Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T

European heart journal, 2016

doi:10.1093/eurheartj/ehw333.

Mice with hepcidin-resistant ferroportin accumulate iron in the retina.

Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015

doi:10.1096/fj.15-276758.

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection

Nairz M, Ferring-Appel D, Casarrubea D, Sonnweber T, Viatte L, Schroll A, Haschka D, Fang FC, Hentze MW, Weiss G, Galy B

CELL HOST & MICROBE, 2015

doi:10.1016/j.chom.2015.06.017.

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.

Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU

Blood, 2015

doi:10.1182/blood-2014-08-595256.

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H

Cell metabolism, 2015

doi:10.1016/j.cmet.2015.01.010.

Resistance of Ferroportin to Hepcidin Binding causes Exocrine Pancreatic Failure and Fatal Iron Overload

Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze MW, Galy B, Muckenthaler MU

Cell metabolism, 2014

doi:10.1016/j.cmet.2014.07.007.

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria

Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH

The Journal of biological chemistry, 2014

doi:10.1074/jbc.m114.547778.

In Vivo Disruption Of The Hepcidin-Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload

Altamura S, Grone HJ, Kessler R, Galy B, Hentze MW, Muckenthaler MU

BLOOD, 2013

doi:10.1182/blood.V122.21.175.175.

Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function

Casarrubea D, Viatte L, Hallas T, Vasanthakumar A, Eisenstein RS, Schümann K, Hentze MW, Galy B

Journal of molecular medicine (Berlin, Germany), 2013

doi:10.1007/s00109-013-1008-2.

IRON REGULATORY PROTEINS SECURE EFFICIENT DIETARY IRON INTAKE AND DEFINE A BASAL SET POINT FOR THE REGULATION OF IRON ABSORPTION

Galy B, Ferring-Appel D, Becker C, Gretz N, Grone HJ, Schumann K, Hentze MW

AMERICAN JOURNAL OF HEMATOLOGY, 2013

doi:.

IRP-1 CONTROLS IRON METABOLISM IN FRATAXIN-DEFICIENT TISSUES

Martelli A, Schmucker S, Reutenauer L, Puy H, Galy B, Hentze M, Puccio H

AMERICAN JOURNAL OF HEMATOLOGY, 2013

doi:.

IRON REGULATORY PROTEINS MEDIATE MACROPHAGE INNATE IMMUNITY AGAINST SALMONELLA

Nairz M, Ferring-Appel D, Schroll A, Hentze MW, Weiss G, Galy B

AMERICAN JOURNAL OF HEMATOLOGY, 2013

doi:.

Iron regulatory proteins control a mucosal block to intestinal iron absorption

Galy B, Ferring-Appel D, Becker C, Gretz N, Gröne HJ, Schümann K, Hentze MW

Cell reports, 2013

doi:10.1016/j.celrep.2013.02.026.

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption

Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS

Cell metabolism, 2013

doi:10.1016/j.cmet.2013.01.007.

Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide

Styś A, Galy B, Starzyński RR, Smuda E, Drapier JC, Lipiński P, Bouton C

The Journal of biological chemistry, 2011

doi:10.1074/jbc.m111.231902.

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway

Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG

Blood, 2010

doi:10.1182/blood-2009-11-253815.

Iron regulatory proteins secure mitochondrial iron sufficiency and function

Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW

Cell metabolism, 2010

doi:10.1016/j.cmet.2010.06.007.

Two to tango: regulation of Mammalian iron metabolism

Hentze MW, Muckenthaler MU, Galy B, Camaschella C

Cell, 2010

doi:10.1016/j.cell.2010.06.028.

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation

Viatte L, Gröne HJ, Hentze MW, Galy B

Journal of molecular medicine (Berlin, Germany), 2009

doi:10.1007/s00109-009-0494-8.

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism

Ferring-Appel D, Hentze MW, Galy B

Blood, 2009

doi:10.1182/blood-2008-05-155093.

Hfe acts in hepatocytes to prevent hemochromatosis

Vujić Spasić M, Kiss J, Herrmann T, Galy B, Martinache S, Stolte J, Gröne HJ, Stremmel W, Hentze MW, Muckenthaler MU

Cell metabolism, 2008

doi:10.1016/j.cmet.2007.11.014.

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum

Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW

Cell metabolism, 2008

doi:10.1016/j.cmet.2007.10.006.

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network

Muckenthaler MU, Galy B, Hentze MW

Annual review of nutrition, 2008

doi:10.1146/annurev.nutr.28.061807.155521.

Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency

Sanchez M, Galy B, Muckenthaler MU, Hentze MW

Nature structural & molecular biology, 2007

doi:10.1038/nsmb1222.

Physiologic systemic iron metabolism in mice deficient for duodenal Hfe

Vujic Spasic M, Kiss J, Herrmann T, Kessler R, Stolte J, Galy B, Rathkolb B, Wolf E, Stremmel W, Hentze MW, Muckenthaler MU

Blood, 2007

doi:10.1182/blood-2006-07-036186.

Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays

Sanchez M, Galy B, Hentze MW, Muckenthaler MU

Nature protocols, 2007

doi:10.1038/nprot.2007.293.

Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse

Galy B, Hölter SM, Klopstock T, Ferring D, Becker L, Kaden S, Wurst W, Gröne HJ, Hentze MW

Nature genetics, 2006

doi:10.1038/ng0906-967.

Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy

Sanchez M, Galy B, Dandekar T, Bengert P, Vainshtein Y, Stolte J, Muckenthaler MU, Hentze MW

The Journal of biological chemistry, 2006

doi:10.1074/jbc.m603876200.

IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice

Corna G, Galy B, Hentze MW, Cairo G

Journal of molecular medicine (Berlin, Germany), 2006

doi:10.1007/s00109-006-0068-y.

Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes

Galy B, Ferring D, Hentze MW

Genesis (New York, N.Y. : 2000), 2005

doi:10.1002/gene.20169.

Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2)

Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, Schümann K, Hentze MW

Blood, 2005

doi:10.1182/blood-2005-04-1365.

Enhancement of IRES-mediated translation of the c-myc and BiP mRNAs by the poly(A) tail is independent of intact eIF4G and PABP

Thoma C, Bergamini G, Galy B, Hundsdoerfer P, Hentze MW

Molecular cell, 2004

doi:10.1016/j.molcel.2004.08.021.

Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo

Galy B, Ferring D, Benesova M, Benes V, Hentze MW

RNA (New York, N.Y.), 2004

doi:10.1261/rna.7220704.

Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity

Wang J, Chen G, Muckenthaler M, Galy B, Hentze MW, Pantopoulos K

Molecular and cellular biology, 2004

doi:10.1128/mcb.24.3.954-965.2004.

Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites

Vagner S, Galy B, Pyronnet S

EMBO reports, 2001

doi:10.1093/embo-reports/kve208.