Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex.

Dubiez E, Pellegrini E, Finderup Brask M, Garland W, Foucher AE, Huard K, Heick Jensen T, Cusack S, Kadlec J

Cell reports, 2024

doi:10.1016/j.celrep.2023.113639.

Structure shows that the BIR2 domain of E3 ligase XIAP binds across the RIPK2 kinase dimer interface.

Lethier M, Huard K, Hons M, Favier A, Brutscher B, Boeri Erba E, Abbott DW, Cusack S, Pellegrini E

Life science alliance, 2023

doi:10.26508/lsa.202201784.

Structure of a human cap-dependent 48S translation pre-initiation complex.

Eliseev B, Yeramala L, Leitner A, Karuppasamy M, Raimondeau E, Huard K, Alkalaeva E, Aebersold R, Schaffitzel C

Nucleic acids research, 2018

doi:10.1093/nar/gky054.

Dual function of UPF3B in early and late translation termination.

Neu-Yilik G, Raimondeau E, Eliseev B, Yeramala L, Amthor B, Deniaud A, Huard K, Kerschgens K, Hentze MW, Schaffitzel C, Kulozik AE

The EMBO journal, 2017

doi:10.15252/embj.201797079.

A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation

Deniaud A, Karuppasamy M, Bock T, Masiulis S, Huard K, Garzoni F, Kerschgens K, Hentze MW, Kulozik AE, Beck M, Neu-Yilik G, Schaffitzel C

2015

doi:10.1093/nar/gkv668.

Ribosome-SRP-FtsY cotranslational targeting complex in the closed state.

von Loeffelholz O, Jiang Q, Ariosa A, Karuppasamy M, Huard K, Berger I, Shan SO, Schaffitzel C

Proceedings of the National Academy of Sciences of the United States of America, 2015

doi:10.1073/pnas.1424453112.

Membrane protein insertion and proton-motive-force-dependent secretion through the bacterial holo-translocon SecYEG-SecDF-YajC-YidC

Schulze RJ, Komar J, Botte M, Allen WJ, Whitehouse S, Gold VA, Lycklama A Nijeholt JA, Huard K, Berger I, Schaffitzel C, Collinson I

Proceedings of the National Academy of Sciences of the United States of America, 2014

doi:10.1073/pnas.1315901111.

Structural basis of signal sequence surveillance and selection by the SRP-FtsY complex

von Loeffelholz O, Knoops K, Ariosa A, Zhang X, Karuppasamy M, Huard K, Schoehn G, Berger I, Shan SO, Schaffitzel C

Nature structural & molecular biology, 2013

doi:10.1038/nsmb.2546.