Molecular robotic agents that survey molecular landscapes for information retrieval.

Woo S, Saka SK, Xuan F, Yin P

Nature communications, 2024

doi:10.1038/s41467-024-46978-2.

SpatialData: an open and universal data framework for spatial omics.

Marconato L, Palla G, Yamauchi KA, Virshup I, Heidari E, Treis T, Vierdag WM, Toth M, Stockhaus S, Shrestha RB, Rombaut B, Pollaris L, Lehner L, Vöhringer H, Kats I, Saeys Y, Saka SK, Huber W, Gerstung M, Moore J, Theis FJ, Stegle O

Nature methods, 2024

doi:10.1038/s41592-024-02212-x.

A perspective on FAIR quality control in multiplexed imaging data processing.

Vierdag WAM, Saka SK

Frontiers in bioinformatics, 2024

doi:10.3389/fbinf.2024.1336257.

Thermal-plex: fluidic-free, rapid sequential multiplexed imaging with DNA-encoded thermal channels.

Hong F, Kishi JY, Delgado RN, Jeong J, Saka SK, Su H, Cepko CL, Yin P

Nature methods, 2023

doi:10.1038/s41592-023-02115-3.

Enablers and challenges of spatial omics, a melting pot of technologies.

Alexandrov T, Saez-Rodriguez J, Saka SK

Molecular systems biology, 2023

doi:10.15252/msb.202110571.

Light-Seq: light-directed in situ barcoding of biomolecules in fixed cells and tissues for spatially indexed sequencing.

Kishi JY, Liu N, West ER, Sheng K, Jordanides JJ, Serrata M, Cepko CL, Saka SK, Yin P

Nature methods, 2022

doi:10.1038/s41592-022-01604-1.

Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST.

Schaefer IM, Hemming ML, Lundberg MZ, Serrata MP, Goldaracena I, Liu N, Yin P, Paulo JA, Gygi SP, George S, Morgan JA, Bertagnolli MM, Sicinska ET, Chu C, Zheng S, Mariño-Enríquez A, Hornick JL, Raut CP, Ou WB, Demetri GD, Saka SK, Fletcher JA

British journal of cancer, 2022

doi:10.1038/s41416-022-01990-5.

Spatial mapping of protein composition and tissue organization: a primer for multiplexed antibody-based imaging.

Hickey JW, Neumann EK, Radtke AJ, Camarillo JM, Beuschel RT, Albanese A, McDonough E, Hatler J, Wiblin AE, Fisher J, Croteau J, Small EC, Sood A, Caprioli RM, Angelo RM, Nolan GP, Chung K, Hewitt SM, Germain RN, Spraggins JM, Lundberg E, Snyder MP, Kelleher NL, Saka SK

Nature methods, 2021

doi:10.1038/s41592-021-01316-y.

Multiplexed in situ protein imaging using DNA-barcoded antibodies with extended hybridization chain reactions.

Wang Y, Zeng Y, Saka SK, Xie W, Goldaracena I, Kohman RE, Yin P, Church GM

2020

doi:10.1101/274456.

Single-strand RPA for rapid and sensitive detection of SARS-CoV-2 RNA.

Youngeun Kim, Yaseen AB, Kishi JY, Saka SK, Sheng K, Gopalkrishnan N, Schaus TE, Yin P

medRxiv, 2020

doi:10.1101/2020.08.17.20177006.

Super-resolution labelling with Action-PAINT.

Liu N, Dai M, Saka SK, Yin P

Nature chemistry, 2019

doi:10.1038/s41557-019-0325-7.

Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues.

Saka SK, Wang Y, Kishi JY, Zhu A, Zeng Y, Xie W, Kirli K, Yapp C, Cicconet M, Beliveau BJ, Lapan SW, Yin S, Lin M, Boyden ES, Kaeser PS, Pihan G, Church GM, Yin P

Nature biotechnology, 2019

doi:10.1038/s41587-019-0207-y.

The human body at cellular resolution: the NIH Human Biomolecular Atlas Program.

HuBMAP Consortium (Snyder MP, Lin S, Posgai A, Atkinson M, Regev A, Rood J, Rozenblatt-Rosen O, Gaffney L, Hupalowska A, Satija R, Gehlenborg N, Shendure J, Laskin J, Harbury P, Nystrom NA, Silverstein JC, Bar-Joseph Z, Zhang K, Borner K, Lin Y, Conroy R, Procaccini D, Roy AL, Pillai A, Brown M, Galis ZS, Cai L, Shendure J, Trapnell C, Lin S, Jackson D, Snyder MP, Nolan G, Greenleaf WJ, Lin Y, Plevritis S, Ahadi S, Nevins SA, Lee H, Schuerch CM, Black S, Venkataraaman VG, Esplin E, Horning A, Bahmani A, Zhang K, Sun X, Jain S, Hagood J, Pryhuber G, Kharchenko P, Atkinson M, Bodenmiller B, Brusko T, Clare-Salzler M, Nick H, Otto K, Posgai A, Wasserfall C, Jorgensen M, Brusko M, Maffioletti S, Caprioli RM, Spraggins JM, Gutierrez D, Patterson NH, Neumann EK, Harris R, deCaestecker M, Fogo AB, van de Plas R, Lau K, Cai L, Yuan GC, Zhu Q, Dries R, Yin P, Saka SK, Kishi JY, Wang Y, Goldaracena I, Laskin J, Ye DY, Burnum-Johnson KE, Piehowski PD, Ansong C, Zhu Y, Harbury P, Desai T, Mulye J, Chou P, Nagendran M, Bar-Joseph Z, Teichmann SA, Paten B, Murphy RF, Ma J, Kiselev VY, Kingsford C, Ricarte A, Keays M, Akoju SA, Ruffalo M, Gehlenborg N, Kharchenko P, Vella M, McCallum C, Borner K, Cross LE, Friedman SH, Heiland R, Herr B, Macklin P, Quardokus EM, Record L, Sluka JP, Weber GM, Nystrom NA, Silverstein JC, Blood PD, Ropelewski AJ, Shirey WE, Scibek RM, Mabee P, Lenhardt WC, Robasky K, Michailidis S, Satija R, Marioni J, Regev A, Butler A, Stuart T, Fisher E, Ghazanfar S, Rood J, Gaffney L, Eraslan G, Biancalani T, Vaishnav ED, Conroy R, Procaccini D, Roy A, Pillai A, Brown M, Galis Z, Srinivas P, Pawlyk A, Sechi S, Wilder E, Anderson J)

NATURE, 2019

doi:10.1038/s41586-019-1629-x.

SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues.

Kishi JY, Lapan SW, Beliveau BJ, West ER, Zhu A, Sasaki HM, Saka SK, Wang Y, Cepko CL, Yin P

Nature methods, 2019

doi:10.1038/s41592-019-0404-0.

OligoMiner provides a rapid, flexible environment for the design of genome-scale oligonucleotide in situ hybridization probes.

Beliveau BJ, Kishi JY, Nir G, Sasaki HM, Saka SK, Nguyen SC, Wu CT, Yin P

Proceedings of the National Academy of Sciences of the United States of America, 2018

doi:10.1073/pnas.1714530115.

Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT.

Schueder F, Lara-Gutiérrez J, Beliveau BJ, Saka SK, Sasaki HM, Woehrstein JB, Strauss MT, Grabmayr H, Yin P, Jungmann R

Nature communications, 2017

doi:10.1038/s41467-017-02028-8.

A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry.

Kabatas S, Vreja IC, Saka SK, Höschen C, Kröhnert K, Opazo F, Rizzoli SO, Diederichsen U

Chemical communications (Cambridge, England), 2015

doi:10.1039/c5cc03895b.

Mapping molecules in scanning far-field fluorescence nanoscopy.

Ta H, Keller J, Haltmeier M, Saka SK, Schmied J, Opazo F, Tinnefeld P, Munk A, Hell SW

Nature communications, 2015

doi:10.1038/ncomms8977.

Secondary-ion mass spectrometry of genetically encoded targets.

Vreja IC, Kabatas S, Saka SK, Kröhnert K, Höschen C, Opazo F, Diederichsen U, Rizzoli SO

Angewandte Chemie (International ed. in English), 2015

doi:10.1002/anie.201411692.

Multi-protein assemblies underlie the mesoscale organization of the plasma membrane.

Saka SK, Honigmann A, Eggeling C, Hell SW, Lang T, Rizzoli SO

Nature communications, 2014

doi:10.1038/ncomms5509.

Correlated optical and isotopic nanoscopy.

Saka SK, Vogts A, Kröhnert K, Hillion F, Rizzoli SO, Wessels JT

Nature communications, 2014

doi:10.1038/ncomms4664.

Super-resolution imaging prompts re-thinking of cell biology mechanisms: selected cases using stimulated emission depletion microscopy.

Saka S, Rizzoli SO

BioEssays : news and reviews in molecular, cellular and developmental biology, 2012

doi:10.1002/bies.201100080.