Single-cell-resolved interspecies comparison identifies a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19.

Peidli S, Nouailles G, Wyler E, Adler MJ, Kunder S, Voß A, Kazmierski J, Pott F, Pennitz P, Postmus D, Alves LGT, Goffinet C, Gruber DA, Blüthgen N, Witzenrath M, Trimpert J, Landthaler M, Praktiknjo DS

bioRxiv, 2023

doi:10.1101/2023.08.25.551434.

scPerturb: harmonized single-cell perturbation data.

Peidli S, Green TD, Shen C, Gross T, Min J, Garda S, Yuan B, Schumacher LJ, Taylor-King JP, Marks DS, Luna A, Blüthgen N, Sander C

Nature Methods, 2024

doi:10.1038/s41592-023-02144-y.

Live-attenuated vaccine sCPD9 elicits superior mucosal and systemic immunity to SARS-CoV-2 variants in hamsters.

Nouailles Geraldine , Adler M. Julia , Pennitz Peter , Peidli Stefan , Alves Teixeira Gustavo Luiz , Baumgardt Morris , Bushe Judith , Voss Anne , Langenhagen Alina , Langner Christine , Vidal Martin Ricardo , Pott Fabian , Kazmierski Julia , Ebenig Aileen , Lange V. Mona , Mühlebach D. Michael , Goekeri Cengiz , Simmons Szandor , Xing Na , Abdelgawad Azza , Herwig Susanne , Cichon Günter , Niemeyer Daniela , Drosten Christian , Goffinet Christine , Landthaler Markus , Blüthgen Nils , Wu Haibo , Witzenrath Martin , Gruber D. Achim , Praktiknjo D. Samantha , Osterrieder Nikolaus , Wyler Emanuel , Kunec Dusan , Trimpert Jakob

Nature microbiology, 2023

doi:10.1038/s41564-023-01352-8.

Key benefits of dexamethasone and antibody treatment in COVID-19 hamster models revealed by single-cell transcriptomics.

Wyler E , Adler JM , Eschke K , Teixeira Alves G , Peidli S , Pott F , Kazmierski J , Michalick L , Kershaw O , Bushe J , Andreotti S , Pennitz P , Abdelgawad A , Postmus D , Goffinet C , Kreye J , Reincke SM , Prüss H , Blüthgen N , Gruber AD , Kuebler WM , Witzenrath M , Landthaler M , Nouailles G , Trimpert J

Molecular Therapy, 2022

doi:10.1016/j.ymthe.2022.03.014.

Mitogen‐activated protein kinase activity drives cell trajectories in colorectal cancer.

Uhlitz F, Bischoff P, Peidli S, Sieber A, Trinks A, Lüthen M, Obermayer B, Blanc E, Ruchiy Y, Sell T, Mamlouk S, Arsie R, Wei T, Klotz-Noack K, Schwarz RF, Sawitzki B, Kamphues C, Beule D, Landthaler M, Sers C, Horst D, Blüthgen N, Morkel M

EMBO molecular medicine, 2021

doi:10.15252/emmm.202114123.

Generalizing RNA velocity to transient cell states through dynamical modeling.

Bergen V, Lange M, Peidli S, Wolf FA, Theis FJ

Nature Biotechnology, 2020

doi:10.1038/s41587-020-0591-3.