Functional analysis of structural variants in single cells using Strand-seq.

Jeong H, Grimes K, Rauwolf KK, Bruch PM, Rausch T, Hasenfeld P, Benito E, Roider T, Sabarinathan R, Porubsky D, Herbst SA, Erarslan-Uysal B, Jann JC, Marschall T, Nowak D, Bourquin JP, Kulozik AE, Dietrich S, Bornhauser B, Sanders AD, Korbel JO

Nature biotechnology, 2022

doi:10.1038/s41587-022-01551-4.

Recurrent inversion polymorphisms in humans associate with genetic instability and genomic disorders.

Porubsky D, Höps W, Ashraf H, Hsieh P, Rodriguez-Martin B, Yilmaz F, Ebler J, Hallast P, Maria Maggiolini FA, Harvey WT, Henning B, Audano PA, Gordon DS, Ebert P, Hasenfeld P, Benito E, Zhu Q, Human Genome Structural Variation Consortium (HGSVC), Lee C, Antonacci F, Steinrücken M, Beck CR, Sanders AD, Marschall T, Eichler EE, Korbel JO

Cell, 2022

doi:10.1016/j.cell.2022.04.017.

Microglial corpse clearance: lessons from macrophages.

Marquez-Ropero M, Benito E, Plaza-Zabala A, Sierra A

FRONTIERS IN IMMUNOLOGY, 2020

doi:10.3389/fimmu.2020.00506.

TIP60/KAT5 is required for neuronal viability in hippocampal CA1.

Urban I, Kerimoglu C, Sakib MS, Wang HF, Benito E, Thaller C, Zhou XL, Yan J, Fischer A, Eichele G

SCIENTIFIC REPORTS, 2019

doi:10.1038/s41598-019-50927-1.

Translocator protein ligand protects against neurodegeneration in the MPTP mouse model of parkinsonism.

Gong J, Szego EM, Leonov A, Benito E, Becker S, Fischer A, Zweckstetter M, Outeiro T, Schneider A

JOURNAL OF NEUROSCIENCE, 2019

doi:10.1523/JNEUROSCI.2070-18.2019.

Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting.

Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, Heukamp A, Rannio S, Martens H, Barth J, Burk K, Wang YT, Fischer A, Dean C

SCIENCE, 2019

doi:10.1126/science.aav1483.

RNA-dependent intergenerational inheritance of enhanced synaptic plasticity after environmental enrichment.

Benito E, Kerimoglu C, Ramachandran B, Pena-Centeno T, Jain G, Stilling RM, Islam MR, Capece V, Zhou QH, Edbauer D, Dean C, Fischer A

CELL REPORTS, 2018

doi:10.1016/j.celrep.2018.03.059.

Regulation of dendritic spine morphology in hippocampal neurons by Copine-6.

Burk K, Ramachandran B, Ahmed S, Hurtado-Zavala JI, Awasthi A, Benito E, Faram R, Ahmad H, Swaminathan A, McIlhinney J, Fischer A, Perestenko P, Dean C

CEREBRAL CORTEX, 2018

doi:10.1093/cercor/bhx009.

Loss of Kdm5c causes spurious transcription and prevents the fine-tuning of activity-regulated enhancers in neurons.

Scandaglia M, Lopez-Atalaya JP, Medrano-Fernandez A, Lopez-Cascales MT, del Blanco B, Lipinski M, Benito E, Olivares R, Iwase S, Shi Y, Barco A

CELL REPORTS, 2017

doi:10.1016/j.celrep.2017.09.014.

Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.

Agis-Balboa RC, Pinheiro PS, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, Pape JC, Binder EB, Mulle C, Fischer A, Sananbenesi F

EMBO JOURNAL, 2017

doi:10.15252/embj.201796821.

KMT2A and KMT2B mediate memory function by affecting distinct genomic regions.

Kerimoglu C, Sakib MS, Jain G, Benito E, Burkhardt S, Capece V, Kaurani L, Halder R, Agis-Balboa RC, Stilling R, Urbanke H, Kranz A, Stewart AF, Fischer A

CELL REPORTS, 2017

doi:10.1016/j.celrep.2017.06.072.

HDAC1 links early life stress to schizophrenia-like phenotypes.

Bahari-Javan S, Varbanov H, Halder R, Benito E, Kaurani L, Burkhardt S, Anderson-Schmidt H, Anghelescu I, Budde M, Stilling RM, Costa J, Medina J, Dietrich DE, Figge C, Folkerts H, Gade K, Heilbronner U, Koller M, Konrad C, Nussbeck SY, Scherk H, Spitzer C, Stierl S, Stockel J, Thiel A, von Hagen M, Zimmermann J, Zitzelsberger A, Schulz S, Schmitt A, Delalle I, Falkai P, Schulze TG, Dityatev A, Sananbenesi F, Fischer A

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017

doi:10.1073/pnas.1613842114.

DNA methylation changes in plasticity genes accompany the formation and maintenance of memory

Halder R, Hennion M, Vidal RO, Shomroni O, Rahman RU, Rajput A, Centeno TP, van Bebber F, Capece V, Vizcaino JCG, Schuetz AL, Burkhardt S, Benito E, Sala MN, Javan SB, Haass C, Schmid B, Fischer A, Bonn S

NATURE NEUROSCIENCE, 2016

doi:10.1038/nn.4194.

Fine-tuned SRF activity controls asymmetrical neuronal outgrowth: implications for cortical migration, neural tissue lamination and circuit assembly.

Scandaglia M, Benito E, Morenilla-Palao C, Fiorenza A, del Blanco B, Coca Y, Herrera E, Barco A

SCIENTIFIC REPORTS, 2015

doi:10.1038/srep17470.

HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models.

Benito E, Urbanke H, Ramachandran B, Barth J, Halder R, Awasthi A, Jain G, Capece V, Burkhardt S, Navarro-Sala M, Nagarajan S, Schütz AL, Johnsen SA, Bonn S, Lührmann R, Dean C, Fischer A

The Journal of clinical investigation, 2015

doi:10.1172/JCI79942.

H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription.

Nagarajan S, Benito E, Fischer A, Johnsen SA

ONCOTARGET, 2015

doi:10.18632/oncotarget.3439.

The neuronal activity-driven transcriptome.

Benito E, Barco A

Molecular Neurobiology, 2015

doi:10.1007/s12035-014-8772-z.

De-regulation of gene expression and alternative splicing affects distinct cellular pathways in the aging hippocampus

Stilling RM, Benito E, Gertig M, Barth J, Capece V, Burkhardt S, Bonn S, Fischer A

FRONTIERS IN CELLULAR NEUROSCIENCE, 2014

doi:10.3389/fncel.2014.00373.

K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.

Stilling RM, Ronicke R, Benito E, Urbanke H, Capece V, Burkhardt S, Bahari-Javan S, Barth J, Sananbenesi F, Schutz AL, Dyczkowski J, Martinez-Hernandez A, Kerimoglu C, Dent SYR, Bonn S, Reymann KG, Fischer A

EMBO JOURNAL, 2014

doi:10.15252/embj.201487870.