary tool for biology<br>\u2022 Cellular \u201cphase waives\u201d detected in vivo<br>\u2022 Cells self-organize themselves in time and space<br>\u2022 Control of signaling oscillations using microfluidics<br>\u2022 Circadian clocks<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\"><h2>Watch lecture<\/h2>\n<p>The EMBL Insight Lecture is available via on-demand-streaming from this website. You can watch it directly in the window below. Alternatively, you can open the EMBL Insight Lecture <a rel=\"noreferrer noopener\" href=\"http:\/\/medias01-web.embl.de\/Mediasite\/Play\/3b818982bcc247cc979103ead613d0a51d\" target=\"_blank\">here<\/a>.<\/p>\n\n\n<div\n  class=\"vf-embed vf-embed--custom-ratio\"\n\n  style=\"--vf-embed-max-width: 100%;\n    --vf-embed-custom-ratio-x: 640;\n    --vf-embed-custom-ratio-y: 360;\"\n><iframe loading=\"lazy\" width=\"640\" height=\"360\" src=\"https:\/\/mediasite.embl.de\/Mediasite\/Play\/3b818982bcc247cc979103ead613d0a51d\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/div>\n<\/section>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Rhythms of Life \u2013 how cellular clocks function in development and disease&#8221; by Dr. Alexander Aulehla<\/p>\n","protected":false},"featured_media":27420,"parent":0,"menu_order":0,"template":"","class_list":["post-22767","insight-lecture","type-insight-lecture","status-publish","has-post-thumbnail","hentry","age-group-16-19","topic-area-cell-biology","topic-area-developmental-biology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture\/22767","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture"}],"about":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/types\/insight-lecture"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media\/27420"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media?parent=22767"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}