Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma.

Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE

Nature communications, 2024

doi:10.1038/s41467-024-47031-y.

Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins.

Griffith-Jones S, Álvarez L, Mukhopadhyay U, Gharbi S, Rettel M, Adams M, Hennig J, Bhogaraju S

The EMBO journal, 2024

doi:10.1038/s44318-024-00058-9.

Macromolecular crowding in human tenocyte and skin fibroblast cultures: a comparative analysis.

Djalali-Cuevas A, Rettel M, Stein F, Savitski M, Kearns S, Kelly J, Biggs M, Skoufos I, Tzora A, Prassinos N, Diakakis N, Zeugolis DI

Materials Today Bio, 2024

doi:10.1016/j.mtbio.2024.100977.

The RNA-binding protein landscapes differ between mammalian organs and cultured cells.

Perez-Perri JI, Ferring-Appel D, Huppertz I, Schwarzl T, Sahadevan S, Stein F, Rettel M, Galy B, Hentze MW

Nature communications, 2023

doi:10.1038/s41467-023-37494-w.

Unravelling metabolic cross-feeding in a yeast-bacteria community using 13 C-based proteomics.

Gabrielli N, Maga-Nteve C, Kafkia E, Rettel M, Loeffler J, Kamrad S, Typas A, Patil KR

Molecular systems biology, 2023

doi:10.15252/msb.202211501.

The membrane-associated protein 17 (MAP17) is upregulated in response to empagliflozin on top of RAS blockade in experimental diabetic nephropathy.

Vergara A, Llorens-Cebrià C, Martos N, Martínez-Díaz I, Stein F, Domínguez-Báez P, Molina-Van den Bosch M, Rettel M, Benito B, Bermejo S, Pieper MP, Jacobs C, Soler MJ

Clinical science (London, England : 1979), 2022

doi:10.1042/CS20220447.

The augmin complex architecture reveals structural insights into microtubule branching.

Zupa E, Würtz M, Neuner A, Hoffmann T, Rettel M, Böhler A, Vermeulen BJA, Eustermann S, Schiebel E, Pfeffer S

Nature communications, 2022

doi:10.1038/s41467-022-33228-6.

Sumoylation of Cas9 at lysine 848 regulates protein stability and DNA binding.

Ergünay T, Ayhan Ö, Celen AB, Georgiadou P, Pekbilir E, Abaci YT, Yesildag D, Rettel M, Sobhiafshar U, Ogmen A, Emre NT, Sahin U

Life science alliance, 2022

doi:10.26508/lsa.202101078.

CaMKK2 facilitates Golgi-associated vesicle trafficking to sustain cancer cell proliferation.

Stewart LM, Gerner L, Rettel M, Stein F, Burrows JF, Mills IG, Evergren E

Cell death & disease, 2021

doi:10.1038/s41419-021-04335-x.

Structure and dynamics of the quaternary hunchback mRNA translation repression complex.

Macošek J, Simon B, Linse JB, Jagtap PKA, Winter SL, Foot J, Lapouge K, Perez K, Rettel M, Ivanović MT, Masiewicz P, Murciano B, Savitski MM, Loedige I, Hub JS, Gabel F, Hennig J

Nucleic acids research, 2021

doi:10.1093/nar/gkab635.

P38α-MAPK phosphorylates Snapin and reduces Snapin-mediated BACE1 transportation in APP-transgenic mice.

Schnöder L, Tomic I, Schwindt L, Helm D, Rettel M, Schulz-Schaeffer W, Krause E, Rettig J, Fassbender K, Liu Y

FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021

doi:10.1096/fj.202100017R.

Structure of the mycobacterial ESX-5 type VII secretion system pore complex.

Beckham KSH, Ritter C, Chojnowski G, Ziemianowicz DS, Mullapudi E, Rettel M, Savitski MM, Mortensen SA, Kosinski J, Wilmanns M

Science advances, 2021

doi:10.1126/sciadv.abg9923.

Quality standards in proteomics research facilities: common standards and quality procedures are essential for proteomics facilities and their users.

Chiva C, Mendes Maia T, Panse C, Stejskal K, Douché T, Matondo M, Loew D, Helm D, Rettel M, Mechtler K, Impens F, Nanni P, Shevchenko A, Sabidó E

EMBO reports, 2021

doi:10.15252/embr.202152626.

Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes.

Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Gür K, Ölschläger J, Kühl F, Martin J, Ramirez-Pedraza M, Fernandez M, Doroudgar S, Méndez R, Katus HA, Hentze MW, Völkers M

Cell reports, 2021

doi:10.1016/j.celrep.2021.109100.

Global mapping of Salmonella enterica-host protein-protein interactions during infection.

Walch P, Selkrig J, Knodler LA, Rettel M, Stein F, Fernandez K, Viéitez C, Potel CM, Scholzen K, Geyer M, Rottner K, Steele-Mortimer O, Savitski MM, Holden DW, Typas A

Cell Host and Microbe, 2021

doi:10.1016/j.chom.2021.06.004.

NMD inhibition by 5-azacytidine augments presentation of immunogenic frameshift-derived neoepitopes.

Becker JP, Helm D, Rettel M, Stein F, Hernandez-Sanchez A, Urban K, Gebert J, Kloor M, Neu-Yilik G, von Knebel Doeberitz M, Hentze MW, Kulozik AE

iScience, 2021

doi:10.1016/j.isci.2021.102389.

SARS-CoV-2 infection remodels the host protein thermal stability landscape.

Selkrig J, Stanifer M, Mateus A, Mitosch K, Barrio-Hernandez I, Rettel M, Kim H, Voogdt CGP, Walch P, Kee C, Kurzawa N, Stein F, Potel C, Jarzab A, Kuster B, Bartenschlager R, Boulant S, Beltrao P, Typas A, Savitski MM

Molecular systems biology, 2021

doi:10.15252/msb.202010188.

Aggregation and disaggregation features of the human proteome.

Määttä TA, Rettel M, Sridharan S, Helm D, Kurzawa N, Stein F, Savitski MM

Molecular systems biology, 2020

doi:10.15252/msb.20209500.

Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins.

Backlund M, Stein F, Rettel M, Schwarzl T, Perez-Perri JI, Brosig A, Zhou Y, Neu-Yilik G, Hentze MW, Kulozik AE

Nucleic acids research, 2020

doi:10.1093/nar/gkaa256.

Human mast cell proteome reveals unique lineage, putative functions, and structural basis for cell ablation.

Plum T, Wang X, Rettel M, Krijgsveld J, Feyerabend TB, Rodewald HR

Immunity, 2020

doi:10.1016/j.immuni.2020.01.012.

A misprocessed form of Apolipoprotein A-I is specifically associated with recurrent focal segmental glomerulosclerosis.

Jacobs-Cachá C, Puig-Gay N, Helm D, Rettel M, Sellarès J, Meseguer A, Savitski MM, Moreso FJ, Soler MJ, Seron D, Lopez-Hellin J

Scientific reports, 2020

doi:10.1038/s41598-020-58197-y.

Monitoring cell-type-specific gene expression using ribosome profiling in vivo during cardiac hemodynamic stress.

Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann C, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Mauz V, Friedrich UA, Kramer G, Backs J, Dieterich C, Katus HA, Völkers M

Circulation research, 2019

doi:10.1161/CIRCRESAHA.119.314817.

Secretome profiling of heterotypic spheroids suggests a role of fibroblasts in HIF-1 pathway modulation and colorectal cancer photodynamic resistance.

Lamberti MJ, Rettel M, Krijgsveld J, Rivarola VA, Rumie Vittar NB

Cellular oncology (Dordrecht), 2019

doi:10.1007/s13402-018-00418-8.

Effect of Sec61 interaction with Mpd1 on endoplasmic reticulum-associated degradation.

Pereira F, Rettel M, Stein F, Savitski MM, Collinson I, Römisch K

PloS one, 2019

doi:10.1371/journal.pone.0211180.

Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture.

Perez-Perri JI, Rogell B, Schwarzl T, Stein F, Zhou Y, Rettel M, Brosig A, Hentze MW

Nature communications, 2018

doi:10.1038/s41467-018-06557-8.

TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

Jethwa A, Słabicki M, Hüllein J, Jentzsch M, Dalal V, Rabe S, Wagner L, Walther T, Klapper W, Bohnenberger H, Rettel M, Lu J, Smits AH, Stein F, Savitski MM, Huber W, Aylon Y, Oren M, Zenz T

Blood, 2018

doi:10.1182/blood-2017-09-806679.

Author Correction: Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting.

Schulze WM, Stein F, Rettel M, Nanao M, Cusack S

Nature communications, 2018

doi:10.1038/s41467-018-04643-5.

Laboratory evolution reveals regulatory and metabolic trade-offs of glycerol utilization in Saccharomyces cerevisiae.

Strucko T, Zirngibl K, Pereira F, Kafkia E, Mohamed ET, Rettel M, Stein F, Feist AM, Jouhten P, Patil KR, Forster J

Metabolic engineering, 2018

doi:10.1016/j.ymben.2018.03.006.

Structural analysis of human ARS2 as a platform for co-transcriptional RNA sorting.

Schulze WM, Stein F, Rettel M, Nanao M, Cusack S

Nature communications, 2018

doi:10.1038/s41467-018-04142-7.

Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen.

Do H, Makthal N, VanderWal AR, Rettel M, Savitski MM, Peschek N, Papenfort K, Olsen RJ, Musser JM, Kumaraswami M

Proceedings of the National Academy of Sciences of the United States of America, 2017

doi:10.1073/pnas.1705972114.

Specific RNP capture with antisense LNA/DNA mixmers.

Rogell BM, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW

RNA (New York, N.Y.), 2017

doi:10.1261/rna.060798.117.

Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.

Beckham KS, Ciccarelli L, Bunduc CM, Mertens HD, Ummels R, Lugmayr W, Mayr J, Rettel M, Savitski MM, Svergun DI, Bitter W, Wilmanns M, Marlovits TC, Parret AH, Houben EN

Nature microbiology, 2017

doi:10.1038/nmicrobiol.2017.47.

In planta determination of the mRNA-binding proteome of Arabidopsis etiolated seedlings.

Reichel M, Liao Y, Rettel M, Ragan C, Evers M, Alleaume AM, Horos R, Hentze MW, Preiss T, Millar AA

The Plant cell, 2016

doi:10.1105/tpc.16.00562.

Evaluation of novel Streptococcus pyogenes vaccine candidates incorporating multiple conserved sequences from the C-repeat region of the M-protein.

Bauer MJ, Georgousakis MM, Vu T, Henningham A, Hofmann A, Rettel M, Hafner LM, Sriprakash KS, McMillan DJ

Vaccine, 2012

doi:10.1016/j.vaccine.2011.12.115.