CLEMSite, a software for automated phenotypic screens using light microscopy and FIB-SEM.

Serra Lleti JM, Steyer AM, Schieber NL, Neumann B, Tischer C, Hilsenstein V, Holtstrom M, Unrau D, Kirmse R, Lucocq JM, Pepperkok R, Schwab Y

The Journal of cell biology, 2022

doi:10.1083/jcb.202209127.

Systems Approaches to Unravel Molecular Function: High-content siRNA Screen Identifies TMEM16A Traffic Regulators as Potential Drug Targets for Cystic Fibrosis.

Pinto MC, Botelho HM, Silva IAL, Railean V, Neumann B, Pepperkok R, Schreiber R, Kunzelmann K, Amaral MD

Journal of molecular biology, 2022

doi:10.1016/j.jmb.2021.167436.

Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity.

Khan MM, Zukowska-Kasprzyk J, Neumann B, Halavatyi A, Tischer C, Haberkant P, Stein F, Jung F, Landry J, Lewis J, Pepperkok R

ERJ open research, 2021

doi:10.1183/23120541.lsc-2021.33.

Genetic screening identifies a SUMO protease dynamically maintaining centromeric chromatin.

Mitra S, Bodor DL, David AF, Abdul-Zani I, Mata JF, Neumann B, Reither S, Tischer C, Jansen LET

Nature communications, 2020

doi:10.1038/s41467-019-14276-x.

A solid-phase transfection platform for arrayed CRISPR screens.

Serçin Ö, Reither S, Roidos P, Ballin N, Palikyras S, Baginska A, Rein K, Llamazares M, Halavatyi A, Winter H, Muley T, Jurkowska RZ, Abdollahi A, Zenke FT, Neumann B, Mardin BR

Molecular systems biology, 2019

doi:10.15252/msb.20198983.

Author Correction: A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Corallino S, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G

Nature communications, 2018

doi:10.1038/s41467-018-04515-y.

A RAB35-p85/PI3K axis controls oscillatory apical protrusions required for efficient chemotactic migration.

Salvatore C, Malinverno C, Neumann B, Tischer C, Palamidessi A, Frittoli E, Panagiotakopoulou M, Disanza A, Malet-Engra G, Nastaly P, Galli C, Luise C, Bertalot G, Pece S, Di Fiore PP, Gauthier N, Ferrari A, Maiuri P, Scita G

Nature communications, 2018

doi:10.1038/s41467-018-03571-8.

Profiling DNA damage response following mitotic perturbations.

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C

Nature communications, 2016

doi:10.1038/ncomms13887.

Ki-67 acts as a biological surfactant to disperse mitotic chromosomes.

Cuylen S, Blaukopf C, Politi AZ, Müller-Reichert T, Neumann B, Poser I, Ellenberg J, Hyman AA, Gerlich DW

Nature, 2016

doi:10.1038/nature18610.

Erratum: Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.

Frei DM, Hodneland E, Rios-Mondragon I, Burtey A, Neumann B, Bulkescher J, Schölermann J, Pepperkok R, Gerdes HH, Kögel T

Scientific reports, 2015

doi:10.1038/srep14158.

Novel microscopy-based screening method reveals regulators of contact-dependent intercellular transfer.

Frei DM, Hodneland E, Rios-Mondragon I, Burtey A, Neumann B, Bulkescher J, Schölermann J, Pepperkok R, Gerdes HH, Kögel T

Scientific reports, 2015

doi:10.1038/srep12879.

The catalytically inactive tyrosine phosphatase HD-PTP/PTPN23 is a novel regulator of SMN complex localization.

Husedzinovic A, Neumann B, Reymann J, Draeger-Meurer S, Chari A, Erfle H, Fischer U, Gruss OJ

Molecular biology of the cell, 2014

doi:10.1091/mbc.E14-06-1151.

SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs

van der Lelij P, Stocsits RR, Ladurner R, Petzold G, Kreidl E, Koch B, Schmitz J, Neumann B, Ellenberg J, Peters JM

The EMBO journal, 2014

doi:10.15252/embj.201488202.

Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division.

Rohn JL, Patel JV, Neumann B, Bulkescher J, Mchedlishvili N, McMullan RC, Quintero OA, Ellenberg J, Baum B

Current biology : CB, 2014

doi:10.1016/j.cub.2014.09.045.

MAP1S controls microtubule stability throughout the cell cycle in human cells.

Tegha-Dunghu J, Bausch E, Neumann B, Wuensche A, Walter T, Ellenberg J, Gruss OJ

Journal of cell science, 2014

doi:10.1242/jcs.136457.

The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy.

Asteriti IA, Di Cesare E, De Mattia F, Hilsenstein V, Neumann B, Cundari E, Lavia P, Guarguaglini G

Oncotarget, 2014

doi:10.18632/oncotarget.2190.

Dynamical modelling of phenotypes in a genome-wide RNAi live-cell imaging assay.

Pau G, Walter T, Neumann B, Hériché JK, Ellenberg J, Huber W

BMC bioinformatics, 2013

doi:10.1186/1471-2105-14-308.

Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation

Casanova CM, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C

PloS one, 2012

doi:10.1371/journal.pone.0045943.

TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

Gudjonsson T, Altmeyer M, Savic V, Toledo L, Dinant C, Grøfte M, Bartkova J, Poulsen M, Oka Y, Bekker-Jensen S, Mailand N, Neumann B, Heriche JK, Shearer R, Saunders D, Bartek J, Lukas J, Lukas C

Cell, 2012

doi:10.1016/j.cell.2012.06.039.

Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway

Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Hériché JK, Neumann B, Mateos A, Blake J, Bechtel S, Benes V, Wiemann S, Ellenberg J, Pepperkok R

Nature cell biology, 2012

doi:10.1038/ncb2510.

Nucleoporin NUP153 guards genome integrity by promoting nuclear import of 53BP1.

Moudry P, Lukas C, Macurek L, Neumann B, Heriche JK, Pepperkok R, Ellenberg J, Hodny Z, Lukas J, Bartek J

Cell death and differentiation, 2012

doi:10.1038/cdd.2011.150.

Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy

Stadler C, Hjelmare M, Neumann B, Jonasson K, Pepperkok R, Uhlén M, Lundberg E

Journal of proteomics, 2012

doi:10.1016/j.jprot.2012.01.030.

Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases

Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W

Genome research, 2011

doi:10.1101/gr.116087.110.

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

Lukas C, Savic V, Bekker-Jensen S, Doil C, Neumann B, Pedersen RS, Grøfte M, Chan KL, Hickson ID, Bartek J, Lukas J

Nature cell biology, 2011

doi:10.1038/ncb2201.

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.

Held M, Schmitz MH, Fischer B, Walter T, Neumann B, Olma MH, Peter M, Ellenberg J, Gerlich DW

Nature methods, 2010

doi:10.1038/nmeth.1486.

High-throughput microscopy using live mammalian cells.

Terjung S, Walter T, Seitz A, Neumann B, Pepperkok R, Ellenberg J

Cold Spring Harbor protocols, 2010

doi:10.1101/pdb.top84.

Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes

Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J

Nature, 2010

doi:10.1038/nature08869.

Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging

Walter T, Held M, Neumann B, Hériché JK, Conrad C, Pepperkok R, Ellenberg J

Journal of structural biology, 2010

doi:10.1016/j.jsb.2009.10.004.

Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell plates

Erfle H, Neumann B, Rogers P, Bulkescher J, Ellenberg J, Pepperkok R

Journal of biomolecular screening, 2008

doi:10.1177/1087057108320133.

EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.

Tegha-Dunghu J, Neumann B, Reber S, Krause R, Erfle H, Walter T, Held M, Rogers P, Hupfeld K, Ruppert T, Ellenberg J, Gruss OJ

Journal of cell science, 2008

doi:10.1242/jcs.019174.

A genome wide RNAI screen by time lapse microscopy in order to identify mitotic genes - Computational aspects and challenges.

Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J

2008 IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO, VOLS 1-4, 2008

doi:10.1109/ISBI.2008.4540999.

Reverse transfection on cell arrays for high content screening microscopy.

Erfle H, Neumann B, Liebel U, Rogers P, Held M, Walter T, Ellenberg J, Pepperkok R

Nature protocols, 2007

doi:10.1038/nprot.2006.483.

High-throughput RNAi screening by time-lapse imaging of live human cells.

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J

Nature methods, 2006

doi:10.1038/nmeth876.

Time-lapse microscopy-based genome wide RNAI screening in live human cells.

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J

2006 3RD IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: MACRO TO NANO, VOLS 1-3, 2006

doi:10.1109/ISBI.2006.1624898.

Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans.

Sönnichsen B, Koski LB, Walsh A, Marschall P, Neumann B, Brehm M, Alleaume AM, Artelt J, Bettencourt P, Cassin E, Hewitson M, Holz C, Khan M, Lazik S, Martin C, Nitzsche B, Ruer M, Stamford J, Winzi M, Heinkel R, Röder M, Finell J, Häntsch H, Jones SJ, Jones M, Piano F, Gunsalus KC, Oegema K, Gönczy P, Coulson A, Hyman AA, Echeverri CJ

Nature, 2005

doi:10.1038/nature03353.

RGD-mutants of B-lymphotropic polyomavirus capsids specifically bind to alpha(v)beta3 integrin.

Langner J, Neumann B, Goodman SL, Pawlita M

Archives of virology, 2004

doi:10.1007/s00705-004-0374-z.

A serine-kinase associated with the p127-l(2)gl tumour suppressor of Drosophila may regulate the binding of p127 to nonmuscle myosin II heavy chain and the attachment of p127 to the plasma membrane.

Kalmes A, Merdes G, Neumann B, Strand D, Mechler BM

Journal of cell science, 1996

doi:.

A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain.

Strand D, Unger S, Corvi R, Hartenstein K, Schenkel H, Kalmes A, Merdes G, Neumann B, Krieg-Schneider F, Coy JF

Oncogene, 1995

doi:.

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain.

Strand D, Jakobs R, Merdes G, Neumann B, Kalmes A, Heid HW, Husmann I, Mechler BM

The Journal of cell biology, 1994

doi:10.1083/jcb.127.5.1361.