{"id":18964,"date":"2013-01-31T13:55:50","date_gmt":"2013-01-31T13:55:50","guid":{"rendered":"http:\/\/emblog.embl.de\/ells\/?post_type=insight&#038;p=18964"},"modified":"2021-06-25T08:58:32","modified_gmt":"2021-06-25T08:58:32","slug":"embl-insight-lecture-2013","status":"publish","type":"insight-lecture","link":"https:\/\/www.embl.org\/ells\/insight-lecture\/embl-insight-lecture-2013\/","title":{"rendered":"EMBL Insight Lecture 2013"},"content":{"rendered":"\n<div class=\"vf-tabs\"><ul class=\"vf-tabs__list\" data-vf-js-tabs=\"true\"><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\">Content<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\">Concepts covered<\/a><\/li><li class=\"vf-tabs__item\"><a class=\"vf-tabs__link\" href=\"#vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\">Watch lecture<\/a><\/li><\/ul><div class=\"vf-tabs-content\" data-vf-js-tabs-content=\"true\">\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-3b41c274-8950-42dd-a5e0-7dae80b32564\"><h2>Content<\/h2>\n<p><strong>The EMBL Insight Lecture 2013 <strong>\u201cFrom Code to Function \u2013 Observing Protein Synthesis Through the Electron Microscope\u201d was presented by EMBL group leader <\/strong>Dr. Christiane Schaffitzel on 31<sup>st<\/sup> January 2014.<\/strong><\/p>\n\n\n\n<p class=\"has-text-align-left\">Christiane Schaffitzel and her team study the function and three-dimensional structure of ribosomes using a combination of molecular biology, biochemistry and cryo-electron microscopy. In her talk, Christiane gives an overview of the steps involved in protein synthesis and the role ribosomes play in the process. She then illustrates how her research group uses cryo-electron microscopy to study the structures of these fascinating molecules. Christiane\u2019s central research questions are: what we can learn from the make up of these fascinating molecules and how are synthesised proteins targeted to their destinations?<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-6d8f4597-8049-4a64-9a24-c70523c81c05\"><h2>Concepts covered<\/h2>\n<p><br>\u2022 The central dogma of molecular biology<br>\u2022 Protein synthesis<br>\u2022 Molecular structures of the ribosomes<br>\u2022 Ribosomal RNA as an enzyme<br>\u2022 The function of ribosome subunits\u2019 function<br>\u2022 What determines whether a protein is exported or not<br>\u2022 Principals of electron microscopy<br>\u2022 Sample preparation for cryo-electron microscopy and image analysis<\/p>\n<\/section>\n\n\n\n<section class=\"vf-tabs__section\" id=\"vf-tabs__section-493788a8-95d2-4071-a5a2-618a09c7c72d\"><h2>Watch lecture<\/h2>\n<p>The EMBL Insight Lecture is available via on-demand-streaming from this website. You can watch it directly in the window below. Alternatively, you can open the EMBL Insight Lecture <a rel=\"noreferrer noopener\" href=\"http:\/\/medias01-web.embl.de\/Mediasite\/Play\/c2097680163844b696610aa1b780ae281d\" target=\"_blank\">here<\/a>.<\/p>\n\n\n<div\n  class=\"vf-embed vf-embed--custom-ratio\"\n\n  style=\"--vf-embed-max-width: 100%;\n    --vf-embed-custom-ratio-x: 640;\n    --vf-embed-custom-ratio-y: 360;\"\n><iframe loading=\"lazy\" width=\"640\" height=\"360\" src=\"https:\/\/mediasite.embl.de\/Mediasite\/Play\/c2097680163844b696610aa1b780ae281d\" frameborder=\"0\" allow=\"accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen><\/iframe><\/div>\n<\/section>\n<\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;From Code to Function &#8211; Observing Protein Synthesis Through the Electron Microscope&#8221; by Dr. Christiane Schaffitzel<\/p>\n","protected":false},"featured_media":27405,"parent":0,"menu_order":0,"template":"","class_list":["post-18964","insight-lecture","type-insight-lecture","status-publish","has-post-thumbnail","hentry","age-group-16-19","topic-area-microscopy-imaging","topic-area-structural-computational-biology"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture\/18964","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/insight-lecture"}],"about":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/types\/insight-lecture"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media\/27405"}],"wp:attachment":[{"href":"https:\/\/www.embl.org\/ells\/wp-json\/wp\/v2\/media?parent=18964"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}