IHMCIF: an extension of the PDBx/mmCIF data standard for integrative structure determination methods.

Vallat B, Webb BM, Westbrook JD, Goddard TD, Hanke CA, Graziadei A, Peisach E, Zalevsky A, Sagendorf J, Tangmunarunkit H, Voinea S, Sekharan M, Yu J, A M J J Bonvin A, DiMaio F, Hummer G, Meiler J, Tajkhorshid E, Ferrin TE, Lawson CL, Leitner A, Rappsilber J, Seidel CAM, Jeffries CM, Burley SK, Hoch JC, Kurisu G, Morris K, Patwardhan A, Velankar S, Schwede T, Trewhella J, Kesselman C, Berman HM, Sali A

Journal of molecular biology, 2024

doi:10.1016/j.jmb.2024.168546.

Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS).

Blanchet CE, Round A, Mertens HDT, Ayyer K, Graewert M, Awel S, Franke D, Dörner K, Bajt S, Bean R, Custódio TF, de Wijn R, Juncheng E, Henkel A, Gruzinov A, Jeffries CM, Kim Y, Kirkwood H, Kloos M, Knoška J, Koliyadu J, Letrun R, Löw C, Makroczyova J, Mall A, Meijers R, Pena Murillo GE, Oberthür D, Round E, Seuring C, Sikorski M, Vagovic P, Valerio J, Wollweber T, Zhuang Y, Schulz J, Haas H, Chapman HN, Mancuso AP, Svergun D

Communications biology, 2023

doi:10.1038/s42003-023-05416-7.

Small conformational changes in IgG1 detected as acidic charge variants by cation exchange chromatography.

Fukuda M, Graewert MA, Jeffries CM, Svergun DI, Yamazaki T, Koga A, Yamanaka Y

Analytical biochemistry, 2023

doi:10.1016/j.ab.2023.115302.

Crosstalk between regulatory elements in disordered TRPV4 N-terminus modulates lipid-dependent channel activity.

Goretzki B, Wiedemann C, McCray BA, Schäfer SL, Jansen J, Tebbe F, Mitrovic SA, Nöth J, Cabezudo AC, Donohue JK, Jeffries CM, Steinchen W, Stengel F, Sumner CJ, Hummer G, Hellmich UA

Nature communications, 2023

doi:10.1038/s41467-023-39808-4.

Minimum information guidelines for experiments structurally characterizing intrinsically disordered protein regions.

Mészáros B, Hatos A, Palopoli N, Quaglia F, Salladini E, Van Roey K, Arthanari H, Dosztányi Z, Felli IC, Fischer PD, Hoch JC, Jeffries CM, Longhi S, Maiani E, Orchard S, Pancsa R, Papaleo E, Pierattelli R, Piovesan D, Pritisanac I, Tenorio L, Viennet T, Tompa P, Vranken W, Tosatto SCE, Davey NE

Nature methods, 2023

doi:10.1038/s41592-023-01915-x.

The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.

Korn SM, Dhamotharan K, Jeffries CM, Schlundt A

Nature communications, 2023

doi:10.1038/s41467-023-38882-y.

X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1.

Guédez G, Loers G, Jeffries CM, Kozak S, Meijers R, Svergun DI, Schachner M, Löw C

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023

doi:10.1096/fj.202201511R.

Conformational multiplicity of bacterial ferric binding protein revealed by small angle x-ray scattering and molecular dynamics calculations.

Liu G, Ekmen E, Jalalypour F, Mertens HDT, Jeffries CM, Svergun D, Atilgan AR, Atilgan C, Sayers Z

The Journal of chemical physics, 2023

doi:10.1063/5.0136558.

2023 update of template tables for reporting biomolecular structural modelling of small-angle scattering data.

Trewhella J, Jeffries CM, Whitten AE

Acta crystallographica. Section D, Structural biology, 2023

doi:10.1107/s2059798322012141.

Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase.

Bürgi J, Lill P, Giannopoulou EA, Jeffries CM, Chojnowski G, Raunser S, Gatsogiannis C, Wilmanns M

Biological chemistry, 2023

doi:10.1515/hsz-2022-0273.

Determinants of receptor tyrosine phosphatase homophilic adhesion: structural comparison of PTPRK and PTPRM extracellular domains.

Hay IM, Shamin M, Caroe ER, Mohammed ASA, Svergun DI, Jeffries CM, Graham SC, Sharpe HJ, Deane JE

The Journal of biological chemistry, 2022

doi:10.1016/j.jbc.2022.102750.

Data analysis and modeling of small-angle neutron scattering data with contrast variation from bio-macromolecular complexes.

Whitten AE, Jeffries CM

Methods in enzymology, 2022

doi:10.1016/bs.mie.2022.09.015.

Structure and dynamics of the von Willebrand Factor C6 domain.

Chen PC, Kutzki F, Mojzisch A, Simon B, Xu ER, Aponte-Santamaría C, Horny K, Jeffries C, Schneppenheim R, Wilmanns M, Brehm MA, Gräter F, Hennig J

Journal of structural biology, 2022

doi:10.1016/j.jsb.2022.107923.

Production and characterisation of modularly deuterated UBE2D1-Ub conjugate by small angle neutron and X-ray scattering.

Pietras Z, Duff AP, Morad V, Wood K, Jeffries CM, Sunnerhagen M

European biophysics journal : EBJ, 2022

doi:10.1007/s00249-022-01620-1.

Intrinsically disordered plant protein PARCL co-localizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD.

Ostendorp A, Ostendorp S, Zhou Y, Chaudron Z, Wolffram L, Rombi K, von Pein L, Falke S, Jeffries CM, Svergun DI, Betzel C, Morris RJ, Kragler F, Kehr J

The Journal of biological chemistry, 2022

doi:10.1016/j.jbc.2022.102631.

A round-robin approach provides a detailed assessment of biomolecular small-angle scattering data reproducibility and yields consensus curves for benchmarking.

Trewhella J, Vachette P, Bierma J, Blanchet C, Brookes E, Chakravarthy S, Chatzimagas L, Cleveland TE, Cowieson N, Crossett B, Duff AP, Franke D, Gabel F, Gillilan RE, Graewert M, Grishaev A, Guss JM, Hammel M, Hopkins J, Huang Q, Hub JS, Hura GL, Irving TC, Jeffries CM, Jeong C, Kirby N, Krueger S, Martel A, Matsui T, Li N, Pérez J, Porcar L, Prangé T, Rajkovic I, Rocco M, Rosenberg DJ, Ryan TM, Seifert S, Sekiguchi H, Svergun D, Teixeira S, Thureau A, Weiss TM, Whitten AE, Wood K, Zuo X

Acta crystallographica. Section D, Structural biology, 2022

doi:10.1107/s2059798322009184.

Herpes simplex virus 1 protein pUL21 alters ceramide metabolism by activating the inter-organelle transport protein CERT.

Benedyk TH, Connor V, Caroe ER, Shamin M, Svergun DI, Deane JE, Jeffries CM, Crump CM, Graham SC

The Journal of biological chemistry, 2022

doi:10.1016/j.jbc.2022.102589.

Substrate induced movement of the metal cofactor between active and resting state.

Marsden SR, Wijma HJ, Mohr MKF, Justo I, Hagedoorn PL, Laustsen J, Jeffries CM, Svergun D, Mestrom L, McMillan DGG, Bento I, Hanefeld U

Angewandte Chemie (International ed. in English), 2022

doi:10.1002/anie.202213338.

Technical considerations for small-angle neutron scattering from biological macromolecules in solution: Cross sections, contrasts, instrument setup and measurement.

Pietras Z, Wood K, Whitten AE, Jeffries CM

Methods in enzymology, 2022

doi:10.1016/bs.mie.2022.08.008.

Recombinant AcnB, NrdR and RibD of Acinetobacter baumannii and their potential interaction with DNA adenine methyltransferase AamA.

Weber K, Doellinger J, Jeffries CM, Wilharm G

Protein expression and purification, 2022

doi:10.1016/j.pep.2022.106134.

EFAMIX, a tool to decompose inline chromatography SAXS data from partially overlapping components.

Konarev PV, Graewert MA, Jeffries CM, Fukuda M, Cheremnykh TA, Volkov VV, Svergun DI

Protein science : a publication of the Protein Society, 2021

doi:10.1002/pro.4237.

Small-angle X-ray and neutron scattering.

Jeffries CM, Ilavsky J, Martel A, Hinrichs S, Meyer A, Pedersen JS, Sokolova AV, Svergun DI

Nature reviews. Methods primers, 2021

doi:10.1038/s43586-021-00064-9.

pUL21 is a viral phosphatase adaptor that promotes herpes simplex virus replication and spread.

Benedyk TH, Muenzner J, Connor V, Han Y, Brown K, Wijesinghe KJ, Zhuang Y, Colaco S, Stoll GA, Tutt OS, Svobodova S, Svergun DI, Bryant NA, Deane JE, Firth AE, Jeffries CM, Crump CM, Graham SC

PLoS pathogens, 2021

doi:10.1371/journal.ppat.1009824.

Correction for Shtykova et al., "Solution Structure, Self-Assembly, and Membrane Interactions of the Matrix Protein from Newcastle Disease Virus at Neutral and Acidic pH".

Shtykova EV, Petoukhov MV, Dadinova LA, Fedorova NV, Tashkin VY, Timofeeva TA, Ksenofontov AL, Loshkarev NA, Baratova LA, Jeffries CM, Svergun DI, Batishchev OV

Journal of virology, 2021

doi:10.1128/JVI.00580-21.

ASAXS measurements on ferritin and apoferritin at the bioSAXS beamline P12 (PETRA III, DESY).

Wieland DCF, Schroer MA, Gruzinov AY, Blanchet CE, Jeffries CM, Svergun DI

Journal of applied crystallography, 2021

doi:10.1107/S1600576721003034.

Order from disorder in the sarcomere: FATZ forms a fuzzy but tight complex and phase-separated condensates with α-actinin.

Sponga A, Arolas JL, Schwarz TC, Jeffries CM, Rodriguez Chamorro A, Kostan J, Ghisleni A, Drepper F, Polyansky A, De Almeida Ribeiro E, Pedron M, Zawadzka-Kazimierczuk A, Mlynek G, Peterbauer T, Doto P, Schreiner C, Hollerl E, Mateos B, Geist L, Faulkner G, Kozminski W, Svergun DI, Warscheid B, Zagrovic B, Gautel M, Konrat R, Djinović-Carugo K

Science advances, 2021

doi:10.1126/sciadv.abg7653.

Comment on the optimal parameters to derive intrinsically disordered protein conformational ensembles from small-angle X-ray scattering data using the ensemble optimization method.

Sagar A, Jeffries CM, Petoukhov MV, Svergun DI, Bernadó P

Journal of chemical theory and computation, 2021

doi:10.1021/acs.jctc.1c00014.

ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis.

Manalastas-Cantos K, Konarev PV, Hajizadeh NR, Kikhney AG, Petoukhov MV, Molodenskiy DS, Panjkovich A, Mertens HDT, Gruzinov A, Borges C, Jeffries CM, Svergun DI, Franke D

Journal of applied crystallography, 2021

doi:10.1107/S1600576720013412.

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.

Custódio TF, Das H, Sheward DJ, Hanke L, Pazicky S, Pieprzyk J, Sorgenfrei M, Schroer MA, Gruzinov AY, Jeffries CM, Graewert MA, Svergun DI, Dobrev N, Remans K, Seeger MA, McInerney GM, Murrell B, Hällberg BM, Löw C

Nature communications, 2020

doi:10.1038/s41467-020-19204-y.

Adding size exclusion chromatography (SEC) and light scattering (LS) devices to obtain high-quality small angle X-ray scattering (SAXS) data.

Graewert MA, Da Vela S, Gräwert TW, Molodenskiy DS, Blanchet CE, Svergun DI, Jeffries CM

Crystals, 2020

doi:10.3390/cryst10110975.

Rapid screening of in cellulo grown protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach.

Lahey-Rudolph JM, Schönherr R, Jeffries CM, Blanchet CE, Boger J, Ferreira Ramos AS, Riekehr WM, Triandafillidis DP, Valmas A, Margiolaki I, Svergun D, Redecke L

Journal of applied crystallography, 2020

doi:10.1107/S1600576720010687.

Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.

Osz J, McEwen AG, Bourguet M, Przybilla F, Peluso-Iltis C, Poussin-Courmontagne P, Mély Y, Cianférani S, Jeffries CM, Svergun DI, Rochel N

Nucleic acids research, 2020

doi:10.1093/nar/gkaa697.

RovC - a novel type of hexameric transcriptional activator promoting type VI secretion gene expression.

Knittel V, Sadana P, Seekircher S, Stolle AS, Körner B, Volk M, Jeffries CM, Svergun DI, Heroven AK, Scrima A, Dersch P

PLoS pathogens, 2020

doi:10.1371/journal.ppat.1008552.

Anomeric selectivity of trehalose transferase with rare L-sugars.

Mestrom L, Marsden SR, van der Eijk H, Laustsen JU, Jeffries CM, Svergun DI, Hagedoorn PL, Bento I, Hanefeld U

ACS catalysis, 2020

doi:10.1021/acscatal.0c02117.

Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations.

Solomon-Degefa H, Gebauer JM, Jeffries CM, Freiburg CD, Meckelburg P, Bird LE, Baumann U, Svergun DI, Owens RJ, Werner JM, Behrmann E, Paulsson M, Wagener R

Journal of Biological Chemistry, 2020

doi:10.1074/jbc.RA120.014865.

The basics of small-angle neutron scattering (SANS for new users of structural biology).

Jeffries CM, Pietras Z, Svergun DI

EPJ Web of Conferences, 2020

doi:10.1051/epjconf/202023603001.

Structure-based identification and functional characterization of a lipocalin in the malaria parasite Plasmodium falciparum.

Burda PC, Crosskey T, Lauk K, Zurborg A, Söhnchen C, Liffner B, Wilcke L, Pietsch E, Strauss J, Jeffries CM, Svergun DI, Wilson DW, Wilmanns M, Gilberger TW

Cell reports, 2020

doi:10.1016/j.celrep.2020.107817.

Hydration in aqueous osmolyte solutions: the case of TMAO and urea.

Sahle CJ, Schroer MA, Niskanen J, Elbers M, Jeffries CM, Sternemann C

Physical chemistry chemical physics : PCCP, 2020

doi:10.1039/c9cp06785j.

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.

Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC

eLife, 2020

doi:10.7554/eLife.53789.

Tetrameric structures of inorganic CBS-pyrophosphatases from various bacterial species revealed by small-angle X-ray scattering in solution.

Dadinova LA, Soshinskaia EY, Jeffries CM, Svergun DI, Shtykova EV

Biomolecules, 2020

doi:10.3390/biom10040564.

SASBDB: towards automatically curated and validated repository for biological scattering data.

Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI

Protein science : a publication of the Protein Society, 2019

doi:10.1002/pro.3731.

An intrinsically disordered proteins community for ELIXIR.

Davey NE, Babu MM, Blackledge M, Bridge A, Capella-Gutierrez S, Dosztanyi Z, Drysdale R, Edwards RJ, Elofsson A, Felli IC, Gibson TJ, Gutmanas A, Hancock JM, Harrow J, Higgins D, Jeffries CM, Le Mercier P, Mészáros B, Necci M, Notredame C, Orchard S, Ouzounis CA, Pancsa R, Papaleo E, Pierattelli R, Piovesan D, Promponas VJ, Ruch P, Rustici G, Romero P, Sarntivijai S, Saunders G, Schuler B, Sharan M, Shields DC, Sussman JL, Tedds JA, Tompa P, Turewicz M, Vondrasek J, Vranken WF, Wallace BA, Wichapong K, Tosatto SCE.

F1000Res , 2019

doi:10.12688/f1000research.20136.1.

The dimeric ectodomain of the alkali-sensing insulin receptor-related receptor (ectoIRR) has a drop-like shape.

Shtykova EV, Petoukhov MV, Mozhaev AA, Deyev IE, Dadinova LA, Loshkarev NA, Goryashchenko AS, Bocharov EV, Jeffries CM, Svergun DI, Batishchev OV, Petrenko AG

The Journal of biological chemistry, 2019

doi:10.1074/jbc.RA119.010390.

The quaternary structure of insulin glargine and glulisine under formulation conditions.

Nagel N, Graewert MA, Gao M, Heyse W, Jeffries CM, Svergun D, Berchtold, H.

Biophysical Chemistry, 2019

doi:10.1016/j.bpc.2019.106226.

Solution structure, self-assembly and membrane interactions of the matrix protein from Newcastle disease virus at neutral and acidic pH.

Shtykova EV, Petoukhov MV, Dadinova LA, Fedorova NV, Tashkin VY, Timofeeva TA, Ksenofontov AL, Loshkarev NA, Baratova LA, Jeffries CM, Svergun DI, Batishchev OV

Journal of virology, 2018

doi:10.1128/JVI.01450-18.

Hydration in aqueous solutions of ectoine and hydroxyectoine.

Sahle CJ, Schroer MA, Jeffries CM, Niskanen J

Physical Chemistry Chemical Physics, 2018

doi:10.1039/C8CP05308A.

Recombinant production of A1S_0222 from acinetobacter baumannii ATCC 17978 and confirmation of its DNA-(adenine N6)-methyltransferase activity.

Blaschke U, Suwono B, Zafari S, Ebersberger I, Skiebe E, Jeffries CM, Svergun DI, Wilharm G

Protein expression and purification, 2018

doi:10.1016/j.pep.2018.06.009.

Smaller capillaries improve the small-angle X-ray scattering signal and sample consumption for biomacromolecular solutions.

Schroer MA, Blanchet CE, Gruzinov AY, Gräwert MA, Brennich ME, Hajizadeh NR, Jeffries CM, Svergun DI

Journal of Synchrotron Radiation, 2018

doi:10.1107/S1600577518007907.

Machine Learning Methods for X-Ray Scattering Data Analysis from Biomacromolecular Solutions.

Franke D, Jeffries CM, Svergun DI

Biophysical journal, 2018

doi:10.1016/j.bpj.2018.04.018.

Consensus bayesian assessment of protein molecular mass from solution X-ray scattering data.

Hajizadeh NR, Franke D, Jeffries CM, Svergun DI.

Scientific Reports, 2018

doi:10.1038/s41598-018-25355-2.

Functional interaction of low-homology FRPs from different cyanobacteria with Synechocystis OCP

Slonimskiy YB, Maksimov EG, Lukashev EP, Moldenhauer M, Jeffries CM, Svergun DI, Friedrich T, Sluchanko NN.

BBA. Bioenergetics, 2018

doi:10.1016/j.bbabio.2018.03.001.

Sample and Buffer Preparation for SAXS.

Graewert MA, Jeffries CM

Advances in experimental medicine and biology, 2017

doi:10.1007/978-981-10-6038-0_2.

Influenza virus Matrix Protein M1 preserves its conformation with pH, changing multimerization state at the priming stage due to electrostatics.

Shtykova EV, Dadinova LA, Fedorova NV, Golanikov AE, Bogacheva EN, Ksenofontov AL, Baratova LA, Shilova LA, Tashkin VY, Galimzyanov TR, Jeffries CM, Svergun DI, Batishchev OV

Scientific reports, 2017

doi:10.1038/s41598-017-16986-y.

Small-angle X-Ray analysis of macromolecular structure: the structure of protein NS2 (NEP) in solution.

Shtykova, EV., Bogacheva, EN, Dadinova, LA, Jeffries, CM, Fedorova, NV, Golovko, AO, Baratova, LA, Batishchev, OV

Crystallography Reports, 2017

doi:10.1134/S1063774517060220.

Interactions between LHX3- and ISL1-family LIM-homeodomain transcription factors are conserved in Caenorhabditis elegans.

Bhati M, Llamosas E, Jacques DA, Jeffries CM, Dastmalchi S, Ripin N, Nicholas HR, Matthews JM

Scientific Reports, 2017

doi:10.1038/s41598-017-04587-8.

ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

Franke D, Petoukhov MV, Konarev PV, Panjkovich A, Tuukkanen A, Mertens HDT, Kikhney AG, Hajizadeh NR, Franklin JM, Jeffries CM, Svergun DI

Journal of Applied Crystallography, 2017

doi:10.1107/S1600576717007786.

The Shigella Virulence Factor IcsA Relieves N-WASP Autoinhibition by Displacing the Verprolin Homology/Cofilin/Acidic (VCA) Domain.

Mauricio RP, Jeffries CM, Svergun DI, Deane JE

The Journal of biological chemistry, 2016

doi:10.1074/jbc.m116.758003.

Validation of biological small-angle scattering data and models in SASBDB.

Kikhney A, Jeffries CM, Borges CR, Hajizadeh N, Manalastas KK, Svergun DI

Acta Crystallographica. Section A, Foundations of Crystallography, 2017

doi:10.1107/s2053273317081360.

Preparing monodisperse macromolecular samples for successful biological small-angle X-ray and neutron-scattering experiments.

Jeffries CM, Graewert MA, Blanchet CE, Langley DB, Whitten AE, Svergun DI

Nature protocols, 2016

doi:10.1038/nprot.2016.113.

X-Ray Solution Scattering Study of Four Escherichia coli Enzymes Involved in Stationary-Phase Metabolism

Dadinova LA, Shtykova EV, Konarev PV, Rodina EV, Snalina NE, Vorobyeva NN, Kurilova SA, Nazarova TI, Jeffries CM, Svergun DI.

PLoS ONE, 2016

doi:10.1371/journal.pone.0156105.

Structural characterization of the extracellular domain of CASPR2 and insights into its association with the novel ligand Contactin1.

Rubio-Marrero EN, Vincelli G, Jeffries CM, Shaikh TR, Pakos I, Ranaivoson FM, von Daake S, Demeler B, De Jaco A, Perkins G, Ellisman MH, Trewhella J, Comoletti D

The Journal of biological chemistry, 2016

doi:10.1074/jbc.M115.705681.

Domain-swap polymerization drives the self-assembly of the bacterial flagellar motor

Baker MAB, Hynson RMG, Ganuelas LA, Mohammadi NS, Liew CW, Rey AA, Duff AP, Whitten AE, Jeffries CM, Delalez NJ, Morimoto YV, Stock D, Armitage JP, Turberfield AJ, Namba K, Berry RM, Lee LK.

Nature Structural and Molecular Biology , 2016

doi:10.1038/nsmb.3172.

Expression, purification and crystallization of human Kynurenine Aminotransferase 2 exploiting a highly optimized codon set.

Sun G, Nematollahi A, Nadvi NA, Kwan AH, Jeffries CM, Church W

Protein expression and purification, 2016

doi:10.1016/j.pep.2016.01.004.

Exploring the structure of biological macromolecules in solution using Quokka, the small angle neutron scattering instrument, at ANSTO.

Wood K, Jeffries CM, Knott RB, Sokolova A, Jacques DA, Duff AP

Nuclear Instruments and Methods in Physics Research Section A, 2015

doi:10.1016/j.nima.2015.06.034.

Automated pipeline for purification, biophysical and x-ray analysis of biomacromolecular solutions.

Graewert MA, Franke D, Jeffries CM, Blanchet CE, Ruskule D, Kuhle K, Flieger A, Schäfer B, Tartsch B, Meijers R, Svergun DI

Scientific reports, 2015

doi:10.1038/srep10734.

Cooperative folding of intrinsically disordered domains drives assembly of a strong elongated protein.

Gruszka DT, Whelan F, Farrance OE, Fung HK, Paci E, Jeffries CM, Svergun DI, Baldock C, Baumann CG, Brockwell DJ, Potts JR, Clarke J

Nature communications, 2015

doi:10.1038/ncomms8271.

Correlation Map, a goodness-of-fit test for one-dimensional X-ray scattering spectra.

Franke D, Jeffries CM, Svergun DI

Nature Methods, 2015

doi:10.1038/nmeth.3358.

Versatile sample environments and automation for biological solution X-ray scattering experiments at the P12 beamline (PETRA III, DESY).

Blanchet CE, Spilotros A, Schwemmer F, Graewert MA, Kikhney A, Jeffries CM, Franke D, Mark D, Zengerle R, Cipriani F, Fiedler S, Roessle M, Svergun DI

Journal of applied crystallography, 2015

doi:10.1107/s160057671500254x.

Limiting radiation damage for high-brilliance biological solution scattering: practical experience at the EMBL P12 beamline PETRAIII

Jeffries CM, Graewert MA, Svergun DI, Blanchet CE

Journal of Synchrotron Radiation, 2015

doi:10.1107/S1600577515000375.

SASBDB, a repository for biological small-angle scattering data

Valentini E, Kikhney AG, Previtali G, Jeffries CM, Svergun DI

Nucleic acids research, 2014

doi:10.1093/nar/gku1047.

High-throughput studies of protein shapes and interactions by synchrotron small-angle x-ray scattering.

Jeffries CM, Svergun DI

Methods in molecular biology (Clifton, N.J.), 2015

doi:10.1007/978-1-4939-2230-7_15.

The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

Dunne M, Mertens HD, Garefalaki V, Jeffries CM, Thompson A, Lemke EA, Svergun DI, Mayer MJ, Narbad A, Meijers R

PLoS pathogens, 2014

doi:10.1371/journal.ppat.1004228.

K7del is a common TPM2 gene mutation associated with nemaline myopathy and raised myofibre calcium sensitivity.

Mokbel N, Ilkovski B, Kreissl M, Memo M, Jeffries CM, Marttila M, Lehtokari VL, Lemola E, Grönholm M, Yang N, Menard D, Marcorelles P, Echaniz-Laguna A, Reimann J, Vainzof M, Monnier N, Ravenscroft G, McNamara E, Nowak KJ, Laing NG, Wallgren-Pettersson C, Trewhella J, Marston S, Ottenheijm C, North KN, Clarke NF

Brain : a journal of neurology, 2013

doi:10.1093/brain/aws348.

Structural analysis of influenza A virus matrix protein M1 and its self-assemblies at low pH

Shtykova EV, Baratova LA, Fedorova NV, Radyukhin VA, Ksenofontov AL, Volkov VV, Shishkov AV, Dolgov AA, Shilova LA, Batishchev OV, Jeffries CM, Svergun DI

PloS one, 2013

doi:10.1371/journal.pone.0082431.

The motif of human cardiac myosin-binding protein C is required for its Ca2+-dependent interaction with calmodulin.

Lu Y, Kwan AH, Jeffries CM, Guss JM, Trewhella J

The Journal of biological chemistry, 2012

doi:10.1074/jbc.m112.383299.

Solution structure studies of monomeric human TIP47/perilipin-3 reveal a highly extended conformation.

Hynson RM, Jeffries CM, Trewhella J, Cocklin S

Proteins, 2012

doi:10.1002/prot.24095.

Calmodulin binds a highly extended HIV-1 MA protein that refolds upon its release.

Taylor JE, Chow JY, Jeffries CM, Kwan AH, Duff AP, Hamilton WA, Trewhella J

Biophysical journal, 2012

doi:10.1016/j.bpj.2012.06.042.

Crystallography and small-angle scattering of carbohydrate–protein complexes and glycoproteins.

Jeffries CM, Farrugia W, Ramsland PA

2012

doi:.

Small-angle scattering.

Jeffries CM, Trewhella J

2012

doi:.

Solution structure of the LIM-homeodomain transcription factor complex Lhx3/Ldb1 and the effects of a pituitary mutation on key Lhx3 interactions.

Bhati M, Lee C, Gadd MS, Jeffries CM, Kwan A, Whitten AE, Trewhella J, Mackay JP, Matthews JM

PloS one, 2012

doi:10.1371/journal.pone.0040719.

Structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification.

Gadd MS, Bhati M, Jeffries CM, Langley DB, Trewhella J, Guss JM, Matthews JM

The Journal of biological chemistry, 2011

doi:10.1074/jbc.m111.248559.

Human cardiac myosin binding protein C: structural flexibility within an extended modular architecture.

Jeffries CM, Lu Y, Hynson RM, Taylor JE, Ballesteros M, Kwan AH, Trewhella J

Journal of molecular biology, 2011

doi:10.1016/j.jmb.2011.10.029.

The C0C1 fragment of human cardiac myosin binding protein C has common binding determinants for both actin and myosin.

Lu Y, Kwan AH, Trewhella J, Jeffries CM

Journal of molecular biology, 2011

doi:10.1016/j.jmb.2011.09.026.

The modular structure of haemagglutinin/adhesin regions in gingipains of Porphyromonas gingivalis.

Li N, Yun P, Jeffries CM, Langley D, Gamsjaeger R, Church WB, Hunter N, Collyer CA

Molecular microbiology, 2011

doi:10.1111/j.1365-2958.2011.07768.x.

The N-terminal domains of myosin binding protein C can bind polymorphically to F-actin.

Orlova A, Galkin VE, Jeffries CM, Egelman EH, Trewhella J

Journal of molecular biology, 2011

doi:10.1016/j.jmb.2011.07.056.

Activation of the retroviral budding factor ALIX.

Zhai Q, Landesman MB, Chung HY, Dierkers A, Jeffries CM, Trewhella J, Hill CP, Sundquist WI

Journal of virology, 2011

doi:10.1128/jvi.02653-10.

Invited review: probing the structures of muscle regulatory proteins using small-angle solution scattering.

Lu Y, Jeffries CM, Trewhella J

Biopolymers, 2011

doi:10.1002/bip.21624.

Effects of macromolecular crowding on an intrinsically disordered protein characterized by small-angle neutron scattering with contrast matching.

Johansen D, Jeffries CM, Hammouda B, Trewhella J, Goldenberg DP

Biophysical journal, 2011

doi:10.1016/j.bpj.2011.01.020.

The macromolecular architecture of extracellular domain of alphaNRXN1: domain organization, flexibility, and insights into trans-synaptic disposition.

Comoletti D, Miller MT, Jeffries CM, Wilson J, Demeler B, Taylor P, Trewhella J, Nakagawa T

Structure (London, England : 1993), 2010

doi:10.1016/j.str.2010.06.005.

Calmodulin disrupts the structure of the HIV-1 MA protein.

Chow JY, Jeffries CM, Kwan AH, Guss JM, Trewhella J

Journal of molecular biology, 2010

doi:10.1016/j.jmb.2010.05.022.

LIM domain binding proteins 1 and 2 have different oligomeric states.

Cross AJ, Jeffries CM, Trewhella J, Matthews JM

Journal of molecular biology, 2010

doi:10.1016/j.jmb.2010.04.006.

A picornaviral loop-to-loop replication complex.

Claridge JK, Headey SJ, Chow JY, Schwalbe M, Edwards PJ, Jeffries CM, Venugopal H, Trewhella J, Pascal SM

Journal of structural biology, 2009

doi:10.1016/j.jsb.2009.02.010.

Histidine kinase regulation by a cyclophilin-like inhibitor.

Jacques DA, Langley DB, Jeffries CM, Cunningham KA, Burkholder WF, Guss JM, Trewhella J

Journal of molecular biology, 2008

doi:10.1016/j.jmb.2008.09.017.

Competition between LIM-binding domains

Matthews JM, Bhati M, Craig VJ, Deane JE, Jeffries C, Lee C, Nancarrow AL, Ryan DP, Sunde M

BIOCHEMICAL SOCIETY TRANSACTIONS, 2008

doi:10.1042/BST0361393.

Cardiac myosin-binding protein C decorates F-actin: implications for cardiac function.

Whitten AE, Jeffries CM, Harris SP, Trewhella J

Proceedings of the National Academy of Sciences of the United States of America, 2008

doi:10.1073/pnas.0808903105.

Small-angle X-ray scattering reveals the N-terminal domain organization of cardiac myosin binding protein C.

Jeffries CM, Whitten AE, Harris SP, Trewhella J

Journal of molecular biology, 2008

doi:10.1016/j.jmb.2008.01.080.

Ligand-induced conformational changes via flexible linkers in the amino-terminal region of the inositol 1,4,5-trisphosphate receptor.

Chan J, Whitten AE, Jeffries CM, Bosanac I, Mal TK, Ito J, Porumb H, Michikawa T, Mikoshiba K, Trewhella J, Ikura M

Journal of molecular biology, 2007

doi:10.1016/j.jmb.2007.08.057.

Stabilization of a binary protein complex by intein-mediated cyclization.

Jeffries CM, Graham SC, Stokes PH, Collyer CA, Guss JM, Matthews JM

Protein science : a publication of the Protein Society, 2006

doi:10.1110/ps.062377006.

MICREDOX (R) - development of a ferricyanide-mediated rapid biochemical oxygen demand method using an immobilised Proteus vulgaris biocomponent

Pasco N, Baronian KB, Jeffries C, Webber J, Hay J

BIOSENSORS & BIOELECTRONICS, 2004

doi:10.1016/j.bios.2004.02.016.

Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution.

Yang H, Carr PD, McLoughlin SY, Liu JW, Horne I, Qiu X, Jeffries CM, Russell RJ, Oakeshott JG, Ollis DL

Protein engineering, 2003

doi:10.1093/proeng/gzg013.

Biochemical mediator demand - a novel rapid alternative for measuring biochemical oxygen demand

Pasco N, Baronian K, Jeffries C, Hay J

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2000

doi:10.1007/s002530051666.

Of barn owls and bankers: a lush variety of alpha/beta hydrolases

Heikinheimo P, Goldman A, Jeffries C, Ollis DL

STRUCTURE, 1999

doi:10.1016/S0969-2126(99)80079-3.

Characterisation of a thermophilic L-glutamate dehydrogenase biosensor for amperometric determination of L-glutamate by flow injection analysis

Pasco N, Jeffries C, Davies Q, Downard AJ, Roddick-Lanzilotta AD, Gorton L

BIOSENSORS & BIOELECTRONICS, 1999

doi:10.1016/S0956-5663(98)00120-1.

Evaluation of a thermophile enzyme for a carbon paste amperometric biosensor: L-glutamate dehydrogenase

Jeffries C, Pasco N, Baronian K, Gorton L

BIOSENSORS & BIOELECTRONICS, 1997

doi:10.1016/S0956-5663(97)85340-7.