{"id":18993,"date":"2011-09-10T11:16:56","date_gmt":"2011-09-10T11:16:56","guid":{"rendered":"http:\/\/emblog.embl.de\/ells\/?post_type=insight&#038;p=18993"},"modified":"2021-06-25T08:56:07","modified_gmt":"2021-06-25T08:56:07","slug":"embl-insight-lecture-2011","status":"publish","type":"insight-lecture","link":"https:\/\/www.embl.org\/ells\/insight-lecture\/embl-insight-lecture-2011\/","title":{"rendered":"EMBL Insight Lecture 2011"},"content":{"rendered":"\n<div class=\"vf-tabs\"><ul class=\"vf-tabs__list\" data-vf-js-tabs=\"true\"><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\">Content<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\">Concepts covered<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\">Watch lecture<\/a><\/li><\/ul><div class=\"vf-tabs-content\" data-vf-js-tabs-content=\"true\">\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\"><h2>Content<\/h2>\n<p><strong>The EMBL Insight Lecture 2011 \u201cChemistry and Biology \u2013 Strong allies in the fight against cancer\u201d was presented by Dr. Maja K\u00f6hn who is leading a research group at the European Molecular Biology Laboratory (EMBL) in Heidelberg.<\/strong><\/p>\n\n\n\n<p>Maja K\u00f6hn and her group are working to design molecules that inhibit proteins involved in disease mechanisms and on understanding molecular mechanisms of such proteins. During the EMBL Insight Lecture 2011 she illustrated how her lab investigates the role of phosphatases in cancer metastasis. And she demonstrated how inhibitors of phosphatases are designed by combining molecular biology, biochemistry and synthetic chemistry approaches.<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\"><h2>Concepts covered<\/h2>\n<p>\u2022 Proteins with different functions<br>\u2022 Cell signaling\/ signal transduction<br>\u2022 Cancer biology\/ Cancer hallmarks<br>\u2022 Cancer cell signaling<br>\u2022 The process of metastasis\/ metastatic phosphatase PRL-3<br>\u2022 The concept of combinatorial chemistry<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\"><h2>Watch lecture<\/h2>\n<p>The EMBL Insight Lecture is available via on-demand-streaming from this website. You can either watch it directly in the window below. Alternatively, you can open the EMBL Insight Lecture <a rel=\"noreferrer noopener\" href=\"http:\/\/medias01-web.embl.de\/Mediasite\/Play\/78d88e458ac94715a6a12606bf1cdfc21d\" target=\"_blank\">here<\/a>.<\/p>\n\n\n<div\n  class=\"vf-embed vf-embed--custom-ratio\"\n\n  style=\"--vf-embed-max-width: 100%;\n    --vf-embed-custom-ratio-x: 640;\n    --vf-embed-custom-ratio-y: 360;\"\n><iframe loading=\"lazy\" width=\"640\" height=\"360\" src=\"https:\/\/mediasite.embl.de\/Mediasite\/Play\/78d88e458ac94715a6a12606bf1cdfc21d\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/div>\n\n\n\n<p><\/p>\n<\/section>\n<\/div><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;Chemistry and Biology &#8211; strong allies in the fight against cancer&#8221; by Dr. Maja K\u00f6hn<\/p>\n","protected":false},"featured_media":27399,"parent":0,"menu_order":0,"template":"","class_list":["post-18993","insight-lecture","type-insight-lecture","status-publish","has-post-thumbnail","hentry","age-group-16-19","topic-area-cell-biology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture\/18993","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture"}],"about":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/types\/insight-lecture"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media\/27399"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media?parent=18993"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}