MemPrep, a new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress.

Reinhard J, Starke L, Klose C, Haberkant P, Hammarén H, Stein F, Klein O, Berhorst C, Stumpf H, Sáenz JP, Hub J, Schuldiner M, Ernst R

The EMBO journal, 2024

doi:10.1038/s44318-024-00063-y.

Trifunctional sphinganine: a new tool to dissect sphingolipid function.

Farley S, Stein F, Haberkant P, Tafesse FG, Schultz C

ACS chemical biology, 2024

doi:10.1021/acschembio.3c00554.

Global Hfq-mediated RNA interactome of nitrogen starved Escherichia coli uncovers a conserved post-transcriptional regulatory axis required for optimal growth recovery.

McQuail J, Matera G, Gräfenhan T, Bischler T, Haberkant P, Stein F, Vogel J, Wigneshweraraj S

Nucleic acids research, 2023

doi:10.1093/nar/gkad1211.

Flow in fetoplacental-like microvessels in vitro enhances perfusion, barrier function, and matrix stability.

Cherubini M, Erickson S, Padmanaban P, Haberkant P, Stein F, Beltran-Sastre V, Haase K

Science advances, 2023

doi:10.1126/sciadv.adj8540.

Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins.

Groh C, Haberkant P, Stein F, Filbeck S, Pfeffer S, Savitski MM, Boos F, Herrmann JM

Life science alliance, 2023

doi:10.26508/lsa.202201805.

Dual truncation of tau by caspase-2 accelerates its CHIP-mediated degradation.

Reinhardt L, Musacchio F, Bichmann M, Behrendt A, Ercan-Herbst E, Stein J, Becher I, Haberkant P, Mader J, Schöndorf DC, Schmitt M, Korffmann J, Reinhardt P, Pohl C, Savitski M, Klein C, Gasparini L, Fuhrmann M, Ehrnhoefer DE

Neurobiology of disease, 2023

doi:10.1016/j.nbd.2023.106126.

Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.

Madel RJ, Börger V, Dittrich R, Bremer M, Tertel T, Phuong NNT, Baba HA, Kordelas L, Staubach S, Stein F, Haberkant P, Hackl M, Grillari R, Grillari J, Buer J, Horn PA, Westendorf AM, Brandau S, Kirschning CJ, Giebel B

Cytotherapy, 2023

doi:10.1016/j.jcyt.2023.03.008.

Redox proteomic profile of tirapazamine-resistant murine hepatoma cells.

Nemeikaitė-Čėnienė A, Haberkant P, Kučiauskas D, Stein F, Čėnas N

International journal of molecular sciences, 2023

doi:10.3390/ijms24076863.

Lysosome-targeted multifunctional lipid probes reveal the sterol transporter NPC1 as a sphingosine interactor.

Altuzar J, Notbohm J, Stein F, Haberkant P, Hempelmann P, Heybrock S, Worsch J, Saftig P, Höglinger D

Proceedings of the National Academy of Sciences of the United States of America, 2023

doi:10.1073/pnas.2213886120.

Extended N-terminal acetyltransferase Naa50 in filamentous fungi adds to Naa50 diversity.

Weidenhausen J, Kopp J, Ruger-Herreros C, Stein F, Haberkant P, Lapouge K, Sinning I

International journal of molecular sciences, 2022

doi:10.3390/ijms231810805.

SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer's disease.

Bichmann M, Prat Oriol N, Ercan-Herbst E, Schöndorf DC, Gomez Ramos B, Schwärzler V, Neu M, Schlüter A, Wang X, Jin L, Hu C, Tian Y, Ried JS, Haberkant P, Gasparini L, Ehrnhoefer DE

Molecular neurodegeneration, 2021

doi:10.1186/s13024-021-00468-x.

Increased levels of mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol.

Schlagowski AM, Knöringer K, Morlot S, Sánchez Vicente A, Flohr T, Krämer L, Boos F, Khalid N, Ahmed S, Schramm J, Murschall LM, Haberkant P, Stein F, Riemer J, Westermann B, Braun RJ, Winklhofer KF, Charvin G, Herrmann JM

The EMBO journal, 2021

doi:10.15252/embj.2021107913.

Glucocorticoids exacerbate TGFß1 mediated fibrotic signalling in lung fibroblasts by inhibition of metalloproteinase expression and activity.

Khan MM, Zukowska-Kasprzyk J, Neumann B, Halavatyi A, Tischer C, Haberkant P, Stein F, Jung F, Landry J, Lewis J, Pepperkok R

ERJ open research, 2021

doi:10.1183/23120541.lsc-2021.33.

The central role of salivary metalloproteases in host acquired resistance to tick feeding.

Perner J, Helm D, Haberkant P, Hatalova T, Kropackova S, Ribeiro JM, Kopacek P

Frontiers in cellular and infection microbiology, 2020

doi:10.3389/fcimb.2020.563349.

Stroma transcriptomic and proteomic profile of prostate cancer metastasis xenograft models reveals prognostic value of stroma signatures.

Karkampouna S, De Filippo MR, Ng CKY, Klima I, Zoni E, Spahn M, Stein F, Haberkant P, Thalmann GN, Kruithof de Julio M

Cancers, 2020

doi:10.3390/cancers12123786.

Pseudo-RNA-binding domains mediate RNA structure specificity in Upstream of N-Ras.

Hollmann NM, Jagtap PKA, Masiewicz P, Guitart T, Simon B, Provaznik J, Stein F, Haberkant P, Sweetapple LJ, Villacorta L, Moojiman D, Benes V, Savitski MM, Gebauer F, Hennig J

2020

doi:10.1016/j.celrep.2020.107930.

The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range.

Girstmair H, Tippel F, Lopez A, Tych K, Stein F, Haberkant P, Schmid PWN, Helm D, Rief M, Sattler M, Buchner J

Nature communications, 2019

doi:10.1038/s41467-019-11518-w.

Asparagine endopeptidase cleaves tau at N167 after uptake into microglia.

Behrendt A, Bichmann M, Ercan-Herbst E, Haberkant P, Schöndorf DC, Wolf M, Fahim SA, Murolo E, Ehrnhoefer DE

Neurobiology of disease, 2019

doi:10.1016/j.nbd.2019.104518.

Publisher Correction: Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme.

Boos F, Krämer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zöller E, van der Laan M, Savitski MM, Benes V, Herrmann JM

Nature cell biology, 2019

doi:10.1038/s41556-019-0326-1.

Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme.

Boos F, Krämer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zöller E, van der Laan M, Savitski MM, Benes V, Herrmann JM

Nature cell biology, 2019

doi:10.1038/s41556-019-0294-5.

Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease.

Wheeler S, Haberkant P, Bhardwaj M, Tongue P, Ferraz MJ, Halter D, Sprong H, Schmid R, Aerts JMFG, Sullo N, Sillence DJ

Neurobiology of disease, 2019

doi:10.1016/j.nbd.2019.03.005.

A search for ceramide binding proteins using bifunctional lipid analogs yields CERT-related protein StarD7.

Bockelmann S, Mina JGM, Korneev S, Hassan DG, Mueller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, Holthuis JCM

Journal of lipid research, 2018

doi:10.1194/jlr.M082354.

Identification of a feedback loop involving beta-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease.

Schonauer S, Körschen HG, Penno A, Rennhack A, Breiden B, Sandhoff K, Gutbrod K, Dörmann P, Raju DN, Haberkant P, Gerl MJ, Brügger B, Zigdon H, Vardi A, Futerman AH, Thiele C, Wachten D

The Journal of biological chemistry, 2017

doi:10.1074/jbc.m116.762831.

Trifunctional lipid probes for comprehensive studies of single lipid species in living cells.

Höglinger D, Nadler A, Haberkant P, Kirkpatrick J, Schifferer M, Stein F, Hauke S, Porter FD, Schultz C

Proceedings of the National Academy of Sciences of the United States of America, 2017

doi:10.1073/pnas.1611096114.

Sphingosine-1-Phosphate Lyase Deficient Cells as a Tool to Study Protein Lipid Interactions.

Gerl MJ, Bittl V, Kirchner S, Sachsenheimer T, Brunner HL, Lüchtenborg C, Özbalci C, Wiedemann H, Wegehingel S, Nickel W, Haberkant P, Schultz C, Krüger M, Brügger B

PloS one, 2016

doi:10.1371/journal.pone.0153009.

Bifunctional Sphingosine for Cell-Based Analysis of Protein-Sphingolipid Interactions.

Haberkant P, Stein F, Höglinger D, Gerl MJ, Brügger B, Van Veldhoven PP, Krijgsveld J, Gavin AC, Schultz C

ACS chemical biology, 2015

doi:10.1021/acschembio.5b00810.

Intracellular sphingosine releases calcium from lysosomes.

Höglinger D, Haberkant P, Aguilera-Romero A, Riezman H, Porter FD, Platt FM, Galione A, Schultz C

eLife, 2015

doi:10.7554/eLife.10616.

Fat & fabulous: Bifunctional lipids in the spotlight

Haberkant P, Holthuis JC

Biochimica et biophysica acta, 2014

doi:10.1016/j.bbalip.2014.01.003.

In vivo profiling and visualization of cellular protein-lipid interactions using bifunctional fatty acids

Haberkant P, Raijmakers R, Wildwater M, Sachsenheimer T, Brügger B, Maeda K, Houweling M, Gavin AC, Schultz C, van Meer G, Heck AJ, Holthuis JC

Angewandte Chemie (International ed. in English), 2013

doi:10.1002/anie.201210178.