Histone editing elucidates the functional roles of H3K27 methylation and acetylation in mammals.

Sankar A, Mohammad F, Sundaramurthy AK, Wang H, Lerdrup M, Tatar T, Helin K

Nature genetics, 2022

doi:10.1038/s41588-022-01091-2.

Genetic insights into biological mechanisms governing human ovarian ageing.

Ruth KS, Day FR, Hussain J. et al.

Nature, 2021

doi:10.1038/s41586-021-03779-7.

PR-DUB maintains the expression of critical genes through FOXK1/2- and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination.

Kolovos P, Nishimura K, Sankar A, Sidoli S, Cloos PA, Helin K, Christensen J

Genome research, 2020

doi:10.1101/gr.261016.120.

KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes.

Sankar A, Lerdrup M, Manaf A, Johansen JV, Gonzalez JM, Borup R, Blanshard R, Klungland A, Hansen K, Andersen CY, Dahl JA, Helin K, Hoffmann ER

Nature cell biology, 2020

doi:10.1038/s41556-020-0494-z.

The lysine demethylase KDM5B regulates islet function and glucose homeostasis.

Backe MB, Jin C, Andreone L, Sankar A, Agger K, Helin K, Madsen AN, Poulsen SS, Bysani M, Bacos K, Ling C, Perone MJ, Holst B, Mandrup-Poulsen T

Journal of diabetes research, 2019

doi:10.1155/2019/5451038.

Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation development.

Sankar A, Kooistra SM, Gonzalez JM, Ohlsson C, Poutanen M, Helin K

Development (Cambridge, England), 2017

doi:10.1242/dev.155473.

ZFP57 maintains the parent-of-origin-specific expression of the imprinted genes and differentially affects non-imprinted targets in mouse embryonic stem cells.

Riso V, Cammisa M, Kukreja H, Anvar Z, Verde G, Sparago A, Acurzio B, Lad S, Lonardo E, Sankar A, Helin K, Feil R, Fico A, Angelini C, Grimaldi G, Riccio A

Nucleic acids research, 2016

doi:10.1093/nar/gkw505.

SWI/SNF subunits SMARCA4, SMARCD2 and DPF2 collaborate in MLL-rearranged leukaemia maintenance.

Cruickshank VA, Sroczynska P, Sankar A, Miyagi S, Rundsten CF, Johansen JV, Helin K

PloS one, 2015

doi:10.1371/journal.pone.0142806.

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D

Nature, 2011

doi:10.1038/nature10547.